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The map label for this gene is yafC [H]

Identifier: 145300477

GI number: 145300477

Start: 3900859

End: 3901728

Strand: Direct

Name: yafC [H]

Synonym: ASA_3609

Alternate gene names: 145300477

Gene position: 3900859-3901728 (Clockwise)

Preceding gene: 145300475

Following gene: 145300478

Centisome position: 82.95

GC content: 63.45

Gene sequence:

>870_bases
ATGATCAACTGGGATGACGCGCGTTTTTTTCTGGCATTGGCAAGACAGGGCACACTGCGTGGCGCGGCCGGGGTACTGGG
GGTCGATCAGGCTACCGTCGGGCGACGCATCACGGCGCTGGAGCAGAGTCTGGGCTCCAAACTCTTTATCCGCACACCAA
AACTCTATGACCTGAGCCCGCTCGGCGAAACCATGCTGGCTGATGCCAGCGCCATGGAGCAGGCCATCCAGGCCATAGAG
CGCAAGGCAAGCGCCGGGGATCAGAGCCTGTGCGGCGAGGTACGCATCGCCACCACCGATACCCTGGCACAGGCCTTCGT
GCTGCCAGCCCTCACCCTGCTGCGCGAGCGCCATCCCGGCATTCGTCTCAGCCTGCAGACGGCGGTCAACGTCAGTGATA
TCGCCTGTCTCGAAGCCGATCTCGCCATTCGGGGCATGCGTCCCGACAACGACGAGCTGGTGATCAAACGCCTCACCACC
ATAGAGATGGGGCTCTACGCCTCTCACGACTATCTGGCCAGACACGGTACACCCAAGTGCGGCCTCGGCCTGAGCCAGCA
TGCCCTGCTGCTGTTTGCCAAAGAGCTGGTCTCCCGCCACTGGCACAGCCTGTGCGGGGAGCCGCTGCACGAGCCGAATG
TGGTGCTGCAGTGCAATGCCCAGCTGCTGTTGTTGGCGGCGGCCCGTCAGGGGCTGGGGATAGCGCTGCTCTCCACCTTT
CTGGCAGACAAAGAGACTGAGCTGGTACGGGTGCTGCCCGCCCTCAGCGATCCGGTCGATATCTGGCTGGTGCTCCACCC
CAACCTGCAGAAGGCCAGCCGGGTGCGCGCCGTGGTGGATGCGCTGGAAGAGGTGTTTCACTGCCGTTAA

Upstream 100 bases:

>100_bases
TCTATTTGCACGCACACCAGGGCACACTTGGCTTGTGATCCCGCCTGTGCTGGCTTCTAATGGGCTCGCCCCAGCGGGGG
GAACTTGAGTGGGAGGCTCG

Downstream 100 bases:

>100_bases
CCAGCACAGAGTGTTCCAGCACAGGGAGTTGCTCGCCATGGCGCAGCTCCCGAGCCCGAGCAGGGGAATATGGTGAGGGA
TAAAGGCCAGTCCCCTCCCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MINWDDARFFLALARQGTLRGAAGVLGVDQATVGRRITALEQSLGSKLFIRTPKLYDLSPLGETMLADASAMEQAIQAIE
RKASAGDQSLCGEVRIATTDTLAQAFVLPALTLLRERHPGIRLSLQTAVNVSDIACLEADLAIRGMRPDNDELVIKRLTT
IEMGLYASHDYLARHGTPKCGLGLSQHALLLFAKELVSRHWHSLCGEPLHEPNVVLQCNAQLLLLAAARQGLGIALLSTF
LADKETELVRVLPALSDPVDIWLVLHPNLQKASRVRAVVDALEEVFHCR

Sequences:

>Translated_289_residues
MINWDDARFFLALARQGTLRGAAGVLGVDQATVGRRITALEQSLGSKLFIRTPKLYDLSPLGETMLADASAMEQAIQAIE
RKASAGDQSLCGEVRIATTDTLAQAFVLPALTLLRERHPGIRLSLQTAVNVSDIACLEADLAIRGMRPDNDELVIKRLTT
IEMGLYASHDYLARHGTPKCGLGLSQHALLLFAKELVSRHWHSLCGEPLHEPNVVLQCNAQLLLLAAARQGLGIALLSTF
LADKETELVRVLPALSDPVDIWLVLHPNLQKASRVRAVVDALEEVFHCR
>Mature_289_residues
MINWDDARFFLALARQGTLRGAAGVLGVDQATVGRRITALEQSLGSKLFIRTPKLYDLSPLGETMLADASAMEQAIQAIE
RKASAGDQSLCGEVRIATTDTLAQAFVLPALTLLRERHPGIRLSLQTAVNVSDIACLEADLAIRGMRPDNDELVIKRLTT
IEMGLYASHDYLARHGTPKCGLGLSQHALLLFAKELVSRHWHSLCGEPLHEPNVVLQCNAQLLLLAAARQGLGIALLSTF
LADKETELVRVLPALSDPVDIWLVLHPNLQKASRVRAVVDALEEVFHCR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=281, Percent_Identity=28.1138790035587, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI145693193, Length=275, Percent_Identity=26.9090909090909, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87081978, Length=288, Percent_Identity=28.125, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787589, Length=275, Percent_Identity=25.0909090909091, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789440, Length=286, Percent_Identity=25.5244755244755, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI157672245, Length=221, Percent_Identity=31.6742081447964, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1789639, Length=286, Percent_Identity=24.1258741258741, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787601, Length=179, Percent_Identity=24.5810055865922, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787128, Length=210, Percent_Identity=23.3333333333333, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31545; Mature: 31545

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINWDDARFFLALARQGTLRGAAGVLGVDQATVGRRITALEQSLGSKLFIRTPKLYDLSP
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCC
LGETMLADASAMEQAIQAIERKASAGDQSLCGEVRIATTDTLAQAFVLPALTLLRERHPG
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCEEEEEHHHHHHHHHHHHHHHHHHCCCC
IRLSLQTAVNVSDIACLEADLAIRGMRPDNDELVIKRLTTIEMGLYASHDYLARHGTPKC
EEEEEEECCCHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCC
GLGLSQHALLLFAKELVSRHWHSLCGEPLHEPNVVLQCNAQLLLLAAARQGLGIALLSTF
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEEHHHCCCHHHHHHHH
LADKETELVRVLPALSDPVDIWLVLHPNLQKASRVRAVVDALEEVFHCR
HCCCHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MINWDDARFFLALARQGTLRGAAGVLGVDQATVGRRITALEQSLGSKLFIRTPKLYDLSP
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCCC
LGETMLADASAMEQAIQAIERKASAGDQSLCGEVRIATTDTLAQAFVLPALTLLRERHPG
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCEEEEEHHHHHHHHHHHHHHHHHHCCCC
IRLSLQTAVNVSDIACLEADLAIRGMRPDNDELVIKRLTTIEMGLYASHDYLARHGTPKC
EEEEEEECCCHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCC
GLGLSQHALLLFAKELVSRHWHSLCGEPLHEPNVVLQCNAQLLLLAAARQGLGIALLSTF
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEEHHHCCCHHHHHHHH
LADKETELVRVLPALSDPVDIWLVLHPNLQKASRVRAVVDALEEVFHCR
HCCCHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]