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The map label for this gene is pcaB [H]

Identifier: 145296363

GI number: 145296363

Start: 2508860

End: 2509963

Strand: Reverse

Name: pcaB [H]

Synonym: cgR_2278

Alternate gene names: 145296363

Gene position: 2509963-2508860 (Counterclockwise)

Preceding gene: 145296364

Following gene: 145296362

Centisome position: 75.73

GC content: 60.33

Gene sequence:

>1104_bases
TTGGACTCTAAATTGACCCGATCTTTATACTCCGACCTTGCTGGTAGTGGAGAACACCTCAGCAGCCTTTCCGACGAGAC
TTTCCTAAAGAATCTTCTTGTCGTGGAGGCCGCTTTGGCGGTTGCAGCTGCCCCCGAGCATGCAGCAATGGCGAAGGCCA
CCATTGATTCTTATCAGTTGGATGTGGAGGAGCTTTCCCGGCGCGCAGCCGAGGGCGGTAATCCGCTCATTCCGCTGGTC
ACTGACCTCAAGGCCATCAATCCGGCAGGCATCCACATTGGCGCAACGAGCCAGGACATCATTGATTCTGCGTTAATGCT
GTGCATGAAGGAAGGGGTGGGGGAGGTCGTCGACAAGCTTAAAAAGCTTGCGCGAGATTTGGCCGAGCTCACCGCGGAGC
ATAAAGCAACCCCGATCATGGGGCGCACGTTGGGGCAGATCGCGACGCCGACGACGTTCGGCGCGCTGACCGGCGGCTGG
CTGGTTGCGGTGGATAATGCGACGCGCGCGCTGGAGGCGCTGGAGTTTCCGGTGTCGTATGGCGGTGCCAGCGGAAATAT
GACGGCGGTGCACCCGCGCGGCTTCGAGATTCAGGCGAAGCTGGCCGAGGAGTTGGGCCTTTTTGATCCGCAGTGGGTGT
GGCATTCCGATCGCACGCCGATCACTGCGATCGCGTCGGCGCTGGCAACGGCCGCTGGTGTGGTACGTAAAATTGCTGGT
GACGTGGTGTTTTACTCACAAACCGAGGTCGGCGAGCTGCGTGAGAAATCCCCCGGCGGTAGCTCGGCAATGCCACACAA
AGCCAATCCGGCCGCTGCGATTGCGTGCGACGGTTACGCGCGCCGGGCGCCTGGCCTTCTTGCAACGCTTTTCGACGCCC
TCGACTGCCGTTTGCAGCGCGGCACCGGCAGCTGGCACGCGGAGTGGGCAACGCTGCGCGAGTTGGCTGCTGTCACTCAC
TCAGCAGTGAGCAGGGCTGCAACCAGCATCGATGGCATCACCGTCAACGTTGATGTGATGGCAAGTCGCGTCAATGGACC
AACCGGGCACGCCGAAGATTTGGCGGAGCGGGCACTAGAAATCTATGGAAAAGGACGCAGTTAA

Upstream 100 bases:

>100_bases
GTCCCAGCTGATCGACGTGACCTCCTGGTAGCTCAGAAGACCGATGATGGCTTCCGCTTCGACATCACTGTCCAGGCTGA
AGACAACGAAACCCCATTTT

Downstream 100 bases:

>100_bases
TGGATCGCTATGAAACCGGAATGAAAAACCGCCGCGAGGTACTGGGAGATGCCCATGTGGATCGCGCTGTGGCGAACACT
ACTGAGGTGACTGAGAAGTT

Product: hypothetical protein

Products: NA

Alternate protein names: 3-carboxymuconate lactonizing enzyme; CMLE [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MDSKLTRSLYSDLAGSGEHLSSLSDETFLKNLLVVEAALAVAAAPEHAAMAKATIDSYQLDVEELSRRAAEGGNPLIPLV
TDLKAINPAGIHIGATSQDIIDSALMLCMKEGVGEVVDKLKKLARDLAELTAEHKATPIMGRTLGQIATPTTFGALTGGW
LVAVDNATRALEALEFPVSYGGASGNMTAVHPRGFEIQAKLAEELGLFDPQWVWHSDRTPITAIASALATAAGVVRKIAG
DVVFYSQTEVGELREKSPGGSSAMPHKANPAAAIACDGYARRAPGLLATLFDALDCRLQRGTGSWHAEWATLRELAAVTH
SAVSRAATSIDGITVNVDVMASRVNGPTGHAEDLAERALEIYGKGRS

Sequences:

>Translated_367_residues
MDSKLTRSLYSDLAGSGEHLSSLSDETFLKNLLVVEAALAVAAAPEHAAMAKATIDSYQLDVEELSRRAAEGGNPLIPLV
TDLKAINPAGIHIGATSQDIIDSALMLCMKEGVGEVVDKLKKLARDLAELTAEHKATPIMGRTLGQIATPTTFGALTGGW
LVAVDNATRALEALEFPVSYGGASGNMTAVHPRGFEIQAKLAEELGLFDPQWVWHSDRTPITAIASALATAAGVVRKIAG
DVVFYSQTEVGELREKSPGGSSAMPHKANPAAAIACDGYARRAPGLLATLFDALDCRLQRGTGSWHAEWATLRELAAVTH
SAVSRAATSIDGITVNVDVMASRVNGPTGHAEDLAERALEIYGKGRS
>Mature_367_residues
MDSKLTRSLYSDLAGSGEHLSSLSDETFLKNLLVVEAALAVAAAPEHAAMAKATIDSYQLDVEELSRRAAEGGNPLIPLV
TDLKAINPAGIHIGATSQDIIDSALMLCMKEGVGEVVDKLKKLARDLAELTAEHKATPIMGRTLGQIATPTTFGALTGGW
LVAVDNATRALEALEFPVSYGGASGNMTAVHPRGFEIQAKLAEELGLFDPQWVWHSDRTPITAIASALATAAGVVRKIAG
DVVFYSQTEVGELREKSPGGSSAMPHKANPAAAIACDGYARRAPGLLATLFDALDCRLQRGTGSWHAEWATLRELAAVTH
SAVSRAATSIDGITVNVDVMASRVNGPTGHAEDLAERALEIYGKGRS

Specific function: Catalyzes an anti cycloisomerization [H]

COG id: COG0015

COG function: function code F; Adenylosuccinate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II fumarase/aspartase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019468
- InterPro:   IPR003031
- InterPro:   IPR000362
- InterPro:   IPR020557
- InterPro:   IPR008948
- InterPro:   IPR022761
- InterPro:   IPR012789 [H]

Pfam domain/function: PF10397 ADSL_C; PF00206 Lyase_1 [H]

EC number: =5.5.1.2 [H]

Molecular weight: Translated: 38558; Mature: 38558

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS00163 FUMARATE_LYASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSKLTRSLYSDLAGSGEHLSSLSDETFLKNLLVVEAALAVAAAPEHAAMAKATIDSYQL
CCHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
DVEELSRRAAEGGNPLIPLVTDLKAINPAGIHIGATSQDIIDSALMLCMKEGVGEVVDKL
CHHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
KKLARDLAELTAEHKATPIMGRTLGQIATPTTFGALTGGWLVAVDNATRALEALEFPVSY
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHCCCCEEEEECCHHHHHHHHHCCHHC
GGASGNMTAVHPRGFEIQAKLAEELGLFDPQWVWHSDRTPITAIASALATAAGVVRKIAG
CCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHC
DVVFYSQTEVGELREKSPGGSSAMPHKANPAAAIACDGYARRAPGLLATLFDALDCRLQR
CEEEECCCCHHHHHHCCCCCCCCCCCCCCCCEEEEECCHHHHCCHHHHHHHHHHHHHHHC
GTGSWHAEWATLRELAAVTHSAVSRAATSIDGITVNVDVMASRVNGPTGHAEDLAERALE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHEEEEECCCCCCCCHHHHHHHHHH
IYGKGRS
HHCCCCC
>Mature Secondary Structure
MDSKLTRSLYSDLAGSGEHLSSLSDETFLKNLLVVEAALAVAAAPEHAAMAKATIDSYQL
CCHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
DVEELSRRAAEGGNPLIPLVTDLKAINPAGIHIGATSQDIIDSALMLCMKEGVGEVVDKL
CHHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
KKLARDLAELTAEHKATPIMGRTLGQIATPTTFGALTGGWLVAVDNATRALEALEFPVSY
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHCCCCEEEEECCHHHHHHHHHCCHHC
GGASGNMTAVHPRGFEIQAKLAEELGLFDPQWVWHSDRTPITAIASALATAAGVVRKIAG
CCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHC
DVVFYSQTEVGELREKSPGGSSAMPHKANPAAAIACDGYARRAPGLLATLFDALDCRLQR
CEEEECCCCHHHHHHCCCCCCCCCCCCCCCCEEEEECCHHHHCCHHHHHHHHHHHHHHHC
GTGSWHAEWATLRELAAVTHSAVSRAATSIDGITVNVDVMASRVNGPTGHAEDLAERALE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHEEEEECCCCCCCCHHHHHHHHHH
IYGKGRS
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1390752 [H]