Click here to switch to the map view.

The map label for this gene is dadA [H]

Identifier: 145299289

GI number: 145299289

Start: 2474528

End: 2475781

Strand: Direct

Name: dadA [H]

Synonym: ASA_2333

Alternate gene names: 145299289

Gene position: 2474528-2475781 (Clockwise)

Preceding gene: 145299288

Following gene: 145299291

Centisome position: 52.62

GC content: 63.24

Gene sequence:

>1254_bases
ATGGACATAGTGGTACTCGGTGGTGGCGTGGTCGGTGTGACCAGCGCCTGGTATCTGGCCAAAGCGGGCCACAAGGTAAC
CCTGCTGGAGCGACGGGACGGGGTGGCGCTGGAGACCAGCCATGCCAACGCCGGCCAGATCTCCCCCGGCTATGCGGCAC
CCTGGGCGGCGCCCGGCATTCCCCTCAAGGCCGCCAAATGGCTGCTGCAAAAACATGCGCCTTTCACGGTGCGCCCGACC
TCGGATCCTTTCCAGCTGCGCTGGATGCTGAAGATGTTCGCCAACTGCACCCCGGCAGCCTATGCCACCAACAAGGGACG
CATGGTACGCCTCGCCGAATACAGCCGCGACTGCATGAAGACGCTGCGAGACGAGCTTGCACTGGACTACGAAGGACGCC
AGCTCGGCACCTTGCAGCTGTTTCGAAGCCAGGCCCAGCTCGATGCCAGCAAACGAGATATCGAGGTGCTGGAAGAGTAT
GGCGTCCCCTATCAGTCACTGGATGCCAGTGGTTGTGAAGGGGTTGAACCGGCATTGGCACGGGTACGTGGCAAGATAGT
GGGCGGCCTGCGCCTGCCGGGAGATGAAACCGGCGACTGTTTCCGCTTCACCAAGGCACTGGCCGCCGAGGCGCAAAAAC
TCGGGGTGGAGTTTGTCTTCAACTGCGCCATCGACGAGATTGAGCTCTCTTTGGGGCGCGCCGTGGCGGTGCGGGCCGGT
GAGCAGCGTTTCAAGGCAGATGCCATCGTCTGCGCGCTGGGCAGCTATGCTACCGGCTTCCTTCGTCCGCTTGGGATCGA
TCTGCCTGTCTATCCGGTCAAAGGTTACTCCCTGACCCTGCCCATGACAGATGCCGATGCGGTGCCCCGCAGTACAGTGC
TGGATGAAACCTACAAGGTGGCCATCACCCGCTTTAACGAGCGGATCCGGGTCGGTGGCATGGCAGAGCTGTCGGGTTTC
AATCTGGCACTCAATCCCAAGCGTTACGACACCCTGGCCATGGTGGTGGGGGATCTTTTCCCCGAAGGGGGCGATATCAG
CCGCGCCGAGTTCTGGACCGGACTGCGACCCATGACACCGGACGGCACTCCCCTGGTGGGGCCAAGCCCGGTCCCCGGAC
TCTGGCTCAACACAGGCCACGGCACCCTGGGCTGGACCATGGCAGCCGGCTCGGGTCAGCTGCTGAGCGATCTGATCAGC
GGCAGCTCGACGGCCATCAGCGACGAGGGGCTGACCCTAGCCCGCTACGGGTAA

Upstream 100 bases:

>100_bases
TAAATAATTGTAACCAGATGTATATTCCGATTATATCTATACCAGTTGAATATCCTGTGGCGGCTGATTATGGTGATGGC
CCCAGTCAAGGAGAGACAAG

Downstream 100 bases:

>100_bases
GCCTGCGCCCGTCACGACCGTCGACTAGACACACAAAAGAGGGAGTGCATGGTCACTCCCTCTTTGCATTTAGCCAATAT
CAGTCAGCGGCCTTGACCAT

Product: D-amino acid dehydrogenase small subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MDIVVLGGGVVGVTSAWYLAKAGHKVTLLERRDGVALETSHANAGQISPGYAAPWAAPGIPLKAAKWLLQKHAPFTVRPT
SDPFQLRWMLKMFANCTPAAYATNKGRMVRLAEYSRDCMKTLRDELALDYEGRQLGTLQLFRSQAQLDASKRDIEVLEEY
GVPYQSLDASGCEGVEPALARVRGKIVGGLRLPGDETGDCFRFTKALAAEAQKLGVEFVFNCAIDEIELSLGRAVAVRAG
EQRFKADAIVCALGSYATGFLRPLGIDLPVYPVKGYSLTLPMTDADAVPRSTVLDETYKVAITRFNERIRVGGMAELSGF
NLALNPKRYDTLAMVVGDLFPEGGDISRAEFWTGLRPMTPDGTPLVGPSPVPGLWLNTGHGTLGWTMAAGSGQLLSDLIS
GSSTAISDEGLTLARYG

Sequences:

>Translated_417_residues
MDIVVLGGGVVGVTSAWYLAKAGHKVTLLERRDGVALETSHANAGQISPGYAAPWAAPGIPLKAAKWLLQKHAPFTVRPT
SDPFQLRWMLKMFANCTPAAYATNKGRMVRLAEYSRDCMKTLRDELALDYEGRQLGTLQLFRSQAQLDASKRDIEVLEEY
GVPYQSLDASGCEGVEPALARVRGKIVGGLRLPGDETGDCFRFTKALAAEAQKLGVEFVFNCAIDEIELSLGRAVAVRAG
EQRFKADAIVCALGSYATGFLRPLGIDLPVYPVKGYSLTLPMTDADAVPRSTVLDETYKVAITRFNERIRVGGMAELSGF
NLALNPKRYDTLAMVVGDLFPEGGDISRAEFWTGLRPMTPDGTPLVGPSPVPGLWLNTGHGTLGWTMAAGSGQLLSDLIS
GSSTAISDEGLTLARYG
>Mature_417_residues
MDIVVLGGGVVGVTSAWYLAKAGHKVTLLERRDGVALETSHANAGQISPGYAAPWAAPGIPLKAAKWLLQKHAPFTVRPT
SDPFQLRWMLKMFANCTPAAYATNKGRMVRLAEYSRDCMKTLRDELALDYEGRQLGTLQLFRSQAQLDASKRDIEVLEEY
GVPYQSLDASGCEGVEPALARVRGKIVGGLRLPGDETGDCFRFTKALAAEAQKLGVEFVFNCAIDEIELSLGRAVAVRAG
EQRFKADAIVCALGSYATGFLRPLGIDLPVYPVKGYSLTLPMTDADAVPRSTVLDETYKVAITRFNERIRVGGMAELSGF
NLALNPKRYDTLAMVVGDLFPEGGDISRAEFWTGLRPMTPDGTPLVGPSPVPGLWLNTGHGTLGWTMAAGSGQLLSDLIS
GSSTAISDEGLTLARYG

Specific function: Oxidative deamination of D-amino acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Inner Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DadA oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787438, Length=416, Percent_Identity=61.0576923076923, Blast_Score=522, Evalue=1e-149,
Organism=Drosophila melanogaster, GI20130091, Length=410, Percent_Identity=24.8780487804878, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI28571104, Length=325, Percent_Identity=24.6153846153846, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023080
- InterPro:   IPR006076 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.4.99.1 [H]

Molecular weight: Translated: 44848; Mature: 44848

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIVVLGGGVVGVTSAWYLAKAGHKVTLLERRDGVALETSHANAGQISPGYAAPWAAPGI
CEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCC
PLKAAKWLLQKHAPFTVRPTSDPFQLRWMLKMFANCTPAAYATNKGRMVRLAEYSRDCMK
CHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHCCCCCCEEECCCCCEEEHHHHHHHHHH
TLRDELALDYEGRQLGTLQLFRSQAQLDASKRDIEVLEEYGVPYQSLDASGCEGVEPALA
HHHHHHEECCCCCEEHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHCCCCCCCCCCHHHH
RVRGKIVGGLRLPGDETGDCFRFTKALAAEAQKLGVEFVFNCAIDEIELSLGRAVAVRAG
HHHHHHEECEECCCCCCCHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHCCCEEEEECC
EQRFKADAIVCALGSYATGFLRPLGIDLPVYPVKGYSLTLPMTDADAVPRSTVLDETYKV
CHHHHHHHEEEEHHHHHHHHHHHCCCCCCEEEECCEEEEEECCCCCCCCCHHHHHHHHHH
AITRFNERIRVGGMAELSGFNLALNPKRYDTLAMVVGDLFPEGGDISRAEFWTGLRPMTP
HEEHHCCEEEECCEEEECCCEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCC
DGTPLVGPSPVPGLWLNTGHGTLGWTMAAGSGQLLSDLISGSSTAISDEGLTLARYG
CCCCCCCCCCCCCEEEECCCCCEEEEEECCCCHHHHHHHCCCCCEECCCCEEEEECC
>Mature Secondary Structure
MDIVVLGGGVVGVTSAWYLAKAGHKVTLLERRDGVALETSHANAGQISPGYAAPWAAPGI
CEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCC
PLKAAKWLLQKHAPFTVRPTSDPFQLRWMLKMFANCTPAAYATNKGRMVRLAEYSRDCMK
CHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHCCCCCCEEECCCCCEEEHHHHHHHHHH
TLRDELALDYEGRQLGTLQLFRSQAQLDASKRDIEVLEEYGVPYQSLDASGCEGVEPALA
HHHHHHEECCCCCEEHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHCCCCCCCCCCHHHH
RVRGKIVGGLRLPGDETGDCFRFTKALAAEAQKLGVEFVFNCAIDEIELSLGRAVAVRAG
HHHHHHEECEECCCCCCCHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHCCCEEEEECC
EQRFKADAIVCALGSYATGFLRPLGIDLPVYPVKGYSLTLPMTDADAVPRSTVLDETYKV
CHHHHHHHEEEEHHHHHHHHHHHCCCCCCEEEECCEEEEEECCCCCCCCCHHHHHHHHHH
AITRFNERIRVGGMAELSGFNLALNPKRYDTLAMVVGDLFPEGGDISRAEFWTGLRPMTP
HEEHHCCEEEECCEEEECCCEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCC
DGTPLVGPSPVPGLWLNTGHGTLGWTMAAGSGQLLSDLISGSSTAISDEGLTLARYG
CCCCCCCCCCCCCEEEECCCCCEEEEEECCCCHHHHHHHCCCCCEECCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA