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The map label for this gene is ctaD [H]

Identifier: 145296520

GI number: 145296520

Start: 2672207

End: 2673961

Strand: Reverse

Name: ctaD [H]

Synonym: cgR_2431

Alternate gene names: 145296520

Gene position: 2673961-2672207 (Counterclockwise)

Preceding gene: 145296521

Following gene: 145296518

Centisome position: 80.68

GC content: 55.38

Gene sequence:

>1755_bases
ATGACCGCTGTGGCGCCTAGGGTCGACGGGCACGTCGCCCCTCAGAGGCCCGAGCCGACAGGCCATGCACGCAAGGGCAG
CAAAGCATGGTTAATGATGACCACCACCGACCACAAGCAGCTGGGCATTATGTACATCATTATGTCCTTCAGCTTCTTCT
TCCTCGGTGGCTTGATGGCCCTGCTTATCCGAGCGGAGCTTTTCACCCCTGGTCTGCAGTTCCTGTCTAATGAGCAGTTC
AACCAGCTGTTCACCATGCACGGAACTGTCATGCTGCTGCTGTACGGAACTCCAATTGTTTGGGGTTTTGCTAACTACGT
CCTGCCACTTCAGATCGGTGCGCCTGACGTAGCTTTCCCACGTTTGAATGCTTTCGGCTTCTGGATCACCACCGTCGGTG
GTGTCGCGATGCTGACTGGCTTCCTGACCCCGGGTGGTGCTGCCGACTTCGGTTGGACCATGTACTCCCCACTGTCTGAC
GCAATTCACTCCCCAGGCCTTGGCTCTGACATGTGGATCGTCGGTGTCGGTGCAACTGGTATTGGCTCCGTTGCTTCCGC
AATTAACATGCTCACCACCATCCTCTGCCTCCGCGCACCTGGTATGACCATGTTCCGTATGCCTATTTTCACCTGGAATA
TCTTCGTTGTATCCGTTCTTGCTCTGCTGATCTTCCCACTGCTGCTCGCTGCTGCACTGGGTGTTCTGTACGACCGCAAG
CTTGGTGGACACCTGTACGATCCAGCTAACGGCGGCTCCCTCCTGTGGCAGCACCTGTTCTGGTTCTTCGGACACCCTGA
GGTTTACGTTCTGGCACTGCCGTTCTTCGGCATTGTTTCTGAGATCATTCCTGTGTTCTCCCGTAAGCCAATGTTCGGTT
ACGTCGGCCTGATCTTCGCAACCTTGTCCATTGGTGCACTGTCCATGGCTGTGTGGGCTCACCACATGTTCGTTACTGGC
GCAGTTTTGCTTCCGTTCTTCTCCTTCATGACGTTCCTGATTTCGGTTCCTACCGGCGTTAAGTTCTTCAACTGGGTTGG
AACCATGTGGAAGGGTCACATCACTTGGGAAACCCCAATGATCTGGTCTGTTGGCTTCATGGCTACCTTCCTCTTCGGTG
GTCTGACCGGCATTATGCTGGCGTCCCCACCACTGGACTTCCACTTGGCTGACTCCTACTTCCTGATCGCGCACTTCCAC
TACACCCTCTTCGGTACCGTGGTGTTCGCATCGTGTGCAGGCGTTTACTTCTGGTTCCCGAAGATGACTGGCCGCATGAT
GGACGAGCGTCTTGGCAAGATCCACTTCTGGTTGACCTTCATCGGTTTCCACGGAACGTTCCTCATCCAGCACTGGGTGG
GCAACATGGGTATGCCACGTCGTTACGCTGACTACCTGGATTCTGATGGTTTCACCATCTACAACCAGATCTCCACCGTG
TTCTCCTTCCTGCTTGGCCTGTCTGTCATTCCATTCATCTGGAACGTCTTCAAGTCCTGGCGCTACGGTGAGCTCGTTAC
CGTTGATGATCCTTGGGGTTACGGCAACTCCCTGGAGTGGGCAACCTCCTGCCCTCCTCCTCGCCACAACTTCGCATCCT
TGCCTCGTATCCGCTCCGAGCGCCCTGCGTTCGAGCTGCACTACCCGCACATGATTGAACGCATGCGCGCAGAGGCACAC
ACTGGACATCACGATGATATTAATGCTCCAGAATTGGGTACCGCCCCAGCCCTTGCATCTGACTCCAGCCGCTAA

Upstream 100 bases:

>100_bases
TTGGGTTGGCATCGGATCCTGCCTGTGGCCTAAGATCAGGCAGTGTTGTTAAAGGACGATCGGTAATCCGAATGGATCGT
CCCGTAGTCAGGAGGAACCT

Downstream 100 bases:

>100_bases
AAGCGTCTGATTTAAGTCGGTACCTGACTAAATAAGCACCAGCCCCAGCAGAGACAATCTGCCGGGGCTGGTGCTTTTCA
TATTCCGACTTGGGGCACCC

Product: hypothetical protein

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 584; Mature: 583

Protein sequence:

>584_residues
MTAVAPRVDGHVAPQRPEPTGHARKGSKAWLMMTTTDHKQLGIMYIIMSFSFFFLGGLMALLIRAELFTPGLQFLSNEQF
NQLFTMHGTVMLLLYGTPIVWGFANYVLPLQIGAPDVAFPRLNAFGFWITTVGGVAMLTGFLTPGGAADFGWTMYSPLSD
AIHSPGLGSDMWIVGVGATGIGSVASAINMLTTILCLRAPGMTMFRMPIFTWNIFVVSVLALLIFPLLLAAALGVLYDRK
LGGHLYDPANGGSLLWQHLFWFFGHPEVYVLALPFFGIVSEIIPVFSRKPMFGYVGLIFATLSIGALSMAVWAHHMFVTG
AVLLPFFSFMTFLISVPTGVKFFNWVGTMWKGHITWETPMIWSVGFMATFLFGGLTGIMLASPPLDFHLADSYFLIAHFH
YTLFGTVVFASCAGVYFWFPKMTGRMMDERLGKIHFWLTFIGFHGTFLIQHWVGNMGMPRRYADYLDSDGFTIYNQISTV
FSFLLGLSVIPFIWNVFKSWRYGELVTVDDPWGYGNSLEWATSCPPPRHNFASLPRIRSERPAFELHYPHMIERMRAEAH
TGHHDDINAPELGTAPALASDSSR

Sequences:

>Translated_584_residues
MTAVAPRVDGHVAPQRPEPTGHARKGSKAWLMMTTTDHKQLGIMYIIMSFSFFFLGGLMALLIRAELFTPGLQFLSNEQF
NQLFTMHGTVMLLLYGTPIVWGFANYVLPLQIGAPDVAFPRLNAFGFWITTVGGVAMLTGFLTPGGAADFGWTMYSPLSD
AIHSPGLGSDMWIVGVGATGIGSVASAINMLTTILCLRAPGMTMFRMPIFTWNIFVVSVLALLIFPLLLAAALGVLYDRK
LGGHLYDPANGGSLLWQHLFWFFGHPEVYVLALPFFGIVSEIIPVFSRKPMFGYVGLIFATLSIGALSMAVWAHHMFVTG
AVLLPFFSFMTFLISVPTGVKFFNWVGTMWKGHITWETPMIWSVGFMATFLFGGLTGIMLASPPLDFHLADSYFLIAHFH
YTLFGTVVFASCAGVYFWFPKMTGRMMDERLGKIHFWLTFIGFHGTFLIQHWVGNMGMPRRYADYLDSDGFTIYNQISTV
FSFLLGLSVIPFIWNVFKSWRYGELVTVDDPWGYGNSLEWATSCPPPRHNFASLPRIRSERPAFELHYPHMIERMRAEAH
TGHHDDINAPELGTAPALASDSSR
>Mature_583_residues
TAVAPRVDGHVAPQRPEPTGHARKGSKAWLMMTTTDHKQLGIMYIIMSFSFFFLGGLMALLIRAELFTPGLQFLSNEQFN
QLFTMHGTVMLLLYGTPIVWGFANYVLPLQIGAPDVAFPRLNAFGFWITTVGGVAMLTGFLTPGGAADFGWTMYSPLSDA
IHSPGLGSDMWIVGVGATGIGSVASAINMLTTILCLRAPGMTMFRMPIFTWNIFVVSVLALLIFPLLLAAALGVLYDRKL
GGHLYDPANGGSLLWQHLFWFFGHPEVYVLALPFFGIVSEIIPVFSRKPMFGYVGLIFATLSIGALSMAVWAHHMFVTGA
VLLPFFSFMTFLISVPTGVKFFNWVGTMWKGHITWETPMIWSVGFMATFLFGGLTGIMLASPPLDFHLADSYFLIAHFHY
TLFGTVVFASCAGVYFWFPKMTGRMMDERLGKIHFWLTFIGFHGTFLIQHWVGNMGMPRRYADYLDSDGFTIYNQISTVF
SFLLGLSVIPFIWNVFKSWRYGELVTVDDPWGYGNSLEWATSCPPPRHNFASLPRIRSERPAFELHYPHMIERMRAEAHT
GHHDDINAPELGTAPALASDSSR

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=513, Percent_Identity=41.5204678362573, Blast_Score=363, Evalue=1e-100,
Organism=Escherichia coli, GI1786634, Length=552, Percent_Identity=42.7536231884058, Blast_Score=404, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6226519, Length=538, Percent_Identity=37.1747211895911, Blast_Score=345, Evalue=1e-95,
Organism=Saccharomyces cerevisiae, GI6226524, Length=318, Percent_Identity=40.251572327044, Blast_Score=234, Evalue=3e-62,
Organism=Saccharomyces cerevisiae, GI6226523, Length=244, Percent_Identity=38.1147540983607, Blast_Score=145, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 65117; Mature: 64986

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVAPRVDGHVAPQRPEPTGHARKGSKAWLMMTTTDHKQLGIMYIIMSFSFFFLGGLMA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
LLIRAELFTPGLQFLSNEQFNQLFTMHGTVMLLLYGTPIVWGFANYVLPLQIGAPDVAFP
HHHHHHHHCCHHHHHCCHHHHHHHHHHHHEEEEEECCCHHHHHHCCEEEEEECCCCCCCC
RLNAFGFWITTVGGVAMLTGFLTPGGAADFGWTMYSPLSDAIHSPGLGSDMWIVGVGATG
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCC
IGSVASAINMLTTILCLRAPGMTMFRMPIFTWNIFVVSVLALLIFPLLLAAALGVLYDRK
HHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LGGHLYDPANGGSLLWQHLFWFFGHPEVYVLALPFFGIVSEIIPVFSRKPMFGYVGLIFA
CCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHH
TLSIGALSMAVWAHHMFVTGAVLLPFFSFMTFLISVPTGVKFFNWVGTMWKGHITWETPM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEECCCH
IWSVGFMATFLFGGLTGIMLASPPLDFHLADSYFLIAHFHYTLFGTVVFASCAGVYFWFP
HHHHHHHHHHHHHHHHHHHEECCCCCEEECCCEEEEHHHHHHHHHHHHHHHHHHHHEEHH
KMTGRMMDERLGKIHFWLTFIGFHGTFLIQHWVGNMGMPRRYADYLDSDGFTIYNQISTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHH
FSFLLGLSVIPFIWNVFKSWRYGELVTVDDPWGYGNSLEWATSCPPPRHNFASLPRIRSE
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCC
RPAFELHYPHMIERMRAEAHTGHHDDINAPELGTAPALASDSSR
CCCEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TAVAPRVDGHVAPQRPEPTGHARKGSKAWLMMTTTDHKQLGIMYIIMSFSFFFLGGLMA
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
LLIRAELFTPGLQFLSNEQFNQLFTMHGTVMLLLYGTPIVWGFANYVLPLQIGAPDVAFP
HHHHHHHHCCHHHHHCCHHHHHHHHHHHHEEEEEECCCHHHHHHCCEEEEEECCCCCCCC
RLNAFGFWITTVGGVAMLTGFLTPGGAADFGWTMYSPLSDAIHSPGLGSDMWIVGVGATG
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCC
IGSVASAINMLTTILCLRAPGMTMFRMPIFTWNIFVVSVLALLIFPLLLAAALGVLYDRK
HHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LGGHLYDPANGGSLLWQHLFWFFGHPEVYVLALPFFGIVSEIIPVFSRKPMFGYVGLIFA
CCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHH
TLSIGALSMAVWAHHMFVTGAVLLPFFSFMTFLISVPTGVKFFNWVGTMWKGHITWETPM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEECCCH
IWSVGFMATFLFGGLTGIMLASPPLDFHLADSYFLIAHFHYTLFGTVVFASCAGVYFWFP
HHHHHHHHHHHHHHHHHHHEECCCCCEEECCCEEEEHHHHHHHHHHHHHHHHHHHHEEHH
KMTGRMMDERLGKIHFWLTFIGFHGTFLIQHWVGNMGMPRRYADYLDSDGFTIYNQISTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHH
FSFLLGLSVIPFIWNVFKSWRYGELVTVDDPWGYGNSLEWATSCPPPRHNFASLPRIRSE
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCC
RPAFELHYPHMIERMRAEAHTGHHDDINAPELGTAPALASDSSR
CCCEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11382224; 11577165; 12948626 [H]