Click here to switch to the map view.

The map label for this gene is pnuC [H]

Identifier: 146282574

GI number: 146282574

Start: 2431237

End: 2431797

Strand: Direct

Name: pnuC [H]

Synonym: PST_2226

Alternate gene names: 146282574

Gene position: 2431237-2431797 (Clockwise)

Preceding gene: 146282573

Following gene: 146282575

Centisome position: 53.23

GC content: 66.13

Gene sequence:

>561_bases
ATGTCGCTTCTCGAACTGATCGCCTCGCTGCTGGGCGTTATCGCCGTCTGGCTGACCGTGCGACAGAACAGCTGGTGCTG
GCCCATCGGGCTGGGCATGGTGTCGCTGTATGCGTGGTTTTTCTTCGATGCCAGGCTGTACTCCCAGGTGCTGTTGCACG
GCGTCTTCGCGGCGATGCAGCTGTATGGCTGGTGGGCCTGGACCCGCGGCGCCGATGGACACGGCCGGCGCGTGAGCCTG
GCCAGCGGGCCGGAAGTGCTGGTCGGCATCGGCATGGCGGTGCTAGGCAGCCTGCTGCTCGGCAGCGCAATGGCTCGCTT
CACCGAGGCGGCGTTTCCCTGGATCGATGCCAGCCTGACCGCCTTCAGCCTGCTCGCGCAGCTGTGGATGGCACTCAAGC
GCCTGCAGTGCTGGCCGCTGTGGATCGTGGTCGATGCCTTGTTTGTCGGCTTCTTCAGCTTCCAGGGCTACTGGTTGACG
GCCGGGCTCTACGCGCTGTTCACCGCGCTGGCGGTGATGGGGCTGCGTGAATGGCGTGCGACCCTGGTGGCCGCCCGATG
A

Upstream 100 bases:

>100_bases
CAGGTCGATGTCGGGGTCGTTCAATCTCGCCTGCCGCGATCCGGACGAGGCCCGGCTCCGTTATGATCGCGCCCCTCGTT
CTTCGCCACCGGTCACCGCC

Downstream 100 bases:

>100_bases
AAGTCGTCGTGCTCACCGGACCGGAATCCACCGGCAAGAGCTGGCTGGCCGATCGCTTGCGACGCCGCTTTGGCGGCCTC
GTGGTCGACGAGTACGTGCG

Product: transporter

Products: nicotinamide nucleotide [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MSLLELIASLLGVIAVWLTVRQNSWCWPIGLGMVSLYAWFFFDARLYSQVLLHGVFAAMQLYGWWAWTRGADGHGRRVSL
ASGPEVLVGIGMAVLGSLLLGSAMARFTEAAFPWIDASLTAFSLLAQLWMALKRLQCWPLWIVVDALFVGFFSFQGYWLT
AGLYALFTALAVMGLREWRATLVAAR

Sequences:

>Translated_186_residues
MSLLELIASLLGVIAVWLTVRQNSWCWPIGLGMVSLYAWFFFDARLYSQVLLHGVFAAMQLYGWWAWTRGADGHGRRVSL
ASGPEVLVGIGMAVLGSLLLGSAMARFTEAAFPWIDASLTAFSLLAQLWMALKRLQCWPLWIVVDALFVGFFSFQGYWLT
AGLYALFTALAVMGLREWRATLVAAR
>Mature_185_residues
SLLELIASLLGVIAVWLTVRQNSWCWPIGLGMVSLYAWFFFDARLYSQVLLHGVFAAMQLYGWWAWTRGADGHGRRVSLA
SGPEVLVGIGMAVLGSLLLGSAMARFTEAAFPWIDASLTAFSLLAQLWMALKRLQCWPLWIVVDALFVGFFSFQGYWLTA
GLYALFTALAVMGLREWRATLVAAR

Specific function: Required for nicotinamide riboside transport across the inner membrane [H]

COG id: COG3201

COG function: function code H; Nicotinamide mononucleotide transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006419 [H]

Pfam domain/function: PF04973 NMN_transporter [H]

EC number: NA

Molecular weight: Translated: 20716; Mature: 20585

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLELIASLLGVIAVWLTVRQNSWCWPIGLGMVSLYAWFFFDARLYSQVLLHGVFAAMQ
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYGWWAWTRGADGHGRRVSLASGPEVLVGIGMAVLGSLLLGSAMARFTEAAFPWIDASLT
HHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
AFSLLAQLWMALKRLQCWPLWIVVDALFVGFFSFQGYWLTAGLYALFTALAVMGLREWRA
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
TLVAAR
HHHCCC
>Mature Secondary Structure 
SLLELIASLLGVIAVWLTVRQNSWCWPIGLGMVSLYAWFFFDARLYSQVLLHGVFAAMQ
CHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYGWWAWTRGADGHGRRVSLASGPEVLVGIGMAVLGSLLLGSAMARFTEAAFPWIDASLT
HHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
AFSLLAQLWMALKRLQCWPLWIVVDALFVGFFSFQGYWLTAGLYALFTALAVMGLREWRA
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
TLVAAR
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nicotinamide nucleotide [Periplasm] [C]

Specific reaction: nicotinamide nucleotide [Periplasm] = nicotinamide nucleotide [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2198247; 11677609 [H]