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The map label for this gene is minC [H]

Identifier: 145299139

GI number: 145299139

Start: 2304305

End: 2305021

Strand: Direct

Name: minC [H]

Synonym: ASA_2167

Alternate gene names: 145299139

Gene position: 2304305-2305021 (Clockwise)

Preceding gene: 145299136

Following gene: 145299140

Centisome position: 49.0

GC content: 60.81

Gene sequence:

>717_bases
ATGGTTGAGCGCGATAACGAATTGAAAGGGACTACCTTCACTATTTCTGTGTTGCATATCAGCGATGGCAAGCCTGAGCG
GATCCGTCAGTTACTGGCGGCAAAAGTCGCCCAGGCGCCTCAGTTTTTTAATTGTGCCCCCCTCGTCATCAATGTGGAAC
GACTCGCGGATATCCCCGATTTTGACCAGCTCAAAGGGCTGGTCGAGTCAGAGGACTTCGTGCTGGTCGGGATCACGGGC
GCCAGGGATGAGGCGATGAAGACGGCAGCCAAGGCCGCGGGGCTGGCGGTAATGGCCTCTGGCAAGAGCCGCAAGGTCGA
GCCGCTGCCACTGCCGGAACCTACCCCGTCTCCGGTGGCCGAGGTGAAGGCCGCGCCGGCGCCTCTGGTGCCGAGCAAGG
TGCACGTGGGCCCCGTGCGTTCCGGCCAACAGCTCTACGCCGCCGGCACCTCGCTGGTGATACTGGGCTCGGTGAGCCAG
GGGGCCGAAGTCATCGCCGACGACAGCATACATATTTATGGCGCCCTGCGTGGCAGGGCCATTGCCGGTGCCAAGGGCAA
CACCCAGGCACGGATCTATTGCCAGCAATTGCAGGCCGAGCTGCTATCCATCGCAGGCACGTTCCAACTGAGCGATGCAC
TGCCGGCAGGCCTGATACAACAGCCGGTGCATGTCCGGCTGGATAACGAACAACTCCGAATAGACCATATCAAATAG

Upstream 100 bases:

>100_bases
TGATATAATCCGACGGGTTTATTGCCTCTGATGGTGGCAAACTATAACATCAGGAATTGAATAACAATAACGGATTACCG
TCTCTGTCTCGGGGAAGATC

Downstream 100 bases:

>100_bases
AGTTACAAGGAAGCGAGAATGGCGCGAATCATAGTCGTTACATCGGGTAAAGGTGGCGTTGGCAAGACCACAACCAGCGC
GGCCCTGAGTACAGGTTTGG

Product: septum site-determining protein MinC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MVERDNELKGTTFTISVLHISDGKPERIRQLLAAKVAQAPQFFNCAPLVINVERLADIPDFDQLKGLVESEDFVLVGITG
ARDEAMKTAAKAAGLAVMASGKSRKVEPLPLPEPTPSPVAEVKAAPAPLVPSKVHVGPVRSGQQLYAAGTSLVILGSVSQ
GAEVIADDSIHIYGALRGRAIAGAKGNTQARIYCQQLQAELLSIAGTFQLSDALPAGLIQQPVHVRLDNEQLRIDHIK

Sequences:

>Translated_238_residues
MVERDNELKGTTFTISVLHISDGKPERIRQLLAAKVAQAPQFFNCAPLVINVERLADIPDFDQLKGLVESEDFVLVGITG
ARDEAMKTAAKAAGLAVMASGKSRKVEPLPLPEPTPSPVAEVKAAPAPLVPSKVHVGPVRSGQQLYAAGTSLVILGSVSQ
GAEVIADDSIHIYGALRGRAIAGAKGNTQARIYCQQLQAELLSIAGTFQLSDALPAGLIQQPVHVRLDNEQLRIDHIK
>Mature_238_residues
MVERDNELKGTTFTISVLHISDGKPERIRQLLAAKVAQAPQFFNCAPLVINVERLADIPDFDQLKGLVESEDFVLVGITG
ARDEAMKTAAKAAGLAVMASGKSRKVEPLPLPEPTPSPVAEVKAAPAPLVPSKVHVGPVRSGQQLYAAGTSLVILGSVSQ
GAEVIADDSIHIYGALRGRAIAGAKGNTQARIYCQQLQAELLSIAGTFQLSDALPAGLIQQPVHVRLDNEQLRIDHIK

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization [H]

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family [H]

Homologues:

Organism=Escherichia coli, GI1787424, Length=228, Percent_Identity=38.1578947368421, Blast_Score=172, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR007874
- InterPro:   IPR005526 [H]

Pfam domain/function: PF03775 MinC_C; PF05209 MinC_N [H]

EC number: NA

Molecular weight: Translated: 25275; Mature: 25275

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVERDNELKGTTFTISVLHISDGKPERIRQLLAAKVAQAPQFFNCAPLVINVERLADIPD
CCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHCCCCC
FDQLKGLVESEDFVLVGITGARDEAMKTAAKAAGLAVMASGKSRKVEPLPLPEPTPSPVA
HHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCHH
EVKAAPAPLVPSKVHVGPVRSGQQLYAAGTSLVILGSVSQGAEVIADDSIHIYGALRGRA
HHCCCCCCCCCCCEEECCCCCCCEEEECCCEEEEEECCCCCCEEEECCCEEEEEEECCCE
IAGAKGNTQARIYCQQLQAELLSIAGTFQLSDALPAGLIQQPVHVRLDNEQLRIDHIK
EECCCCCCHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHCCCEEEEECCCEEEEEECC
>Mature Secondary Structure
MVERDNELKGTTFTISVLHISDGKPERIRQLLAAKVAQAPQFFNCAPLVINVERLADIPD
CCCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHCCCCC
FDQLKGLVESEDFVLVGITGARDEAMKTAAKAAGLAVMASGKSRKVEPLPLPEPTPSPVA
HHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCHH
EVKAAPAPLVPSKVHVGPVRSGQQLYAAGTSLVILGSVSQGAEVIADDSIHIYGALRGRA
HHCCCCCCCCCCCEEECCCCCCCEEEECCCEEEEEECCCCCCEEEECCCEEEEEEECCCE
IAGAKGNTQARIYCQQLQAELLSIAGTFQLSDALPAGLIQQPVHVRLDNEQLRIDHIK
EECCCCCCHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHCCCEEEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA