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The map label for this gene is cpxR [H]

Identifier: 145300465

GI number: 145300465

Start: 3885392

End: 3886072

Strand: Direct

Name: cpxR [H]

Synonym: ASA_3592

Alternate gene names: 145300465

Gene position: 3885392-3886072 (Clockwise)

Preceding gene: 145300459

Following gene: 145300466

Centisome position: 82.63

GC content: 61.82

Gene sequence:

>681_bases
ATGAAGATCCTGTTGGTGGACGATGACCTGGAGCTTGGCACCATGCTGAGTGAATACCTGGGCGGCGAAGGCTTTGTCAC
CACCCATGTGCTGACCGGCAAGAGCGGTGTGCAACACGCTCTTTCCGGCAACTATGTGGCCGTGGTGCTCGATATCATGC
TGCCCGATATCAACGGCAGCGAGGTACTGCGCCAGATCCGCCACGACAGCAAGATCCCCGTCATCATGCTCACCGCCAAG
GGGGACAACATCGACAGGGTGATCGGACTGGAGATGGGGGCCGACGACTATGTGCCCAAGCCTTGTTACCCCAGAGAGCT
GGTCGCCAGGCTGAGGGCCGTGCTGCGACGAGTCGAACCTGCACCGGCGCCAGCTGGCAAGAGTGACGGTTTGCGTCTGG
CGGAACTGACCCTCTCCCCAGCCACTCGCCAGTGTCACTGGCAAGGCGAGCCACTGGAGCTGACCGCCACGGAATTCAAT
CTGCTGGAACTGCTGCTGCGGGCGCCGGAGCGGGTAGTCAGCAAGGATGAGCTATCCCTGCACGGACTGGGCCGCCCGCG
CGAGCCCTATGATCGCAGCGTCGACGTGCACATCTGCAATATCCACCAGAAGCTGCAGGCGCTGGCGGGTGAGGTCATCG
GCATAGAGACGGTGCGCAGCATAGGATACCGGCTGACATGA

Upstream 100 bases:

>100_bases
GGTTAAGCCTCCTGCAGGGCAGTGTAAGGATTGCGTAAAAGCAGCTGCCAGCCGCATGCAGACACGGGAAAATGGCGCCG
ACTCGAGAGGGAGAAGAGCA

Downstream 100 bases:

>100_bases
TCCTCAAGGGCCACCTGTTCTGGAAGATACTGTTCGGCTTCTGGTTCACCATCATAATGATGAGCCAGCTGCTATGGGTC
GCTTTCAGTCTCTACAGCCA

Product: OmpR family two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MKILLVDDDLELGTMLSEYLGGEGFVTTHVLTGKSGVQHALSGNYVAVVLDIMLPDINGSEVLRQIRHDSKIPVIMLTAK
GDNIDRVIGLEMGADDYVPKPCYPRELVARLRAVLRRVEPAPAPAGKSDGLRLAELTLSPATRQCHWQGEPLELTATEFN
LLELLLRAPERVVSKDELSLHGLGRPREPYDRSVDVHICNIHQKLQALAGEVIGIETVRSIGYRLT

Sequences:

>Translated_226_residues
MKILLVDDDLELGTMLSEYLGGEGFVTTHVLTGKSGVQHALSGNYVAVVLDIMLPDINGSEVLRQIRHDSKIPVIMLTAK
GDNIDRVIGLEMGADDYVPKPCYPRELVARLRAVLRRVEPAPAPAGKSDGLRLAELTLSPATRQCHWQGEPLELTATEFN
LLELLLRAPERVVSKDELSLHGLGRPREPYDRSVDVHICNIHQKLQALAGEVIGIETVRSIGYRLT
>Mature_226_residues
MKILLVDDDLELGTMLSEYLGGEGFVTTHVLTGKSGVQHALSGNYVAVVLDIMLPDINGSEVLRQIRHDSKIPVIMLTAK
GDNIDRVIGLEMGADDYVPKPCYPRELVARLRAVLRRVEPAPAPAGKSDGLRLAELTLSPATRQCHWQGEPLELTATEFN
LLELLLRAPERVVSKDELSLHGLGRPREPYDRSVDVHICNIHQKLQALAGEVIGIETVRSIGYRLT

Specific function: Member of a two-component regulatory system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=43.1718061674009, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=38.2222222222222, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=37.219730941704, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=37.9464285714286, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1786599, Length=228, Percent_Identity=36.8421052631579, Blast_Score=137, Evalue=4e-34,
Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=34.4827586206897, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=36.283185840708, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1787229, Length=209, Percent_Identity=34.4497607655502, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790552, Length=226, Percent_Identity=37.1681415929204, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=32.8888888888889, Blast_Score=103, Evalue=7e-24,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=30.8035714285714, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=29.4871794871795, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI145693140, Length=228, Percent_Identity=32.4561403508772, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787375, Length=181, Percent_Identity=33.1491712707182, Blast_Score=85, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24900; Mature: 24900

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILLVDDDLELGTMLSEYLGGEGFVTTHVLTGKSGVQHALSGNYVAVVLDIMLPDINGS
CEEEEECCCCHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHCCCEEEEEEEECCCCCCHH
EVLRQIRHDSKIPVIMLTAKGDNIDRVIGLEMGADDYVPKPCYPRELVARLRAVLRRVEP
HHHHHHHCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCC
APAPAGKSDGLRLAELTLSPATRQCHWQGEPLELTATEFNLLELLLRAPERVVSKDELSL
CCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHCHHHHHCCCCCEE
HGLGRPREPYDRSVDVHICNIHQKLQALAGEVIGIETVRSIGYRLT
ECCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKILLVDDDLELGTMLSEYLGGEGFVTTHVLTGKSGVQHALSGNYVAVVLDIMLPDINGS
CEEEEECCCCHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHCCCEEEEEEEECCCCCCHH
EVLRQIRHDSKIPVIMLTAKGDNIDRVIGLEMGADDYVPKPCYPRELVARLRAVLRRVEP
HHHHHHHCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCC
APAPAGKSDGLRLAELTLSPATRQCHWQGEPLELTATEFNLLELLLRAPERVVSKDELSL
CCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHCHHHHHCCCCCEE
HGLGRPREPYDRSVDVHICNIHQKLQALAGEVIGIETVRSIGYRLT
ECCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]