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The map label for this gene is fecD [C]

Identifier: 145299178

GI number: 145299178

Start: 2342907

End: 2343959

Strand: Direct

Name: fecD [C]

Synonym: ASA_2209

Alternate gene names: 145299178

Gene position: 2342907-2343959 (Clockwise)

Preceding gene: 145299177

Following gene: 145299179

Centisome position: 49.82

GC content: 64.86

Gene sequence:

>1053_bases
ATGAATGATTTGGCTGCCTTGCAGCAGACCCTCACCCGTCAGCGGCAACGAGAGCGCCGTCGCTGGCACTGGCTGGTGCT
GCTCGCCCTGGTGCTGTGCATCACGCTGGTGCTCGACATCGCCACCGGCCCTTCCTTGCTGCCCCTTGGTGAGGTGGTCG
ATGCCCTGCTCTCTCCCGCCCAGGCGGACTCCATGACCCTCACCATCGTCTTTGATATGCGCCTGCCCATCGCCCTGATG
GCCCTGGTGGTCGGCGCCTCGCTCGGGCTTGGCGGCGTCCAGATGCAGACCCTGCTGGACAACCCCCTGGCGAGCCCCTA
CACGTTAGGACTCGCGGCTGCGGCCGGGCTTGGCGCTGCACTGGCGCTCTATACCGGCGGTCTCGGGCTCCCTCCCTTGA
TTGCCATTCCGGCCGGGGCCTTCATTCTGTGCATGTTTGCCGCCAGCCTCTTGTTTGGCCTCGCCATGATGCGCAACATC
AGCAGCCAGACCCTGATCCTGGCGGGTATAGCCCTGCTGTTCCTGTTCCAGTCCCTGCTCTCCCTGCTGCAGTTTCTCTC
CTCCCCCGAGCTCAACCAGCAGATCATGTTCTGGCTGTTTGGCAGCCTGATGCGCACCACCTGGGATGCCCTGATCATCA
CGGCCGCCGTCACCCTGATCTGCACCCTGCTCATCTACCGGGATGCCTGGGCCCTCACCAGCCTGCGCCTCGGGGAGGCC
AGGGCACGGAGCCTGGGGGTCAACGTGGACAGGTTACGCATGAAGACCCTGATCCTCGTCGCCCTGCTCACCGCCACTGC
CACCAGCTTTGTCGGCGTCATCGGCTTCGTCGGCCTGGTGGCCCCCCACATAGCCCGCATGCTGGTGGGGGAAGATCAGC
GCTTCCTGATCCCGCTGTCGGCCCTGTGCGGCGCCTGCATGCTGTCGGCAGCCTCGGTGCTCTCCAAATCCATCGTACCC
GGCACCCTCTTTCCCATCGGCATCGTCACCGCCCTGATTGGCGTGCCCTTCTTCATCTGGCTGATCCTCGGCAGGGGGCG
TAAACGTGCTTGA

Upstream 100 bases:

>100_bases
GGGCCGGACTTTCCCGACCCGAGTCGGGAAGTCCCTCTTCGTCATCCCTCTTTAACCCTTGCGGGCGCTCCTTGAGAGCG
CCCGCTTCAGGATGGTTACC

Downstream 100 bases:

>100_bases
AATATCCCGACTCTCCCTCTCCCTTGGGCAGCAAGCCCTGCTACGGGATCTGAGCCTGACTCTGCACCCGGGGCAGGTCC
ATGTGATCATCGGTCCGAAC

Product: ABC-type Fe(III) dicitrate transporter, permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MNDLAALQQTLTRQRQRERRRWHWLVLLALVLCITLVLDIATGPSLLPLGEVVDALLSPAQADSMTLTIVFDMRLPIALM
ALVVGASLGLGGVQMQTLLDNPLASPYTLGLAAAAGLGAALALYTGGLGLPPLIAIPAGAFILCMFAASLLFGLAMMRNI
SSQTLILAGIALLFLFQSLLSLLQFLSSPELNQQIMFWLFGSLMRTTWDALIITAAVTLICTLLIYRDAWALTSLRLGEA
RARSLGVNVDRLRMKTLILVALLTATATSFVGVIGFVGLVAPHIARMLVGEDQRFLIPLSALCGACMLSAASVLSKSIVP
GTLFPIGIVTALIGVPFFIWLILGRGRKRA

Sequences:

>Translated_350_residues
MNDLAALQQTLTRQRQRERRRWHWLVLLALVLCITLVLDIATGPSLLPLGEVVDALLSPAQADSMTLTIVFDMRLPIALM
ALVVGASLGLGGVQMQTLLDNPLASPYTLGLAAAAGLGAALALYTGGLGLPPLIAIPAGAFILCMFAASLLFGLAMMRNI
SSQTLILAGIALLFLFQSLLSLLQFLSSPELNQQIMFWLFGSLMRTTWDALIITAAVTLICTLLIYRDAWALTSLRLGEA
RARSLGVNVDRLRMKTLILVALLTATATSFVGVIGFVGLVAPHIARMLVGEDQRFLIPLSALCGACMLSAASVLSKSIVP
GTLFPIGIVTALIGVPFFIWLILGRGRKRA
>Mature_350_residues
MNDLAALQQTLTRQRQRERRRWHWLVLLALVLCITLVLDIATGPSLLPLGEVVDALLSPAQADSMTLTIVFDMRLPIALM
ALVVGASLGLGGVQMQTLLDNPLASPYTLGLAAAAGLGAALALYTGGLGLPPLIAIPAGAFILCMFAASLLFGLAMMRNI
SSQTLILAGIALLFLFQSLLSLLQFLSSPELNQQIMFWLFGSLMRTTWDALIITAAVTLICTLLIYRDAWALTSLRLGEA
RARSLGVNVDRLRMKTLILVALLTATATSFVGVIGFVGLVAPHIARMLVGEDQRFLIPLSALCGACMLSAASVLSKSIVP
GTLFPIGIVTALIGVPFFIWLILGRGRKRA

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=326, Percent_Identity=38.0368098159509, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1790741, Length=293, Percent_Identity=35.4948805460751, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1788004, Length=353, Percent_Identity=32.8611898016997, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1786805, Length=315, Percent_Identity=37.1428571428571, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1786347, Length=284, Percent_Identity=33.0985915492958, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1786804, Length=312, Percent_Identity=31.7307692307692, Blast_Score=92, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 37375; Mature: 37375

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDLAALQQTLTRQRQRERRRWHWLVLLALVLCITLVLDIATGPSLLPLGEVVDALLSPA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCC
QADSMTLTIVFDMRLPIALMALVVGASLGLGGVQMQTLLDNPLASPYTLGLAAAAGLGAA
CCCCEEEEEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
LALYTGGLGLPPLIAIPAGAFILCMFAASLLFGLAMMRNISSQTLILAGIALLFLFQSLL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
SLLQFLSSPELNQQIMFWLFGSLMRTTWDALIITAAVTLICTLLIYRDAWALTSLRLGEA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RARSLGVNVDRLRMKTLILVALLTATATSFVGVIGFVGLVAPHIARMLVGEDQRFLIPLS
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHH
ALCGACMLSAASVLSKSIVPGTLFPIGIVTALIGVPFFIWLILGRGRKRA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNDLAALQQTLTRQRQRERRRWHWLVLLALVLCITLVLDIATGPSLLPLGEVVDALLSPA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCC
QADSMTLTIVFDMRLPIALMALVVGASLGLGGVQMQTLLDNPLASPYTLGLAAAAGLGAA
CCCCEEEEEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
LALYTGGLGLPPLIAIPAGAFILCMFAASLLFGLAMMRNISSQTLILAGIALLFLFQSLL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
SLLQFLSSPELNQQIMFWLFGSLMRTTWDALIITAAVTLICTLLIYRDAWALTSLRLGEA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RARSLGVNVDRLRMKTLILVALLTATATSFVGVIGFVGLVAPHIARMLVGEDQRFLIPLS
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHH
ALCGACMLSAASVLSKSIVPGTLFPIGIVTALIGVPFFIWLILGRGRKRA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]