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The map label for this gene is xerC [H]

Identifier: 145300550

GI number: 145300550

Start: 3968604

End: 3969572

Strand: Direct

Name: xerC [H]

Synonym: ASA_3682

Alternate gene names: 145300550

Gene position: 3968604-3969572 (Clockwise)

Preceding gene: 145300549

Following gene: 145300551

Centisome position: 84.4

GC content: 63.47

Gene sequence:

>969_bases
ATGGCTAGGGAACCGGCCAAAGCGTCTGCCCCTGCCGCCGAGCCTCTGCCAGCCTCTCTGGCCGATGAGCTGGCGGCCTT
TATCGAATACCTGAGGGTCGAGCGCCAGCTCAGCCCTCACACTCGCAGCAACTATGAATCCCATCTGCAGGCCATGGCCG
CCGAGCTGGTCAGGCTGGGTGTAAGCGACTGGGCCCGGCTCGAGGCGAGCCAGGTGCGCAGTCTGGTGACCCGGATGCAC
AAGGCCGGGCTCGCTCCCCGCTCCCTTTCTACCAAGATCTCCGCCTTGCGCAGTTTCTGCGACTGGCAGGTGCGCCAGGG
ACGGCTCACCGCCAACCCGGCCCGCGGCATAGTGACCCCCAAGCAGGGGCGACCGCTGCCGAAAAATCTGGATGTGGACG
AGATGTACCAGTTGCTCAACATCACAGACGAGCAGGATCCCCTGGCGGTACGGGATCGGGCCATCATGGAGCTGATGTAC
TCTTCCGGCCTGCGGCTGGCCGAGCTGGTGGGGCTCAATCTGGGTGACATCAAGCTCGATGACCGTCAGCTCAAGGTGAC
CGGCAAGGGCTCGCGGGAGCGGGTGCTGCCCATGGGAAGAATGGCGGTGGAGTGGCTGCACAAGTGGCTCAAGGTACGCC
CTCTGCTGGCGGGGGACGAGGCCGACGCCTTGTTCGTCTCCAAGCGCAAACAGCGGCTGTCGGCCCGTTCCGTACAGGAG
CGGCTCGATGGCTGGGGAAACAAGCAGGCGCTCAATGCCCACGTCCATCCCCACAAGCTGCGCCACAGTTTCGCCACTCA
CATGCTGGAGTCCTCCGGCGATCTGCGTGCCGTGCAGGAGCTGCTGGGTCATGCGGATCTCTCCACTACCCAGATCTATA
CCCATCTCGATTTTCAGCATCTGGCCAAGGTCTATGACAATGCCCACCCAAGAGCAAAGCGGGATCCTGCCACGCCGGAA
GATGAGTGA

Upstream 100 bases:

>100_bases
TTTGCCAGTTCCGATCCCAGCCACTTCAGCCCCCATAACGACACCCTGCTGCTGGGTCAGCTGGGTCGCTTGTTGCAGTT
GCGTCTGCCTGAACTGACCC

Downstream 100 bases:

>100_bases
CCTTTACCTCTGTGAAGGAGTGTCTGGGGTTATCTGAGCATCCAAACCGCCAGGGTAGCCAGATATGCCGGAAGATGAAC
AAGGGGGCCTGATTATTTCG

Product: tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MAREPAKASAPAAEPLPASLADELAAFIEYLRVERQLSPHTRSNYESHLQAMAAELVRLGVSDWARLEASQVRSLVTRMH
KAGLAPRSLSTKISALRSFCDWQVRQGRLTANPARGIVTPKQGRPLPKNLDVDEMYQLLNITDEQDPLAVRDRAIMELMY
SSGLRLAELVGLNLGDIKLDDRQLKVTGKGSRERVLPMGRMAVEWLHKWLKVRPLLAGDEADALFVSKRKQRLSARSVQE
RLDGWGNKQALNAHVHPHKLRHSFATHMLESSGDLRAVQELLGHADLSTTQIYTHLDFQHLAKVYDNAHPRAKRDPATPE
DE

Sequences:

>Translated_322_residues
MAREPAKASAPAAEPLPASLADELAAFIEYLRVERQLSPHTRSNYESHLQAMAAELVRLGVSDWARLEASQVRSLVTRMH
KAGLAPRSLSTKISALRSFCDWQVRQGRLTANPARGIVTPKQGRPLPKNLDVDEMYQLLNITDEQDPLAVRDRAIMELMY
SSGLRLAELVGLNLGDIKLDDRQLKVTGKGSRERVLPMGRMAVEWLHKWLKVRPLLAGDEADALFVSKRKQRLSARSVQE
RLDGWGNKQALNAHVHPHKLRHSFATHMLESSGDLRAVQELLGHADLSTTQIYTHLDFQHLAKVYDNAHPRAKRDPATPE
DE
>Mature_321_residues
AREPAKASAPAAEPLPASLADELAAFIEYLRVERQLSPHTRSNYESHLQAMAAELVRLGVSDWARLEASQVRSLVTRMHK
AGLAPRSLSTKISALRSFCDWQVRQGRLTANPARGIVTPKQGRPLPKNLDVDEMYQLLNITDEQDPLAVRDRAIMELMYS
SGLRLAELVGLNLGDIKLDDRQLKVTGKGSRERVLPMGRMAVEWLHKWLKVRPLLAGDEADALFVSKRKQRLSARSVQER
LDGWGNKQALNAHVHPHKLRHSFATHMLESSGDLRAVQELLGHADLSTTQIYTHLDFQHLAKVYDNAHPRAKRDPATPED
E

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from xerD binding sites by a short central region, forming

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=295, Percent_Identity=58.6440677966102, Blast_Score=342, Evalue=2e-95,
Organism=Escherichia coli, GI1789261, Length=289, Percent_Identity=35.9861591695502, Blast_Score=175, Evalue=3e-45,
Organism=Escherichia coli, GI1790768, Length=148, Percent_Identity=29.7297297297297, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790767, Length=168, Percent_Identity=26.1904761904762, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 36164; Mature: 36033

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAREPAKASAPAAEPLPASLADELAAFIEYLRVERQLSPHTRSNYESHLQAMAAELVRLG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHC
VSDWARLEASQVRSLVTRMHKAGLAPRSLSTKISALRSFCDWQVRQGRLTANPARGIVTP
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
KQGRPLPKNLDVDEMYQLLNITDEQDPLAVRDRAIMELMYSSGLRLAELVGLNLGDIKLD
CCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEEEC
DRQLKVTGKGSRERVLPMGRMAVEWLHKWLKVRPLLAGDEADALFVSKRKQRLSARSVQE
CCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RLDGWGNKQALNAHVHPHKLRHSFATHMLESSGDLRAVQELLGHADLSTTQIYTHLDFQH
HHCCCCCCCCEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHCCHHH
LAKVYDNAHPRAKRDPATPEDE
HHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AREPAKASAPAAEPLPASLADELAAFIEYLRVERQLSPHTRSNYESHLQAMAAELVRLG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHC
VSDWARLEASQVRSLVTRMHKAGLAPRSLSTKISALRSFCDWQVRQGRLTANPARGIVTP
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
KQGRPLPKNLDVDEMYQLLNITDEQDPLAVRDRAIMELMYSSGLRLAELVGLNLGDIKLD
CCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEEEC
DRQLKVTGKGSRERVLPMGRMAVEWLHKWLKVRPLLAGDEADALFVSKRKQRLSARSVQE
CCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RLDGWGNKQALNAHVHPHKLRHSFATHMLESSGDLRAVQELLGHADLSTTQIYTHLDFQH
HHCCCCCCCCEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHCCHHH
LAKVYDNAHPRAKRDPATPEDE
HHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9675854 [H]