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The map label for this gene is tag [H]

Identifier: 145296820

GI number: 145296820

Start: 3014215

End: 3014805

Strand: Direct

Name: tag [H]

Synonym: cgR_2723

Alternate gene names: 145296820

Gene position: 3014215-3014805 (Clockwise)

Preceding gene: 145296819

Following gene: 145296822

Centisome position: 90.95

GC content: 53.47

Gene sequence:

>591_bases
ATGAATTCATTAATCGTTGGCGAGGACGGCCTCAGTCGCCCGAGTTGGGCTGCGCAAGATCCTCTGATGCGCGATTATTA
CGACACCGAGTGGGGCATGCCGATTCGCGATGAGCAGGGATTATTCGAAAGAATCAGTCTAGAAGCTTTTCAATCCGGGC
TGTCCTGGGCGACGATTTTGCGCAAGCGCGATAATTTCCGCGCAGCTTTCTCTCAATTCGATCCTGAATTAGTCGCAAAA
TTCACCGACGCTGACATCGAACGCCTCATGGAGGATGCCGGCATCGTGCGCAACAAACGCAAGATTTTAGCCACCATCAA
CAATGCCAAAGCCACCCTTCCATTGCGTGAGAAGGGTGGCTTGGTGGATTTCGTGTGGAGTTTCAAACCTGCCAAAACCC
CACAACCGGAGACCCTGGAGGAAATCCCGACGCAGTCGCCGGAATCAGTTGCGCTGTCAAAAGCGCTGAAGAAGGAAGGT
TTTTCCTTCGTTGGTCCCACCACGATGTTTGCCCTCATGGAGGCCATAGGGATCATCGATACCCATTTGGTGGGCAGCCA
TCGCCGTGGAAGTTCTGGGGTGTGGGCTTAG

Upstream 100 bases:

>100_bases
CACAAATTGAAATGATGCTCAGGGAACAATTGCGCAAGGCGGGTCGGTTGCCTAAAAATATTGGGAACATTCCGAAACCA
GGCCGACCCAAGGAGAATCC

Downstream 100 bases:

>100_bases
GAAATCAGCCAGTCGTTTGGTGAGAACAGCTCGAAGTTCACATCGCGTGGCTGCTCTTCCAACGCTTCAATCTGGCCACG
GACATTCTTCAAGAATTCCA

Product: hypothetical protein

Products: NA

Alternate protein names: 3-methyladenine-DNA glycosylase I, constitutive; TAG I; DNA-3-methyladenine glycosidase I; DNA-3-methyladenine glycosylase I [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MNSLIVGEDGLSRPSWAAQDPLMRDYYDTEWGMPIRDEQGLFERISLEAFQSGLSWATILRKRDNFRAAFSQFDPELVAK
FTDADIERLMEDAGIVRNKRKILATINNAKATLPLREKGGLVDFVWSFKPAKTPQPETLEEIPTQSPESVALSKALKKEG
FSFVGPTTMFALMEAIGIIDTHLVGSHRRGSSGVWA

Sequences:

>Translated_196_residues
MNSLIVGEDGLSRPSWAAQDPLMRDYYDTEWGMPIRDEQGLFERISLEAFQSGLSWATILRKRDNFRAAFSQFDPELVAK
FTDADIERLMEDAGIVRNKRKILATINNAKATLPLREKGGLVDFVWSFKPAKTPQPETLEEIPTQSPESVALSKALKKEG
FSFVGPTTMFALMEAIGIIDTHLVGSHRRGSSGVWA
>Mature_196_residues
MNSLIVGEDGLSRPSWAAQDPLMRDYYDTEWGMPIRDEQGLFERISLEAFQSGLSWATILRKRDNFRAAFSQFDPELVAK
FTDADIERLMEDAGIVRNKRKILATINNAKATLPLREKGGLVDFVWSFKPAKTPQPETLEEIPTQSPESVALSKALKKEG
FSFVGPTTMFALMEAIGIIDTHLVGSHRRGSSGVWA

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789971, Length=179, Percent_Identity=50.8379888268156, Blast_Score=190, Evalue=5e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005019
- InterPro:   IPR011257
- InterPro:   IPR004597 [H]

Pfam domain/function: PF03352 Adenine_glyco [H]

EC number: =3.2.2.20 [H]

Molecular weight: Translated: 21905; Mature: 21905

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSLIVGEDGLSRPSWAAQDPLMRDYYDTEWGMPIRDEQGLFERISLEAFQSGLSWATIL
CCCEEECCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHH
RKRDNFRAAFSQFDPELVAKFTDADIERLMEDAGIVRNKRKILATINNAKATLPLREKGG
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCEEECCCHHCCC
LVDFVWSFKPAKTPQPETLEEIPTQSPESVALSKALKKEGFSFVGPTTMFALMEAIGIID
EEEEEECCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
THLVGSHRRGSSGVWA
HHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNSLIVGEDGLSRPSWAAQDPLMRDYYDTEWGMPIRDEQGLFERISLEAFQSGLSWATIL
CCCEEECCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHH
RKRDNFRAAFSQFDPELVAKFTDADIERLMEDAGIVRNKRKILATINNAKATLPLREKGG
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCEEECCCHHCCC
LVDFVWSFKPAKTPQPETLEEIPTQSPESVALSKALKKEGFSFVGPTTMFALMEAIGIID
EEEEEECCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
THLVGSHRRGSSGVWA
HHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3536912; 3520491; 8041620; 9278503 [H]