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The map label for this gene is nahR [H]

Identifier: 145300485

GI number: 145300485

Start: 3910078

End: 3910989

Strand: Direct

Name: nahR [H]

Synonym: ASA_3617

Alternate gene names: 145300485

Gene position: 3910078-3910989 (Clockwise)

Preceding gene: 145300482

Following gene: 145300489

Centisome position: 83.15

GC content: 62.72

Gene sequence:

>912_bases
ATGAAACTGCACCAGCTCGACCTCAATCTGCTGCTCGCCTTTGACGCCCTGATGACACAGGGCAGCGTCACCCGCGCCGC
CGAAGCGCTGTTTATCAGCCAGCCTGCCATGAGCCACGCCCTCGGCCGGCTGCGCACCTTTTTTGGCGACCCGCTGCTGG
TGCGAACCCCGCAAGGCATGCTGCCCACTCCCCGCGCCCAGCGACTGCATCTGGGGGTACAGCAGGCGCTGCGGCTGCTG
GAGCAACAACTGAGCGACGAGGAGGTGTTCGAACCGAGCCAGTCCAAACGGCGCTTCGTGCTCTGTACCACTGACTATGT
GGAGTGCGTGCTGATCCCGCCGCTTATGCAGCGCCTCAAGAAGCTGGCACCCGGCGTCACCATAGAGATCCGCATACTGC
GCGACACGCTGCCGGAAGCCGAGCTGGCAAGCGGCGAGATCGATCTGGTGCTGGGGTTTGACGAATACATGCAGGTGCCG
AGGTATCTGGGCAAGGAGACCTGGCTCACCGAGCCCCTGGCCGGTCTGGTGCGCGCCACCCTAGAGCTGGAGGAGGAGCG
GATCACCTTGCAGCAGCTTATCGAGATGCCCCATGTGTTCCACTCGCCGCTGGGCACCTCGGAGGCGAGTCTGGATCGCT
ACCTCAGCACTCAGGGCCACAGCCGCACCATCTCGGTCAACAGCCAGAGCTATATGTCGGCAGCGACCATCGTCAGCCAG
AGCGACCACCTGCTGGTGCTGCCCAGCATGGTGGCCGAACTGCTCGCCAACCATTGGCCGCTGAAAAGCCTGCCCCTGCC
TGCGGATGTACCGGATTACCACCTCAACTGCGTCTGGCACCCGGTGCATGCACAGCAACCCGCACTGATATGGCTGAAAG
ACCTGATGAAGGAACTGGTGAATCAGCCATAA

Upstream 100 bases:

>100_bases
CCCGGGAAAAAATGAGTGTGGCCGCAGTGTAAGAAGTTGCGCTCACATCCATCAAATGAATAGGATGGATTGTCCCATAA
ACAAGGCAAATAATCCCTCC

Downstream 100 bases:

>100_bases
ACAGCAGGCTTGCAAATGGTGTTGGGGAGATTGGCGTAGCGGGAAGGAGTTGAACGGGCGCCTGGCAGGCGGTGGGAAGC
AAGGCATTCGAGGAGAAGCA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MKLHQLDLNLLLAFDALMTQGSVTRAAEALFISQPAMSHALGRLRTFFGDPLLVRTPQGMLPTPRAQRLHLGVQQALRLL
EQQLSDEEVFEPSQSKRRFVLCTTDYVECVLIPPLMQRLKKLAPGVTIEIRILRDTLPEAELASGEIDLVLGFDEYMQVP
RYLGKETWLTEPLAGLVRATLELEEERITLQQLIEMPHVFHSPLGTSEASLDRYLSTQGHSRTISVNSQSYMSAATIVSQ
SDHLLVLPSMVAELLANHWPLKSLPLPADVPDYHLNCVWHPVHAQQPALIWLKDLMKELVNQP

Sequences:

>Translated_303_residues
MKLHQLDLNLLLAFDALMTQGSVTRAAEALFISQPAMSHALGRLRTFFGDPLLVRTPQGMLPTPRAQRLHLGVQQALRLL
EQQLSDEEVFEPSQSKRRFVLCTTDYVECVLIPPLMQRLKKLAPGVTIEIRILRDTLPEAELASGEIDLVLGFDEYMQVP
RYLGKETWLTEPLAGLVRATLELEEERITLQQLIEMPHVFHSPLGTSEASLDRYLSTQGHSRTISVNSQSYMSAATIVSQ
SDHLLVLPSMVAELLANHWPLKSLPLPADVPDYHLNCVWHPVHAQQPALIWLKDLMKELVNQP
>Mature_303_residues
MKLHQLDLNLLLAFDALMTQGSVTRAAEALFISQPAMSHALGRLRTFFGDPLLVRTPQGMLPTPRAQRLHLGVQQALRLL
EQQLSDEEVFEPSQSKRRFVLCTTDYVECVLIPPLMQRLKKLAPGVTIEIRILRDTLPEAELASGEIDLVLGFDEYMQVP
RYLGKETWLTEPLAGLVRATLELEEERITLQQLIEMPHVFHSPLGTSEASLDRYLSTQGHSRTISVNSQSYMSAATIVSQ
SDHLLVLPSMVAELLANHWPLKSLPLPADVPDYHLNCVWHPVHAQQPALIWLKDLMKELVNQP

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=305, Percent_Identity=27.8688524590164, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI87081766, Length=269, Percent_Identity=27.1375464684015, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786820, Length=141, Percent_Identity=34.0425531914894, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1790147, Length=309, Percent_Identity=26.2135922330097, Blast_Score=75, Evalue=8e-15,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34141; Mature: 34141

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLHQLDLNLLLAFDALMTQGSVTRAAEALFISQPAMSHALGRLRTFFGDPLLVRTPQGM
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCCCC
LPTPRAQRLHLGVQQALRLLEQQLSDEEVFEPSQSKRRFVLCTTDYVECVLIPPLMQRLK
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEEEECCHHHHEEHHHHHHHHH
KLAPGVTIEIRILRDTLPEAELASGEIDLVLGFDEYMQVPRYLGKETWLTEPLAGLVRAT
HHCCCCEEEEEEECCCCCCCHHCCCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHH
LELEEERITLQQLIEMPHVFHSPLGTSEASLDRYLSTQGHSRTISVNSQSYMSAATIVSQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHCC
SDHLLVLPSMVAELLANHWPLKSLPLPADVPDYHLNCVWHPVHAQQPALIWLKDLMKELV
CCCEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHH
NQP
CCC
>Mature Secondary Structure
MKLHQLDLNLLLAFDALMTQGSVTRAAEALFISQPAMSHALGRLRTFFGDPLLVRTPQGM
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCCCC
LPTPRAQRLHLGVQQALRLLEQQLSDEEVFEPSQSKRRFVLCTTDYVECVLIPPLMQRLK
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEEEECCHHHHEEHHHHHHHHH
KLAPGVTIEIRILRDTLPEAELASGEIDLVLGFDEYMQVPRYLGKETWLTEPLAGLVRAT
HHCCCCEEEEEEECCCCCCCHHCCCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHH
LELEEERITLQQLIEMPHVFHSPLGTSEASLDRYLSTQGHSRTISVNSQSYMSAATIVSQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHCC
SDHLLVLPSMVAELLANHWPLKSLPLPADVPDYHLNCVWHPVHAQQPALIWLKDLMKELV
CCCEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHH
NQP
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]