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The map label for this gene is xylB [H]

Identifier: 145296459

GI number: 145296459

Start: 2607067

End: 2608167

Strand: Direct

Name: xylB [H]

Synonym: cgR_2372

Alternate gene names: 145296459

Gene position: 2607067-2608167 (Clockwise)

Preceding gene: 145296458

Following gene: 145296461

Centisome position: 78.66

GC content: 56.13

Gene sequence:

>1101_bases
ATGCAAACCCTTGCTGCTATTGTTCGTGCCACGAAGCAACCTTTTGAGATCGCCACCATTGATCTGGATGAGCCACGACC
AGATGAAGTTCAAGTTCGAGTTATTGCTGCCGGAGTGTGCCACACCGACGCAATTGTTCGTGATCAGATTTACCCAACGT
TCCTTCCCGCAGTTTTCGGCCACGAAGGTGCCGGAGTAGTTGTCGCCGTGGGTTCTGCCGTTACCTCGGTGAAACCAGAT
GACAAGGTAGTGCTGGGATTCAACTCTTGTGGTCAGTGCTTGAAGTGTTTGGGTGGTAAACCTGCGTACTGTGAGAAATT
CTATGATCGCAACTTCGCATGTACCCGCGATGACGGTTCGACTGCCTTCTCTGAAGACGGCGAGCAAGTAGGTTCTCATT
TCTTCGGCCAATCCACATTTGCCAACTACACCAATGTGTCAGCACGCAGCGTGGTCAAGGTCGATGACGATGTTCCTTTG
GAGCTCCTTGGACCTCTCGGCTGCGGTCTGTCCACTGGTGCTGGCGCGATTCTCAACTCGCTTGGCGTTCGCGCCGGCGA
TACCGTCGCGGTCTTTGGCACTGGAGCTGTCGGTTCCGCAGCGATCATGGCGGCAGCGGCAACCGGAGCGACCACCATCA
TTGCCGTTGATATCCACAATTCCCGCCTTGAGATGGCAAAAGAGCTCGGAGCCACCCACACGATCAACTCCAAGGATGAG
GATCCCGCGGAGAAGATCAAGCAATTGACCGGCGATGGCGTGCAGTTCGCCCTCGATACAACTGGTGTCGTGGCTGTGAC
TAGGCAGGCTGCTGATTCCTTGGCCATCAACGGTACTGTCGGTCTTGTCGGCGCCCCGGCACCTGGTGCGGAGGCTACCT
TTGAGGTCGGCGCGTCCCTGGTTCGGGGTTGGAAGTTCCAGACGATCATCGAGGGCGACGCCGTCCCTCAGGATTTCATC
CCTCGCCTGGTTCATTTGTGGCGCCAGGGCAAGTTCCCGATCGAGAAGCTCGTGCGCACTTACCCGCTGGAACACATCAA
TGATGCCTTTGCGGATTCCGCCAGTGGCGAGGTCATTAAGCCGATTATCACGTTCCCTTAA

Upstream 100 bases:

>100_bases
GGCCTTGGCAGAGAACTCGGCCCCGAAGGTCTTGCTTCCTACCAAGAAACCCAAACCATTTATCTCTAATCCAAACTGCA
CCTATATATAAGGAGTAAAA

Downstream 100 bases:

>100_bases
AAGCAAAAGATTTTTGCTTATCGACGCCTACCTCCAGCTCAACTAGGCAGACGAAGAAAAGCCACCTCCTTGAGATCAAG
GAGGTGGCTTATCTTTTAGC

Product: hypothetical protein

Products: NA

Alternate protein names: Benzyl alcohol dehydrogenase; BADH [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MQTLAAIVRATKQPFEIATIDLDEPRPDEVQVRVIAAGVCHTDAIVRDQIYPTFLPAVFGHEGAGVVVAVGSAVTSVKPD
DKVVLGFNSCGQCLKCLGGKPAYCEKFYDRNFACTRDDGSTAFSEDGEQVGSHFFGQSTFANYTNVSARSVVKVDDDVPL
ELLGPLGCGLSTGAGAILNSLGVRAGDTVAVFGTGAVGSAAIMAAAATGATTIIAVDIHNSRLEMAKELGATHTINSKDE
DPAEKIKQLTGDGVQFALDTTGVVAVTRQAADSLAINGTVGLVGAPAPGAEATFEVGASLVRGWKFQTIIEGDAVPQDFI
PRLVHLWRQGKFPIEKLVRTYPLEHINDAFADSASGEVIKPIITFP

Sequences:

>Translated_366_residues
MQTLAAIVRATKQPFEIATIDLDEPRPDEVQVRVIAAGVCHTDAIVRDQIYPTFLPAVFGHEGAGVVVAVGSAVTSVKPD
DKVVLGFNSCGQCLKCLGGKPAYCEKFYDRNFACTRDDGSTAFSEDGEQVGSHFFGQSTFANYTNVSARSVVKVDDDVPL
ELLGPLGCGLSTGAGAILNSLGVRAGDTVAVFGTGAVGSAAIMAAAATGATTIIAVDIHNSRLEMAKELGATHTINSKDE
DPAEKIKQLTGDGVQFALDTTGVVAVTRQAADSLAINGTVGLVGAPAPGAEATFEVGASLVRGWKFQTIIEGDAVPQDFI
PRLVHLWRQGKFPIEKLVRTYPLEHINDAFADSASGEVIKPIITFP
>Mature_366_residues
MQTLAAIVRATKQPFEIATIDLDEPRPDEVQVRVIAAGVCHTDAIVRDQIYPTFLPAVFGHEGAGVVVAVGSAVTSVKPD
DKVVLGFNSCGQCLKCLGGKPAYCEKFYDRNFACTRDDGSTAFSEDGEQVGSHFFGQSTFANYTNVSARSVVKVDDDVPL
ELLGPLGCGLSTGAGAILNSLGVRAGDTVAVFGTGAVGSAAIMAAAATGATTIIAVDIHNSRLEMAKELGATHTINSKDE
DPAEKIKQLTGDGVQFALDTTGVVAVTRQAADSLAINGTVGLVGAPAPGAEATFEVGASLVRGWKFQTIIEGDAVPQDFI
PRLVHLWRQGKFPIEKLVRTYPLEHINDAFADSASGEVIKPIITFP

Specific function: Oxidizes primary alcohols with an aromatic or cyclohex- 1-ene ring. It is highly specific for benzyl alcohol [H]

COG id: COG1062

COG function: function code C; Zn-dependent alcohol dehydrogenases, class III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI34577061, Length=372, Percent_Identity=37.0967741935484, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI4501929, Length=372, Percent_Identity=36.8279569892473, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI4501933, Length=372, Percent_Identity=36.2903225806452, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI71565152, Length=375, Percent_Identity=36.2666666666667, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI262073058, Length=370, Percent_Identity=33.2432432432432, Blast_Score=195, Evalue=6e-50,
Organism=Homo sapiens, GI71743840, Length=370, Percent_Identity=33.2432432432432, Blast_Score=195, Evalue=7e-50,
Organism=Homo sapiens, GI71565154, Length=368, Percent_Identity=33.9673913043478, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI156523966, Length=370, Percent_Identity=33.2432432432432, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI4501939, Length=362, Percent_Identity=33.4254143646409, Blast_Score=183, Evalue=3e-46,
Organism=Escherichia coli, GI1786552, Length=371, Percent_Identity=35.5795148247978, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI87082125, Length=382, Percent_Identity=28.0104712041885, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788073, Length=364, Percent_Identity=27.7472527472527, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1788407, Length=266, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87081918, Length=371, Percent_Identity=27.2237196765499, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1786518, Length=295, Percent_Identity=31.864406779661, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790045, Length=279, Percent_Identity=25.089605734767, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787863, Length=366, Percent_Identity=24.5901639344262, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI226510992, Length=383, Percent_Identity=25.3263707571802, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25146526, Length=375, Percent_Identity=36.5333333333333, Blast_Score=203, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI71997431, Length=377, Percent_Identity=36.3395225464191, Blast_Score=198, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17565904, Length=346, Percent_Identity=36.4161849710983, Blast_Score=176, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17562876, Length=369, Percent_Identity=26.2872628726287, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17562584, Length=281, Percent_Identity=25.6227758007117, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17562878, Length=356, Percent_Identity=25.561797752809, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71988145, Length=217, Percent_Identity=30.4147465437788, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17562582, Length=288, Percent_Identity=26.0416666666667, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6320033, Length=373, Percent_Identity=34.0482573726542, Blast_Score=199, Evalue=7e-52,
Organism=Saccharomyces cerevisiae, GI6323729, Length=300, Percent_Identity=29.6666666666667, Blast_Score=92, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6323961, Length=302, Percent_Identity=30.1324503311258, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319621, Length=287, Percent_Identity=30.3135888501742, Blast_Score=90, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6324486, Length=300, Percent_Identity=28.6666666666667, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6319258, Length=290, Percent_Identity=29.3103448275862, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323980, Length=265, Percent_Identity=27.1698113207547, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17737895, Length=370, Percent_Identity=35.1351351351351, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI17137530, Length=265, Percent_Identity=30.188679245283, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17737897, Length=354, Percent_Identity=27.9661016949153, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.90 [H]

Molecular weight: Translated: 38333; Mature: 38333

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTLAAIVRATKQPFEIATIDLDEPRPDEVQVRVIAAGVCHTDAIVRDQIYPTFLPAVFG
CHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEEEECCHHHHHHHHHCCCHHHHHHHHC
HEGAGVVVAVGSAVTSVKPDDKVVLGFNSCGQCLKCLGGKPAYCEKFYDRNFACTRDDGS
CCCCEEEEEECCHHCCCCCCCCEEEECHHHHHHHHHHCCCCHHHHHHHCCCCEEECCCCC
TAFSEDGEQVGSHFFGQSTFANYTNVSARSVVKVDDDVPLELLGPLGCGLSTGAGAILNS
CCHHCCHHHHHHHHCCCCHHCCCCCCCCCEEEEECCCCCHHHHCCCCCCCCCCHHHHHHH
LGVRAGDTVAVFGTGAVGSAAIMAAAATGATTIIAVDIHNSRLEMAKELGATHTINSKDE
CCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEEEEEECCHHHHHHHHCCCCCCCCCCCC
DPAEKIKQLTGDGVQFALDTTGVVAVTRQAADSLAINGTVGLVGAPAPGAEATFEVGASL
CHHHHHHHHCCCCEEEEEECCCEEEEEHHHHCCEEECCEEEEEECCCCCCCHHHHHHHHH
VRGWKFQTIIEGDAVPQDFIPRLVHLWRQGKFPIEKLVRTYPLEHINDAFADSASGEVIK
HCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHCCCCCCCEEC
PIITFP
CEECCC
>Mature Secondary Structure
MQTLAAIVRATKQPFEIATIDLDEPRPDEVQVRVIAAGVCHTDAIVRDQIYPTFLPAVFG
CHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEEEECCHHHHHHHHHCCCHHHHHHHHC
HEGAGVVVAVGSAVTSVKPDDKVVLGFNSCGQCLKCLGGKPAYCEKFYDRNFACTRDDGS
CCCCEEEEEECCHHCCCCCCCCEEEECHHHHHHHHHHCCCCHHHHHHHCCCCEEECCCCC
TAFSEDGEQVGSHFFGQSTFANYTNVSARSVVKVDDDVPLELLGPLGCGLSTGAGAILNS
CCHHCCHHHHHHHHCCCCHHCCCCCCCCCEEEEECCCCCHHHHCCCCCCCCCCHHHHHHH
LGVRAGDTVAVFGTGAVGSAAIMAAAATGATTIIAVDIHNSRLEMAKELGATHTINSKDE
CCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEEEEEECCHHHHHHHHCCCCCCCCCCCC
DPAEKIKQLTGDGVQFALDTTGVVAVTRQAADSLAINGTVGLVGAPAPGAEATFEVGASL
CHHHHHHHHCCCCEEEEEECCCEEEEEHHHHCCEEECCEEEEEECCCCCCCHHHHHHHHH
VRGWKFQTIIEGDAVPQDFIPRLVHLWRQGKFPIEKLVRTYPLEHINDAFADSASGEVIK
HCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHCCCCCCCEEC
PIITFP
CEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8496150; 1989592 [H]