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The map label for this gene is dgoR [H]

Identifier: 145296524

GI number: 145296524

Start: 2676638

End: 2677390

Strand: Direct

Name: dgoR [H]

Synonym: cgR_2434

Alternate gene names: 145296524

Gene position: 2676638-2677390 (Clockwise)

Preceding gene: 145296523

Following gene: 145296527

Centisome position: 80.76

GC content: 56.97

Gene sequence:

>753_bases
ATGCCCCCAACAAACGAAAGTCCTATGACTAATCCATTAGGTTCTGCCCCCACCCCAGCCAAGCCACTTCTTGACAGTGT
TCTTGATGAGCTCGGTCAAGATATCGTCAGTGGCAAGGTTGCTGTCGGAGATACCTTCAAGCTGATGGACATCGGCGAAC
GTTTTGGTATTTCCCGCACAGTGGCACGCGAAGCGATGCGCGCTTTGGAGCAGCTCGGTCTTGTCGCGTCCTCACGTCGC
ATTGGCATTACTGTTTTGCCACAGGAAGAGTGGGCTGTTTTTGATAAGTCCATCATTCGCTGGCGTCTCAATGACGAAGG
TCAGCGTGAAGGACAACTGCAGTCGCTTACTGAGCTTCGTATCGCCATTGAGCCGATTGCCGCGCGCAGCGTTGCTCTTC
ACGCGTCAACCGCCGAGCTCGAGAAAATCCGCGCGCTGGCAACAGAGATGCGTCAGTTGGGTGAATCTGGTCAGGGTGCG
TCCCAGCGCTTCCTCGAAGCGGACGTCACCTTCCACGAGCTCATCTTGCGTTATTGCCACAATGAGATGTTCGCTGCACT
GATTCCGTCGATTAGCGCAGTTCTTGTCGGCCGCACCGAGCACGGCCTGCAGCCTGATCTGCCGGCGCACGAGGCGCTAG
ACAACCACGATAAGCTTGCCGACGCCCTCCTTAACCGCGACGCCGACGCCGCAGAAACCGCTTCCCGAAACATCCTCAAT
GAGGTGCGCAGCGCGCTGGGCACGCTGAACTAA

Upstream 100 bases:

>100_bases
CATTGGTATTTGCTCGAAAGCACAACTTAAAACAGTAATAATGGTAATCACATTCTTTTCTATTAAATAAGCAAGTACAC
CGGCCCATTAAAGAGGCACC

Downstream 100 bases:

>100_bases
CGTGATACGCGCACTGCGTTTGCCACCGCTAAGGGAATGTCTTGAAACATTTCCCCGATCTGCAGGCGCAGTGTGGCGAT
ATCGCTAAGAGCTTCAACGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MPPTNESPMTNPLGSAPTPAKPLLDSVLDELGQDIVSGKVAVGDTFKLMDIGERFGISRTVAREAMRALEQLGLVASSRR
IGITVLPQEEWAVFDKSIIRWRLNDEGQREGQLQSLTELRIAIEPIAARSVALHASTAELEKIRALATEMRQLGESGQGA
SQRFLEADVTFHELILRYCHNEMFAALIPSISAVLVGRTEHGLQPDLPAHEALDNHDKLADALLNRDADAAETASRNILN
EVRSALGTLN

Sequences:

>Translated_250_residues
MPPTNESPMTNPLGSAPTPAKPLLDSVLDELGQDIVSGKVAVGDTFKLMDIGERFGISRTVAREAMRALEQLGLVASSRR
IGITVLPQEEWAVFDKSIIRWRLNDEGQREGQLQSLTELRIAIEPIAARSVALHASTAELEKIRALATEMRQLGESGQGA
SQRFLEADVTFHELILRYCHNEMFAALIPSISAVLVGRTEHGLQPDLPAHEALDNHDKLADALLNRDADAAETASRNILN
EVRSALGTLN
>Mature_249_residues
PPTNESPMTNPLGSAPTPAKPLLDSVLDELGQDIVSGKVAVGDTFKLMDIGERFGISRTVAREAMRALEQLGLVASSRRI
GITVLPQEEWAVFDKSIIRWRLNDEGQREGQLQSLTELRIAIEPIAARSVALHASTAELEKIRALATEMRQLGESGQGAS
QRFLEADVTFHELILRYCHNEMFAALIPSISAVLVGRTEHGLQPDLPAHEALDNHDKLADALLNRDADAAETASRNILNE
VRSALGTLN

Specific function: Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994955, Length=216, Percent_Identity=31.0185185185185, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI48994961, Length=233, Percent_Identity=29.6137339055794, Blast_Score=91, Evalue=6e-20,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27259; Mature: 27128

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPTNESPMTNPLGSAPTPAKPLLDSVLDELGQDIVSGKVAVGDTFKLMDIGERFGISRT
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHCHHHH
VAREAMRALEQLGLVASSRRIGITVLPQEEWAVFDKSIIRWRLNDEGQREGQLQSLTELR
HHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHH
IAIEPIAARSVALHASTAELEKIRALATEMRQLGESGQGASQRFLEADVTFHELILRYCH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHH
NEMFAALIPSISAVLVGRTEHGLQPDLPAHEALDNHDKLADALLNRDADAAETASRNILN
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHH
EVRSALGTLN
HHHHHHCCCC
>Mature Secondary Structure 
PPTNESPMTNPLGSAPTPAKPLLDSVLDELGQDIVSGKVAVGDTFKLMDIGERFGISRT
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHCHHHH
VAREAMRALEQLGLVASSRRIGITVLPQEEWAVFDKSIIRWRLNDEGQREGQLQSLTELR
HHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHH
IAIEPIAARSVALHASTAELEKIRALATEMRQLGESGQGASQRFLEADVTFHELILRYCH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHH
NEMFAALIPSISAVLVGRTEHGLQPDLPAHEALDNHDKLADALLNRDADAAETASRNILN
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHH
EVRSALGTLN
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]