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The map label for this gene is katE [H]

Identifier: 145300894

GI number: 145300894

Start: 4339988

End: 4341436

Strand: Direct

Name: katE [H]

Synonym: ASA_4040

Alternate gene names: 145300894

Gene position: 4339988-4341436 (Clockwise)

Preceding gene: 145300891

Following gene: 145300896

Centisome position: 92.29

GC content: 62.53

Gene sequence:

>1449_bases
ATGACTGACAATACACTGCACAGTGCCAACGGCGCCCCAGTCGTCGACAACAACAACAGCCTTACTGCCGGTCCCCGCGG
CCCCGTGCTGATGCAAGATATCTGGTTGATGGAGAAACTCGCCCACTTCGACCGCGAGCGCATTCCCGAGCGGGTGGTTC
ACGCCAAAGGCTCGGGCGCCTACGGCACCTTTACCGTGACCCACGACATCAGCGCGTTCAGCAAGGCCGACCTGTTCAAC
GCCATCGGCAAGCAGACCCCGGTCTTCCTGCGCTTCTCCACCGTAGCCGGTGAGAAGGGGGCTGCCGATGCCGAGCGGGA
CGTACGCGGCTTCGCCCTCAAGTTCTACACAGAGCAGGGCAACTGGGATCTGGTGGGCAACAACACCCCGGTCTTTTTCA
TCCGCGAACCGCTGAAATTCCCCGATTTCATCCACACCCAGAAGCGGGATCCGCGCACCAACCTGCGCAGTGCCACCGCC
GCCTGGGACTTCTGGTCACGCCATCCCGAATCCCTGCATCAGGTCACCATACTGTTCAGCGATCGCGGCATTCCCAAGAG
TCTGCGGGAGATGAACGGCTACGGCAGCCACACCTTCAGCTTTATCAACGACGCCAACGAACGCTTCTGGGTCAAATTCC
ACTTCAAGACCGAGCAGGGTCACAGCTTCTACACAGATGAAGAGGCGGCCAATGTCGTCGGTCAGGATAGAGAGACCAGC
CAGACCGATCTGTTCAATGCCATTGAGCGGGGCGACTTCCCGCGCTGGAAGGTCTATGTGCAGGTGATGCCGGAGGCCGA
TGCCCAGAGCTACCGGATCCACCCGTTCGACCTCACCAAGGTGTGGCCGCACAGCGACTATCCGCTAATCCCGGTAGGCG
TGCTGGAGCTCAACCAGAACCCGGACAACTACTTCGCCCACGTGGAGCAGGCTGCGTTCACCCCAGCCAACGTGGTGCCC
GGCATCGGCTTCTCGCCGGATCGCATGCTGCAGGGACGGCTCTTCTCCTACGGCGACACCCAGCGCTATCGCCTCGGGGT
CAACCACGGCCTGCTGCCGGTCAACGCCCCGCGCTGCCCATTCCGCCACGGTGCCCATCGTGATGGCGCCATGCGCAGCG
ACAGCAATGGCGGCGCCAGTCCCAACTATCAGCCGAACCGCTTTGGCACCCAGCAGCCGAGCGAGCAGCACGAACCGGCC
TTGAGTCTGGAAGGGGCTGCCCTGCACTACGACTTCCGTGACTACGACAGCGATTACTACAGCCAGCCGGGCAAGCTGTT
CCGCATCATGGATGAGGGGCAGCGCTCGCGCCTCGCCGCCAATATGGCACGTTCCCTCATCAACGTGGAGGATGACGCCA
TCGTCGTCGCCCAGCTCCGGCATCTTGAGCAGGCCGACCCCGAGTACGCCAAGCGGGTGGAGCTGGCACTGGCTGCGCTG
CAACGCTAA

Upstream 100 bases:

>100_bases
AATACCCATTTGCGATACCTATCAAAGGGCTAGGAAAGGCCCATTGGCCCATGAGGAGCGGGATCCGTAGGCTGACCCCT
ATCAACAAGGAGAGACATTC

Downstream 100 bases:

>100_bases
GCGACCAGGATGCAATAAAAGAACGGGGGCCGGCGGGCCCCCTTCTTTCAACCCCAGTACACGGGATAAATTCTGAGCCC
ACGGCACGTCGAGTCTTGCA

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 481

Protein sequence:

>482_residues
MTDNTLHSANGAPVVDNNNSLTAGPRGPVLMQDIWLMEKLAHFDRERIPERVVHAKGSGAYGTFTVTHDISAFSKADLFN
AIGKQTPVFLRFSTVAGEKGAADAERDVRGFALKFYTEQGNWDLVGNNTPVFFIREPLKFPDFIHTQKRDPRTNLRSATA
AWDFWSRHPESLHQVTILFSDRGIPKSLREMNGYGSHTFSFINDANERFWVKFHFKTEQGHSFYTDEEAANVVGQDRETS
QTDLFNAIERGDFPRWKVYVQVMPEADAQSYRIHPFDLTKVWPHSDYPLIPVGVLELNQNPDNYFAHVEQAAFTPANVVP
GIGFSPDRMLQGRLFSYGDTQRYRLGVNHGLLPVNAPRCPFRHGAHRDGAMRSDSNGGASPNYQPNRFGTQQPSEQHEPA
LSLEGAALHYDFRDYDSDYYSQPGKLFRIMDEGQRSRLAANMARSLINVEDDAIVVAQLRHLEQADPEYAKRVELALAAL
QR

Sequences:

>Translated_482_residues
MTDNTLHSANGAPVVDNNNSLTAGPRGPVLMQDIWLMEKLAHFDRERIPERVVHAKGSGAYGTFTVTHDISAFSKADLFN
AIGKQTPVFLRFSTVAGEKGAADAERDVRGFALKFYTEQGNWDLVGNNTPVFFIREPLKFPDFIHTQKRDPRTNLRSATA
AWDFWSRHPESLHQVTILFSDRGIPKSLREMNGYGSHTFSFINDANERFWVKFHFKTEQGHSFYTDEEAANVVGQDRETS
QTDLFNAIERGDFPRWKVYVQVMPEADAQSYRIHPFDLTKVWPHSDYPLIPVGVLELNQNPDNYFAHVEQAAFTPANVVP
GIGFSPDRMLQGRLFSYGDTQRYRLGVNHGLLPVNAPRCPFRHGAHRDGAMRSDSNGGASPNYQPNRFGTQQPSEQHEPA
LSLEGAALHYDFRDYDSDYYSQPGKLFRIMDEGQRSRLAANMARSLINVEDDAIVVAQLRHLEQADPEYAKRVELALAAL
QR
>Mature_481_residues
TDNTLHSANGAPVVDNNNSLTAGPRGPVLMQDIWLMEKLAHFDRERIPERVVHAKGSGAYGTFTVTHDISAFSKADLFNA
IGKQTPVFLRFSTVAGEKGAADAERDVRGFALKFYTEQGNWDLVGNNTPVFFIREPLKFPDFIHTQKRDPRTNLRSATAA
WDFWSRHPESLHQVTILFSDRGIPKSLREMNGYGSHTFSFINDANERFWVKFHFKTEQGHSFYTDEEAANVVGQDRETSQ
TDLFNAIERGDFPRWKVYVQVMPEADAQSYRIHPFDLTKVWPHSDYPLIPVGVLELNQNPDNYFAHVEQAAFTPANVVPG
IGFSPDRMLQGRLFSYGDTQRYRLGVNHGLLPVNAPRCPFRHGAHRDGAMRSDSNGGASPNYQPNRFGTQQPSEQHEPAL
SLEGAALHYDFRDYDSDYYSQPGKLFRIMDEGQRSRLAANMARSLINVEDDAIVVAQLRHLEQADPEYAKRVELALAALQ
R

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=482, Percent_Identity=52.2821576763486, Blast_Score=496, Evalue=1e-140,
Organism=Escherichia coli, GI48994891, Length=395, Percent_Identity=46.8354430379747, Blast_Score=352, Evalue=4e-98,
Organism=Caenorhabditis elegans, GI71998444, Length=484, Percent_Identity=52.6859504132231, Blast_Score=509, Evalue=1e-145,
Organism=Caenorhabditis elegans, GI25151141, Length=478, Percent_Identity=51.4644351464435, Blast_Score=487, Evalue=1e-138,
Organism=Caenorhabditis elegans, GI25147792, Length=479, Percent_Identity=50.9394572025052, Blast_Score=486, Evalue=1e-138,
Organism=Saccharomyces cerevisiae, GI6320462, Length=491, Percent_Identity=44.1955193482688, Blast_Score=387, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6321525, Length=381, Percent_Identity=45.4068241469816, Blast_Score=338, Evalue=9e-94,
Organism=Drosophila melanogaster, GI17981717, Length=447, Percent_Identity=50.1118568232662, Blast_Score=454, Evalue=1e-128,
Organism=Drosophila melanogaster, GI19920968, Length=450, Percent_Identity=45.5555555555556, Blast_Score=418, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 54546; Mature: 54415

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDNTLHSANGAPVVDNNNSLTAGPRGPVLMQDIWLMEKLAHFDRERIPERVVHAKGSGA
CCCCCEECCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCC
YGTFTVTHDISAFSKADLFNAIGKQTPVFLRFSTVAGEKGAADAERDVRGFALKFYTEQG
EEEEEEEECCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHCCCEEEEEEEEECC
NWDLVGNNTPVFFIREPLKFPDFIHTQKRDPRTNLRSATAAWDFWSRHPESLHQVTILFS
CEEEECCCCCEEEEECCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEE
DRGIPKSLREMNGYGSHTFSFINDANERFWVKFHFKTEQGHSFYTDEEAANVVGQDRETS
CCCCCHHHHHHCCCCCEEEHHHCCCCCEEEEEEEEECCCCCCEECCHHHHHHCCCCCCCH
QTDLFNAIERGDFPRWKVYVQVMPEADAQSYRIHPFDLTKVWPHSDYPLIPVGVLELNQN
HHHHHHHHHHCCCCCEEEEEEEECCCCCCCEEECCEECCEECCCCCCCEEEEEEEEECCC
PDNYFAHVEQAAFTPANVVPGIGFSPDRMLQGRLFSYGDTQRYRLGVNHGLLPVNAPRCP
CCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCHHCCCCCCCEEEEECCCCEECCCCCCCC
FRHGAHRDGAMRSDSNGGASPNYQPNRFGTQQPSEQHEPALSLEGAALHYDFRDYDSDYY
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCEEECCEEEEEEHHHCCCHHH
SQPGKLFRIMDEGQRSRLAANMARSLINVEDDAIVVAQLRHLEQADPEYAKRVELALAAL
CCCCCEEEEHHCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCHHHHHHHHHHHHHH
QR
CC
>Mature Secondary Structure 
TDNTLHSANGAPVVDNNNSLTAGPRGPVLMQDIWLMEKLAHFDRERIPERVVHAKGSGA
CCCCEECCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCC
YGTFTVTHDISAFSKADLFNAIGKQTPVFLRFSTVAGEKGAADAERDVRGFALKFYTEQG
EEEEEEEECCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHCCCEEEEEEEEECC
NWDLVGNNTPVFFIREPLKFPDFIHTQKRDPRTNLRSATAAWDFWSRHPESLHQVTILFS
CEEEECCCCCEEEEECCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEE
DRGIPKSLREMNGYGSHTFSFINDANERFWVKFHFKTEQGHSFYTDEEAANVVGQDRETS
CCCCCHHHHHHCCCCCEEEHHHCCCCCEEEEEEEEECCCCCCEECCHHHHHHCCCCCCCH
QTDLFNAIERGDFPRWKVYVQVMPEADAQSYRIHPFDLTKVWPHSDYPLIPVGVLELNQN
HHHHHHHHHHCCCCCEEEEEEEECCCCCCCEEECCEECCEECCCCCCCEEEEEEEEECCC
PDNYFAHVEQAAFTPANVVPGIGFSPDRMLQGRLFSYGDTQRYRLGVNHGLLPVNAPRCP
CCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCHHCCCCCCCEEEEECCCCEECCCCCCCC
FRHGAHRDGAMRSDSNGGASPNYQPNRFGTQQPSEQHEPALSLEGAALHYDFRDYDSDYY
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCEEECCEEEEEEHHHCCCHHH
SQPGKLFRIMDEGQRSRLAANMARSLINVEDDAIVVAQLRHLEQADPEYAKRVELALAAL
CCCCCEEEEHHCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCHHHHHHHHHHHHHH
QR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]