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The map label for this gene is xylB [H]

Identifier: 145296415

GI number: 145296415

Start: 2562499

End: 2563623

Strand: Direct

Name: xylB [H]

Synonym: cgR_2329

Alternate gene names: 145296415

Gene position: 2562499-2563623 (Clockwise)

Preceding gene: 145296414

Following gene: 145296416

Centisome position: 77.32

GC content: 60.44

Gene sequence:

>1125_bases
ATGAAGATTGATGCTTATGTGGTAGAGGAGATCAACGCACCTCTGGTCCGCGAAACACTCACCATTGACGACCCCGGCCC
GGGTGAAGTCTTGGTCAAGGTGGTGGCCACCGGTGTGTGCCACACTGATCTGAACACCCAATCCGGTGACATGCCCCTGC
CACTGCCCGGTGTCCTAGGTCATGAGGGCTCCGGTGTCGTCGAAGCCGTCGGCGCGGGTGTGACCGAGGTCGAGCCCGGT
GACCACGTCATCATGGGCTGGCCCTACTGCGGCACCTGCCGCAACTGTGTCCGCGGTGAGCACCGCTACTGCCTCAACAT
CGGAGCCGAACTGCTTGCGGGAGTACGTCTGCACGGACCTGATGCTGGGTCCTCTGCCTATACCCGGGCCGATGGCACCG
CGCTGTCGGGGCATTTCTTCGGTCAGTCCTCCTTTGCCACTTATTCTCTGACCCGCGCGAATGCGGTAGTGAAAGTGGAT
AAGGATATCGACCTCGCACTGTTGGGTCCCCTGGCCTGTGGCATCACTACCGGAGCGGGCGCGGTGTTTAATACCGCCCA
GCCCGGTCCGGGCGAATCAATTGTCATCATCGGTGCCGGTGCCGTCGGCCTGGCTGCGGTTATGGCTGCCCGCAATACCC
CGGCGGCCACCATTATTGCGATGGACCTGCAGGACTCACGTCTGGAGTTGGCTCGTGAACTTGGTGCCACCCATACCGTT
AATACCCGTGAGAAGGACATCGTCGAGGCCGTCACCGAGATCTGCGGTGGCCCAGCCGACTACGTCCTGGACTGCACCGG
CAGCATCAAGGTCATCGAGCAAGCCGCGGACGCCGTCGGACTGATGGGTACGTTCATCCTTGTCGGTGGAGCCCCGGCTG
AGGCACGTTTTTCCCTTGACCACATGCGCACGCTATTCGGCAAGACCGTGGTTGGGACCCTGGGCGGTTCCTCAAACAGT
CGCACCCTGATCCCCGGTCTGATCAACCTCTACCGACAGGGAAGATTCCCCTTTGACAAGCTGATCACCACCTATGGCTT
CGACGAGCTCGATCAAGCCATCCACGATGCTCATGAAGGCGGCACTATCAAAGCCGTGCTCCGAGTTGATAAAACCAACC
AGTAA

Upstream 100 bases:

>100_bases
ATGGAACATTCGACGCGGAAGGTTATGAGTTCCGCGATGTCCCCGCCACTGCCCCAGCAACCCTTTAAGGCTTTACCCCT
AATACTTAAGGAGATAGAAC

Downstream 100 bases:

>100_bases
CCCACAACCACTGAACCGACTACGCATCAACGAAAGCAGCTAAGAACAATGACCGTTACTACCCCTACTACATATTCCGC
CATCGTCGCCGACCAGCTCT

Product: hypothetical protein

Products: NA

Alternate protein names: Benzyl alcohol dehydrogenase; BADH [H]

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MKIDAYVVEEINAPLVRETLTIDDPGPGEVLVKVVATGVCHTDLNTQSGDMPLPLPGVLGHEGSGVVEAVGAGVTEVEPG
DHVIMGWPYCGTCRNCVRGEHRYCLNIGAELLAGVRLHGPDAGSSAYTRADGTALSGHFFGQSSFATYSLTRANAVVKVD
KDIDLALLGPLACGITTGAGAVFNTAQPGPGESIVIIGAGAVGLAAVMAARNTPAATIIAMDLQDSRLELARELGATHTV
NTREKDIVEAVTEICGGPADYVLDCTGSIKVIEQAADAVGLMGTFILVGGAPAEARFSLDHMRTLFGKTVVGTLGGSSNS
RTLIPGLINLYRQGRFPFDKLITTYGFDELDQAIHDAHEGGTIKAVLRVDKTNQ

Sequences:

>Translated_374_residues
MKIDAYVVEEINAPLVRETLTIDDPGPGEVLVKVVATGVCHTDLNTQSGDMPLPLPGVLGHEGSGVVEAVGAGVTEVEPG
DHVIMGWPYCGTCRNCVRGEHRYCLNIGAELLAGVRLHGPDAGSSAYTRADGTALSGHFFGQSSFATYSLTRANAVVKVD
KDIDLALLGPLACGITTGAGAVFNTAQPGPGESIVIIGAGAVGLAAVMAARNTPAATIIAMDLQDSRLELARELGATHTV
NTREKDIVEAVTEICGGPADYVLDCTGSIKVIEQAADAVGLMGTFILVGGAPAEARFSLDHMRTLFGKTVVGTLGGSSNS
RTLIPGLINLYRQGRFPFDKLITTYGFDELDQAIHDAHEGGTIKAVLRVDKTNQ
>Mature_374_residues
MKIDAYVVEEINAPLVRETLTIDDPGPGEVLVKVVATGVCHTDLNTQSGDMPLPLPGVLGHEGSGVVEAVGAGVTEVEPG
DHVIMGWPYCGTCRNCVRGEHRYCLNIGAELLAGVRLHGPDAGSSAYTRADGTALSGHFFGQSSFATYSLTRANAVVKVD
KDIDLALLGPLACGITTGAGAVFNTAQPGPGESIVIIGAGAVGLAAVMAARNTPAATIIAMDLQDSRLELARELGATHTV
NTREKDIVEAVTEICGGPADYVLDCTGSIKVIEQAADAVGLMGTFILVGGAPAEARFSLDHMRTLFGKTVVGTLGGSSNS
RTLIPGLINLYRQGRFPFDKLITTYGFDELDQAIHDAHEGGTIKAVLRVDKTNQ

Specific function: Oxidizes primary alcohols with an aromatic or cyclohex- 1-ene ring. It is highly specific for benzyl alcohol [H]

COG id: COG1062

COG function: function code C; Zn-dependent alcohol dehydrogenases, class III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI34577061, Length=379, Percent_Identity=35.0923482849604, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI4501929, Length=379, Percent_Identity=33.7730870712401, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI4501933, Length=379, Percent_Identity=33.7730870712401, Blast_Score=201, Evalue=7e-52,
Organism=Homo sapiens, GI71565154, Length=376, Percent_Identity=34.3085106382979, Blast_Score=195, Evalue=5e-50,
Organism=Homo sapiens, GI71565152, Length=373, Percent_Identity=31.6353887399464, Blast_Score=191, Evalue=7e-49,
Organism=Homo sapiens, GI156523966, Length=373, Percent_Identity=31.3672922252011, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI4501939, Length=366, Percent_Identity=31.4207650273224, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI71743840, Length=375, Percent_Identity=30.1333333333333, Blast_Score=175, Evalue=8e-44,
Organism=Homo sapiens, GI262073058, Length=375, Percent_Identity=30.1333333333333, Blast_Score=174, Evalue=1e-43,
Organism=Escherichia coli, GI1786552, Length=374, Percent_Identity=35.2941176470588, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI87081918, Length=298, Percent_Identity=33.8926174496644, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788073, Length=358, Percent_Identity=29.0502793296089, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1788075, Length=355, Percent_Identity=27.6056338028169, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787863, Length=340, Percent_Identity=27.0588235294118, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87082125, Length=318, Percent_Identity=25.1572327044025, Blast_Score=79, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI25146526, Length=386, Percent_Identity=34.7150259067358, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI71997431, Length=388, Percent_Identity=34.5360824742268, Blast_Score=191, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI17565904, Length=351, Percent_Identity=33.3333333333333, Blast_Score=165, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17562582, Length=323, Percent_Identity=27.8637770897833, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17562584, Length=319, Percent_Identity=26.9592476489028, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71988145, Length=316, Percent_Identity=26.5822784810127, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320033, Length=380, Percent_Identity=36.0526315789474, Blast_Score=209, Evalue=8e-55,
Organism=Saccharomyces cerevisiae, GI6323961, Length=378, Percent_Identity=29.6296296296296, Blast_Score=104, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6324486, Length=324, Percent_Identity=30.8641975308642, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6323729, Length=295, Percent_Identity=30.5084745762712, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6319621, Length=327, Percent_Identity=29.9694189602446, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6322619, Length=370, Percent_Identity=28.1081081081081, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6319955, Length=374, Percent_Identity=27.807486631016, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17737895, Length=372, Percent_Identity=33.0645161290323, Blast_Score=184, Evalue=9e-47,
Organism=Drosophila melanogaster, GI17137530, Length=264, Percent_Identity=29.1666666666667, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17737897, Length=264, Percent_Identity=28.4090909090909, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.90 [H]

Molecular weight: Translated: 38936; Mature: 38936

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIDAYVVEEINAPLVRETLTIDDPGPGEVLVKVVATGVCHTDLNTQSGDMPLPLPGVLG
CCCCHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCC
HEGSGVVEAVGAGVTEVEPGDHVIMGWPYCGTCRNCVRGEHRYCLNIGAELLAGVRLHGP
CCCCCHHHHHCCCCEECCCCCEEEECCCCHHHHHHHHCCCCCEEEHHHHHHHCCCEEECC
DAGSSAYTRADGTALSGHFFGQSSFATYSLTRANAVVKVDKDIDLALLGPLACGITTGAG
CCCCCCEECCCCCEEECEECCCCCCEEEEEEECCEEEEECCCCCEEEECHHHHCCCCCCC
AVFNTAQPGPGESIVIIGAGAVGLAAVMAARNTPAATIIAMDLQDSRLELARELGATHTV
CEEECCCCCCCCEEEEEECCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCCC
NTREKDIVEAVTEICGGPADYVLDCTGSIKVIEQAADAVGLMGTFILVGGAPAEARFSLD
CCCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHH
HMRTLFGKTVVGTLGGSSNSRTLIPGLINLYRQGRFPFDKLITTYGFDELDQAIHDAHEG
HHHHHHHHHHEEECCCCCCCCEECHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHCCC
GTIKAVLRVDKTNQ
CEEEEEEEECCCCC
>Mature Secondary Structure
MKIDAYVVEEINAPLVRETLTIDDPGPGEVLVKVVATGVCHTDLNTQSGDMPLPLPGVLG
CCCCHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCC
HEGSGVVEAVGAGVTEVEPGDHVIMGWPYCGTCRNCVRGEHRYCLNIGAELLAGVRLHGP
CCCCCHHHHHCCCCEECCCCCEEEECCCCHHHHHHHHCCCCCEEEHHHHHHHCCCEEECC
DAGSSAYTRADGTALSGHFFGQSSFATYSLTRANAVVKVDKDIDLALLGPLACGITTGAG
CCCCCCEECCCCCEEECEECCCCCCEEEEEEECCEEEEECCCCCEEEECHHHHCCCCCCC
AVFNTAQPGPGESIVIIGAGAVGLAAVMAARNTPAATIIAMDLQDSRLELARELGATHTV
CEEECCCCCCCCEEEEEECCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCCC
NTREKDIVEAVTEICGGPADYVLDCTGSIKVIEQAADAVGLMGTFILVGGAPAEARFSLD
CCCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHH
HMRTLFGKTVVGTLGGSSNSRTLIPGLINLYRQGRFPFDKLITTYGFDELDQAIHDAHEG
HHHHHHHHHHEEECCCCCCCCEECHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHCCC
GTIKAVLRVDKTNQ
CEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8496150; 1989592 [H]