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The map label for this gene is yciA [H]

Identifier: 145299650

GI number: 145299650

Start: 2922362

End: 2922832

Strand: Direct

Name: yciA [H]

Synonym: ASA_2724

Alternate gene names: 145299650

Gene position: 2922362-2922832 (Clockwise)

Preceding gene: 145299648

Following gene: 145299651

Centisome position: 62.15

GC content: 62.63

Gene sequence:

>471_bases
ATGACCCCACCCCGCGAGCTGACCCTGCAGTTTCTGGCAGAACCCGCCGACGTGAACTTTGGCGGCAAGGTGCACGGCGG
CATGGTGATGAAGTGGATCGATCAGGCCGGTTACGCCTGCGCCGCCGGCTGGTGCAGCGGCTATGCGGTCACCGTCTACG
TGGGGGGGATCCGCTTCCTGCGGCCCATCCAGATAGGCCAGCTTGTGGAAGTACACGCCGAGGTGATCCACACAGGCACC
ACCAGCATGCACCTGGCGGTGGATATCTACAGCCGCCATCCAGCGGACCGGCAGCGCCACAAAACTACCCACTGCATCAT
CATCTTCGTCGCCATGGACGAGACGGGCACACCGACCAGGGTGCCCCAGTGGCAACCTGTCTCGGCCGCCGATCTGAGCT
TGCAGCAATACGCCAAAAAACTGATGGCCCTGCGCGAGGAGATAGACAAGGAGATGCGTCAGCACCTCTGA

Upstream 100 bases:

>100_bases
TTCGCGGTATACCTGACATAAATGCTGGCCAGCTTCTCAGGCCCGCCATGGCGCCAATGAACCAACCGGTACCGCGACTA
TGTCAAGACAAGGAGAGAGC

Downstream 100 bases:

>100_bases
GCCCTTCATCGCCCGTGATACAGGGCCGGTCCCTATCCGGGTGCGGCTGTGTATAATGGCGCTTTTCCCATTACGGAGTC
TGTCATGTCACTGGAAAATG

Product: acyl-CoA thioester hydrolase-related protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MTPPRELTLQFLAEPADVNFGGKVHGGMVMKWIDQAGYACAAGWCSGYAVTVYVGGIRFLRPIQIGQLVEVHAEVIHTGT
TSMHLAVDIYSRHPADRQRHKTTHCIIIFVAMDETGTPTRVPQWQPVSAADLSLQQYAKKLMALREEIDKEMRQHL

Sequences:

>Translated_156_residues
MTPPRELTLQFLAEPADVNFGGKVHGGMVMKWIDQAGYACAAGWCSGYAVTVYVGGIRFLRPIQIGQLVEVHAEVIHTGT
TSMHLAVDIYSRHPADRQRHKTTHCIIIFVAMDETGTPTRVPQWQPVSAADLSLQQYAKKLMALREEIDKEMRQHL
>Mature_155_residues
TPPRELTLQFLAEPADVNFGGKVHGGMVMKWIDQAGYACAAGWCSGYAVTVYVGGIRFLRPIQIGQLVEVHAEVIHTGTT
SMHLAVDIYSRHPADRQRHKTTHCIIIFVAMDETGTPTRVPQWQPVSAADLSLQQYAKKLMALREEIDKEMRQHL

Specific function: Catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA [H]

COG id: COG1607

COG function: function code I; Acyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl coenzyme A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1787506, Length=123, Percent_Identity=35.7723577235772, Blast_Score=82, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006683 [H]

Pfam domain/function: PF03061 4HBT [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 17455; Mature: 17324

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPPRELTLQFLAEPADVNFGGKVHGGMVMKWIDQAGYACAAGWCSGYAVTVYVGGIRFL
CCCHHHHHHHHHCCCCCCCCCCEECCCHHHHHHHHCCCEEEHHCCCCEEEEEEECCCHHC
RPIQIGQLVEVHAEVIHTGTTSMHLAVDIYSRHPADRQRHKTTHCIIIFVAMDETGTPTR
CHHCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHCCCEEEEEEEEEECCCCCCCC
VPQWQPVSAADLSLQQYAKKLMALREEIDKEMRQHL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TPPRELTLQFLAEPADVNFGGKVHGGMVMKWIDQAGYACAAGWCSGYAVTVYVGGIRFL
CCHHHHHHHHHCCCCCCCCCCEECCCHHHHHHHHCCCEEEHHCCCCEEEEEEECCCHHC
RPIQIGQLVEVHAEVIHTGTTSMHLAVDIYSRHPADRQRHKTTHCIIIFVAMDETGTPTR
CHHCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHCCCEEEEEEEEEECCCCCCCC
VPQWQPVSAADLSLQQYAKKLMALREEIDKEMRQHL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]