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The map label for this gene is csgD [H]

Identifier: 145300854

GI number: 145300854

Start: 4291038

End: 4291640

Strand: Direct

Name: csgD [H]

Synonym: ASA_3998

Alternate gene names: 145300854

Gene position: 4291038-4291640 (Clockwise)

Preceding gene: 145300851

Following gene: 145300855

Centisome position: 91.25

GC content: 56.22

Gene sequence:

>603_bases
ATGACCACCCCATACACCATAGTCGTACTGGTGACTGAAAATAATGTGCAGGCGACCAGTTTTCAGAGCTATCTGGCTGA
GCAGCTGGCACTCCCCATCCTGCTGGATGGGCGAGAGTCACACCCATTATTTCTGGTCGATCTGGATTACCTCAAGTCGA
GCCAGCAGAGTGGGTGGCCGAGGGAGATCTCCAGTCGCTTCGGGGAAGCCAACACGATATTGCTCAATGCCCCGACCAGC
ACAGATCGCGAGTTGTTGCTGATGTGGCCTCACACCAGCGGACTCTTCTTCCGCCAGGATCGGCTGGTGCTCGGCATTCG
CAAGGTGTTGCAGGGGGAGTACTGGATCCCGCGCCATTTGCTGTGCGATCTGGTCAACTACTACCGCAAGGGGGGAGAAC
ATCACCTGCGCAACCAGACGCTGCTGACTGCGCGCGAGCAGGAGATCATCCGCTACCTGATGACGGGTGCCTCCAATACC
GAGATTGCCGACAGCCTGTTTGTGAGCGAGCACACCATCAAGTCCCACCTCTATAACGTCTTCAAGAAATTGAACGTCAG
GAACCGGTTGCAGGCGGTGAGCTGGGCCAAAGAATATCTCTGA

Upstream 100 bases:

>100_bases
ACTGGCGTCTAATGCTTTTTTAATGCTGCAGCGTTTGGGGGGCTTGGTACTCTCTGCTGCCAAAAAAACCATGGCCTGAA
TGTTCAAGGACGTGCTCTTC

Downstream 100 bases:

>100_bases
AATCGATGGAGATGATGGATAAAACCTGTCTATTCATCCAGTAGTCTCTATGCCATACTGATTCGCTCTGATTTGTGTAT
CGAGCGTGCAACAAGATGGA

Product: LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MTTPYTIVVLVTENNVQATSFQSYLAEQLALPILLDGRESHPLFLVDLDYLKSSQQSGWPREISSRFGEANTILLNAPTS
TDRELLLMWPHTSGLFFRQDRLVLGIRKVLQGEYWIPRHLLCDLVNYYRKGGEHHLRNQTLLTAREQEIIRYLMTGASNT
EIADSLFVSEHTIKSHLYNVFKKLNVRNRLQAVSWAKEYL

Sequences:

>Translated_200_residues
MTTPYTIVVLVTENNVQATSFQSYLAEQLALPILLDGRESHPLFLVDLDYLKSSQQSGWPREISSRFGEANTILLNAPTS
TDRELLLMWPHTSGLFFRQDRLVLGIRKVLQGEYWIPRHLLCDLVNYYRKGGEHHLRNQTLLTAREQEIIRYLMTGASNT
EIADSLFVSEHTIKSHLYNVFKKLNVRNRLQAVSWAKEYL
>Mature_199_residues
TTPYTIVVLVTENNVQATSFQSYLAEQLALPILLDGRESHPLFLVDLDYLKSSQQSGWPREISSRFGEANTILLNAPTST
DRELLLMWPHTSGLFFRQDRLVLGIRKVLQGEYWIPRHLLCDLVNYYRKGGEHHLRNQTLLTAREQEIIRYLMTGASNTE
IADSLFVSEHTIKSHLYNVFKKLNVRNRLQAVSWAKEYL

Specific function: The master regulator for adhesive curli fimbriae expression; necessary for transcription of the csgBAC/ymdA operon. Plays a positive role in biofilm formation. May have the capability to respond to starvation and/or high cell density by activating csgBA t

COG id: COG2771

COG function: function code K; DNA-binding HTH domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH luxR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787277, Length=207, Percent_Identity=36.7149758454106, Blast_Score=119, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016032
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE [H]

EC number: NA

Molecular weight: Translated: 23164; Mature: 23033

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPYTIVVLVTENNVQATSFQSYLAEQLALPILLDGRESHPLFLVDLDYLKSSQQSGWP
CCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCEEECCCCCCCEEEEEHHHHHCCCCCCCH
REISSRFGEANTILLNAPTSTDRELLLMWPHTSGLFFRQDRLVLGIRKVLQGEYWIPRHL
HHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCCCEEECCHHHHHHHHHHCCCCCCHHHH
LCDLVNYYRKGGEHHLRNQTLLTAREQEIIRYLMTGASNTEIADSLFVSEHTIKSHLYNV
HHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
FKKLNVRNRLQAVSWAKEYL
HHHHCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTPYTIVVLVTENNVQATSFQSYLAEQLALPILLDGRESHPLFLVDLDYLKSSQQSGWP
CCCEEEEEEEECCCCCHHHHHHHHHHHHCCCEEECCCCCCCEEEEEHHHHHCCCCCCCH
REISSRFGEANTILLNAPTSTDRELLLMWPHTSGLFFRQDRLVLGIRKVLQGEYWIPRHL
HHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCCCEEECCHHHHHHHHHHCCCCCCHHHH
LCDLVNYYRKGGEHHLRNQTLLTAREQEIIRYLMTGASNTEIADSLFVSEHTIKSHLYNV
HHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
FKKLNVRNRLQAVSWAKEYL
HHHHCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8817489; 8905232; 9278503 [H]