Click here to switch to the map view.

The map label for this gene is marC [H]

Identifier: 145300786

GI number: 145300786

Start: 4215412

End: 4216128

Strand: Direct

Name: marC [H]

Synonym: ASA_3927

Alternate gene names: 145300786

Gene position: 4215412-4216128 (Clockwise)

Preceding gene: 145300784

Following gene: 145300787

Centisome position: 89.64

GC content: 59.41

Gene sequence:

>717_bases
ATGTTCTTTCAAGTCGTATTTCTCGCCTTGCTGGCGCTGCTGCCCATGGTCAACCCGCCAACCACGGCCACCCTGCTATT
GGGGCTGAGCAAGGGCATGTCGCGGGAGCATGTGCGCCGCCAGGTCAACCTGGCGGCTATCTATCTGTTTTTCACCCTCT
GCATCACCTTCTTTATCGGCTCCTCCATTCTGGATCTGTTCGGGATATCCATTCCAGGCTTGCGGCTGGCAGGGGGTCTC
ATCATCGGCTTTATCGGCTTTCGCATGCTGTTCCCAGCCCCCAGTCAGACCAACGGGGTCGATATCAACCAGAGCATCGC
CTTCGTGCCACTGACCATGCCCAGCATGTGCGGGCCGGGTACCATGGCGCTGGTGATCAGCGGCGCTGCCCAGATTGCCG
AGCTGCCCGACGAGTACAACCGCCTCACCATCTACGGCGCCATGGTCACAGCGTTTGCCCTGATGAGTCTGATCAGCTGG
GGCGTATTGAAGCTGGCGGATCCGGTCTGCAAGATCCTCGGCGCTACCGGCATCGATGCCATGACCCGGATCATGGGTTT
TCTGCTGGTGTGCATGGGCATGCAATTCTGTATCAACGGCATCAAGGAAGTGGCACAGGATCCTGTCTTCCACGGCGCAC
ACTCGATACACACCACGCCTTCCTTGCCATCCCTGCCAGACACCCCTGATCAACGACAGGAGCCGCGCCACCCCTGA

Upstream 100 bases:

>100_bases
CCTTGTGTTCAGTACGGCCGACATAGGATAGCCTCCCCCTTAGGGCCAGGCGAATACCGGGCTCCAGACTGTCACCCAAT
TCCGTTATCCGAGGCTCAAG

Downstream 100 bases:

>100_bases
CTGAAAACGGTGTCAAAAAACCTCACAAATCGCCACTGATCTTGCGCCTGATCATGTTATTGATACACAAATGAGTTAGT
GTGTTTTTCATACAGATTCA

Product: multiple drug resistance protein MarC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MFFQVVFLALLALLPMVNPPTTATLLLGLSKGMSREHVRRQVNLAAIYLFFTLCITFFIGSSILDLFGISIPGLRLAGGL
IIGFIGFRMLFPAPSQTNGVDINQSIAFVPLTMPSMCGPGTMALVISGAAQIAELPDEYNRLTIYGAMVTAFALMSLISW
GVLKLADPVCKILGATGIDAMTRIMGFLLVCMGMQFCINGIKEVAQDPVFHGAHSIHTTPSLPSLPDTPDQRQEPRHP

Sequences:

>Translated_238_residues
MFFQVVFLALLALLPMVNPPTTATLLLGLSKGMSREHVRRQVNLAAIYLFFTLCITFFIGSSILDLFGISIPGLRLAGGL
IIGFIGFRMLFPAPSQTNGVDINQSIAFVPLTMPSMCGPGTMALVISGAAQIAELPDEYNRLTIYGAMVTAFALMSLISW
GVLKLADPVCKILGATGIDAMTRIMGFLLVCMGMQFCINGIKEVAQDPVFHGAHSIHTTPSLPSLPDTPDQRQEPRHP
>Mature_238_residues
MFFQVVFLALLALLPMVNPPTTATLLLGLSKGMSREHVRRQVNLAAIYLFFTLCITFFIGSSILDLFGISIPGLRLAGGL
IIGFIGFRMLFPAPSQTNGVDINQSIAFVPLTMPSMCGPGTMALVISGAAQIAELPDEYNRLTIYGAMVTAFALMSLISW
GVLKLADPVCKILGATGIDAMTRIMGFLLVCMGMQFCINGIKEVAQDPVFHGAHSIHTTPSLPSLPDTPDQRQEPRHP

Specific function: Unknown

COG id: COG2095

COG function: function code U; Multiple antibiotic transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0056 (marC) family [H]

Homologues:

Organism=Escherichia coli, GI1787809, Length=200, Percent_Identity=43.5, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1787494, Length=210, Percent_Identity=30.4761904761905, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1789842, Length=170, Percent_Identity=27.0588235294118, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002771 [H]

Pfam domain/function: PF01914 MarC [H]

EC number: NA

Molecular weight: Translated: 25654; Mature: 25654

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFQVVFLALLALLPMVNPPTTATLLLGLSKGMSREHVRRQVNLAAIYLFFTLCITFFIG
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SSILDLFGISIPGLRLAGGLIIGFIGFRMLFPAPSQTNGVDINQSIAFVPLTMPSMCGPG
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCC
TMALVISGAAQIAELPDEYNRLTIYGAMVTAFALMSLISWGVLKLADPVCKILGATGIDA
HHHHHHHHHHHHHHCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
MTRIMGFLLVCMGMQFCINGIKEVAQDPVFHGAHSIHTTPSLPSLPDTPDQRQEPRHP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFFQVVFLALLALLPMVNPPTTATLLLGLSKGMSREHVRRQVNLAAIYLFFTLCITFFIG
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SSILDLFGISIPGLRLAGGLIIGFIGFRMLFPAPSQTNGVDINQSIAFVPLTMPSMCGPG
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCC
TMALVISGAAQIAELPDEYNRLTIYGAMVTAFALMSLISWGVLKLADPVCKILGATGIDA
HHHHHHHHHHHHHHCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
MTRIMGFLLVCMGMQFCINGIKEVAQDPVFHGAHSIHTTPSLPSLPDTPDQRQEPRHP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA