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The map label for this gene is era

Identifier: 145296239

GI number: 145296239

Start: 2379618

End: 2380103

Strand: Reverse

Name: era

Synonym: cgR_2156

Alternate gene names: 145296239

Gene position: 2380103-2379618 (Counterclockwise)

Preceding gene: 145296240

Following gene: 145296238

Centisome position: 71.82

GC content: 56.17

Gene sequence:

>486_bases
ATGGCTGTCCATGAGCTGCTCGGCGGAAACAGCGAGGTAGTCCCAGTGTCTTCCACCTCGGGGGAAAACGTCGAAACGCT
TATTAAGGTCATGACCGACCTGCTGCCTGAAGGTCCCAAGTTCTACCCGGATGATCACATCACCGATGAGGACACCAACA
CCCGCATCGCGGAAGCCATCCGCGAAGCAGCACTGTCTGGCTTGAAGAACGAACTGCCGCACTCCGTCGCAGTTGAGGTT
GATGAAATCCTGCCAGACCCAGAACGCAACGGTGTCCTGGCTGTGCACGCCATCATCTACGTCGAGCGTGTTGGTCAGAA
AGACATCATCGTCGGACACAAGGGACAGCGCCTGGGGCGCATCATCCACACCTCGCGCCAAGACATCATCAAGATCCTCG
GCCAAAACGTATTCCTTGATCTGCGCATCAAGGTGCTGAAGAACTGGCAGTCCGATCCAAAGGCTTTGAACCGCCTGGGC
TTTTAG

Upstream 100 bases:

>100_bases
GGATCCTTGAAGCAGTCCGCAGGTATCGCCTAAAACTCCTATCCTCGGCATCATCACCAAAGCAGACAGCGTCTCACGTG
ACTTGGTTGCGGCCCAACTG

Downstream 100 bases:

>100_bases
CTTTAAGGGGGTGAGTTCATGCGTAGGGACAGTTTTCGGGACCGCGCGCTAGTAGTCAAAACTCATGATTTTGGCGAAGC
CGACCGCATTATTGTGCTGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MAVHELLGGNSEVVPVSSTSGENVETLIKVMTDLLPEGPKFYPDDHITDEDTNTRIAEAIREAALSGLKNELPHSVAVEV
DEILPDPERNGVLAVHAIIYVERVGQKDIIVGHKGQRLGRIIHTSRQDIIKILGQNVFLDLRIKVLKNWQSDPKALNRLG
F

Sequences:

>Translated_161_residues
MAVHELLGGNSEVVPVSSTSGENVETLIKVMTDLLPEGPKFYPDDHITDEDTNTRIAEAIREAALSGLKNELPHSVAVEV
DEILPDPERNGVLAVHAIIYVERVGQKDIIVGHKGQRLGRIIHTSRQDIIKILGQNVFLDLRIKVLKNWQSDPKALNRLG
F
>Mature_160_residues
AVHELLGGNSEVVPVSSTSGENVETLIKVMTDLLPEGPKFYPDDHITDEDTNTRIAEAIREAALSGLKNELPHSVAVEVD
EILPDPERNGVLAVHAIIYVERVGQKDIIVGHKGQRLGRIIHTSRQDIIKILGQNVFLDLRIKVLKNWQSDPKALNRLGF

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain

Homologues:

Organism=Escherichia coli, GI1788919, Length=150, Percent_Identity=36, Blast_Score=101, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERA_CORGL (Q8NNB9)

Other databases:

- EMBL:   BA000036
- EMBL:   BX927154
- RefSeq:   NP_601485.1
- RefSeq:   YP_226528.1
- ProteinModelPortal:   Q8NNB9
- SMR:   Q8NNB9
- GeneID:   1020238
- GeneID:   3343296
- GenomeReviews:   BA000036_GR
- GenomeReviews:   BX927147_GR
- KEGG:   cgb:cg2510
- HOGENOM:   HBG561652
- OMA:   AKDWQRD
- ProtClustDB:   PRK00089
- BioCyc:   CGLU196627:CG2510-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00367
- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PRINTS:   PR00326
- TIGRFAMs:   TIGR00436
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1; SSF54814 KH_prok

EC number: NA

Molecular weight: Translated: 17828; Mature: 17696

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVHELLGGNSEVVPVSSTSGENVETLIKVMTDLLPEGPKFYPDDHITDEDTNTRIAEAI
CCCHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHH
REAALSGLKNELPHSVAVEVDEILPDPERNGVLAVHAIIYVERVGQKDIIVGHKGQRLGR
HHHHHHHHHHHCCCHHEEEHHHHCCCCCCCCEEHHHHHHHHHHCCCCCEEECCCCHHHHH
IIHTSRQDIIKILGQNVFLDLRIKVLKNWQSDPKALNRLGF
HHHCCHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHCCC
>Mature Secondary Structure 
AVHELLGGNSEVVPVSSTSGENVETLIKVMTDLLPEGPKFYPDDHITDEDTNTRIAEAI
CCHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHH
REAALSGLKNELPHSVAVEVDEILPDPERNGVLAVHAIIYVERVGQKDIIVGHKGQRLGR
HHHHHHHHHHHCCCHHEEEHHHHCCCCCCCCEEHHHHHHHHHHCCCCCEEECCCCHHHHH
IIHTSRQDIIKILGQNVFLDLRIKVLKNWQSDPKALNRLGF
HHHCCHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12948626