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The map label for this gene is ppa [H]

Identifier: 145296696

GI number: 145296696

Start: 2872979

End: 2873455

Strand: Direct

Name: ppa [H]

Synonym: cgR_2601

Alternate gene names: 145296696

Gene position: 2872979-2873455 (Clockwise)

Preceding gene: 145296679

Following gene: 145296697

Centisome position: 86.69

GC content: 55.97

Gene sequence:

>477_bases
ATGAGCATCGAAGTAACCGTCGAAATCCCTAAGGGATCACGCAACAAGTACGAAATCGACCACGAGACCGGAAAGGTCTA
CCTCGACCGCTACCTGTTCACTCCAATGGCATACCCACTGGACTACGGCTACATCGACCACACCCTCGGCGAAGACGGCG
ACCCATTGGATGCACTGGTCATCCTCCCCGAGTCCGTTTTCCCAGCAGTTGTGGTTAAGTCCCGCATCATCGGTGTCTTC
AAGATGACCGACGAAGCCGGCGGCGACGACAAGCTACTCTCCGTTCTCGACGACCCACGCTACGACCACATCCAGGACAT
CTCCGACGTGTCCGATTTCCTCAAGGATGAGATCGAGCACTTCTTCGTCCACTACAAGGACCTGGAAAAGGGCAAGCACG
TTGACGGTTCCGGCTGGGGCGACAAGGCTGAGGCTGAAAAGATCCACGCTGAGGCACTCGAGCGCTACAAAGCATAA

Upstream 100 bases:

>100_bases
TTCCAAAATTTTCGAGGATTTCCTTGCCCCGGGTCTCGTTTATTTTTGAACACGCTAGAATTCAAGGGCAGTAACTAATT
TCAACCCGGGAGAAATACCT

Downstream 100 bases:

>100_bases
GTCTTTTGTAATTTAAGAGCTGCGCACCCCGCCGATTCCGGTTTCCCCGGATTGTTTAGGTAAGGTGCGCAGCTTTTTGC
ATGCTTGCTTGGGCTGGGAG

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MSIEVTVEIPKGSRNKYEIDHETGKVYLDRYLFTPMAYPLDYGYIDHTLGEDGDPLDALVILPESVFPAVVVKSRIIGVF
KMTDEAGGDDKLLSVLDDPRYDHIQDISDVSDFLKDEIEHFFVHYKDLEKGKHVDGSGWGDKAEAEKIHAEALERYKA

Sequences:

>Translated_158_residues
MSIEVTVEIPKGSRNKYEIDHETGKVYLDRYLFTPMAYPLDYGYIDHTLGEDGDPLDALVILPESVFPAVVVKSRIIGVF
KMTDEAGGDDKLLSVLDDPRYDHIQDISDVSDFLKDEIEHFFVHYKDLEKGKHVDGSGWGDKAEAEKIHAEALERYKA
>Mature_157_residues
SIEVTVEIPKGSRNKYEIDHETGKVYLDRYLFTPMAYPLDYGYIDHTLGEDGDPLDALVILPESVFPAVVVKSRIIGVFK
MTDEAGGDDKLLSVLDDPRYDHIQDISDVSDFLKDEIEHFFVHYKDLEKGKHVDGSGWGDKAEAEKIHAEALERYKA

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=159, Percent_Identity=48.4276729559748, Blast_Score=148, Evalue=2e-37,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 17919; Mature: 17788

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIEVTVEIPKGSRNKYEIDHETGKVYLDRYLFTPMAYPLDYGYIDHTLGEDGDPLDALV
CCEEEEEECCCCCCCCEEEECCCCCEEEHHHHHCCCCCCCCCCCCHHCCCCCCCCCEEEE
ILPESVFPAVVVKSRIIGVFKMTDEAGGDDKLLSVLDDPRYDHIQDISDVSDFLKDEIEH
ECCCHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
FFVHYKDLEKGKHVDGSGWGDKAEAEKIHAEALERYKA
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SIEVTVEIPKGSRNKYEIDHETGKVYLDRYLFTPMAYPLDYGYIDHTLGEDGDPLDALV
CEEEEEECCCCCCCCEEEECCCCCEEEHHHHHCCCCCCCCCCCCHHCCCCCCCCCEEEE
ILPESVFPAVVVKSRIIGVFKMTDEAGGDDKLLSVLDDPRYDHIQDISDVSDFLKDEIEH
ECCCHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
FFVHYKDLEKGKHVDGSGWGDKAEAEKIHAEALERYKA
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12840036 [H]