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The map label for this gene is bsaA [H]

Identifier: 145296586

GI number: 145296586

Start: 2752303

End: 2752782

Strand: Reverse

Name: bsaA [H]

Synonym: cgR_2494

Alternate gene names: 145296586

Gene position: 2752782-2752303 (Counterclockwise)

Preceding gene: 145296588

Following gene: 145296585

Centisome position: 83.06

GC content: 50.42

Gene sequence:

>480_bases
GTGACTTCTATTCATGACATCAGCGTAACCCTCAATGACGGCACAGAAACCACCATGGCGGATTGGGCGGGCCACCTTTT
GCTCATCGTGAACGTGGCATCCAAGTGCGGACTCACGCCACAGTATGAAGGGCTTCAAAAACTGTATGAGGAATACCAAG
ATCGAGGCTTCTTTGTCATTGGCGTGCCTTGTAATCAATTCAACGGCCAGGAACCTGGAACTGATGCTGAAGTGTGTGCT
TTCGCGCAAAATCAGTACGACGTCACCTTCCCGCTCTTGAGCAAAACCGAGGTGAATGGGGAGGGTACCCACCCCCTGTA
CAAGGTGCTCAAAGAGGCAACTGGTGGTAGTGAAATCGAGTGGAATTTTGAGAAATTCCTGGTAGATGCAGAAGGTAACA
CGATTAAGCGCTTTGCTCCTCGGACGGAACCATCTGCAGCTGAGGTAGTGGAAGCAATCGAGGAGAATCTCCCTATCTAA

Upstream 100 bases:

>100_bases
CGACCTGGCAGTTCACCTTTGGTCTCACCAAAGTTCACCTATTAGCTGACTTTTATTTAGATGATGCACTAAATCCTCCC
CCTCAACTAGGGTTGCGATT

Downstream 100 bases:

>100_bases
GGGCTGGCTAGGTTTGACCAGTGGCAACAGTTACACTTGTGCTCGTAAAACATTGTCCTCCCCATTTCTTGAGTAAGGGA
AAATACCGTGGCCCGTGTAG

Product: hypothetical protein

Products: glutathione disulfide; H2O

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MTSIHDISVTLNDGTETTMADWAGHLLLIVNVASKCGLTPQYEGLQKLYEEYQDRGFFVIGVPCNQFNGQEPGTDAEVCA
FAQNQYDVTFPLLSKTEVNGEGTHPLYKVLKEATGGSEIEWNFEKFLVDAEGNTIKRFAPRTEPSAAEVVEAIEENLPI

Sequences:

>Translated_159_residues
MTSIHDISVTLNDGTETTMADWAGHLLLIVNVASKCGLTPQYEGLQKLYEEYQDRGFFVIGVPCNQFNGQEPGTDAEVCA
FAQNQYDVTFPLLSKTEVNGEGTHPLYKVLKEATGGSEIEWNFEKFLVDAEGNTIKRFAPRTEPSAAEVVEAIEENLPI
>Mature_158_residues
TSIHDISVTLNDGTETTMADWAGHLLLIVNVASKCGLTPQYEGLQKLYEEYQDRGFFVIGVPCNQFNGQEPGTDAEVCAF
AQNQYDVTFPLLSKTEVNGEGTHPLYKVLKEATGGSEIEWNFEKFLVDAEGNTIKRFAPRTEPSAAEVVEAIEENLPI

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=162, Percent_Identity=37.6543209876543, Blast_Score=110, Evalue=5e-25,
Organism=Homo sapiens, GI90903240, Length=162, Percent_Identity=37.6543209876543, Blast_Score=110, Evalue=7e-25,
Organism=Homo sapiens, GI15618997, Length=138, Percent_Identity=39.1304347826087, Blast_Score=108, Evalue=2e-24,
Organism=Homo sapiens, GI192455698, Length=141, Percent_Identity=36.1702127659575, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI4557629, Length=170, Percent_Identity=32.3529411764706, Blast_Score=90, Evalue=1e-18,
Organism=Homo sapiens, GI90903238, Length=130, Percent_Identity=37.6923076923077, Blast_Score=89, Evalue=1e-18,
Organism=Homo sapiens, GI6006001, Length=171, Percent_Identity=35.672514619883, Blast_Score=85, Evalue=3e-17,
Organism=Homo sapiens, GI41406084, Length=159, Percent_Identity=32.0754716981132, Blast_Score=80, Evalue=7e-16,
Organism=Homo sapiens, GI33186887, Length=148, Percent_Identity=35.1351351351351, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI32967607, Length=171, Percent_Identity=31.5789473684211, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788003, Length=179, Percent_Identity=45.2513966480447, Blast_Score=150, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17535473, Length=149, Percent_Identity=44.2953020134228, Blast_Score=135, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI17506887, Length=163, Percent_Identity=41.7177914110429, Blast_Score=134, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI193210707, Length=164, Percent_Identity=38.4146341463415, Blast_Score=112, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI71993584, Length=136, Percent_Identity=40.4411764705882, Blast_Score=111, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI193209493, Length=183, Percent_Identity=33.879781420765, Blast_Score=97, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17550320, Length=184, Percent_Identity=32.6086956521739, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319721, Length=151, Percent_Identity=45.6953642384106, Blast_Score=152, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6322228, Length=161, Percent_Identity=45.9627329192547, Blast_Score=149, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6322826, Length=161, Percent_Identity=40.9937888198758, Blast_Score=130, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24656772, Length=161, Percent_Identity=41.6149068322981, Blast_Score=123, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24656767, Length=161, Percent_Identity=41.6149068322981, Blast_Score=123, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24656777, Length=161, Percent_Identity=41.6149068322981, Blast_Score=122, Evalue=8e-29,
Organism=Drosophila melanogaster, GI85726443, Length=146, Percent_Identity=44.5205479452055, Blast_Score=120, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: 1.11.1.9

Molecular weight: Translated: 17561; Mature: 17430

Theoretical pI: Translated: 4.10; Mature: 4.10

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSIHDISVTLNDGTETTMADWAGHLLLIVNVASKCGLTPQYEGLQKLYEEYQDRGFFVI
CCCEEEEEEEECCCCCCHHHHHHCCEEEEEEEHHHCCCCCCHHHHHHHHHHHHHCCEEEE
GVPCNQFNGQEPGTDAEVCAFAQNQYDVTFPLLSKTEVNGEGTHPLYKVLKEATGGSEIE
EECCCCCCCCCCCCCHHHEEEECCCCEEEEECCCCEECCCCCCCHHHHHHHHCCCCCEEE
WNFEKFLVDAEGNTIKRFAPRTEPSAAEVVEAIEENLPI
EEHHHEEEECCCCEEEECCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
TSIHDISVTLNDGTETTMADWAGHLLLIVNVASKCGLTPQYEGLQKLYEEYQDRGFFVI
CCEEEEEEEECCCCCCHHHHHHCCEEEEEEEHHHCCCCCCHHHHHHHHHHHHHCCEEEE
GVPCNQFNGQEPGTDAEVCAFAQNQYDVTFPLLSKTEVNGEGTHPLYKVLKEATGGSEIE
EECCCCCCCCCCCCCHHHEEEECCCCEEEEECCCCEECCCCCCCHHHHHHHHCCCCCEEE
WNFEKFLVDAEGNTIKRFAPRTEPSAAEVVEAIEENLPI
EEHHHEEEECCCCEEEECCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutathione; H2O2

Specific reaction: 2 glutathione + H2O2 = glutathione disulfide + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10086841; 11058132 [H]