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The map label for this gene is cheB [H]

Identifier: 145300167

GI number: 145300167

Start: 3538405

End: 3539466

Strand: Direct

Name: cheB [H]

Synonym: ASA_3272

Alternate gene names: 145300167

Gene position: 3538405-3539466 (Clockwise)

Preceding gene: 145300166

Following gene: 145300173

Centisome position: 75.25

GC content: 61.49

Gene sequence:

>1062_bases
ATGAAACAGATCAAGGTCATGCTGGTGGACGACTCCGCCGTGGTCAGGCAGGTATTACAGGCCATTCTCGAACAGGAGCC
GGACATCAAGGTGATAGCCACCGCCTCGGATCCGCTGTTTGCACTGGAAAAACTGAAAAAAGAGTGGCCCGACGTGATAG
TGCTGGACGTGGAGATGCCACGCATGGATGGCATCACCTTCCTCACCAAGATCATGGCCGAACACCCTACCCCGGTAGTC
ATCTGCTCGTCCCTGACAGAGAAAGGCGCGGAAACAACGCTGCAGGCCATGGCCGCCGGAGCGGTGGACATCATCACCAA
GCCCACGGTCGGCCTCAAAAGCTTCTTGCAGGAGTCGGCACAAGCCTTGGCCATGGCGGTGCGCGCAGCCGCCCAGGCCA
ATGTCAAACGGCTGGGCAAGGCGCCCCCGTTGATCGTGGCGGCCAAACTCAGCGCCGATGCCATCATGCCGCCAGCAAGC
CAGCATGCCATGGCCCAGACCACGGAGCGGATCGTGGCGATCGGTACCTCCACCGGCGGTACCCAGGCACTGGAAGCCGT
GCTGACGAACCTGCCACGGGTCTGTCCCGGCATCGTCATAGTGCAGCACATGCCGGAGAAGTTCACTGCCTCCTTTGCCG
AGCGGCTCAACAACCTGTGCCAGATCGAGGTGAGAGAGGCCAAAAGCAACGACAGGGTCATTCCGGGTCTGGCACTCATA
GCCCCCGGCGGCAAGCACATGCTGCTCAAGCGCAGCGGCGCCTATTATCACGTCGATGTCATGGATGGCCCCCTCATCAA
CCGCCATCGCCCCTCGGTGGATGTGCTGTTTCGCTCGGTCGCCAAGTTTGCCGGCGGCAATGCCACCGGCATCATAATGA
CGGGCATGGGAGATGACGGCGCTCGCGGGTTACGGGAAATGCTGGAGGCGGGGGCCAACACCTTCGCCCAGGATGAGGCG
TCCTGCGTGGTGTTCGGCATGCCCAAGGAGGCTATCAAGCTCGGGGCTGCCCGCCACATACTGCCGCTGCAGGATATTCA
CCACGCCATAGTGGGTCGATAA

Upstream 100 bases:

>100_bases
CATCTCGGACATGCAGGACACAGAAGCCTGATCTTTGAACTGGCCAGCGGCAATGTCTGGGTTCGTCATCATCGGCTGCC
ACATCGTTAAGGGAACGGGA

Downstream 100 bases:

>100_bases
AACGCGCGTTCAGCCACTGGCGAAATGTGCCCGGCCTGCCGGGCACAGCTGTTTCAGGCGGGCATGTCGTCGAGCAGGGC
GAACAGCCGGTCGATCTCGG

Product: chemotaxis-specific methylesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MKQIKVMLVDDSAVVRQVLQAILEQEPDIKVIATASDPLFALEKLKKEWPDVIVLDVEMPRMDGITFLTKIMAEHPTPVV
ICSSLTEKGAETTLQAMAAGAVDIITKPTVGLKSFLQESAQALAMAVRAAAQANVKRLGKAPPLIVAAKLSADAIMPPAS
QHAMAQTTERIVAIGTSTGGTQALEAVLTNLPRVCPGIVIVQHMPEKFTASFAERLNNLCQIEVREAKSNDRVIPGLALI
APGGKHMLLKRSGAYYHVDVMDGPLINRHRPSVDVLFRSVAKFAGGNATGIIMTGMGDDGARGLREMLEAGANTFAQDEA
SCVVFGMPKEAIKLGAARHILPLQDIHHAIVGR

Sequences:

>Translated_353_residues
MKQIKVMLVDDSAVVRQVLQAILEQEPDIKVIATASDPLFALEKLKKEWPDVIVLDVEMPRMDGITFLTKIMAEHPTPVV
ICSSLTEKGAETTLQAMAAGAVDIITKPTVGLKSFLQESAQALAMAVRAAAQANVKRLGKAPPLIVAAKLSADAIMPPAS
QHAMAQTTERIVAIGTSTGGTQALEAVLTNLPRVCPGIVIVQHMPEKFTASFAERLNNLCQIEVREAKSNDRVIPGLALI
APGGKHMLLKRSGAYYHVDVMDGPLINRHRPSVDVLFRSVAKFAGGNATGIIMTGMGDDGARGLREMLEAGANTFAQDEA
SCVVFGMPKEAIKLGAARHILPLQDIHHAIVGR
>Mature_353_residues
MKQIKVMLVDDSAVVRQVLQAILEQEPDIKVIATASDPLFALEKLKKEWPDVIVLDVEMPRMDGITFLTKIMAEHPTPVV
ICSSLTEKGAETTLQAMAAGAVDIITKPTVGLKSFLQESAQALAMAVRAAAQANVKRLGKAPPLIVAAKLSADAIMPPAS
QHAMAQTTERIVAIGTSTGGTQALEAVLTNLPRVCPGIVIVQHMPEKFTASFAERLNNLCQIEVREAKSNDRVIPGLALI
APGGKHMLLKRSGAYYHVDVMDGPLINRHRPSVDVLFRSVAKFAGGNATGIIMTGMGDDGARGLREMLEAGANTFAQDEA
SCVVFGMPKEAIKLGAARHILPLQDIHHAIVGR

Specific function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR [H]

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788192, Length=353, Percent_Identity=49.8583569405099, Blast_Score=348, Evalue=2e-97,
Organism=Escherichia coli, GI87082052, Length=105, Percent_Identity=29.5238095238095, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR008248
- InterPro:   IPR000673
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01339 CheB_methylest; PF00072 Response_reg [H]

EC number: =3.1.1.61 [H]

Molecular weight: Translated: 37709; Mature: 37709

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50122 CHEB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQIKVMLVDDSAVVRQVLQAILEQEPDIKVIATASDPLFALEKLKKEWPDVIVLDVEMP
CCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEEECCC
RMDGITFLTKIMAEHPTPVVICSSLTEKGAETTLQAMAAGAVDIITKPTVGLKSFLQESA
CCCCHHHHHHHHHCCCCCEEEECHHHHCCHHHHHHHHHCCCHHEECCCCHHHHHHHHHHH
QALAMAVRAAAQANVKRLGKAPPLIVAAKLSADAIMPPASQHAMAQTTERIVAIGTSTGG
HHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCEEEEEECCCCH
TQALEAVLTNLPRVCPGIVIVQHMPEKFTASFAERLNNLCQIEVREAKSNDRVIPGLALI
HHHHHHHHHHCHHHCCCCEEEHHCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEEE
APGGKHMLLKRSGAYYHVDVMDGPLINRHRPSVDVLFRSVAKFAGGNATGIIMTGMGDDG
CCCCCEEEEEECCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCH
ARGLREMLEAGANTFAQDEASCVVFGMPKEAIKLGAARHILPLQDIHHAIVGR
HHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHCCHHCCCCHHHHHHHHCCC
>Mature Secondary Structure
MKQIKVMLVDDSAVVRQVLQAILEQEPDIKVIATASDPLFALEKLKKEWPDVIVLDVEMP
CCCEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCEEEEEECCC
RMDGITFLTKIMAEHPTPVVICSSLTEKGAETTLQAMAAGAVDIITKPTVGLKSFLQESA
CCCCHHHHHHHHHCCCCCEEEECHHHHCCHHHHHHHHHCCCHHEECCCCHHHHHHHHHHH
QALAMAVRAAAQANVKRLGKAPPLIVAAKLSADAIMPPASQHAMAQTTERIVAIGTSTGG
HHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCEEEEEECCCCH
TQALEAVLTNLPRVCPGIVIVQHMPEKFTASFAERLNNLCQIEVREAKSNDRVIPGLALI
HHHHHHHHHHCHHHCCCCEEEHHCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEEE
APGGKHMLLKRSGAYYHVDVMDGPLINRHRPSVDVLFRSVAKFAGGNATGIIMTGMGDDG
CCCCCEEEEEECCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCH
ARGLREMLEAGANTFAQDEASCVVFGMPKEAIKLGAARHILPLQDIHHAIVGR
HHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHCCHHCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA