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The map label for this gene is mppA [H]

Identifier: 145300493

GI number: 145300493

Start: 3916251

End: 3917855

Strand: Direct

Name: mppA [H]

Synonym: ASA_3625

Alternate gene names: 145300493

Gene position: 3916251-3917855 (Clockwise)

Preceding gene: 145300491

Following gene: 145300494

Centisome position: 83.28

GC content: 61.31

Gene sequence:

>1605_bases
ATGAAAGGATGGAGTCCCTTGCTGGCCCTGCTGGGTTGTGCCTGTGTCCAGGCCGCCGATGTTCCGCCCCGCACCCAACT
CGCCGCCGAACAGGCCGTCGTGCGTCACCTGAAAGATGAACCGGCAAGCCTGAGCCCGCTCAAGCTGGTCGGCCTGCCCG
AACTGCAGGTATTGCGAGACCTCTACGAGGGACTGCTGACCCAGGGACCGGATGGCAAGGTGCTGCCCGGCGTCGCGACG
CGGTGGGACAACAAGGACAATCAGCAGTTTACCTTCCATTTGCGACCGGATGCACGCTGGTCCAACGGTGACAAGGTCAA
GGCTGCCGACTTCGTCTACGGCTGGCGCAAGCTGGTTGATCCAAAGGAGGCCGCCACCTTCGCCTGGTTTGCCCAGCTGG
CTCACTTCACCAAGGTGGACGAGATAGTGGCTGGCAAGCTGCCGCCCGAGGCGCTCGGGGTAAAAGCCCTCGACGAGCAC
ACGCTGCAGGTGACCCTCTCCCAGCCTGTGCCCTATTTCCTGAGCCTGCTTACCCACCCCAGTCTGTCACCCCTGCATCA
GGCCAGCATGGAGCAATACGGCAACCAGTGGACCCAGCCGGGCAAGCTGGTCGGCAACGGCGCCTTCGTGCTGAGCCAAC
GGGTGGTGAACGAGAAGCTGGAGCTGGCCCCCAATCCCCATTATTGGGACAGGGCTCATACAGTGCTGACCAAGGTCACC
TTCGTCCCCATCAACCAGGAAACCGCCGCCACCAATCGCTACTTGGCAGGGGATCTGCACATCACGGAATCCTTCCCCAA
GGAGCAGTATCACAAGCTGATGCAGCAGATCCCGGGTGAGGTCCATACCCCGGATCAACTCGGCACCTACTACTACGCCT
TCAATACCCAGCTGCCACCGCTGAACGATGTGCGGGTGCGCAAGGCGCTCTCCTACACCATCGACCGCGGCCTCATTGCC
GCCAAGGTACTGGGCACTGGCGAGAAACCGGCTTATCGCTTCACGCCGGATGTGACGGCCGATTTTGAACCCAAGGCCAA
CCTGCTCTCCAGCACCAGCCAGCAAGATCTCGATGCCAGGGCCAGAGTATTGCTGCAAGAGGCGGGCTATGGCCCGGCCA
AGCCGCTCAAGCTGACCCTGCTTTACAACACCGCCGAAATCCACAAGAAGATGGCGCTGGCCATCGCCAACCTGTGGAAA
CAGAAACTGGGGGCGCAAGTCGAGCTCACCAATCAGGAGTGGAAGACCTATCTCGACAGCCGCCAGAGCGGTCAGTTCGA
GGTGATCCGCTCCTCCTGGGTGGCTGATTACAACGATCCTTCCGCCTTCCTCGGCCTGTGGGGCTCCCGGCACAGTGGCA
ACATGGCCCGCTTTGCCAACGCACGCTATGACGAGATCCTGACTCAAGCGGCCAAGAGCCGGGATCCCGGTGAGCGCGCC
CGCCTGTTCGACGAAGCCGAGTCCATCTTGCAAGATGAGGCGCCGATCGCCCCCATCTATCAGTACACCAATGCACGGCT
GATCAAACCCTGGCTCAAGGGGTATCCCATCAACAACCCGGAAGACGTGGCCTATAGCCGCCAGCTCTACCTCATCAAGC
ACTGA

Upstream 100 bases:

>100_bases
GGCGGTCTGACCAGCAAAGGGGATATCATGATTTCCCGTCTGCCGGCGATCATTTCTCGCCGAGTTTTCTCCCCGCTTCA
CACTATTTGAAGGATTAACC

Downstream 100 bases:

>100_bases
TCATGTGGGGGCCAGCCTGACTGGCCCCCATTCAGGGCTGTTCATGCTCACGTTTTAGGCATAAAATGCCGCCCTTTCCA
TCAACCTCCACTCTCTTATC

Product: periplasmic murein peptide-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 534; Mature: 534

Protein sequence:

>534_residues
MKGWSPLLALLGCACVQAADVPPRTQLAAEQAVVRHLKDEPASLSPLKLVGLPELQVLRDLYEGLLTQGPDGKVLPGVAT
RWDNKDNQQFTFHLRPDARWSNGDKVKAADFVYGWRKLVDPKEAATFAWFAQLAHFTKVDEIVAGKLPPEALGVKALDEH
TLQVTLSQPVPYFLSLLTHPSLSPLHQASMEQYGNQWTQPGKLVGNGAFVLSQRVVNEKLELAPNPHYWDRAHTVLTKVT
FVPINQETAATNRYLAGDLHITESFPKEQYHKLMQQIPGEVHTPDQLGTYYYAFNTQLPPLNDVRVRKALSYTIDRGLIA
AKVLGTGEKPAYRFTPDVTADFEPKANLLSSTSQQDLDARARVLLQEAGYGPAKPLKLTLLYNTAEIHKKMALAIANLWK
QKLGAQVELTNQEWKTYLDSRQSGQFEVIRSSWVADYNDPSAFLGLWGSRHSGNMARFANARYDEILTQAAKSRDPGERA
RLFDEAESILQDEAPIAPIYQYTNARLIKPWLKGYPINNPEDVAYSRQLYLIKH

Sequences:

>Translated_534_residues
MKGWSPLLALLGCACVQAADVPPRTQLAAEQAVVRHLKDEPASLSPLKLVGLPELQVLRDLYEGLLTQGPDGKVLPGVAT
RWDNKDNQQFTFHLRPDARWSNGDKVKAADFVYGWRKLVDPKEAATFAWFAQLAHFTKVDEIVAGKLPPEALGVKALDEH
TLQVTLSQPVPYFLSLLTHPSLSPLHQASMEQYGNQWTQPGKLVGNGAFVLSQRVVNEKLELAPNPHYWDRAHTVLTKVT
FVPINQETAATNRYLAGDLHITESFPKEQYHKLMQQIPGEVHTPDQLGTYYYAFNTQLPPLNDVRVRKALSYTIDRGLIA
AKVLGTGEKPAYRFTPDVTADFEPKANLLSSTSQQDLDARARVLLQEAGYGPAKPLKLTLLYNTAEIHKKMALAIANLWK
QKLGAQVELTNQEWKTYLDSRQSGQFEVIRSSWVADYNDPSAFLGLWGSRHSGNMARFANARYDEILTQAAKSRDPGERA
RLFDEAESILQDEAPIAPIYQYTNARLIKPWLKGYPINNPEDVAYSRQLYLIKH
>Mature_534_residues
MKGWSPLLALLGCACVQAADVPPRTQLAAEQAVVRHLKDEPASLSPLKLVGLPELQVLRDLYEGLLTQGPDGKVLPGVAT
RWDNKDNQQFTFHLRPDARWSNGDKVKAADFVYGWRKLVDPKEAATFAWFAQLAHFTKVDEIVAGKLPPEALGVKALDEH
TLQVTLSQPVPYFLSLLTHPSLSPLHQASMEQYGNQWTQPGKLVGNGAFVLSQRVVNEKLELAPNPHYWDRAHTVLTKVT
FVPINQETAATNRYLAGDLHITESFPKEQYHKLMQQIPGEVHTPDQLGTYYYAFNTQLPPLNDVRVRKALSYTIDRGLIA
AKVLGTGEKPAYRFTPDVTADFEPKANLLSSTSQQDLDARARVLLQEAGYGPAKPLKLTLLYNTAEIHKKMALAIANLWK
QKLGAQVELTNQEWKTYLDSRQSGQFEVIRSSWVADYNDPSAFLGLWGSRHSGNMARFANARYDEILTQAAKSRDPGERA
RLFDEAESILQDEAPIAPIYQYTNARLIKPWLKGYPINNPEDVAYSRQLYLIKH

Specific function: Essential for the uptake of the murein peptide L-alanyl- gamma-D-glutamyl-meso-diaminopimelate. Also transports some alpha- linked peptides such as Pro-Phe-Lys with low affinity. The transport is effected by the oligopeptide permease system [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI87081878, Length=517, Percent_Identity=60.1547388781431, Blast_Score=661, Evalue=0.0,
Organism=Escherichia coli, GI1787495, Length=529, Percent_Identity=47.069943289225, Blast_Score=509, Evalue=1e-145,
Organism=Escherichia coli, GI1789397, Length=536, Percent_Identity=41.4179104477612, Blast_Score=412, Evalue=1e-116,
Organism=Escherichia coli, GI1787762, Length=527, Percent_Identity=24.4781783681214, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1789887, Length=480, Percent_Identity=27.2916666666667, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1789966, Length=482, Percent_Identity=22.6141078838174, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1787052, Length=455, Percent_Identity=23.0769230769231, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1787551, Length=533, Percent_Identity=24.390243902439, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 59913; Mature: 59913

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGWSPLLALLGCACVQAADVPPRTQLAAEQAVVRHLKDEPASLSPLKLVGLPELQVLRD
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHH
LYEGLLTQGPDGKVLPGVATRWDNKDNQQFTFHLRPDARWSNGDKVKAADFVYGWRKLVD
HHHHHHCCCCCCCCCCCHHHCCCCCCCCEEEEEECCCCCCCCCCCEEHHHHHHHHHHHCC
PKEAATFAWFAQLAHFTKVDEIVAGKLPPEALGVKALDEHTLQVTLSQPVPYFLSLLTHP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHCCCEEEEEECCCHHHHHHHHCCC
SLSPLHQASMEQYGNQWTQPGKLVGNGAFVLSQRVVNEKLELAPNPHYWDRAHTVLTKVT
CCCHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHEEE
FVPINQETAATNRYLAGDLHITESFPKEQYHKLMQQIPGEVHTPDQLGTYYYAFNTQLPP
EEECCCCHHHCCCEEECEEEECCCCCHHHHHHHHHHCCCCCCCCHHHCCEEEEEECCCCC
LNDVRVRKALSYTIDRGLIAAKVLGTGEKPAYRFTPDVTADFEPKANLLSSTSQQDLDAR
CCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCEEECCCCCCCCCCCHHHHHCCCHHHHHHH
ARVLLQEAGYGPAKPLKLTLLYNTAEIHKKMALAIANLWKQKLGAQVELTNQEWKTYLDS
HHHHHHHCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHC
RQSGQFEVIRSSWVADYNDPSAFLGLWGSRHSGNMARFANARYDEILTQAAKSRDPGERA
CCCCCEEEEHHHHCCCCCCCHHHHCCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCHHHH
RLFDEAESILQDEAPIAPIYQYTNARLIKPWLKGYPINNPEDVAYSRQLYLIKH
HHHHHHHHHHHCCCCCCHHHHHCCCEEECHHHCCCCCCCCHHHCCCCEEEEEEC
>Mature Secondary Structure
MKGWSPLLALLGCACVQAADVPPRTQLAAEQAVVRHLKDEPASLSPLKLVGLPELQVLRD
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHH
LYEGLLTQGPDGKVLPGVATRWDNKDNQQFTFHLRPDARWSNGDKVKAADFVYGWRKLVD
HHHHHHCCCCCCCCCCCHHHCCCCCCCCEEEEEECCCCCCCCCCCEEHHHHHHHHHHHCC
PKEAATFAWFAQLAHFTKVDEIVAGKLPPEALGVKALDEHTLQVTLSQPVPYFLSLLTHP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHCCCEEEEEECCCHHHHHHHHCCC
SLSPLHQASMEQYGNQWTQPGKLVGNGAFVLSQRVVNEKLELAPNPHYWDRAHTVLTKVT
CCCHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHEEE
FVPINQETAATNRYLAGDLHITESFPKEQYHKLMQQIPGEVHTPDQLGTYYYAFNTQLPP
EEECCCCHHHCCCEEECEEEECCCCCHHHHHHHHHHCCCCCCCCHHHCCEEEEEECCCCC
LNDVRVRKALSYTIDRGLIAAKVLGTGEKPAYRFTPDVTADFEPKANLLSSTSQQDLDAR
CCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCEEECCCCCCCCCCCHHHHHCCCHHHHHHH
ARVLLQEAGYGPAKPLKLTLLYNTAEIHKKMALAIANLWKQKLGAQVELTNQEWKTYLDS
HHHHHHHCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHC
RQSGQFEVIRSSWVADYNDPSAFLGLWGSRHSGNMARFANARYDEILTQAAKSRDPGERA
CCCCCEEEEHHHHCCCCCCCHHHHCCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCHHHH
RLFDEAESILQDEAPIAPIYQYTNARLIKPWLKGYPINNPEDVAYSRQLYLIKH
HHHHHHHHHHHCCCCCCHHHHHCCCEEECHHHCCCCCCCCHHHCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9495761; 9097039; 9278503 [H]