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The map label for this gene is apaH [H]

Identifier: 145300237

GI number: 145300237

Start: 3625804

End: 3626625

Strand: Direct

Name: apaH [H]

Synonym: ASA_3352

Alternate gene names: 145300237

Gene position: 3625804-3626625 (Clockwise)

Preceding gene: 145300236

Following gene: 145300241

Centisome position: 77.11

GC content: 62.04

Gene sequence:

>822_bases
ATGGCGAACTGTTTTGTTGGCGATATCCAGGGCTGTTATGACGACTTGCGTCGTCTGCTGGATCTCGCAAAGTTCGATCC
AGCCAAGGACGTGCTCTGGCTCTGCGGCGACCTGGTCGCCCGCGGACCGGACTCCCTGAAGACACTGCGCTACGTCAAGT
CGCTGGGCCAGCGGGCCGTCACAGTGCTCGGCAACCACGACCTTCACCTGCTGGCGGTCGCCGATGGCGTTGCGCCGCTC
AAGAAGAAAGACAAGCTGCAAGCCCTGATGGAAGCGCCGGATCGGGACGAGCTGCTGACGTGGTTGCGCCATCGCCCCCT
GCTGGCGGAGCACCCGGATCTGCCCATCATGATGGTGCATGCCGGTATCTCCCCCGCCTGGGACGCCCGAACGGCACGCA
ACTGTGCCCGCGAAGTGGAGAGTCTGCTGCGCGGCGATCAGTACAGCTGGTTGTTGCACAACATGTATGGCGATCTGCCC
GATGGCTGGAGTGAAGATCTGGCAGGTATCGAGCGTTACCGCTACATCATCAACACCTTCACCCGGATGCGCTTCTGCTA
TTTCGATGGCCGACTCGAGTTCAAGTGCAAGAAGGGCCCCACGGAGTCTACTCCCGGCCTGCGCCCCTGGTTCGAGCAGC
GCGAGCACCATATGGATGACCCCATACTGGTATTCGGCCACTGGGCGGCCCTGATGGGCAACACAGGCAGGAACGACATC
AAGGCGCTCGACACCGGCTGCGTGTGGGGCAACAGCCTCACCCTGTGGCGTTATGAAGACGATGCCCTGATAGCGACGCC
CTGCCCCACTCACGCCAAGTGA

Upstream 100 bases:

>100_bases
GGAAGGGAGCTATACCCTGCAAGATGAGTCAGGGCAGCCGTTCGAGGCGCCCATAGCGCCTTTTACCCTGGCCGTCCCAA
ACATTATTAACTGAGGTTTC

Downstream 100 bases:

>100_bases
TGGTTAAGGGCTGCGCCTGAGCGACGAGAGCCTCACTCTGTCGCGTTACACAAGAACAAAGCCCGGCAAGTTGCCGGGCT
TTGTTCTATTCGCACCAATG

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MANCFVGDIQGCYDDLRRLLDLAKFDPAKDVLWLCGDLVARGPDSLKTLRYVKSLGQRAVTVLGNHDLHLLAVADGVAPL
KKKDKLQALMEAPDRDELLTWLRHRPLLAEHPDLPIMMVHAGISPAWDARTARNCAREVESLLRGDQYSWLLHNMYGDLP
DGWSEDLAGIERYRYIINTFTRMRFCYFDGRLEFKCKKGPTESTPGLRPWFEQREHHMDDPILVFGHWAALMGNTGRNDI
KALDTGCVWGNSLTLWRYEDDALIATPCPTHAK

Sequences:

>Translated_273_residues
MANCFVGDIQGCYDDLRRLLDLAKFDPAKDVLWLCGDLVARGPDSLKTLRYVKSLGQRAVTVLGNHDLHLLAVADGVAPL
KKKDKLQALMEAPDRDELLTWLRHRPLLAEHPDLPIMMVHAGISPAWDARTARNCAREVESLLRGDQYSWLLHNMYGDLP
DGWSEDLAGIERYRYIINTFTRMRFCYFDGRLEFKCKKGPTESTPGLRPWFEQREHHMDDPILVFGHWAALMGNTGRNDI
KALDTGCVWGNSLTLWRYEDDALIATPCPTHAK
>Mature_272_residues
ANCFVGDIQGCYDDLRRLLDLAKFDPAKDVLWLCGDLVARGPDSLKTLRYVKSLGQRAVTVLGNHDLHLLAVADGVAPLK
KKDKLQALMEAPDRDELLTWLRHRPLLAEHPDLPIMMVHAGISPAWDARTARNCAREVESLLRGDQYSWLLHNMYGDLPD
GWSEDLAGIERYRYIINTFTRMRFCYFDGRLEFKCKKGPTESTPGLRPWFEQREHHMDDPILVFGHWAALMGNTGRNDIK
ALDTGCVWGNSLTLWRYEDDALIATPCPTHAK

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=271, Percent_Identity=51.2915129151292, Blast_Score=283, Evalue=6e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843
- InterPro:   IPR006186 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 31103; Mature: 30972

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANCFVGDIQGCYDDLRRLLDLAKFDPAKDVLWLCGDLVARGPDSLKTLRYVKSLGQRAV
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHE
TVLGNHDLHLLAVADGVAPLKKKDKLQALMEAPDRDELLTWLRHRPLLAEHPDLPIMMVH
EEECCCCEEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCEEEEE
AGISPAWDARTARNCAREVESLLRGDQYSWLLHNMYGDLPDGWSEDLAGIERYRYIINTF
CCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
TRMRFCYFDGRLEFKCKKGPTESTPGLRPWFEQREHHMDDPILVFGHWAALMGNTGRNDI
HHHHEEEECCEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCEEEEEHHHHHHCCCCCCHH
KALDTGCVWGNSLTLWRYEDDALIATPCPTHAK
HHHHCCEEECCCEEEEEECCCCEEECCCCCCCC
>Mature Secondary Structure 
ANCFVGDIQGCYDDLRRLLDLAKFDPAKDVLWLCGDLVARGPDSLKTLRYVKSLGQRAV
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHE
TVLGNHDLHLLAVADGVAPLKKKDKLQALMEAPDRDELLTWLRHRPLLAEHPDLPIMMVH
EEECCCCEEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCEEEEE
AGISPAWDARTARNCAREVESLLRGDQYSWLLHNMYGDLPDGWSEDLAGIERYRYIINTF
CCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
TRMRFCYFDGRLEFKCKKGPTESTPGLRPWFEQREHHMDDPILVFGHWAALMGNTGRNDI
HHHHEEEECCEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCEEEEEHHHHHHCCCCCCHH
KALDTGCVWGNSLTLWRYEDDALIATPCPTHAK
HHHHCCEEECCCEEEEEECCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA