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The map label for this gene is benK [H]

Identifier: 145297013

GI number: 145297013

Start: 3230791

End: 3232092

Strand: Direct

Name: benK [H]

Synonym: cgR_2912

Alternate gene names: 145297013

Gene position: 3230791-3232092 (Clockwise)

Preceding gene: 145297007

Following gene: 145297014

Centisome position: 97.48

GC content: 56.99

Gene sequence:

>1302_bases
ATGACAGAGCCAACTCTCGGAGCATCGAATAGCTCCCAAACAATTGAAAACAAAGGCCTCACCATCTTGGGCATCAGCGG
CCGACGCTTGGCTGCGGTGCTCATTGGCTGGTTTTTTGTCATTTTCGACGGCTACGACCTCATTGTGTACGGCACCGTCC
AATCAGCCTTGGCTAAGGAGTGGAACTTAAGCTCTGCAACGCTGGGCACCATCGGCTCTACCGCGTTCTTTGGCATGGCG
ATCGGCGCTGTGTTCATTGGTCGACTGTCAGACCGCGTGGGCCGAAAAGCAGCGGTGATTGGATCCGTGCTGATTCTCTC
TGTCTTCACCATGCTGTGTGCATTTGCTCCAAACCCATGGGTGTTCGGCGCTTTCCGTTTCATCGCAGGCCTTGGTCTGG
GCGGCTTGGTGCCTTCAGTTAATGCGATGACCTCTGATCTGGTTCCACGTAAGACCATGTCAGCGTGGGCAACTGTCATG
ATGTCTGGCGTTCCCATTGGTGGTTCCATCGCGGCTGTGCTGGCTCTTGCTGTTGTTCCTTCCTCAGAGGAGTGGGGCTG
GCGCTTCATGTTCCTCATCGCGTTGATCCCACTGGTTGTCGGCCTGCCGATCGCCATGAAGGTCATTCCTTCCGATAAGG
CCATCAAGGCGGATCACGAAATCCGAGAAGGCCACGATGAGCCAGCAGGTTTCAAGGATCTACTTGTCGATCGCTACCGC
TGGATCTCCATTTGGTTCGCGCTCGCCACATTTGTCACCCTGCTCGCGTGGTACGGCCTAGGCACATGGTTGCCTCGCCT
CATGGAAACTGCAGGCTATGAGTTCGGCCATGCATTGATGTTCACCCTGGCTCTGAACCTCGGTGCAGTGATCGGATCCG
TGGTTACTGCGTGGGCCGGCGATCGTTTCGGGCCAATCCGTTCCGGTGTCATCGCTGCAGGTATCGCCGGTATTGCACTG
CTCCTGCTGCTCACTTACCCGCCTGTCACCGCAGTTTATGTCATTCTCATTTTGGCTGGCGTGGGCACCCACGGCACTCA
GATCCTCATCATTGCAGCTGTCGCCAACTTCTACCCAAGCAACTTGCGTGGCACGGCACTGGGCTGGGCGTTAGGTGTGG
GCCGCATCGGTGCGGTTGTGGCCCCGCAGCTCGCTGGTCTGCTGCTCGCATGGAACTTGGGCGTGAACTCCAACTTCATC
ATGTTCGGCGCCGCTGCGTTGCTCTCTGCGCTGGCTCTCAGCGTGTTGCTGCGCCTGCAAAAAACCTACAGCGTCACCCA
CAAAGTCGAAATCCAAGGCTAA

Upstream 100 bases:

>100_bases
CATAATCACTCTTTCCAGATAGCGGAATACCTTTGATTGTAACTTGTCTCACCTCGATTATGTGTTTATGACATCACACG
CACCAGAATCGGGAGGACTT

Downstream 100 bases:

>100_bases
ACCCCCTTTTTCAACTCACAGTTAGGAAACTTCACCCATGTCTCTTCCACATTCTGATGAACTCCGCGGCCAAAAGATCA
TTATTTCCGGTGGCGGAATT

Product: hypothetical protein

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MTEPTLGASNSSQTIENKGLTILGISGRRLAAVLIGWFFVIFDGYDLIVYGTVQSALAKEWNLSSATLGTIGSTAFFGMA
IGAVFIGRLSDRVGRKAAVIGSVLILSVFTMLCAFAPNPWVFGAFRFIAGLGLGGLVPSVNAMTSDLVPRKTMSAWATVM
MSGVPIGGSIAAVLALAVVPSSEEWGWRFMFLIALIPLVVGLPIAMKVIPSDKAIKADHEIREGHDEPAGFKDLLVDRYR
WISIWFALATFVTLLAWYGLGTWLPRLMETAGYEFGHALMFTLALNLGAVIGSVVTAWAGDRFGPIRSGVIAAGIAGIAL
LLLLTYPPVTAVYVILILAGVGTHGTQILIIAAVANFYPSNLRGTALGWALGVGRIGAVVAPQLAGLLLAWNLGVNSNFI
MFGAAALLSALALSVLLRLQKTYSVTHKVEIQG

Sequences:

>Translated_433_residues
MTEPTLGASNSSQTIENKGLTILGISGRRLAAVLIGWFFVIFDGYDLIVYGTVQSALAKEWNLSSATLGTIGSTAFFGMA
IGAVFIGRLSDRVGRKAAVIGSVLILSVFTMLCAFAPNPWVFGAFRFIAGLGLGGLVPSVNAMTSDLVPRKTMSAWATVM
MSGVPIGGSIAAVLALAVVPSSEEWGWRFMFLIALIPLVVGLPIAMKVIPSDKAIKADHEIREGHDEPAGFKDLLVDRYR
WISIWFALATFVTLLAWYGLGTWLPRLMETAGYEFGHALMFTLALNLGAVIGSVVTAWAGDRFGPIRSGVIAAGIAGIAL
LLLLTYPPVTAVYVILILAGVGTHGTQILIIAAVANFYPSNLRGTALGWALGVGRIGAVVAPQLAGLLLAWNLGVNSNFI
MFGAAALLSALALSVLLRLQKTYSVTHKVEIQG
>Mature_432_residues
TEPTLGASNSSQTIENKGLTILGISGRRLAAVLIGWFFVIFDGYDLIVYGTVQSALAKEWNLSSATLGTIGSTAFFGMAI
GAVFIGRLSDRVGRKAAVIGSVLILSVFTMLCAFAPNPWVFGAFRFIAGLGLGGLVPSVNAMTSDLVPRKTMSAWATVMM
SGVPIGGSIAAVLALAVVPSSEEWGWRFMFLIALIPLVVGLPIAMKVIPSDKAIKADHEIREGHDEPAGFKDLLVDRYRW
ISIWFALATFVTLLAWYGLGTWLPRLMETAGYEFGHALMFTLALNLGAVIGSVVTAWAGDRFGPIRSGVIAAGIAGIALL
LLLTYPPVTAVYVILILAGVGTHGTQILIIAAVANFYPSNLRGTALGWALGVGRIGAVVAPQLAGLLLAWNLGVNSNFIM
FGAAALLSALALSVLLRLQKTYSVTHKVEIQG

Specific function: Probable uptake of benzoate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24308167, Length=419, Percent_Identity=23.8663484486874, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI87081723, Length=372, Percent_Identity=29.8387096774194, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI87082404, Length=405, Percent_Identity=23.7037037037037, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI87082231, Length=183, Percent_Identity=27.8688524590164, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790550, Length=392, Percent_Identity=24.234693877551, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082159, Length=392, Percent_Identity=24.7448979591837, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1788074, Length=386, Percent_Identity=23.8341968911917, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI32564663, Length=467, Percent_Identity=22.6980728051392, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19922874, Length=400, Percent_Identity=23, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45737; Mature: 45605

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPTLGASNSSQTIENKGLTILGISGRRLAAVLIGWFFVIFDGYDLIVYGTVQSALAKE
CCCCCCCCCCCCCHHHHCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHH
WNLSSATLGTIGSTAFFGMAIGAVFIGRLSDRVGRKAAVIGSVLILSVFTMLCAFAPNPW
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCH
VFGAFRFIAGLGLGGLVPSVNAMTSDLVPRKTMSAWATVMMSGVPIGGSIAAVLALAVVP
HHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC
SSEEWGWRFMFLIALIPLVVGLPIAMKVIPSDKAIKADHEIREGHDEPAGFKDLLVDRYR
CCCCCCHHHHHHHHHHHHHHCCCHHEEECCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHH
WISIWFALATFVTLLAWYGLGTWLPRLMETAGYEFGHALMFTLALNLGAVIGSVVTAWAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
DRFGPIRSGVIAAGIAGIALLLLLTYPPVTAVYVILILAGVGTHGTQILIIAAVANFYPS
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEHHHHHHHHCCC
NLRGTALGWALGVGRIGAVVAPQLAGLLLAWNLGVNSNFIMFGAAALLSALALSVLLRLQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
KTYSVTHKVEIQG
HHHCCEEEEEECC
>Mature Secondary Structure 
TEPTLGASNSSQTIENKGLTILGISGRRLAAVLIGWFFVIFDGYDLIVYGTVQSALAKE
CCCCCCCCCCCCHHHHCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHH
WNLSSATLGTIGSTAFFGMAIGAVFIGRLSDRVGRKAAVIGSVLILSVFTMLCAFAPNPW
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCH
VFGAFRFIAGLGLGGLVPSVNAMTSDLVPRKTMSAWATVMMSGVPIGGSIAAVLALAVVP
HHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC
SSEEWGWRFMFLIALIPLVVGLPIAMKVIPSDKAIKADHEIREGHDEPAGFKDLLVDRYR
CCCCCCHHHHHHHHHHHHHHCCCHHEEECCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHH
WISIWFALATFVTLLAWYGLGTWLPRLMETAGYEFGHALMFTLALNLGAVIGSVVTAWAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
DRFGPIRSGVIAAGIAGIALLLLLTYPPVTAVYVILILAGVGTHGTQILIIAAVANFYPS
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEHHHHHHHHCCC
NLRGTALGWALGVGRIGAVVAPQLAGLLLAWNLGVNSNFIMFGAAALLSALALSVLLRLQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
KTYSVTHKVEIQG
HHHCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9294456 [H]