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The map label for this gene is rkpK [H]

Identifier: 145296834

GI number: 145296834

Start: 3029223

End: 3030542

Strand: Reverse

Name: rkpK [H]

Synonym: cgR_2736

Alternate gene names: 145296834

Gene position: 3030542-3029223 (Counterclockwise)

Preceding gene: 145296835

Following gene: 145296827

Centisome position: 91.44

GC content: 57.95

Gene sequence:

>1320_bases
ATGCGGATGACAGTGATTGGTACGGGTTACCTTGGCGCTACGCACGCGGCCTGCATGGCTGAGCTTGGCCATGAGGTTCT
TGGTGTTGATGTCGATGAGGCAAAGATTGCGTCGTTGAAGGACAGCAAGGTCCCATTTTTTGAGCCGGGTTTACCTGAGG
TTTTGGAGCGCAATCTGGAAAATGGCCGCCTGAACTTCACTACTGATTATGCGGAGGCTGCGGCTTTCGCGCAGGTGCAT
TTCTTGGGCGTGGGTACTCCTCAGCAGAAGGGTACTTATGCGGCGGATCTGACGTATGTTCGTCAGGTTGTTGAGGATTT
GGTGCCGCTGCTTGAGGGCGAGCACATTATTTTCGGCAAGTCTACGGTTCCGGTTGGTACTGCTGAGCAGTTGCAGGAGC
TTGCTGATTCTCTGGTCAAGCCTGGTTCGCACGTGGAGATCGCGTGGAATCCGGAGTTTTTGCGCGAGGGTTACGCGGTA
AAAGACACCATCACCCCGGACCGTATTGTGGTTGGTGTGCGTGCTGGTTCAGAGGCTGCAGATGTTGCCCGCGAGGTTTA
CGCCACCGCGATTGCTGCCGATACCCCATTTTTGGTGACTGATCTTGCTACCGCTGAGCTGGTGAAAGTTTCCGCGAATG
CGTTCTTGGCCACCAAGATTTCCTTCATCAATGCGGTCGCTGAGATTTGTGAGCAGACCGGCGCCGATGTGGTTGCGCTT
GCGGATGCCATCGGTCACGACGATCGTATCGGCCGAAGGTTCTTAGGCGCGGGCCTGGGATTCGGTGGCGGTTGCTTGCC
TAAGGATATCCGCGCATTCATGGCGCGCGCGGGCGAATTGGGCGCTGACCAGGCACTTACCTTCCTGCGTGAGGTCGATT
CCATCAATATGCGCCGCCGTGACCGCGTGGTGCAGCTGGCCAAAGAGATGTGTGGCGGTTCGCTGCTGGGCAAGCGCATC
ACGGTACTCGGCGCCGCATTCAAGCCTAACTCCGATGACGTCCGCGATTCTCCGGCGTTGTCGGTCGCGGGTTCGCTGTC
GCTCCAGGGTGCCGCGGTCTCGGTCTACGACCCGGAAGCTATGGACAACGCTCGACGCGTCTTCCCGACGCTCAGCTATG
CGTCCAGCACTAAAGAGGCGCTTATCGACGCCCACCTCGTCGTTCTTGCCACTGAATGGCAAGAATTCCGCGACCTTGAC
CCCCAAGTGGCGGGAGGGGTCGTCGAGAAGCGCGCTATTATTGATGGCCGAAACGTCCTCGATGTTGCCAAATGGAAGGC
CGCCGGTTGGGAAATGGAAGCGCTCGGCCGTAACCTTTAG

Upstream 100 bases:

>100_bases
TTCCCCAACAAGTAAGCAATCATGTGTTCCGGTCGCGGGCTGTATCAAAACGTGTTGAGATAATCTCCAGTCCACTCTTC
ATTGAAAGGAATCACCCTAC

Downstream 100 bases:

>100_bases
TGGCGGTGGATCAGGCGGGGCTTGCCATCATCTGGGGCGGGCTCATCGCCGGGTACCGTCCATGCGGCGATCAGCGTTGT
GATCGGCACCGCCAGCGTCA

Product: hypothetical protein

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MRMTVIGTGYLGATHAACMAELGHEVLGVDVDEAKIASLKDSKVPFFEPGLPEVLERNLENGRLNFTTDYAEAAAFAQVH
FLGVGTPQQKGTYAADLTYVRQVVEDLVPLLEGEHIIFGKSTVPVGTAEQLQELADSLVKPGSHVEIAWNPEFLREGYAV
KDTITPDRIVVGVRAGSEAADVAREVYATAIAADTPFLVTDLATAELVKVSANAFLATKISFINAVAEICEQTGADVVAL
ADAIGHDDRIGRRFLGAGLGFGGGCLPKDIRAFMARAGELGADQALTFLREVDSINMRRRDRVVQLAKEMCGGSLLGKRI
TVLGAAFKPNSDDVRDSPALSVAGSLSLQGAAVSVYDPEAMDNARRVFPTLSYASSTKEALIDAHLVVLATEWQEFRDLD
PQVAGGVVEKRAIIDGRNVLDVAKWKAAGWEMEALGRNL

Sequences:

>Translated_439_residues
MRMTVIGTGYLGATHAACMAELGHEVLGVDVDEAKIASLKDSKVPFFEPGLPEVLERNLENGRLNFTTDYAEAAAFAQVH
FLGVGTPQQKGTYAADLTYVRQVVEDLVPLLEGEHIIFGKSTVPVGTAEQLQELADSLVKPGSHVEIAWNPEFLREGYAV
KDTITPDRIVVGVRAGSEAADVAREVYATAIAADTPFLVTDLATAELVKVSANAFLATKISFINAVAEICEQTGADVVAL
ADAIGHDDRIGRRFLGAGLGFGGGCLPKDIRAFMARAGELGADQALTFLREVDSINMRRRDRVVQLAKEMCGGSLLGKRI
TVLGAAFKPNSDDVRDSPALSVAGSLSLQGAAVSVYDPEAMDNARRVFPTLSYASSTKEALIDAHLVVLATEWQEFRDLD
PQVAGGVVEKRAIIDGRNVLDVAKWKAAGWEMEALGRNL
>Mature_439_residues
MRMTVIGTGYLGATHAACMAELGHEVLGVDVDEAKIASLKDSKVPFFEPGLPEVLERNLENGRLNFTTDYAEAAAFAQVH
FLGVGTPQQKGTYAADLTYVRQVVEDLVPLLEGEHIIFGKSTVPVGTAEQLQELADSLVKPGSHVEIAWNPEFLREGYAV
KDTITPDRIVVGVRAGSEAADVAREVYATAIAADTPFLVTDLATAELVKVSANAFLATKISFINAVAEICEQTGADVVAL
ADAIGHDDRIGRRFLGAGLGFGGGCLPKDIRAFMARAGELGADQALTFLREVDSINMRRRDRVVQLAKEMCGGSLLGKRI
TVLGAAFKPNSDDVRDSPALSVAGSLSLQGAAVSVYDPEAMDNARRVFPTLSYASSTKEALIDAHLVVLATEWQEFRDLD
PQVAGGVVEKRAIIDGRNVLDVAKWKAAGWEMEALGRNL

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=467, Percent_Identity=32.9764453961456, Blast_Score=243, Evalue=3e-64,
Organism=Homo sapiens, GI296040438, Length=367, Percent_Identity=33.2425068119891, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI296040443, Length=316, Percent_Identity=32.5949367088608, Blast_Score=169, Evalue=4e-42,
Organism=Escherichia coli, GI48994968, Length=433, Percent_Identity=26.7898383371824, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1788340, Length=361, Percent_Identity=27.4238227146814, Blast_Score=138, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17560350, Length=460, Percent_Identity=33.695652173913, Blast_Score=225, Evalue=4e-59,
Organism=Drosophila melanogaster, GI17136908, Length=462, Percent_Identity=33.982683982684, Blast_Score=255, Evalue=5e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 46953; Mature: 46953

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMTVIGTGYLGATHAACMAELGHEVLGVDVDEAKIASLKDSKVPFFEPGLPEVLERNLE
CEEEEEECCCCHHHHHHHHHHHCHHHCCCCCCHHHHHHCCCCCCCCCCCCCHHHHHCCCC
NGRLNFTTDYAEAAAFAQVHFLGVGTPQQKGTYAADLTYVRQVVEDLVPLLEGEHIIFGK
CCCEEEEECHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEC
STVPVGTAEQLQELADSLVKPGSHVEIAWNPEFLREGYAVKDTITPDRIVVGVRAGSEAA
CCCCCCCHHHHHHHHHHHHCCCCEEEEEECHHHHHCCCCEECCCCCCEEEEEEECCCHHH
DVAREVYATAIAADTPFLVTDLATAELVKVSANAFLATKISFINAVAEICEQTGADVVAL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEH
ADAIGHDDRIGRRFLGAGLGFGGGCLPKDIRAFMARAGELGADQALTFLREVDSINMRRR
HHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHH
DRVVQLAKEMCGGSLLGKRITVLGAAFKPNSDDVRDSPALSVAGSLSLQGAAVSVYDPEA
HHHHHHHHHHCCCHHHHCEEEEEEEECCCCCCCCCCCCCCEEECCCEECCCEEEEECCHH
MDNARRVFPTLSYASSTKEALIDAHLVVLATEWQEFRDLDPQVAGGVVEKRAIIDGRNVL
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHCCCHHHHCCHHHHHHHCCCCCHH
DVAKWKAAGWEMEALGRNL
HHHHHHCCCCCHHHHCCCC
>Mature Secondary Structure
MRMTVIGTGYLGATHAACMAELGHEVLGVDVDEAKIASLKDSKVPFFEPGLPEVLERNLE
CEEEEEECCCCHHHHHHHHHHHCHHHCCCCCCHHHHHHCCCCCCCCCCCCCHHHHHCCCC
NGRLNFTTDYAEAAAFAQVHFLGVGTPQQKGTYAADLTYVRQVVEDLVPLLEGEHIIFGK
CCCEEEEECHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEC
STVPVGTAEQLQELADSLVKPGSHVEIAWNPEFLREGYAVKDTITPDRIVVGVRAGSEAA
CCCCCCCHHHHHHHHHHHHCCCCEEEEEECHHHHHCCCCEECCCCCCEEEEEEECCCHHH
DVAREVYATAIAADTPFLVTDLATAELVKVSANAFLATKISFINAVAEICEQTGADVVAL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEH
ADAIGHDDRIGRRFLGAGLGFGGGCLPKDIRAFMARAGELGADQALTFLREVDSINMRRR
HHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHH
DRVVQLAKEMCGGSLLGKRITVLGAAFKPNSDDVRDSPALSVAGSLSLQGAAVSVYDPEA
HHHHHHHHHHCCCHHHHCEEEEEEEECCCCCCCCCCCCCCEEECCCEECCCEEEEECCHH
MDNARRVFPTLSYASSTKEALIDAHLVVLATEWQEFRDLDPQVAGGVVEKRAIIDGRNVL
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHCCCHHHHCCHHHHHHHCCCCCHH
DVAKWKAAGWEMEALGRNL
HHHHHHCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9765575; 11481430 [H]