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The map label for this gene is gsiD [H]

Identifier: 145296287

GI number: 145296287

Start: 2431477

End: 2432307

Strand: Direct

Name: gsiD [H]

Synonym: cgR_2203

Alternate gene names: 145296287

Gene position: 2431477-2432307 (Clockwise)

Preceding gene: 145296286

Following gene: 145296288

Centisome position: 73.37

GC content: 55.35

Gene sequence:

>831_bases
GTGACAACGATCAAAAACATGCCCCTTTCAGGGAAAATCGGCGGCTTCATAGTTGCCGTTGTATTTGTTCTTGCTGCGCT
GTCTTTCATTTGGACTCCGTTTGATCCAGTTCAAGCTTTCCCACAGGAGCGCCTTGAGGGAAGTTCTTTGAGGCACCTGT
TGGGAACGGATCGTTATGGTCGCGATGTTTTATCCCAGATCATGGTTGGTTCCCGCGTCACGTTGTTGGTGGGCATCATT
GCGGTGGCGATCGCAGCATTAATCGGCACGCCACTGGGTATTGCTGCGGGAATGCGCCGTGGCATGGTGGAAACCTTTGT
CATGCGTGGTGCCGATTTAATGTTGGCGTTCCCAGCACTGTTGTTGGCGATTATTTCCGGCGCCGTTTTCGGCGCCTCCA
CGTGGTCCGCGATGGTCGCGATCGGCATCGCAGGCATCCCTAGTTTTGCCCGCGTGGCTCGTGCAGGCACATTGCAGGTG
ACCAGTCAGAATTTCATCGCAGCTGCTCGGCTATCAAAAGTAAGTTCCGCCCGGATCGCGCTTCGCCATATTTTGCCCAA
CATCACCAGCATTTTGATCGTTCAGGCATCAGTAGCTTTTGCCCTGGCGATCCTGGCGGAAGCCGCATTGAGTTTCCTCG
GTTTGGGCACCACTCCCCCGGATCCCAGCTGGGGTCGCATGTTGCAAACTGCTCAAGCATCCATCGGCGTCACCCCCATG
TTGGCGGTGTGGCCCGGTGCTGCGATCGCTTTGACGGTCCTTGGTTTTAATCTTTTCGGTGATGGTTTACGCGATGCCAT
CGATCCAAAGCGGGAGGTCGGCCGTGCTTAA

Upstream 100 bases:

>100_bases
GCTGGTTAATTTGGTGGTTGATCTGCTGTATCAGGTGATTGATCCAAGAGTCGGTGCTGTTGGGGTTGCTAGCACTAAGG
TTCCAGGGAGCGTGGCTTAA

Downstream 100 bases:

>100_bases
AGTTTCTGATTTAACGGTTGGCAACAATTTTGTCCACAACGTCTCCTTCGAGGTCAACCCCGGCGAACGCGTCGGCATCA
TCGGCGAGTCCGGCTCAGGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MTTIKNMPLSGKIGGFIVAVVFVLAALSFIWTPFDPVQAFPQERLEGSSLRHLLGTDRYGRDVLSQIMVGSRVTLLVGII
AVAIAALIGTPLGIAAGMRRGMVETFVMRGADLMLAFPALLLAIISGAVFGASTWSAMVAIGIAGIPSFARVARAGTLQV
TSQNFIAAARLSKVSSARIALRHILPNITSILIVQASVAFALAILAEAALSFLGLGTTPPDPSWGRMLQTAQASIGVTPM
LAVWPGAAIALTVLGFNLFGDGLRDAIDPKREVGRA

Sequences:

>Translated_276_residues
MTTIKNMPLSGKIGGFIVAVVFVLAALSFIWTPFDPVQAFPQERLEGSSLRHLLGTDRYGRDVLSQIMVGSRVTLLVGII
AVAIAALIGTPLGIAAGMRRGMVETFVMRGADLMLAFPALLLAIISGAVFGASTWSAMVAIGIAGIPSFARVARAGTLQV
TSQNFIAAARLSKVSSARIALRHILPNITSILIVQASVAFALAILAEAALSFLGLGTTPPDPSWGRMLQTAQASIGVTPM
LAVWPGAAIALTVLGFNLFGDGLRDAIDPKREVGRA
>Mature_275_residues
TTIKNMPLSGKIGGFIVAVVFVLAALSFIWTPFDPVQAFPQERLEGSSLRHLLGTDRYGRDVLSQIMVGSRVTLLVGIIA
VAIAALIGTPLGIAAGMRRGMVETFVMRGADLMLAFPALLLAIISGAVFGASTWSAMVAIGIAGIPSFARVARAGTLQVT
SQNFIAAARLSKVSSARIALRHILPNITSILIVQASVAFALAILAEAALSFLGLGTTPPDPSWGRMLQTAQASIGVTPML
AVWPGAAIALTVLGFNLFGDGLRDAIDPKREVGRA

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=239, Percent_Identity=45.1882845188285, Blast_Score=203, Evalue=8e-54,
Organism=Escherichia coli, GI1787760, Length=256, Percent_Identity=40.625, Blast_Score=171, Evalue=6e-44,
Organism=Escherichia coli, GI1789964, Length=248, Percent_Identity=44.758064516129, Blast_Score=168, Evalue=4e-43,
Organism=Escherichia coli, GI1789889, Length=240, Percent_Identity=33.3333333333333, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1787498, Length=219, Percent_Identity=39.2694063926941, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1787549, Length=230, Percent_Identity=37.8260869565217, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1788505, Length=230, Percent_Identity=30.4347826086957, Blast_Score=92, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 28790; Mature: 28658

Theoretical pI: Translated: 11.73; Mature: 11.73

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCC
>Mature Secondary Structure 
TTIKNMPLSGKIGGFIVAVVFVLAALSFIWTPFDPVQAFPQERLEGSSLRHLLGTDRYG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCHHHHHCHHHHHHHHCCCCCC
RDVLSQIMVGSRVTLLVGIIAVAIAALIGTPLGIAAGMRRGMVETFVMRGADLMLAFPAL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LLAIISGAVFGASTWSAMVAIGIAGIPSFARVARAGTLQVTSQNFIAAARLSKVSSARIA
HHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHH
LRHILPNITSILIVQASVAFALAILAEAALSFLGLGTTPPDPSWGRMLQTAQASIGVTPM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHH
LAVWPGAAIALTVLGFNLFGDGLRDAIDPKREVGRA
HHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]