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The map label for this gene is appB [H]

Identifier: 145296286

GI number: 145296286

Start: 2430508

End: 2431476

Strand: Direct

Name: appB [H]

Synonym: cgR_2202

Alternate gene names: 145296286

Gene position: 2430508-2431476 (Clockwise)

Preceding gene: 145296285

Following gene: 145296287

Centisome position: 73.34

GC content: 52.73

Gene sequence:

>969_bases
GTGAGTAAAACAATCGCTTGGACTGTGCTACGGTACACCCTGACTTTTGTGATAGCCAGCATCATCATTTTTGTGCTGAT
TCGAGTCATCCCCGGTGACCCCGCCGCTGTTGCCCTGGGAATTACCGCGACACCAGAAGCAATCGCTGCGTTGCAATCCC
AATTAGGTACTGATCAACCGCTTTTCCAACAGTATTTTTCCTGGATAGGCGGAATGCTCACTGGCGATTTCGGCACCTCG
CTGAGCTCTGGCCAAGACCTTTCCCCCATCATTTTTGACCGCTTACAAGTGAGCCTCATTTTGGTGGGATGCTCCATTGT
GTTGTCGTTGCTCATTGCCATTCCACTTGGTGTGCTTTCGGCCCGGCGCGGTGGCGTGATCGTTTCCGGCATCAGCCAGA
TTGGCATTGCGATCCCTAGTTTCCTCGCCGGTATTTTGTTGGTCGCTGTCTTCGCCGTTGGTTTGGGGTGGCTGCCTGCC
AATGGCTGGATTCCGCCGTCGGAAAACTTTGGAGTTTTCTTAGCCAGGCTGATCCTCCCGGTTCTAGCGCTTACTGCTGT
TCAAGCAGCAATTTTGACCCGCTATGTTCGCTCCGCAGTAATGGATGTCATGGGACAAGATTTCATGCGCACCGCAAGAT
CCAAAGGCATGAGCTTCAACCGTGCATTGATCGTCCATGGTCTACGCAATGCTGCTCTTCCTGTTCTCACGGTTACTGGC
TTGCAGCTGACCACCTTGGTTATCGGCGCCGTGGTGATTGAGCAAGTCTTTGTCATCCCCGGAATCGGTTCGATGCTGCT
GGAGTCCGTGTCCAACCGTGATCTCATCGCTGTGCAATCTATTGTCATGCTGCTGGTGGCGTTCACGTTGCTGGTTAATT
TGGTGGTTGATCTGCTGTATCAGGTGATTGATCCAAGAGTCGGTGCTGTTGGGGTTGCTAGCACTAAGGTTCCAGGGAGC
GTGGCTTAA

Upstream 100 bases:

>100_bases
TCGTGGTGATGTCACCAGAGATCACCGGCATTGATCCCAACGTGGTGTCCGGGGCGTTGGAATTGTCGTTGATTGGTCGG
AAAGAATCCGGGGTAGCGCA

Downstream 100 bases:

>100_bases
GTGACAACGATCAAAAACATGCCCCTTTCAGGGAAAATCGGCGGCTTCATAGTTGCCGTTGTATTTGTTCTTGCTGCGCT
GTCTTTCATTTGGACTCCGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MSKTIAWTVLRYTLTFVIASIIIFVLIRVIPGDPAAVALGITATPEAIAALQSQLGTDQPLFQQYFSWIGGMLTGDFGTS
LSSGQDLSPIIFDRLQVSLILVGCSIVLSLLIAIPLGVLSARRGGVIVSGISQIGIAIPSFLAGILLVAVFAVGLGWLPA
NGWIPPSENFGVFLARLILPVLALTAVQAAILTRYVRSAVMDVMGQDFMRTARSKGMSFNRALIVHGLRNAALPVLTVTG
LQLTTLVIGAVVIEQVFVIPGIGSMLLESVSNRDLIAVQSIVMLLVAFTLLVNLVVDLLYQVIDPRVGAVGVASTKVPGS
VA

Sequences:

>Translated_322_residues
MSKTIAWTVLRYTLTFVIASIIIFVLIRVIPGDPAAVALGITATPEAIAALQSQLGTDQPLFQQYFSWIGGMLTGDFGTS
LSSGQDLSPIIFDRLQVSLILVGCSIVLSLLIAIPLGVLSARRGGVIVSGISQIGIAIPSFLAGILLVAVFAVGLGWLPA
NGWIPPSENFGVFLARLILPVLALTAVQAAILTRYVRSAVMDVMGQDFMRTARSKGMSFNRALIVHGLRNAALPVLTVTG
LQLTTLVIGAVVIEQVFVIPGIGSMLLESVSNRDLIAVQSIVMLLVAFTLLVNLVVDLLYQVIDPRVGAVGVASTKVPGS
VA
>Mature_321_residues
SKTIAWTVLRYTLTFVIASIIIFVLIRVIPGDPAAVALGITATPEAIAALQSQLGTDQPLFQQYFSWIGGMLTGDFGTSL
SSGQDLSPIIFDRLQVSLILVGCSIVLSLLIAIPLGVLSARRGGVIVSGISQIGIAIPSFLAGILLVAVFAVGLGWLPAN
GWIPPSENFGVFLARLILPVLALTAVQAAILTRYVRSAVMDVMGQDFMRTARSKGMSFNRALIVHGLRNAALPVLTVTGL
QLTTLVIGAVVIEQVFVIPGIGSMLLESVSNRDLIAVQSIVMLLVAFTLLVNLVVDLLYQVIDPRVGAVGVASTKVPGSV
A

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=298, Percent_Identity=37.9194630872483, Blast_Score=204, Evalue=5e-54,
Organism=Escherichia coli, GI1789965, Length=321, Percent_Identity=35.202492211838, Blast_Score=198, Evalue=3e-52,
Organism=Escherichia coli, GI1789888, Length=296, Percent_Identity=35.472972972973, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI1787497, Length=312, Percent_Identity=33.6538461538462, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1787761, Length=335, Percent_Identity=34.9253731343284, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI1788504, Length=283, Percent_Identity=31.8021201413428, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1787550, Length=272, Percent_Identity=25.7352941176471, Blast_Score=105, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33870; Mature: 33739

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTIAWTVLRYTLTFVIASIIIFVLIRVIPGDPAAVALGITATPEAIAALQSQLGTDQP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCH
LFQQYFSWIGGMLTGDFGTSLSSGQDLSPIIFDRLQVSLILVGCSIVLSLLIAIPLGVLS
HHHHHHHHHCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARRGGVIVSGISQIGIAIPSFLAGILLVAVFAVGLGWLPANGWIPPSENFGVFLARLILP
CCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHH
VLALTAVQAAILTRYVRSAVMDVMGQDFMRTARSKGMSFNRALIVHGLRNAALPVLTVTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHCCH
LQLTTLVIGAVVIEQVFVIPGIGSMLLESVSNRDLIAVQSIVMLLVAFTLLVNLVVDLLY
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QVIDPRVGAVGVASTKVPGSVA
HHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SKTIAWTVLRYTLTFVIASIIIFVLIRVIPGDPAAVALGITATPEAIAALQSQLGTDQP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCCCH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HHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]