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The map label for this gene is fprA [H]

Identifier: 145296753

GI number: 145296753

Start: 2942106

End: 2943473

Strand: Direct

Name: fprA [H]

Synonym: cgR_2657

Alternate gene names: 145296753

Gene position: 2942106-2943473 (Clockwise)

Preceding gene: 145296750

Following gene: 145296754

Centisome position: 88.77

GC content: 55.34

Gene sequence:

>1368_bases
ATGTCTCGCCCTTTGCGTGTTGCCGTTGTCGGTGCAGGTCCAGCAGGAATCTACGCGTCTGATTTGTTGATGAAATCCGA
CACGGACGTGCAGATTGATCTTTTTGAACGCATGCCAGCGCCTTTCGGTTTGATCCGTTATGGTGTTGCGCCTGATCACC
CTCGCATCAAGGGCATCGTGAAGTCCCTGCACAATGTGATGGACAAGGAGCAGCTGCGTTTCTTGGGCAACATTGAGGTC
GGCAAGGACATCACTGTTGAGGAGTTGCGTGAGTTTTATGACGCGATCGTGTTCTCCACTGGCGCTACTGGCGACCAGGA
TCTTCGGGTTCCAGGTTCTGATCTGGAAGGTTCGTGGGGCGCTGGCGAGTTCGTTGGTTTCTATGATGGCAACCCGAACT
TTGAACGCAACTGGGATCTTTCTGCTGAGAAGGTAGCGGTTGTTGGTGTCGGTAACGTGGCGTTGGACGTTGCTCGTATT
TTGGCGAAGACTGGCGATGAGCTGCTAGTTACTGAAATCCCTGACAATGTCTATGAGAGCTTGGCTAAGAATCAGGCTAA
GGAAGTGCACGTTTTTGGTCGTCGTGGACCTGCTCAGGCGAAGTTCACTCCGTTGGAGCTGAAGGAACTTGATCATTCCG
ACACCATCGAGGTGATCGTGAACCCTGAGGACATTGATTACGATGCAGCTTCGGAGCAGGCTCGTCGTGATTCCAAGTCT
CAGGACCTCGTGTGCCAGACTTTGGAAAGCTACGCGATGCGCGATCCTAAGGGCGCTCCTCACAAGCTGTTCATTCACTT
CTTTGAGTCCCCAGTGGAGATCCTCGGTGAAGACGGCAAGGTTGTTGGCCTCAAGACTGAGCGCACTCAGCTGGATGGTA
ACGGTGGCGTGACTGGTACCGGCGAGTTCAAGACCTGGGATGTGCAGTCAGTTTACCGCGCGGTGGGTTACCGTTCTGAT
GCGATCGAGGGTGTTCCATTTGATGATGAGCGCGCGGTTGTCCCCAACGACGGCGGCCACATCATCGATCCTGAGGTCGG
CTCCCCCATCACTGGCCTGTACGCCACTGGCTGGATCAAGCGTGGCCCAATTGGACTGATCGGCAACACCAAGTCCGACG
CCAAGGAAACCACTGAGATGCTGCTTGCTGATCACGCTGCTGGTTCTTTGCCTGCGCCTGCGAAGCCTGAGTTGGAGTCC
ATCATTGAGTTCCTCGATGAGCGCAAGGTTGCGTTCACCACGTGGGATGGCTGGCACCTGCTGGATGCTGCGGAGCGCGC
GCTGGGTGAGCCTGAGGGCCGCGAGCGCAAGAAGATCGTTGAGTGGAATGACATGGTGCGCCATGCTCGACCAGAATACG
ACATCTAA

Upstream 100 bases:

>100_bases
CACCATTAGCAGTCGCACCCCGATAGGAGTCGAATCTACTAGTGGAACCCCGCTCACATACTCCACATTTTTAGAACCCC
TTTAAGGAATCGAACTTTAT

Downstream 100 bases:

>100_bases
AGTCGCTTAAAGCCTCAAAAAAGGGCGCTGTTGGAGGTTAATCCACAGCGCCCTGTGTGCACTCTACTAGTGAATATCCG
GTGAATGCTCGTCCCTCGAC

Product: hypothetical protein

Products: NA

Alternate protein names: NFR [H]

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MSRPLRVAVVGAGPAGIYASDLLMKSDTDVQIDLFERMPAPFGLIRYGVAPDHPRIKGIVKSLHNVMDKEQLRFLGNIEV
GKDITVEELREFYDAIVFSTGATGDQDLRVPGSDLEGSWGAGEFVGFYDGNPNFERNWDLSAEKVAVVGVGNVALDVARI
LAKTGDELLVTEIPDNVYESLAKNQAKEVHVFGRRGPAQAKFTPLELKELDHSDTIEVIVNPEDIDYDAASEQARRDSKS
QDLVCQTLESYAMRDPKGAPHKLFIHFFESPVEILGEDGKVVGLKTERTQLDGNGGVTGTGEFKTWDVQSVYRAVGYRSD
AIEGVPFDDERAVVPNDGGHIIDPEVGSPITGLYATGWIKRGPIGLIGNTKSDAKETTEMLLADHAAGSLPAPAKPELES
IIEFLDERKVAFTTWDGWHLLDAAERALGEPEGRERKKIVEWNDMVRHARPEYDI

Sequences:

>Translated_455_residues
MSRPLRVAVVGAGPAGIYASDLLMKSDTDVQIDLFERMPAPFGLIRYGVAPDHPRIKGIVKSLHNVMDKEQLRFLGNIEV
GKDITVEELREFYDAIVFSTGATGDQDLRVPGSDLEGSWGAGEFVGFYDGNPNFERNWDLSAEKVAVVGVGNVALDVARI
LAKTGDELLVTEIPDNVYESLAKNQAKEVHVFGRRGPAQAKFTPLELKELDHSDTIEVIVNPEDIDYDAASEQARRDSKS
QDLVCQTLESYAMRDPKGAPHKLFIHFFESPVEILGEDGKVVGLKTERTQLDGNGGVTGTGEFKTWDVQSVYRAVGYRSD
AIEGVPFDDERAVVPNDGGHIIDPEVGSPITGLYATGWIKRGPIGLIGNTKSDAKETTEMLLADHAAGSLPAPAKPELES
IIEFLDERKVAFTTWDGWHLLDAAERALGEPEGRERKKIVEWNDMVRHARPEYDI
>Mature_454_residues
SRPLRVAVVGAGPAGIYASDLLMKSDTDVQIDLFERMPAPFGLIRYGVAPDHPRIKGIVKSLHNVMDKEQLRFLGNIEVG
KDITVEELREFYDAIVFSTGATGDQDLRVPGSDLEGSWGAGEFVGFYDGNPNFERNWDLSAEKVAVVGVGNVALDVARIL
AKTGDELLVTEIPDNVYESLAKNQAKEVHVFGRRGPAQAKFTPLELKELDHSDTIEVIVNPEDIDYDAASEQARRDSKSQ
DLVCQTLESYAMRDPKGAPHKLFIHFFESPVEILGEDGKVVGLKTERTQLDGNGGVTGTGEFKTWDVQSVYRAVGYRSDA
IEGVPFDDERAVVPNDGGHIIDPEVGSPITGLYATGWIKRGPIGLIGNTKSDAKETTEMLLADHAAGSLPAPAKPELESI
IEFLDERKVAFTTWDGWHLLDAAERALGEPEGRERKKIVEWNDMVRHARPEYDI

Specific function: May serve as electron transfer protein and supply electrons to P450 systems [H]

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ferredoxin--NADP reductase type 1 family [H]

Homologues:

Organism=Homo sapiens, GI111118981, Length=457, Percent_Identity=36.1050328227571, Blast_Score=275, Evalue=8e-74,
Organism=Homo sapiens, GI111118983, Length=463, Percent_Identity=35.6371490280778, Blast_Score=269, Evalue=3e-72,
Organism=Escherichia coli, GI87082180, Length=163, Percent_Identity=30.6748466257669, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788811, Length=167, Percent_Identity=28.7425149700599, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789606, Length=168, Percent_Identity=27.3809523809524, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17543860, Length=442, Percent_Identity=31.2217194570136, Blast_Score=224, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI17570289, Length=156, Percent_Identity=32.6923076923077, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320584, Length=482, Percent_Identity=28.8381742738589, Blast_Score=176, Evalue=5e-45,
Organism=Saccharomyces cerevisiae, GI6320030, Length=158, Percent_Identity=31.0126582278481, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17137178, Length=450, Percent_Identity=33.5555555555556, Blast_Score=238, Evalue=7e-63,
Organism=Drosophila melanogaster, GI28574881, Length=168, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24665539, Length=168, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24665547, Length=168, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24665543, Length=168, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR021163
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07992 Pyr_redox_2 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 50040; Mature: 49908

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPLRVAVVGAGPAGIYASDLLMKSDTDVQIDLFERMPAPFGLIRYGVAPDHPRIKGIV
CCCCEEEEEEECCCCCHHHHHHEEECCCCEEEEHHHHCCCCHHHEEECCCCCCHHHHHHH
KSLHNVMDKEQLRFLGNIEVGKDITVEELREFYDAIVFSTGATGDQDLRVPGSDLEGSWG
HHHHHHHCHHHHHHHCCCCCCCCCCHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCC
AGEFVGFYDGNPNFERNWDLSAEKVAVVGVGNVALDVARILAKTGDELLVTEIPDNVYES
CCCEEEEECCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCEEEECCCHHHHHH
LAKNQAKEVHVFGRRGPAQAKFTPLELKELDHSDTIEVIVNPEDIDYDAASEQARRDSKS
HHHCCCCEEEEECCCCCCCCCCCCHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHCCCH
QDLVCQTLESYAMRDPKGAPHKLFIHFFESPVEILGEDGKVVGLKTERTQLDGNGGVTGT
HHHHHHHHHHHHHCCCCCCCCEEEEEEHHCHHHHCCCCCCEEEEEECCEEECCCCCCCCC
GEFKTWDVQSVYRAVGYRSDAIEGVPFDDERAVVPNDGGHIIDPEVGSPITGLYATGWIK
CCCEECCHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCEEECCCCCCCCCCHHHHCCCC
RGPIGLIGNTKSDAKETTEMLLADHAAGSLPAPAKPELESIIEFLDERKVAFTTWDGWHL
CCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCHH
LDAAERALGEPEGRERKKIVEWNDMVRHARPEYDI
HHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SRPLRVAVVGAGPAGIYASDLLMKSDTDVQIDLFERMPAPFGLIRYGVAPDHPRIKGIV
CCCEEEEEEECCCCCHHHHHHEEECCCCEEEEHHHHCCCCHHHEEECCCCCCHHHHHHH
KSLHNVMDKEQLRFLGNIEVGKDITVEELREFYDAIVFSTGATGDQDLRVPGSDLEGSWG
HHHHHHHCHHHHHHHCCCCCCCCCCHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCC
AGEFVGFYDGNPNFERNWDLSAEKVAVVGVGNVALDVARILAKTGDELLVTEIPDNVYES
CCCEEEEECCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCEEEECCCHHHHHH
LAKNQAKEVHVFGRRGPAQAKFTPLELKELDHSDTIEVIVNPEDIDYDAASEQARRDSKS
HHHCCCCEEEEECCCCCCCCCCCCHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHCCCH
QDLVCQTLESYAMRDPKGAPHKLFIHFFESPVEILGEDGKVVGLKTERTQLDGNGGVTGT
HHHHHHHHHHHHHCCCCCCCCEEEEEEHHCHHHHCCCCCCEEEEEECCEEECCCCCCCCC
GEFKTWDVQSVYRAVGYRSDAIEGVPFDDERAVVPNDGGHIIDPEVGSPITGLYATGWIK
CCCEECCHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCEEECCCCCCCCCCHHHHCCCC
RGPIGLIGNTKSDAKETTEMLLADHAAGSLPAPAKPELESIIEFLDERKVAFTTWDGWHL
CCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCHH
LDAAERALGEPEGRERKKIVEWNDMVRHARPEYDI
HHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036; 12071965; 12614197; 12102623 [H]