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The map label for this gene is 145296509

Identifier: 145296509

GI number: 145296509

Start: 2661795

End: 2662544

Strand: Reverse

Name: 145296509

Synonym: cgR_2420

Alternate gene names: NA

Gene position: 2662544-2661795 (Counterclockwise)

Preceding gene: 145296511

Following gene: 145296508

Centisome position: 80.34

GC content: 51.87

Gene sequence:

>750_bases
ATGAGTTACAACAGCCCGTATAACAACACGAATTTCAGCACCACCGGCGCGTTCCAACCTGCTGGTGGGCCGGTGAAGCC
GTGGAATAAGCCTGATGGCAGCCTGAATCAGCAGCTGAAAAATAAATCCCGTGTGCGCACAGGTCTCACCATCGCCATCG
GTTATGTTGTGGTGATTTGGGCGGTGCATTTGGCATCAATCGTGATTGCGCTGCTCACTGGCTTCAACCTGACCAACTTT
GGTATTCATCCGCTGGATACCAGTGCACTGTGGGGTATTGTCACCTCACCGTTGCTGCATGGAAGCTTCAGTCACCTCAT
TGGAAATACCGTTCCAGGCTTTATATTCAGTTTCCTCATCGGTATGAGCGGCAAGCGCGTGTTCTGGGAAGTCACGATTA
TCGCAGGTCTCATCGGTGGTCTTGGTACATGGATTTTTGGTGGAATTGGTACCAACCACATCGGTGCGTCCGGCTTGATT
TACGGCTGGCTTGGCTACCTGATCGTGCGTGGAATTTTCAACAAAGATATTAAACAGTTCCTGCTTGGCGTGGTTTTAGC
GTTCATCTACTCCGGTTTGTTCTGGGGGTTGCTTCCTACCCAAATCGGTGTGTCCTGGCAGGGCCACCTTTTCGGTGCGC
TTGGTGGAATCGGTGCGGGTGCGTTTATCACGTCAGATGATCCCGCGGCACTGAAAGCGAAGAAGCGGCAGAAGCAACTG
GAAAAGCAACAACGCCAAAGAGGCTTGTAG

Upstream 100 bases:

>100_bases
TGTCAGCGCATGCTGCAGATTGTGTACAGGACGCTATTATCGACGCCATACTTACCGCGAGTCCGGGACTCGGGCTCAAA
AGCTTCAGGGAACTTTTACC

Downstream 100 bases:

>100_bases
TTTTCACCTAGCGACTACACTTAATTGACATGACAAGTGAGAATTCCGAATCCCAGGAGATTTGGCTTACCGATGAGCAG
CAAGATGTATGGCTCGATGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MSYNSPYNNTNFSTTGAFQPAGGPVKPWNKPDGSLNQQLKNKSRVRTGLTIAIGYVVVIWAVHLASIVIALLTGFNLTNF
GIHPLDTSALWGIVTSPLLHGSFSHLIGNTVPGFIFSFLIGMSGKRVFWEVTIIAGLIGGLGTWIFGGIGTNHIGASGLI
YGWLGYLIVRGIFNKDIKQFLLGVVLAFIYSGLFWGLLPTQIGVSWQGHLFGALGGIGAGAFITSDDPAALKAKKRQKQL
EKQQRQRGL

Sequences:

>Translated_249_residues
MSYNSPYNNTNFSTTGAFQPAGGPVKPWNKPDGSLNQQLKNKSRVRTGLTIAIGYVVVIWAVHLASIVIALLTGFNLTNF
GIHPLDTSALWGIVTSPLLHGSFSHLIGNTVPGFIFSFLIGMSGKRVFWEVTIIAGLIGGLGTWIFGGIGTNHIGASGLI
YGWLGYLIVRGIFNKDIKQFLLGVVLAFIYSGLFWGLLPTQIGVSWQGHLFGALGGIGAGAFITSDDPAALKAKKRQKQL
EKQQRQRGL
>Mature_248_residues
SYNSPYNNTNFSTTGAFQPAGGPVKPWNKPDGSLNQQLKNKSRVRTGLTIAIGYVVVIWAVHLASIVIALLTGFNLTNFG
IHPLDTSALWGIVTSPLLHGSFSHLIGNTVPGFIFSFLIGMSGKRVFWEVTIIAGLIGGLGTWIFGGIGTNHIGASGLIY
GWLGYLIVRGIFNKDIKQFLLGVVLAFIYSGLFWGLLPTQIGVSWQGHLFGALGGIGAGAFITSDDPAALKAKKRQKQLE
KQQRQRGL

Specific function: Unknown

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae ML1171 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022764 [H]

Pfam domain/function: PF01694 Rhomboid [H]

EC number: NA

Molecular weight: Translated: 26785; Mature: 26653

Theoretical pI: Translated: 10.79; Mature: 10.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCC
>Mature Secondary Structure 
SYNSPYNNTNFSTTGAFQPAGGPVKPWNKPDGSLNQQLKNKSRVRTGLTIAIGYVVVIW
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVHLASIVIALLTGFNLTNFGIHPLDTSALWGIVTSPLLHGSFSHLIGNTVPGFIFSFLI
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHH
GMSGKRVFWEVTIIAGLIGGLGTWIFGGIGTNHIGASGLIYGWLGYLIVRGIFNKDIKQF
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LLGVVLAFIYSGLFWGLLPTQIGVSWQGHLFGALGGIGAGAFITSDDPAALKAKKRQKQL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHH
EKQQRQRGL
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]