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The map label for this gene is ompR [H]

Identifier: 145301083

GI number: 145301083

Start: 4549361

End: 4550083

Strand: Direct

Name: ompR [H]

Synonym: ASA_4252

Alternate gene names: 145301083

Gene position: 4549361-4550083 (Clockwise)

Preceding gene: 145301082

Following gene: 145301084

Centisome position: 96.75

GC content: 62.52

Gene sequence:

>723_bases
ATGTCAACGAGCAAACAACTGCTGATCGTCGACGACGACCAAGAGATCCGCGAGCTGCTCAATGAATACCTGACCAGGGC
CGGTTTCCAGGTATTGACGGCGGCGGAAGGCAACGAGATGCGCCAGCAGCTCGCCCTGCACAGCCCGGACCTGATTATTC
TCGATATCATGATGCCAGGCGACGACGGCTTTACCCTGTGCCAACAGATCCGTCGCGACTCCCAGGTACCCATCATAATG
CTGACCGCAGCCTCCGATGAGGCAGACAGGGTGATCGGCCTCGAACTCGGCGCCGACGACTACATCGCCAAGCCGTTCAG
CCCGCGCGAGCTGCAGGCTCGCATCAAGGCGTTGCTGCGCCGCGCCGAATTCCGCCAGCCGGAAAAAGAGAAAGAACCGA
GCCGCCGCCTGCGTTTTGCCGAATGGACCCTGGACACCCTGAGCCACCAGCTGACCCACGACGATGGCAGCCTGCTGGAT
CTCTCCGGCAGCGACGCCCTGCTGCTCGGCATGTTCCTGCAGCAACCCGGCGTGGTGCTGGACAGGGACACCATCTCGGA
CGCGACCCGGGGCCGCGAGAGCCTGCCGATGGAGCGCGGCATCGACGTGCAGATCAGCCGTCTGCGCCAGAAGCTGGGTG
ACAACGGCAAGAGCCCGCGCATCATCAAGACCATACGCGGCAGTGGCTATATGCTGATTGCCGAAGTACACGAGATCCCG
TGA

Upstream 100 bases:

>100_bases
GGATATTGCCCATAACCTCACATTAGATGGGGGGCTTGCTTGCTTTTTGCTCCCCCGACAGGTTCAATCTGCACAAAAAA
ATGGGTGGATGCACATACAT

Downstream 100 bases:

>100_bases
AGGGTAAAAAGGTAGCAACGGCATGCTGAACGACAAAAGGCACGAGATCCCATGAGGAGTGGCTGGTTCTGGCGGGCGCT
GGTTCCCCGCTCCCTGCTGT

Product: two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MSTSKQLLIVDDDQEIRELLNEYLTRAGFQVLTAAEGNEMRQQLALHSPDLIILDIMMPGDDGFTLCQQIRRDSQVPIIM
LTAASDEADRVIGLELGADDYIAKPFSPRELQARIKALLRRAEFRQPEKEKEPSRRLRFAEWTLDTLSHQLTHDDGSLLD
LSGSDALLLGMFLQQPGVVLDRDTISDATRGRESLPMERGIDVQISRLRQKLGDNGKSPRIIKTIRGSGYMLIAEVHEIP

Sequences:

>Translated_240_residues
MSTSKQLLIVDDDQEIRELLNEYLTRAGFQVLTAAEGNEMRQQLALHSPDLIILDIMMPGDDGFTLCQQIRRDSQVPIIM
LTAASDEADRVIGLELGADDYIAKPFSPRELQARIKALLRRAEFRQPEKEKEPSRRLRFAEWTLDTLSHQLTHDDGSLLD
LSGSDALLLGMFLQQPGVVLDRDTISDATRGRESLPMERGIDVQISRLRQKLGDNGKSPRIIKTIRGSGYMLIAEVHEIP
>Mature_239_residues
STSKQLLIVDDDQEIRELLNEYLTRAGFQVLTAAEGNEMRQQLALHSPDLIILDIMMPGDDGFTLCQQIRRDSQVPIIML
TAASDEADRVIGLELGADDYIAKPFSPRELQARIKALLRRAEFRQPEKEKEPSRRLRFAEWTLDTLSHQLTHDDGSLLDL
SGSDALLLGMFLQQPGVVLDRDTISDATRGRESLPMERGIDVQISRLRQKLGDNGKSPRIIKTIRGSGYMLIAEVHEIP

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=41.8803418803419, Blast_Score=186, Evalue=1e-48,
Organism=Escherichia coli, GI1790863, Length=236, Percent_Identity=34.3220338983051, Blast_Score=150, Evalue=6e-38,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=39.5652173913043, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1788394, Length=243, Percent_Identity=35.3909465020576, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=37.3913043478261, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=35.7758620689655, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI145693140, Length=239, Percent_Identity=33.8912133891213, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=38.1578947368421, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=36.5638766519824, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI87082012, Length=232, Percent_Identity=34.9137931034483, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1786911, Length=228, Percent_Identity=32.8947368421053, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=31.5789473684211, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=30.1310043668122, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=31.1688311688312, Blast_Score=97, Evalue=6e-22,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=39.0243902439024, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787487, Length=142, Percent_Identity=34.5070422535211, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788550, Length=167, Percent_Identity=29.3413173652695, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27032; Mature: 26901

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSKQLLIVDDDQEIRELLNEYLTRAGFQVLTAAEGNEMRQQLALHSPDLIILDIMMPG
CCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCEEEEEEEECC
DDGFTLCQQIRRDSQVPIIMLTAASDEADRVIGLELGADDYIAKPFSPRELQARIKALLR
CCHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEECCCCHHCCCCCHHHHHHHHHHHHH
RAEFRQPEKEKEPSRRLRFAEWTLDTLSHQLTHDDGSLLDLSGSDALLLGMFLQQPGVVL
HHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHCCCCEE
DRDTISDATRGRESLPMERGIDVQISRLRQKLGDNGKSPRIIKTIRGSGYMLIAEVHEIP
ECCHHHHHHCCHHCCCHHCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEECCCC
>Mature Secondary Structure 
STSKQLLIVDDDQEIRELLNEYLTRAGFQVLTAAEGNEMRQQLALHSPDLIILDIMMPG
CCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCEEEEEEEECC
DDGFTLCQQIRRDSQVPIIMLTAASDEADRVIGLELGADDYIAKPFSPRELQARIKALLR
CCHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEECCCCHHCCCCCHHHHHHHHHHHHH
RAEFRQPEKEKEPSRRLRFAEWTLDTLSHQLTHDDGSLLDLSGSDALLLGMFLQQPGVVL
HHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHCCCCEE
DRDTISDATRGRESLPMERGIDVQISRLRQKLGDNGKSPRIIKTIRGSGYMLIAEVHEIP
ECCHHHHHHCCHHCCCHHCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]