| Definition | Aeromonas salmonicida subsp. salmonicida A449, complete genome. |
|---|---|
| Accession | NC_009348 |
| Length | 4,702,402 |
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The map label for this gene is phaB [H]
Identifier: 145299299
GI number: 145299299
Start: 2489010
End: 2489750
Strand: Direct
Name: phaB [H]
Synonym: ASA_2343
Alternate gene names: 145299299
Gene position: 2489010-2489750 (Clockwise)
Preceding gene: 145299295
Following gene: 145299301
Centisome position: 52.93
GC content: 64.1
Gene sequence:
>741_bases ATGAAAAAAATTGCCTTGATCACCGGAGCCCGTGGCGGCATCGGATCCGCCATCACCACTGCCTTGCTGGCTCAGGGGTA TCGCATCATCGCCACCCACTCCAGCGGCAACAGTGTGGCGGCCCACGACTGGTACGGGGAGCAGGGCTATCGGCCGGATC AGGTGCGGCTGCTGCCGCTGGACGTGGCCGACACCGCCATGTGTCGTGAAACCCTGGGCCGCCTGTTGCAAGACGAGGGC CGAGTGGACGTGCTGGTCAACAACGCCGGCATCACCCGGGATGGCGCCTTCAAGCGCATGGCGCCGGAGCAGTGGTTCGA GGTGATCCACACCAATCTGTGCAGCCTCTACAACGTGACCCAGCCGCTGTTCGACGCCATGTGCGAGCAGCGCGATGCCC GCATCATCAACATCTCCTCGGTCAACGGCCAGAAGGGACAGTTTGGTCAGGTCAACTACTCGGCGGCCAAGGCGGGCATG CTGGGCTTTACCAAGGCGCTGGCGGCAGAGGGGGCCCGCTTCGGGGTCACGGTCAACGCCATCGCCCCCGGTTACACAGC CACCCCCATGGTGGAGGCGATCCGCAGCGATATCCTCGACAGCATCAAGGCCGACATTCCCATGCGCCGCCTCGCCAAGC CGGAGGAGATCGCCGCCGCAGTGGCCTTTCTCGCGAGCGAAGCGGGCGCCTATATCACGGGGGAAACCCTGGCCATCAAC GGCGGCCTTTATATGAAATAG
Upstream 100 bases:
>100_bases AGTGACGCGTTTCCCTGTCAGATTGTTTGAAAACAAATATATCAATTAGATTTGAAAGCCCATAAAGTCCTCGTTCGAAT CTTTATCAGGGAGAGCCAAG
Downstream 100 bases:
>100_bases CGCCGGGATCAAGGCGAATGACAGAGGGCAGCCAACAGGCTGCCCTCTGTGTTTGCAAGTCGGGACGAGATAGTTGCCAC CCGGCTCAGGGGCGCGCCGG
Product: acetoacetyl-CoA reductase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 246; Mature: 246
Protein sequence:
>246_residues MKKIALITGARGGIGSAITTALLAQGYRIIATHSSGNSVAAHDWYGEQGYRPDQVRLLPLDVADTAMCRETLGRLLQDEG RVDVLVNNAGITRDGAFKRMAPEQWFEVIHTNLCSLYNVTQPLFDAMCEQRDARIINISSVNGQKGQFGQVNYSAAKAGM LGFTKALAAEGARFGVTVNAIAPGYTATPMVEAIRSDILDSIKADIPMRRLAKPEEIAAAVAFLASEAGAYITGETLAIN GGLYMK
Sequences:
>Translated_246_residues MKKIALITGARGGIGSAITTALLAQGYRIIATHSSGNSVAAHDWYGEQGYRPDQVRLLPLDVADTAMCRETLGRLLQDEG RVDVLVNNAGITRDGAFKRMAPEQWFEVIHTNLCSLYNVTQPLFDAMCEQRDARIINISSVNGQKGQFGQVNYSAAKAGM LGFTKALAAEGARFGVTVNAIAPGYTATPMVEAIRSDILDSIKADIPMRRLAKPEEIAAAVAFLASEAGAYITGETLAIN GGLYMK >Mature_246_residues MKKIALITGARGGIGSAITTALLAQGYRIIATHSSGNSVAAHDWYGEQGYRPDQVRLLPLDVADTAMCRETLGRLLQDEG RVDVLVNNAGITRDGAFKRMAPEQWFEVIHTNLCSLYNVTQPLFDAMCEQRDARIINISSVNGQKGQFGQVNYSAAKAGM LGFTKALAAEGARFGVTVNAIAPGYTATPMVEAIRSDILDSIKADIPMRRLAKPEEIAAAVAFLASEAGAYITGETLAIN GGLYMK
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254992, Length=247, Percent_Identity=35.6275303643725, Blast_Score=142, Evalue=3e-34, Organism=Homo sapiens, GI15277342, Length=251, Percent_Identity=36.6533864541833, Blast_Score=140, Evalue=1e-33, Organism=Homo sapiens, GI4504505, Length=250, Percent_Identity=32, Blast_Score=104, Evalue=7e-23, Organism=Homo sapiens, GI31542939, Length=210, Percent_Identity=34.2857142857143, Blast_Score=102, Evalue=4e-22, Organism=Homo sapiens, GI19923817, Length=247, Percent_Identity=27.9352226720648, Blast_Score=98, Evalue=7e-21, Organism=Homo sapiens, GI66933014, Length=251, Percent_Identity=30.2788844621514, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI32483357, Length=255, Percent_Identity=28.6274509803922, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI59889578, Length=183, Percent_Identity=35.5191256830601, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI10190704, Length=253, Percent_Identity=28.8537549407115, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI4758504, Length=260, Percent_Identity=27.6923076923077, Blast_Score=82, Evalue=3e-16, Organism=Homo sapiens, GI224922801, Length=179, Percent_Identity=32.9608938547486, Blast_Score=81, Evalue=8e-16, Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=27.8225806451613, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI20149619, Length=202, Percent_Identity=28.2178217821782, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI4503301, Length=195, Percent_Identity=27.6923076923077, Blast_Score=76, Evalue=2e-14, Organism=Homo sapiens, GI109715829, Length=231, Percent_Identity=26.4069264069264, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI7706318, Length=192, Percent_Identity=24.4791666666667, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI126723750, Length=258, Percent_Identity=26.7441860465116, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI5031737, Length=244, Percent_Identity=25.4098360655738, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI150247226, Length=199, Percent_Identity=31.1557788944724, Blast_Score=68, Evalue=6e-12, Organism=Homo sapiens, GI83715985, Length=261, Percent_Identity=26.0536398467433, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI4503817, Length=220, Percent_Identity=26.8181818181818, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=47.9508196721311, Blast_Score=213, Evalue=1e-56, Organism=Escherichia coli, GI87082100, Length=249, Percent_Identity=38.1526104417671, Blast_Score=147, Evalue=5e-37, Organism=Escherichia coli, GI1788459, Length=247, Percent_Identity=34.8178137651822, Blast_Score=129, Evalue=3e-31, Organism=Escherichia coli, GI1790717, Length=243, Percent_Identity=30.4526748971193, Blast_Score=114, Evalue=8e-27, Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=29.6, Blast_Score=108, Evalue=4e-25, Organism=Escherichia coli, GI1789208, Length=247, Percent_Identity=30.3643724696356, Blast_Score=107, Evalue=8e-25, Organism=Escherichia coli, GI1786812, Length=252, Percent_Identity=28.968253968254, Blast_Score=102, Evalue=2e-23, Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=29.7959183673469, Blast_Score=87, Evalue=7e-19, Organism=Escherichia coli, GI1789378, Length=251, Percent_Identity=27.8884462151394, Blast_Score=81, Evalue=5e-17, Organism=Escherichia coli, GI2367365, Length=243, Percent_Identity=29.6296296296296, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1789057, Length=270, Percent_Identity=26.2962962962963, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1787820, Length=226, Percent_Identity=29.646017699115, Blast_Score=73, Evalue=1e-14, Organism=Escherichia coli, GI1787905, Length=241, Percent_Identity=26.9709543568465, Blast_Score=73, Evalue=2e-14, Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=39.4308943089431, Blast_Score=164, Evalue=5e-41, Organism=Caenorhabditis elegans, GI17555706, Length=250, Percent_Identity=38.8, Blast_Score=157, Evalue=3e-39, Organism=Caenorhabditis elegans, GI17560676, Length=259, Percent_Identity=28.957528957529, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=31.3253012048193, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=28.7449392712551, Blast_Score=97, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17568967, Length=209, Percent_Identity=27.2727272727273, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI17561402, Length=248, Percent_Identity=29.4354838709677, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17562906, Length=256, Percent_Identity=26.953125, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17562910, Length=256, Percent_Identity=27.734375, Blast_Score=91, Evalue=7e-19, Organism=Caenorhabditis elegans, GI17562908, Length=256, Percent_Identity=27.734375, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI193204405, Length=256, Percent_Identity=28.515625, Blast_Score=87, Evalue=9e-18, Organism=Caenorhabditis elegans, GI17562904, Length=256, Percent_Identity=28.125, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17561272, Length=190, Percent_Identity=31.5789473684211, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17551412, Length=262, Percent_Identity=28.2442748091603, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=27.0992366412214, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI17562990, Length=254, Percent_Identity=27.9527559055118, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17560150, Length=254, Percent_Identity=27.9527559055118, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17536025, Length=249, Percent_Identity=28.5140562248996, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17560332, Length=260, Percent_Identity=27.6923076923077, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17538182, Length=259, Percent_Identity=29.3436293436293, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17531453, Length=256, Percent_Identity=26.953125, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI72000259, Length=254, Percent_Identity=27.9527559055118, Blast_Score=77, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=27.6923076923077, Blast_Score=77, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17538486, Length=257, Percent_Identity=24.9027237354086, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI17536651, Length=249, Percent_Identity=27.710843373494, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI17560220, Length=260, Percent_Identity=27.6923076923077, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17508651, Length=253, Percent_Identity=26.8774703557312, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17563726, Length=254, Percent_Identity=25.1968503937008, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI115534694, Length=258, Percent_Identity=28.2945736434109, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17544670, Length=260, Percent_Identity=23.8461538461538, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI17508895, Length=197, Percent_Identity=26.9035532994924, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17565030, Length=260, Percent_Identity=25.3846153846154, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI193203115, Length=194, Percent_Identity=26.2886597938144, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI193203117, Length=196, Percent_Identity=26.0204081632653, Blast_Score=67, Evalue=7e-12, Organism=Saccharomyces cerevisiae, GI6322861, Length=232, Percent_Identity=30.6034482758621, Blast_Score=110, Evalue=3e-25, Organism=Saccharomyces cerevisiae, GI6324126, Length=248, Percent_Identity=23.7903225806452, Blast_Score=69, Evalue=7e-13, Organism=Drosophila melanogaster, GI24639444, Length=244, Percent_Identity=36.0655737704918, Blast_Score=145, Evalue=2e-35, Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=32.4, Blast_Score=110, Evalue=1e-24, Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=32.4, Blast_Score=109, Evalue=2e-24, Organism=Drosophila melanogaster, GI18859837, Length=241, Percent_Identity=35.6846473029046, Blast_Score=105, Evalue=2e-23, Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=31.6, Blast_Score=104, Evalue=4e-23, Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=30.8, Blast_Score=103, Evalue=1e-22, Organism=Drosophila melanogaster, GI24643142, Length=244, Percent_Identity=29.5081967213115, Blast_Score=95, Evalue=5e-20, Organism=Drosophila melanogaster, GI21355319, Length=244, Percent_Identity=27.4590163934426, Blast_Score=88, Evalue=4e-18, Organism=Drosophila melanogaster, GI24644337, Length=209, Percent_Identity=32.5358851674641, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI17737361, Length=258, Percent_Identity=31.0077519379845, Blast_Score=85, Evalue=4e-17, Organism=Drosophila melanogaster, GI21358495, Length=193, Percent_Identity=29.5336787564767, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI116007236, Length=198, Percent_Identity=27.7777777777778, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI221331218, Length=221, Percent_Identity=28.0542986425339, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI221331216, Length=221, Percent_Identity=28.0542986425339, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI24665247, Length=221, Percent_Identity=28.0542986425339, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI24665243, Length=221, Percent_Identity=28.0542986425339, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI24641232, Length=238, Percent_Identity=28.1512605042017, Blast_Score=67, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011283 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.36 [H]
Molecular weight: Translated: 26326; Mature: 26326
Theoretical pI: Translated: 7.43; Mature: 7.43
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 3.3 %Met (Translated Protein) 4.5 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 3.3 %Met (Mature Protein) 4.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKKIALITGARGGIGSAITTALLAQGYRIIATHSSGNSVAAHDWYGEQGYRPDQVRLLPL CCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCCEEEECCCCCCCCCCCCEEEEEE DVADTAMCRETLGRLLQDEGRVDVLVNNAGITRDGAFKRMAPEQWFEVIHTNLCSLYNVT CHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHH QPLFDAMCEQRDARIINISSVNGQKGQFGQVNYSAAKAGMLGFTKALAAEGARFGVTVNA HHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEE IAPGYTATPMVEAIRSDILDSIKADIPMRRLAKPEEIAAAVAFLASEAGAYITGETLAIN ECCCCCHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHCCCCEEECCEEEEC GGLYMK CCEECC >Mature Secondary Structure MKKIALITGARGGIGSAITTALLAQGYRIIATHSSGNSVAAHDWYGEQGYRPDQVRLLPL CCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCCEEEECCCCCCCCCCCCEEEEEE DVADTAMCRETLGRLLQDEGRVDVLVNNAGITRDGAFKRMAPEQWFEVIHTNLCSLYNVT CHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHH QPLFDAMCEQRDARIINISSVNGQKGQFGQVNYSAAKAGMLGFTKALAAEGARFGVTVNA HHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEE IAPGYTATPMVEAIRSDILDSIKADIPMRRLAKPEEIAAAVAFLASEAGAYITGETLAIN ECCCCCHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHCCCCEEECCEEEEC GGLYMK CCEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7635832 [H]