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The map label for this gene is foxA [H]

Identifier: 145300744

GI number: 145300744

Start: 4169741

End: 4171783

Strand: Direct

Name: foxA [H]

Synonym: ASA_3883

Alternate gene names: 145300744

Gene position: 4169741-4171783 (Clockwise)

Preceding gene: 145300743

Following gene: 145300745

Centisome position: 88.67

GC content: 63.49

Gene sequence:

>2043_bases
ATGTACACACCGAATCACCCACGCGCCCTGCTGGGCGTTGCTCTGCTGGCCCTGAGTGCCGGCGCCCGCGCCGAAGACGA
GACCATGACGGTCGTCGGCAAACGCAGCCAGCATGAAGAGGTCGCCACCGCGACCCGCACCAACACCCCGGCCAAGCTTG
TTCCCCAGGCGATCGACAGCGTCAAGGCCAGCGAACTGACCGCCTTCGGCCAACCCACCCTGAGCGAGGCCCTGACCGGT
ATTCCCGGGGTCAACGCCAGCGGTGACACCCGCTTCGATAGCGTCAATATCCGTGGCTTCAGTGCCAGCAATGACTTCTA
TCTGGACGGCTTTCGCGATGACATGCAGTACACCCGGGATCTCGGCAACATAGAGAGGGTCGAGGTGCTCAAGGGCCCGG
CGGCGGTGCTGTACGGCCGTGGCAGCACGGGTGGCATCATCAACCGGGTCAGCAAGAAACCGCAGAAGGGGCAGGAGTCC
AGCGTCACCGCCCTGGTTGGCAGTTTCGATACCAGGCGCGTGGCCGCCGACCTCAATGCCGAGGCGGGTGAACGGGTGCA
GCTGCGCCTCAACCTGGCACAGGAAGACAAGGACAGTTTTCGCAACGACGTGACCAGCAAGCGCACCCTGCTGGCCCCCT
CCGCCAACTGGGAGATCAGCGACAAGCTGAACTGGCTGGTACAGTACGAGCGCAATGCCCACGACCGCACCCCGGATCGC
GGCATTCCCGGCGTCAATGGCCGTCCGGCCGACGTGCCGAAGGAATATGTCTACAGCGACACTCGCCGCGACTTTATCGA
CGACGTGGCGCAATCCACTCGCTCCCGCCTCTCCTGGGATCTCAACGATCAGTGGCAACTGCGCCAGCAGCTGGGCTACA
GCACCCTCGACAGCCAGTTCGACAACACCTATGTCACCAGCGTCAAAGGGGATCAGGTCACCCGTGCCCGCTGGCAGCAG
GATCTCAAGGCCAACAGCCTGATCAGCAACACAGAGGCCGAAGGCCAGCTGCAAACAGGCCCCGTTGAGCATCGCCTGCT
GATCGGGTTCGAGCAGAACTGGCAGGAGCGCACTCCCAAGCTCTACCAGAACGCCAGCCCTATCCCGGCCGGCAATCTTT
ACGACCCCGGCTCACTGCCCACCTATGATGGCGCCATGAAGTTATCCAGCGACGCCAACCACAAGGTGCGCGGTTACGGC
CTCTATCTGCAGGATCAACTCAGCCTGGGTGACTGGCATCTGGTAGGCGGCTTGCGCCGCGACGACTTCACCGTCACCAG
CCGCCGCAACGACCTCAACAAGGAAGAGACCCTTTCGGTCACCAGCCTGAGCCCACGGCTGGGGCTGGTGTGGAATCCCC
TCGAGGATCACGCCTTCTACACCTCCTACAGCAAGACCTTCACACCGGTGGGCGGGGAGCTTATCGGCATCACACCGGGG
GACAAGAACAACGCTCTGGATCCTCAGAACACCCGGCTGTATGAGGGGGGCGTGAAGAGCGACTGGCTGGATGGCCGCCT
GGCGACCACCCTCTCTCTCTATCGGTTGGAGATGTACAACAAGCGCAGCAAGGACCCGCTGGATCCCACCAAGGTGACCC
TCACCGGCCTGCAACGCACAAATGGCATAGAGCTGAGTGCCCGCGCCCAGCTGACCGACGAACTCTACCTGCGCGGCGGC
ATCGCCATCCAGGATGCCGAGCAGGTCAAGGCGGATGCGGATCTGCAGGGCAAGCGACCGATGAACGTCTCCCGCCAGAA
CGGCCAGCTGTTTGCCGGCTATGAGAGCGGCCAGCAGGGTTGGTTCGGCGAAACCGGCGTGACTGCGGTAGGCGATCGCT
TCGCCGACAACGCCAACACCACCATTTTGCCCGGCTATGCCCGCTTCGATGCCCGCGCAGGCTACCGCTGGCAGCAGTGG
GAAGCCCAGCTGAGCGCCGAGAACCTGACCGACCACGACTACTTCGTCAGCGCCACCAGTGCCTCCCAGATCCTGCCGGG
CACGCCCCGCCAGCTGAATCTGAGCGCAGCCTACCGTTTCTGA

Upstream 100 bases:

>100_bases
CAATATCATTAGCATCCTCTCAAATGAGAGAAACCAATAATTATAAATAAATCAATAAGTTCAGACCATCAGGTCGCTTC
CTCAAGAGTCAACACGCAAC

Downstream 100 bases:

>100_bases
TCTTCTTTTCATCACAGATGACCCCTGGCCAGCGATTGCTGGCCAGATTTTTATGAAGCGCAAAATATGAAACGCAAAAA
ACTCCCTCTTCACAACAACA

Product: outer membrane ferric siderophore receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 680; Mature: 680

Protein sequence:

>680_residues
MYTPNHPRALLGVALLALSAGARAEDETMTVVGKRSQHEEVATATRTNTPAKLVPQAIDSVKASELTAFGQPTLSEALTG
IPGVNASGDTRFDSVNIRGFSASNDFYLDGFRDDMQYTRDLGNIERVEVLKGPAAVLYGRGSTGGIINRVSKKPQKGQES
SVTALVGSFDTRRVAADLNAEAGERVQLRLNLAQEDKDSFRNDVTSKRTLLAPSANWEISDKLNWLVQYERNAHDRTPDR
GIPGVNGRPADVPKEYVYSDTRRDFIDDVAQSTRSRLSWDLNDQWQLRQQLGYSTLDSQFDNTYVTSVKGDQVTRARWQQ
DLKANSLISNTEAEGQLQTGPVEHRLLIGFEQNWQERTPKLYQNASPIPAGNLYDPGSLPTYDGAMKLSSDANHKVRGYG
LYLQDQLSLGDWHLVGGLRRDDFTVTSRRNDLNKEETLSVTSLSPRLGLVWNPLEDHAFYTSYSKTFTPVGGELIGITPG
DKNNALDPQNTRLYEGGVKSDWLDGRLATTLSLYRLEMYNKRSKDPLDPTKVTLTGLQRTNGIELSARAQLTDELYLRGG
IAIQDAEQVKADADLQGKRPMNVSRQNGQLFAGYESGQQGWFGETGVTAVGDRFADNANTTILPGYARFDARAGYRWQQW
EAQLSAENLTDHDYFVSATSASQILPGTPRQLNLSAAYRF

Sequences:

>Translated_680_residues
MYTPNHPRALLGVALLALSAGARAEDETMTVVGKRSQHEEVATATRTNTPAKLVPQAIDSVKASELTAFGQPTLSEALTG
IPGVNASGDTRFDSVNIRGFSASNDFYLDGFRDDMQYTRDLGNIERVEVLKGPAAVLYGRGSTGGIINRVSKKPQKGQES
SVTALVGSFDTRRVAADLNAEAGERVQLRLNLAQEDKDSFRNDVTSKRTLLAPSANWEISDKLNWLVQYERNAHDRTPDR
GIPGVNGRPADVPKEYVYSDTRRDFIDDVAQSTRSRLSWDLNDQWQLRQQLGYSTLDSQFDNTYVTSVKGDQVTRARWQQ
DLKANSLISNTEAEGQLQTGPVEHRLLIGFEQNWQERTPKLYQNASPIPAGNLYDPGSLPTYDGAMKLSSDANHKVRGYG
LYLQDQLSLGDWHLVGGLRRDDFTVTSRRNDLNKEETLSVTSLSPRLGLVWNPLEDHAFYTSYSKTFTPVGGELIGITPG
DKNNALDPQNTRLYEGGVKSDWLDGRLATTLSLYRLEMYNKRSKDPLDPTKVTLTGLQRTNGIELSARAQLTDELYLRGG
IAIQDAEQVKADADLQGKRPMNVSRQNGQLFAGYESGQQGWFGETGVTAVGDRFADNANTTILPGYARFDARAGYRWQQW
EAQLSAENLTDHDYFVSATSASQILPGTPRQLNLSAAYRF
>Mature_680_residues
MYTPNHPRALLGVALLALSAGARAEDETMTVVGKRSQHEEVATATRTNTPAKLVPQAIDSVKASELTAFGQPTLSEALTG
IPGVNASGDTRFDSVNIRGFSASNDFYLDGFRDDMQYTRDLGNIERVEVLKGPAAVLYGRGSTGGIINRVSKKPQKGQES
SVTALVGSFDTRRVAADLNAEAGERVQLRLNLAQEDKDSFRNDVTSKRTLLAPSANWEISDKLNWLVQYERNAHDRTPDR
GIPGVNGRPADVPKEYVYSDTRRDFIDDVAQSTRSRLSWDLNDQWQLRQQLGYSTLDSQFDNTYVTSVKGDQVTRARWQQ
DLKANSLISNTEAEGQLQTGPVEHRLLIGFEQNWQERTPKLYQNASPIPAGNLYDPGSLPTYDGAMKLSSDANHKVRGYG
LYLQDQLSLGDWHLVGGLRRDDFTVTSRRNDLNKEETLSVTSLSPRLGLVWNPLEDHAFYTSYSKTFTPVGGELIGITPG
DKNNALDPQNTRLYEGGVKSDWLDGRLATTLSLYRLEMYNKRSKDPLDPTKVTLTGLQRTNGIELSARAQLTDELYLRGG
IAIQDAEQVKADADLQGKRPMNVSRQNGQLFAGYESGQQGWFGETGVTAVGDRFADNANTTILPGYARFDARAGYRWQQW
EAQLSAENLTDHDYFVSATSASQILPGTPRQLNLSAAYRF

Specific function: Ferrioxamine binding and uptake, in association with the tonB protein. May play a role in intestinal colonization [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1787024, Length=682, Percent_Identity=25.5131964809384, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1786344, Length=762, Percent_Identity=25.8530183727034, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1787344, Length=752, Percent_Identity=22.8723404255319, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1790743, Length=687, Percent_Identity=22.707423580786, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 75352; Mature: 75352

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS00430 TONB_DEPENDENT_REC_1 ; PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTPNHPRALLGVALLALSAGARAEDETMTVVGKRSQHEEVATATRTNTPAKLVPQAIDS
CCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHH
VKASELTAFGQPTLSEALTGIPGVNASGDTRFDSVNIRGFSASNDFYLDGFRDDMQYTRD
HHHHHHHHCCCCHHHHHHCCCCCCCCCCCCEEEEEEEEEEECCCCEEECCCHHHHHHHHH
LGNIERVEVLKGPAAVLYGRGSTGGIINRVSKKPQKGQESSVTALVGSFDTRRVAADLNA
CCCCEEEEEECCCEEEEEECCCCCHHHHHHHCCCCCCCCCCCEEEECCCCCCEEEECCCC
EAGERVQLRLNLAQEDKDSFRNDVTSKRTLLAPSANWEISDKLNWLVQYERNAHDRTPDR
CCCCEEEEEEECCCCHHHHHHHHCCCCEEEECCCCCCEECCCEEEEEEECCCCCCCCCCC
GIPGVNGRPADVPKEYVYSDTRRDFIDDVAQSTRSRLSWDLNDQWQLRQQLGYSTLDSQF
CCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHCC
DNTYVTSVKGDQVTRARWQQDLKANSLISNTEAEGQLQTGPVEHRLLIGFEQNWQERTPK
CCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCEEEEEEECCCHHHCCCH
LYQNASPIPAGNLYDPGSLPTYDGAMKLSSDANHKVRGYGLYLQDQLSLGDWHLVGGLRR
HHCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEEEEECCCCCCEEEECCCCC
DDFTVTSRRNDLNKEETLSVTSLSPRLGLVWNPLEDHAFYTSYSKTFTPVGGELIGITPG
CCEEEECCCCCCCHHHEEEEEECCCCCCEEECCHHCCEEEECCCCEECCCCCEEEEECCC
DKNNALDPQNTRLYEGGVKSDWLDGRLATTLSLYRLEMYNKRSKDPLDPTKVTLTGLQRT
CCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCC
NGIELSARAQLTDELYLRGGIAIQDAEQVKADADLQGKRPMNVSRQNGQLFAGYESGQQG
CCEEEEEHHHCCHHHHEECCEEEECHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCC
WFGETGVTAVGDRFADNANTTILPGYARFDARAGYRWQQWEAQLSAENLTDHDYFVSATS
CCCCCCCHHHHHHHCCCCCCEEECCHHHHCCCCCCCHHHHHHHHCCCCCCCCCEEEEECC
ASQILPGTPRQLNLSAAYRF
CCCCCCCCCCEEECEEECCC
>Mature Secondary Structure
MYTPNHPRALLGVALLALSAGARAEDETMTVVGKRSQHEEVATATRTNTPAKLVPQAIDS
CCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHH
VKASELTAFGQPTLSEALTGIPGVNASGDTRFDSVNIRGFSASNDFYLDGFRDDMQYTRD
HHHHHHHHCCCCHHHHHHCCCCCCCCCCCCEEEEEEEEEEECCCCEEECCCHHHHHHHHH
LGNIERVEVLKGPAAVLYGRGSTGGIINRVSKKPQKGQESSVTALVGSFDTRRVAADLNA
CCCCEEEEEECCCEEEEEECCCCCHHHHHHHCCCCCCCCCCCEEEECCCCCCEEEECCCC
EAGERVQLRLNLAQEDKDSFRNDVTSKRTLLAPSANWEISDKLNWLVQYERNAHDRTPDR
CCCCEEEEEEECCCCHHHHHHHHCCCCEEEECCCCCCEECCCEEEEEEECCCCCCCCCCC
GIPGVNGRPADVPKEYVYSDTRRDFIDDVAQSTRSRLSWDLNDQWQLRQQLGYSTLDSQF
CCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHCC
DNTYVTSVKGDQVTRARWQQDLKANSLISNTEAEGQLQTGPVEHRLLIGFEQNWQERTPK
CCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCEEEEEEECCCHHHCCCH
LYQNASPIPAGNLYDPGSLPTYDGAMKLSSDANHKVRGYGLYLQDQLSLGDWHLVGGLRR
HHCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEEEEECCCCCCEEEECCCCC
DDFTVTSRRNDLNKEETLSVTSLSPRLGLVWNPLEDHAFYTSYSKTFTPVGGELIGITPG
CCEEEECCCCCCCHHHEEEEEECCCCCCEEECCHHCCEEEECCCCEECCCCCEEEEECCC
DKNNALDPQNTRLYEGGVKSDWLDGRLATTLSLYRLEMYNKRSKDPLDPTKVTLTGLQRT
CCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCC
NGIELSARAQLTDELYLRGGIAIQDAEQVKADADLQGKRPMNVSRQNGQLFAGYESGQQG
CCEEEEEHHHCCHHHHEECCEEEECHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCC
WFGETGVTAVGDRFADNANTTILPGYARFDARAGYRWQQWEAQLSAENLTDHDYFVSATS
CCCCCCCHHHHHHHCCCCCCEEECCHHHHCCCCCCCHHHHHHHHCCCCCCCCCEEEEECC
ASQILPGTPRQLNLSAAYRF
CCCCCCCCCCEEECEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 10103258; 7642488 [H]