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The map label for this gene is alsR [H]

Identifier: 145296616

GI number: 145296616

Start: 2790267

End: 2791154

Strand: Reverse

Name: alsR [H]

Synonym: cgR_2524

Alternate gene names: 145296616

Gene position: 2791154-2790267 (Counterclockwise)

Preceding gene: 145296617

Following gene: 145296615

Centisome position: 84.22

GC content: 54.28

Gene sequence:

>888_bases
GTGGAGATTCGTTGGTTGGAAGGCTTTATCGCGGTCGCGGAAGAATTGCACTTTAGTAATGCTGCGATTCGTTTGGGGAT
GCCGCAGTCGCCGTTGAGTCAGCTGATCCGGCGGTTGGAGTCGGAGTTGGGGCAGAAGCTTTTTGATCGCAGTACCCGGT
CAGTGGAGTTAACTGCCGCGGGTCGGGCGTTTTTGCCGCATGCCAGGGGGATTGTGGCGAGCGCTGCGGTGGCGAGGGAA
GCTGTGAATGCTGCCGAGGGGGAGATCGTTGGTGTTGTTCGCATTGGTTTTTCTGGTGTGCTGAACTATTCCACGCTGCC
GCTTTTGACCAGTGAGGTGCATAAACGGCTTCCTAATGTGGAGTTGGAGCTCGTTGGTCAGAAGTTGACGAGGGAAGCGG
TAAGTTTGCTGCGCTTGGGGGCGTTGGATATTACGTTGATGGGTTTGCCCATTGAGGATCCAGAGATTGAGACTCGGCTG
ATTAGTTTGGAAGAGTTTTGCGTGGTGTTGCCGAAGGATCATCGTCTTGCGGGGGAAGACGTGGTGGATTTGGTGGATCT
GGCTGAAGATGGGTTTGTGACGACGCCGGAGTTTGCGGGGTCTGTGTTTAGGAATTCCACCTTTCAGTTGTGTGCTGAGG
CTGGTTTTGTGCCGAGGATCAGCCAGCAAGTTAATGATCCTTACATGGCGCTGTTGTTGGTGGGGGCTGGGGTAGGGGTG
GCGATCACGACGCATGGAACTGGTTTGTTGGCGCCACCGAATACTGTGCATTTGCCTATTAAGCAGCATTCGGTGGAGCT
TCGGCATGGCATTGCGTGGATGAAGGGTTCAGGTCGGGTCGCTAGGGATGCGGTCATCGATATTGCGTTGGATATCTTTA
AGCCTTAA

Upstream 100 bases:

>100_bases
TCCCTAGGCCGATACCCATGTGGAAATCTCGACGTCTTAAATGGACGATGAGAGCTAAAACCACGAACAGCTGGGATTTT
CCACGATAGGATTGGGTCTC

Downstream 100 bases:

>100_bases
GTGCAAAAGAGGCCTAAAAATTAGGGGGAAATTAGGTCTCAAACAGAGATTTTTTCAATTAGTTTTGTGGTGTTTTCACA
CGGCTTCACACTCTCAATAG

Product: hypothetical protein

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MEIRWLEGFIAVAEELHFSNAAIRLGMPQSPLSQLIRRLESELGQKLFDRSTRSVELTAAGRAFLPHARGIVASAAVARE
AVNAAEGEIVGVVRIGFSGVLNYSTLPLLTSEVHKRLPNVELELVGQKLTREAVSLLRLGALDITLMGLPIEDPEIETRL
ISLEEFCVVLPKDHRLAGEDVVDLVDLAEDGFVTTPEFAGSVFRNSTFQLCAEAGFVPRISQQVNDPYMALLLVGAGVGV
AITTHGTGLLAPPNTVHLPIKQHSVELRHGIAWMKGSGRVARDAVIDIALDIFKP

Sequences:

>Translated_295_residues
MEIRWLEGFIAVAEELHFSNAAIRLGMPQSPLSQLIRRLESELGQKLFDRSTRSVELTAAGRAFLPHARGIVASAAVARE
AVNAAEGEIVGVVRIGFSGVLNYSTLPLLTSEVHKRLPNVELELVGQKLTREAVSLLRLGALDITLMGLPIEDPEIETRL
ISLEEFCVVLPKDHRLAGEDVVDLVDLAEDGFVTTPEFAGSVFRNSTFQLCAEAGFVPRISQQVNDPYMALLLVGAGVGV
AITTHGTGLLAPPNTVHLPIKQHSVELRHGIAWMKGSGRVARDAVIDIALDIFKP
>Mature_295_residues
MEIRWLEGFIAVAEELHFSNAAIRLGMPQSPLSQLIRRLESELGQKLFDRSTRSVELTAAGRAFLPHARGIVASAAVARE
AVNAAEGEIVGVVRIGFSGVLNYSTLPLLTSEVHKRLPNVELELVGQKLTREAVSLLRLGALDITLMGLPIEDPEIETRL
ISLEEFCVVLPKDHRLAGEDVVDLVDLAEDGFVTTPEFAGSVFRNSTFQLCAEAGFVPRISQQVNDPYMALLLVGAGVGV
AITTHGTGLLAPPNTVHLPIKQHSVELRHGIAWMKGSGRVARDAVIDIALDIFKP

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI2367136, Length=267, Percent_Identity=32.2097378277154, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI1787879, Length=246, Percent_Identity=36.1788617886179, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1788887, Length=289, Percent_Identity=33.2179930795848, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI157672245, Length=302, Percent_Identity=28.8079470198675, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790399, Length=284, Percent_Identity=27.8169014084507, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1788748, Length=240, Percent_Identity=26.25, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1787601, Length=146, Percent_Identity=30.8219178082192, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789639, Length=237, Percent_Identity=28.6919831223629, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI145693105, Length=240, Percent_Identity=24.1666666666667, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081904, Length=201, Percent_Identity=28.8557213930348, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790208, Length=150, Percent_Identity=30.6666666666667, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787589, Length=64, Percent_Identity=53.125, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31946; Mature: 31946

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIRWLEGFIAVAEELHFSNAAIRLGMPQSPLSQLIRRLESELGQKLFDRSTRSVELTAA
CCEEHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
GRAFLPHARGIVASAAVAREAVNAAEGEIVGVVRIGFSGVLNYSTLPLLTSEVHKRLPNV
CCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHCCCCHHHHHHHHHHHHCCCC
ELELVGQKLTREAVSLLRLGALDITLMGLPIEDPEIETRLISLEEFCVVLPKDHRLAGED
EEEHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHEEEHHHHEEECCCCCCCCCHH
VVDLVDLAEDGFVTTPEFAGSVFRNSTFQLCAEAGFVPRISQQVNDPYMALLLVGAGVGV
HHHHHHHCCCCCEECHHHHHHHHCCCHHHHHHHCCCCCHHHHHCCCHHHHHHHHHCCCCE
AITTHGTGLLAPPNTVHLPIKQHSVELRHGIAWMKGSGRVARDAVIDIALDIFKP
EEEECCCEEECCCCEEEEEHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEIRWLEGFIAVAEELHFSNAAIRLGMPQSPLSQLIRRLESELGQKLFDRSTRSVELTAA
CCEEHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
GRAFLPHARGIVASAAVAREAVNAAEGEIVGVVRIGFSGVLNYSTLPLLTSEVHKRLPNV
CCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHCCCCHHHHHHHHHHHHCCCC
ELELVGQKLTREAVSLLRLGALDITLMGLPIEDPEIETRLISLEEFCVVLPKDHRLAGED
EEEHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHEEEHHHHEEECCCCCCCCCHH
VVDLVDLAEDGFVTTPEFAGSVFRNSTFQLCAEAGFVPRISQQVNDPYMALLLVGAGVGV
HHHHHHHCCCCCEECHHHHHHHHCCCHHHHHHHCCCCCHHHHHCCCHHHHHHHHHCCCCE
AITTHGTGLLAPPNTVHLPIKQHSVELRHGIAWMKGSGRVARDAVIDIALDIFKP
EEEECCCEEECCCCEEEEEHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]