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The map label for this gene is cat [H]

Identifier: 145300491

GI number: 145300491

Start: 3914652

End: 3915314

Strand: Direct

Name: cat [H]

Synonym: ASA_3623

Alternate gene names: 145300491

Gene position: 3914652-3915314 (Clockwise)

Preceding gene: 145300489

Following gene: 145300493

Centisome position: 83.25

GC content: 62.44

Gene sequence:

>663_bases
ATGAAGCACTGCCAACACTGGTCGCAGGTCGAGTACCTGCATCTGACGGTGACCAATCCCAATATCAGCCTCAAGGGGCA
GCACAGCTACTACTCGGGGGCCTGGGACGGTCCTTTTGAAGAGGAGGCCGTGCGCTATCTGCACGGTGACAGCTGGAGCC
GCTCACCCGACACCGGCTGGGAGCCGCTCTGGCACATAGACAGGCTCCATATCGGCGACTATGTGCAAATCGCCGCGGGC
GTGAAGATCATCATGGGAGGCAACCACACCCACAACCCGGCGTTTATCAGCACCTATCCGTTTGCCGATCCGGATGCCCT
CAAGCGCAGCTACCGCCCCGCCGGCGATACCCGTATCGGCAACGATGTCTGGATCGGGATGGACGCCATGATAATGCCGG
GGGTCACTATCGGGGATGGCGCCATTATCGCCGCCCGAAGCCTGGTGACACAGGACGTGCCACCTTACTGCATGGTGGCG
GGTGCGCCCGCCAGGGTGATCCGCCAGCGCTTTGCTGTGCAAGAAACAACACGGCTGCAAGCACTGGCCTGGTGGGACTG
GCCGGATGAGCAGGTGCAAGCCCTGCTGCCGCTGATCCAGCAAGGAGAGGTGGCGCTGCTGGAACAGGCCGCCGCTCGCT
GGCACTCAGCCGAACAGGAGTAA

Upstream 100 bases:

>100_bases
GGCTGCTCGACACTGTGCGTGCCCCGCCTGCTGGTCTGGATCTATTAGCTGCGCTCCTCGCGCCATTTATCCCTTTATCC
ATTGAACGAGGAACACAGCC

Downstream 100 bases:

>100_bases
AAACACGAGTACGGGGCGCCCCGTACTCGACCTGCTGTTTCCCTGATTCAGCTGCCGCTGCGTGACTGATTGACCCGACA
CTGCTTGCCGGGATAACCGG

Product: acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MKHCQHWSQVEYLHLTVTNPNISLKGQHSYYSGAWDGPFEEEAVRYLHGDSWSRSPDTGWEPLWHIDRLHIGDYVQIAAG
VKIIMGGNHTHNPAFISTYPFADPDALKRSYRPAGDTRIGNDVWIGMDAMIMPGVTIGDGAIIAARSLVTQDVPPYCMVA
GAPARVIRQRFAVQETTRLQALAWWDWPDEQVQALLPLIQQGEVALLEQAAARWHSAEQE

Sequences:

>Translated_220_residues
MKHCQHWSQVEYLHLTVTNPNISLKGQHSYYSGAWDGPFEEEAVRYLHGDSWSRSPDTGWEPLWHIDRLHIGDYVQIAAG
VKIIMGGNHTHNPAFISTYPFADPDALKRSYRPAGDTRIGNDVWIGMDAMIMPGVTIGDGAIIAARSLVTQDVPPYCMVA
GAPARVIRQRFAVQETTRLQALAWWDWPDEQVQALLPLIQQGEVALLEQAAARWHSAEQE
>Mature_220_residues
MKHCQHWSQVEYLHLTVTNPNISLKGQHSYYSGAWDGPFEEEAVRYLHGDSWSRSPDTGWEPLWHIDRLHIGDYVQIAAG
VKIIMGGNHTHNPAFISTYPFADPDALKRSYRPAGDTRIGNDVWIGMDAMIMPGVTIGDGAIIAARSLVTQDVPPYCMVA
GAPARVIRQRFAVQETTRLQALAWWDWPDEQVQALLPLIQQGEVALLEQAAARWHSAEQE

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786537, Length=99, Percent_Identity=40.4040404040404, Blast_Score=70, Evalue=8e-14,
Organism=Escherichia coli, GI1786664, Length=101, Percent_Identity=39.6039603960396, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 24709; Mature: 24709

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHCQHWSQVEYLHLTVTNPNISLKGQHSYYSGAWDGPFEEEAVRYLHGDSWSRSPDTGW
CCCCCCCCCEEEEEEEEECCCEEEEECCCEECCCCCCCCHHHHHHHHCCCCCCCCCCCCC
EPLWHIDRLHIGDYVQIAAGVKIIMGGNHTHNPAFISTYPFADPDALKRSYRPAGDTRIG
CCHHEECEECCCCEEEEECCEEEEECCCCCCCCEEEEECCCCCHHHHHHCCCCCCCCCCC
NDVWIGMDAMIMPGVTIGDGAIIAARSLVTQDVPPYCMVAGAPARVIRQRFAVQETTRLQ
CEEEECCCHHHCCCEEECCCHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHEE
ALAWWDWPDEQVQALLPLIQQGEVALLEQAAARWHSAEQE
EEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKHCQHWSQVEYLHLTVTNPNISLKGQHSYYSGAWDGPFEEEAVRYLHGDSWSRSPDTGW
CCCCCCCCCEEEEEEEEECCCEEEEECCCEECCCCCCCCHHHHHHHHCCCCCCCCCCCCC
EPLWHIDRLHIGDYVQIAAGVKIIMGGNHTHNPAFISTYPFADPDALKRSYRPAGDTRIG
CCHHEECEECCCCEEEEECCEEEEECCCCCCCCEEEEECCCCCHHHHHHCCCCCCCCCCC
NDVWIGMDAMIMPGVTIGDGAIIAARSLVTQDVPPYCMVAGAPARVIRQRFAVQETTRLQ
CEEEECCCHHHCCCEEECCCHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHEE
ALAWWDWPDEQVQALLPLIQQGEVALLEQAAARWHSAEQE
EEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2013403; 11743193; 11743194 [H]