Click here to switch to the map view.

The map label for this gene is fimD [H]

Identifier: 145300596

GI number: 145300596

Start: 4020533

End: 4021264

Strand: Direct

Name: fimD [H]

Synonym: ASA_3728

Alternate gene names: 145300596

Gene position: 4020533-4021264 (Clockwise)

Preceding gene: 145300595

Following gene: 145300597

Centisome position: 85.5

GC content: 52.05

Gene sequence:

>732_bases
ATGAAAAAGCTGCTCTCTTTTACCTGTCTGGCCGTACTGGGTATGACGTCACTGAACGTCAGTGCCGCAATTGTGCTGGA
TCGTACTCGCGCCGTTTATCCTGGTGGCGCCAAATCCATCAGTCTCAACATCAAAAACGAAAATCAGAAGCTGCCTTATC
TGGCGCAGGCCTGGATTGAAGATGCCCTGGGGCAGAAGATCGTTTCGCCTTTCGTGGTGCTGCCGCCAGTGCAGCGGGTG
GATGCCAATCAGAAGTCGATTGTCAGGATCGCCTCTGTGCCTGCGATCGAAACGTTGCCAAAAGATCGCGAATCTATCTA
CTACTTCAACCTGCGCGAGATCCCGCCCAAGAGCGAGAAGAGCAACGTCATGCAGATTGCCGTGCAATCCAAGATCAAGC
TCTTCTACCGCCCAGAGGCTATCCTCCCTGAGCGTGGTGCCGTCTGGCAGGATCAAGTGACGATCACCAAACAGGGCACA
ACCCTGAAGGTCAATAACCCGACCCCTTACTACGTCACCTATGTCGGTCTGGCTCATCCCAAGGGCAAAGAAAAAACATC
TATTAAAGGCTTCTCTGCCTTTATGGTGGCCCCCAAATCCGAGCTGGATGCCAAGATCCCCGAGACGTTGGGCAGTGAAT
TCATCATCAGCTATGTAAACGATTACGGCGGATATATGGATATCAAGTACCAGTGTGTCGGCAATGCCTGTAAAGCCATG
AAGAGCGAGTAA

Upstream 100 bases:

>100_bases
GAACTTTCCTGGGGTGGTGCCCGTCAGTGCAAGATAGCGGCACCGCACGAAGTAACCGATCTGTCGATGAAGACGCTCAC
TTGTAAGTAATGGGAACCCG

Downstream 100 bases:

>100_bases
GGTTATGTTACGTTCCGTTTTTTGCTCCGGTTTTTTGCTGTTTGCTGGCACAGCGCTGGCAAATGGTTATGTCATTCCTG
ATGGGGATCATGAATACAGG

Product: type I pilus chaperone protein FimD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MKKLLSFTCLAVLGMTSLNVSAAIVLDRTRAVYPGGAKSISLNIKNENQKLPYLAQAWIEDALGQKIVSPFVVLPPVQRV
DANQKSIVRIASVPAIETLPKDRESIYYFNLREIPPKSEKSNVMQIAVQSKIKLFYRPEAILPERGAVWQDQVTITKQGT
TLKVNNPTPYYVTYVGLAHPKGKEKTSIKGFSAFMVAPKSELDAKIPETLGSEFIISYVNDYGGYMDIKYQCVGNACKAM
KSE

Sequences:

>Translated_243_residues
MKKLLSFTCLAVLGMTSLNVSAAIVLDRTRAVYPGGAKSISLNIKNENQKLPYLAQAWIEDALGQKIVSPFVVLPPVQRV
DANQKSIVRIASVPAIETLPKDRESIYYFNLREIPPKSEKSNVMQIAVQSKIKLFYRPEAILPERGAVWQDQVTITKQGT
TLKVNNPTPYYVTYVGLAHPKGKEKTSIKGFSAFMVAPKSELDAKIPETLGSEFIISYVNDYGGYMDIKYQCVGNACKAM
KSE
>Mature_243_residues
MKKLLSFTCLAVLGMTSLNVSAAIVLDRTRAVYPGGAKSISLNIKNENQKLPYLAQAWIEDALGQKIVSPFVVLPPVQRV
DANQKSIVRIASVPAIETLPKDRESIYYFNLREIPPKSEKSNVMQIAVQSKIKLFYRPEAILPERGAVWQDQVTITKQGT
TLKVNNPTPYYVTYVGLAHPKGKEKTSIKGFSAFMVAPKSELDAKIPETLGSEFIISYVNDYGGYMDIKYQCVGNACKAM
KSE

Specific function: Involved in the biogenesis of the PMF fimbria [H]

COG id: COG3121

COG function: function code NU; P pilus assembly protein, chaperone PapD

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Ig-like (immunoglobulin-like) domain [H]

Homologues:

Organism=Escherichia coli, GI1788677, Length=215, Percent_Identity=46.046511627907, Blast_Score=205, Evalue=2e-54,
Organism=Escherichia coli, GI1786936, Length=230, Percent_Identity=39.1304347826087, Blast_Score=174, Evalue=5e-45,
Organism=Escherichia coli, GI87082203, Length=220, Percent_Identity=37.2727272727273, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1789532, Length=225, Percent_Identity=30.2222222222222, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1790771, Length=226, Percent_Identity=30.9734513274336, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1788428, Length=236, Percent_Identity=30.0847457627119, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1786333, Length=238, Percent_Identity=31.9327731092437, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1786743, Length=231, Percent_Identity=29.8701298701299, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1787171, Length=206, Percent_Identity=30.0970873786408, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI87081806, Length=249, Percent_Identity=24.0963855421687, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008962
- InterPro:   IPR001829
- InterPro:   IPR016148
- InterPro:   IPR018046
- InterPro:   IPR016147 [H]

Pfam domain/function: PF02753 Pili_assembly_C; PF00345 Pili_assembly_N [H]

EC number: NA

Molecular weight: Translated: 26954; Mature: 26954

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS00635 PILI_CHAPERONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLSFTCLAVLGMTSLNVSAAIVLDRTRAVYPGGAKSISLNIKNENQKLPYLAQAWIE
CCHHHHHHHHHHHCCCCCCCEEEEEEECCEEECCCCCCEEEEEECCCCCCCCHHHHHHHH
DALGQKIVSPFVVLPPVQRVDANQKSIVRIASVPAIETLPKDRESIYYFNLREIPPKSEK
HHHHHHHHCCEEECCCHHHCCCCCHHEEEEECCCCHHHCCCCCCEEEEEEEECCCCCCCC
SNVMQIAVQSKIKLFYRPEAILPERGAVWQDQVTITKQGTTLKVNNPTPYYVTYVGLAHP
CHHEEEEEECCEEEEECCCCCCCCCCCEEECCEEEEECCCEEEECCCCCEEEEEEEEECC
KGKEKTSIKGFSAFMVAPKSELDAKIPETLGSEFIISYVNDYGGYMDIKYQCVGNACKAM
CCCCCCCCCCEEEEEECCHHHCCCCCHHHHCHHHHHHHHHHCCCEEEEEEEECCHHHHHH
KSE
CCC
>Mature Secondary Structure
MKKLLSFTCLAVLGMTSLNVSAAIVLDRTRAVYPGGAKSISLNIKNENQKLPYLAQAWIE
CCHHHHHHHHHHHCCCCCCCEEEEEEECCEEECCCCCCEEEEEECCCCCCCCHHHHHHHH
DALGQKIVSPFVVLPPVQRVDANQKSIVRIASVPAIETLPKDRESIYYFNLREIPPKSEK
HHHHHHHHCCEEECCCHHHCCCCCHHEEEEECCCCHHHCCCCCCEEEEEEEECCCCCCCC
SNVMQIAVQSKIKLFYRPEAILPERGAVWQDQVTITKQGTTLKVNNPTPYYVTYVGLAHP
CHHEEEEEECCEEEEECCCCCCCCCCCEEECCEEEEECCCEEEECCCCCEEEEEEEEECC
KGKEKTSIKGFSAFMVAPKSELDAKIPETLGSEFIISYVNDYGGYMDIKYQCVGNACKAM
CCCCCCCCCCEEEEEECCHHHCCCCCHHHHCHHHHHHHHHHCCCEEEEEEEECCHHHHHH
KSE
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7959033 [H]