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The map label for this gene is betP [H]

Identifier: 145296300

GI number: 145296300

Start: 2444806

End: 2446698

Strand: Direct

Name: betP [H]

Synonym: cgR_2215

Alternate gene names: 145296300

Gene position: 2444806-2446698 (Clockwise)

Preceding gene: 145296298

Following gene: 145296302

Centisome position: 73.77

GC content: 53.09

Gene sequence:

>1893_bases
ATGTCCACCATCTCTGGCAATAACTTGCCTGAATCCCAAGAGTCAACCGAGGAACCTCATTATCCTCACGACACCCACCC
AGGCCTAGTTCCTGGCATTTCGGTCGATGATCAACGCAACAAGTTCGGACTCGACAGAACCGTTTTCGGCGTCACGGCAG
CATTAATTCTGGCGTTCATCGCCTGGGGCATTTCCAGCCCTGATTCAGTTTCTTCAGTATCGTCCACGATGTTCAGTTGG
GCTATGACGAATACTGGTTGGCTCCTCAACTTTGTCATGCTGATCGGCATTGGCACCATGCTCTACATCGCTTTTTCGCG
CTACGGCCGCATCAAGCTGGGCACAGACGAAGACGAACCAGAATTCTCTCGCTTTTCCTGGATTGCGATGATGTTCGGCG
CCGGAATCGGCGTCGGTATCTTCTTCTTCGGTCCTTCCGAACCGCTGTGGCATTATCTCAGTCCCCCACCTCACACCGTG
GAAGGATCTACACCTGAGTCCTTGCACCAAGCACTTGCGCAGTCCCACTTCCACTGGGGCTTATCCGCCTGGGGGCTGTA
TGCCTTGGTGGGCGGCGCGTTGGCGTACTCCAGTTACCGACGCGGTCGCGTAACCTTGATCAGCTCCACCTTCCGGTCAC
TTTTCGGTGAGAAAACCGAAGGTATGGCGGGTCGCCTCATCGACATGATGGCGATCATCGCCACGCTGTTTGGAACGGCT
GCAACCTTGGGCCTTTCAGCAATTCAGGTTGGTCAGGGCGTGCAGATTATTTCTGGCGCTTCGGAGATCACCAACAACAT
CTTGATGGCCATCATCGCTATCTTGACCATTGGGTTCATCATCTCCGCAGTATCTGGCGTGTCCAAGGGCATTCGTTATC
TTTCCAACCTCAATATTTCCTTGACGCTTGGATTGGTCCTGTTTGTGTTCATCACCGGCCCCACCTTGTTCCTGCTCAAC
TTGATCCCATCGAGTGTGTTGGAATATGGCAGTGAGTTCTTGTCAATGGCTGGCAAGTCTTTGTCGTGGGGTGAGGAAAC
CATTGAATTCCAAGCTGGTTGGACGGCGTTCTACTGGGCATGGTGGATCGCATGGACCCCATTCGTGGGTATGTTCATCG
CGCGTATTTCTCGCGGCCGCACCTTGCGTGAATTCGCGCTCATCACCATGGCTATCCCCTCCTTCATTTTGATCCTGGCG
TTCACCATTTTCGGTGGAACTGCCATCACGATGAACCGCGAGAACGTAGATGGTTTTGACGGCAGTTCATCCAAGGAACA
GGTGCTGTTTGATATGTTCAGCAACCTTCCGCTGTACTCGATCACACCGTTCATTTTGATCTTTGTGCTGGCAGTATTCT
TTGTTACCTCTGCCGATTCCGCCTCCGTGGTGATGGGAACGATGAGCTCCCAAGGTAACCCTGCACCAAACAAATTAATC
GTGGTGTTCTGGGGACTGTGCATGATGGGCATCGCGGTGGTCATGCTGCTTACTGGTGGCGAATCCGCGCTGACTGGTCT
GCAGAACCTCACCATTTTGATCGCCATTCCGTTTGCGCTGGTGTTGATCGTGATGGCTATTGCCTTTATTAAGGATTTAT
CCACAGACCCAGCCGCTATTCGACAACGCTATGCAAAGGCAGCCATCTCTAACGCGGTGGTTCGTGGCTTGGAAGAACAC
GGCGACGACTTCGAGCTCTCCATCGAACCTGCAGAGGAAGGTCGTGGAGCGGGTGCTACCTTCGATTCCACCGCTGATCA
CATCACCGACTGGTATCAGCGCACCGACGAAGAAGGCAATGATGTTGATTATGACTTCACCACCGGCAAATGGGCCGATG
GTTGGACACCGGAATCGACCGAAGAAGGCGAAGTAGACGCGAAAAAGGATTAA

Upstream 100 bases:

>100_bases
AAACAGGAATATTTAACTCGACTTCTTAAAAAAGCTCTATACGTAAATATCTTGCCCATCCAGCACCACCTCATTGTGGT
GCCCAATGGAGAGGACACAC

Downstream 100 bases:

>100_bases
AGAATAACGACTGGCTGGGATTCACACCATGTGAATCCCAGCTATTTTGTTTGCTCAGTGCCCTCGTGACCGTCCTATGT
GACCGATGAGGTGAGTTTCG

Product: hypothetical protein

Products: Proton [Cytoplasm]; choline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 630; Mature: 629

Protein sequence:

>630_residues
MSTISGNNLPESQESTEEPHYPHDTHPGLVPGISVDDQRNKFGLDRTVFGVTAALILAFIAWGISSPDSVSSVSSTMFSW
AMTNTGWLLNFVMLIGIGTMLYIAFSRYGRIKLGTDEDEPEFSRFSWIAMMFGAGIGVGIFFFGPSEPLWHYLSPPPHTV
EGSTPESLHQALAQSHFHWGLSAWGLYALVGGALAYSSYRRGRVTLISSTFRSLFGEKTEGMAGRLIDMMAIIATLFGTA
ATLGLSAIQVGQGVQIISGASEITNNILMAIIAILTIGFIISAVSGVSKGIRYLSNLNISLTLGLVLFVFITGPTLFLLN
LIPSSVLEYGSEFLSMAGKSLSWGEETIEFQAGWTAFYWAWWIAWTPFVGMFIARISRGRTLREFALITMAIPSFILILA
FTIFGGTAITMNRENVDGFDGSSSKEQVLFDMFSNLPLYSITPFILIFVLAVFFVTSADSASVVMGTMSSQGNPAPNKLI
VVFWGLCMMGIAVVMLLTGGESALTGLQNLTILIAIPFALVLIVMAIAFIKDLSTDPAAIRQRYAKAAISNAVVRGLEEH
GDDFELSIEPAEEGRGAGATFDSTADHITDWYQRTDEEGNDVDYDFTTGKWADGWTPESTEEGEVDAKKD

Sequences:

>Translated_630_residues
MSTISGNNLPESQESTEEPHYPHDTHPGLVPGISVDDQRNKFGLDRTVFGVTAALILAFIAWGISSPDSVSSVSSTMFSW
AMTNTGWLLNFVMLIGIGTMLYIAFSRYGRIKLGTDEDEPEFSRFSWIAMMFGAGIGVGIFFFGPSEPLWHYLSPPPHTV
EGSTPESLHQALAQSHFHWGLSAWGLYALVGGALAYSSYRRGRVTLISSTFRSLFGEKTEGMAGRLIDMMAIIATLFGTA
ATLGLSAIQVGQGVQIISGASEITNNILMAIIAILTIGFIISAVSGVSKGIRYLSNLNISLTLGLVLFVFITGPTLFLLN
LIPSSVLEYGSEFLSMAGKSLSWGEETIEFQAGWTAFYWAWWIAWTPFVGMFIARISRGRTLREFALITMAIPSFILILA
FTIFGGTAITMNRENVDGFDGSSSKEQVLFDMFSNLPLYSITPFILIFVLAVFFVTSADSASVVMGTMSSQGNPAPNKLI
VVFWGLCMMGIAVVMLLTGGESALTGLQNLTILIAIPFALVLIVMAIAFIKDLSTDPAAIRQRYAKAAISNAVVRGLEEH
GDDFELSIEPAEEGRGAGATFDSTADHITDWYQRTDEEGNDVDYDFTTGKWADGWTPESTEEGEVDAKKD
>Mature_629_residues
STISGNNLPESQESTEEPHYPHDTHPGLVPGISVDDQRNKFGLDRTVFGVTAALILAFIAWGISSPDSVSSVSSTMFSWA
MTNTGWLLNFVMLIGIGTMLYIAFSRYGRIKLGTDEDEPEFSRFSWIAMMFGAGIGVGIFFFGPSEPLWHYLSPPPHTVE
GSTPESLHQALAQSHFHWGLSAWGLYALVGGALAYSSYRRGRVTLISSTFRSLFGEKTEGMAGRLIDMMAIIATLFGTAA
TLGLSAIQVGQGVQIISGASEITNNILMAIIAILTIGFIISAVSGVSKGIRYLSNLNISLTLGLVLFVFITGPTLFLLNL
IPSSVLEYGSEFLSMAGKSLSWGEETIEFQAGWTAFYWAWWIAWTPFVGMFIARISRGRTLREFALITMAIPSFILILAF
TIFGGTAITMNRENVDGFDGSSSKEQVLFDMFSNLPLYSITPFILIFVLAVFFVTSADSASVVMGTMSSQGNPAPNKLIV
VFWGLCMMGIAVVMLLTGGESALTGLQNLTILIAIPFALVLIVMAIAFIKDLSTDPAAIRQRYAKAAISNAVVRGLEEHG
DDFELSIEPAEEGRGAGATFDSTADHITDWYQRTDEEGNDVDYDFTTGKWADGWTPESTEEGEVDAKKD

Specific function: High-affinity uptake of glycine betaine [H]

COG id: COG1292

COG function: function code M; Choline-glycine betaine transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BCCT transporter (TC 2.A.15) family [H]

Homologues:

Organism=Escherichia coli, GI1786506, Length=588, Percent_Identity=33.6734693877551, Blast_Score=305, Evalue=6e-84,
Organism=Escherichia coli, GI1788102, Length=480, Percent_Identity=28.75, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1786224, Length=511, Percent_Identity=28.5714285714286, Blast_Score=174, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000060
- InterPro:   IPR018093 [H]

Pfam domain/function: PF02028 BCCT [H]

EC number: NA

Molecular weight: Translated: 68416; Mature: 68285

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTISGNNLPESQESTEEPHYPHDTHPGLVPGISVDDQRNKFGLDRTVFGVTAALILAFI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
AWGISSPDSVSSVSSTMFSWAMTNTGWLLNFVMLIGIGTMLYIAFSRYGRIKLGTDEDEP
HHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCC
EFSRFSWIAMMFGAGIGVGIFFFGPSEPLWHYLSPPPHTVEGSTPESLHQALAQSHFHWG
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
LSAWGLYALVGGALAYSSYRRGRVTLISSTFRSLFGEKTEGMAGRLIDMMAIIATLFGTA
HHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
ATLGLSAIQVGQGVQIISGASEITNNILMAIIAILTIGFIISAVSGVSKGIRYLSNLNIS
HHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LTLGLVLFVFITGPTLFLLNLIPSSVLEYGSEFLSMAGKSLSWGEETIEFQAGWTAFYWA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHEEECCCCHHHHHH
WWIAWTPFVGMFIARISRGRTLREFALITMAIPSFILILAFTIFGGTAITMNRENVDGFD
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCC
GSSSKEQVLFDMFSNLPLYSITPFILIFVLAVFFVTSADSASVVMGTMSSQGNPAPNKLI
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHH
VVFWGLCMMGIAVVMLLTGGESALTGLQNLTILIAIPFALVLIVMAIAFIKDLSTDPAAI
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
RQRYAKAAISNAVVRGLEEHGDDFELSIEPAEEGRGAGATFDSTADHITDWYQRTDEEGN
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHCCCCCCCCCCCHHHHHHHHHHHCCCCCC
DVDYDFTTGKWADGWTPESTEEGEVDAKKD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
STISGNNLPESQESTEEPHYPHDTHPGLVPGISVDDQRNKFGLDRTVFGVTAALILAFI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
AWGISSPDSVSSVSSTMFSWAMTNTGWLLNFVMLIGIGTMLYIAFSRYGRIKLGTDEDEP
HHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCC
EFSRFSWIAMMFGAGIGVGIFFFGPSEPLWHYLSPPPHTVEGSTPESLHQALAQSHFHWG
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
LSAWGLYALVGGALAYSSYRRGRVTLISSTFRSLFGEKTEGMAGRLIDMMAIIATLFGTA
HHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
ATLGLSAIQVGQGVQIISGASEITNNILMAIIAILTIGFIISAVSGVSKGIRYLSNLNIS
HHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LTLGLVLFVFITGPTLFLLNLIPSSVLEYGSEFLSMAGKSLSWGEETIEFQAGWTAFYWA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHEEECCCCHHHHHH
WWIAWTPFVGMFIARISRGRTLREFALITMAIPSFILILAFTIFGGTAITMNRENVDGFD
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCC
GSSSKEQVLFDMFSNLPLYSITPFILIFVLAVFFVTSADSASVVMGTMSSQGNPAPNKLI
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHH
VVFWGLCMMGIAVVMLLTGGESALTGLQNLTILIAIPFALVLIVMAIAFIKDLSTDPAAI
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
RQRYAKAAISNAVVRGLEEHGDDFELSIEPAEEGRGAGATFDSTADHITDWYQRTDEEGN
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHCCCCCCCCCCCHHHHHHHHHHHCCCCCC
DVDYDFTTGKWADGWTPESTEEGEVDAKKD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; choline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + choline [Periplasm] = Proton [Cytoplasm] + choline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]