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The map label for this gene is 145296139

Identifier: 145296139

GI number: 145296139

Start: 2270317

End: 2271627

Strand: Direct

Name: 145296139

Synonym: cgR_2059

Alternate gene names: NA

Gene position: 2270317-2271627 (Clockwise)

Preceding gene: 145296138

Following gene: 145296142

Centisome position: 68.5

GC content: 52.56

Gene sequence:

>1311_bases
TTGACGAACCCCCAGACAGCACACGCTGCCGCGTCTGACTCCGCATCCCAGAAGGAGGCTCCTAATCCTTCACTCTCCAT
CACTGTAGGTATTAAAGATCTGCTGGGGCTGCTTTCAGTTCTTGGCATTGCAGCGGGGCTGATAGCCAACAAGATTCTCA
TCGAACGCTACAACTGGCGCATCGATGCCGCAGTTTACCGCGAAGGCGCGTTAGCGCTGGTCAACGGGCAATCACTGTAC
GCGCAGCCATTTGATATGGGTGATATTTCACTACCCTTTATCTACCCACCGATTGGTGCCATCCTGTTTGCGCCTTGGGG
GTACTTTGATTTCATCACAGTTGAACTTGCGGGAAACCTTGTTGTCATAGGCTCATCCCTGCTGTTATTACTGTGCCTGT
ATCTTGTCACCAACGCTGTTCTTAGCGGTCGAGACAAGCTGTTGGCCTTCACCATCGCTGCGATTTCCTGGCCGATCGCT
CTCTTTGCAGAGCCAGTGTTTTTGAACGCTGACTTGGGCCAAATCAACATTTTGATCATGGCTTTGGTTGTCATGGACCT
GCTTCCGATTAAGCGCAGAATCCCCCGAGGTGTCCTGATTGGCCTTGCAGCCGCCATCAAAATCACTCCGCTGGCCATGC
TGTTGTATTTCCTGGTGAAGAAGGATTTCCGCGGAATCATCAATGCGGTGATCTCACTACTTGCCTTCACGGCTATCGGT
GCTGTGCTCGCATGGGAAAACACCAAAGAGTTCTTCTCTTCAACCCTTCTCAACTTAAGTGCTGAAGGCGATTCAGGCGT
AGACACCACGTTCCAATCCAACAGCTCGATTCAGGCCATGCTGTATCGCTGGTGGACCTCAAGGGCAGATGCCGAAGCAT
CCTCACTGCCCACCATCTTGTGGATCGTACTGTCCCTGATTGCTGTGGCGGCCGTTGCCTACCTAATGCACCAACTCTTC
TCCAGAGGATTGCACGTTGAGGCAGTCATGGTTAACGCCATGCTCATGCTACTTATCTCCCCCATCTCATGGTCTCACCA
CTGGGTGTGGCTACCGCTGTGGGCTGTGGTGTTCTTCGTTCGATACCGCCAGCACCGCTCTCACCCGAAGTTCTTGTTGT
GGAGCGGAGTTATCTTGAGCGTCATGCTGCTGATGCTGCCACCAAAATGGTGGTTTGGCCGCGATGGCGTCAACGTCTTC
GAACTGAATTTCTGGGAGAAGCTACTCATCTCTGACTGGACGTGGCTCTCCATCGGGCTCATGATCACCTTGGGTCTTGG
GCTGAAAGCATTTCCCAAAATAGCCAAATAG

Upstream 100 bases:

>100_bases
CTCACTAATCGATCAGGAGTATCACATCTCCATGATTTAAGATTAAAACTTTGTCTAAACACGAACGGTGTTTTCATGTT
TAAGAAAAGGACTCCTGGTT

Downstream 100 bases:

>100_bases
ATAAAGGTGTGGGGGCTGACAACAATTGTTGTCAGCCCCCACACTTATTTCTAGAGTTGGTCTAAAAGCTTAATTACGCA
GCATTTCTGCAACGAGGAAA

Product: hypothetical protein

Products: NA

Alternate protein names: Alpha-D-mannose-alpha-(1-2)-mannosyltransferase; Alpha-mannosyltransferase; Alpha-manT; PPM-dependent mannosyltransferase; Polyprenol-phosphate-mannose alpha-mannosyltransferase; PPM alpha-mannosyltransferase [H]

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MTNPQTAHAAASDSASQKEAPNPSLSITVGIKDLLGLLSVLGIAAGLIANKILIERYNWRIDAAVYREGALALVNGQSLY
AQPFDMGDISLPFIYPPIGAILFAPWGYFDFITVELAGNLVVIGSSLLLLLCLYLVTNAVLSGRDKLLAFTIAAISWPIA
LFAEPVFLNADLGQINILIMALVVMDLLPIKRRIPRGVLIGLAAAIKITPLAMLLYFLVKKDFRGIINAVISLLAFTAIG
AVLAWENTKEFFSSTLLNLSAEGDSGVDTTFQSNSSIQAMLYRWWTSRADAEASSLPTILWIVLSLIAVAAVAYLMHQLF
SRGLHVEAVMVNAMLMLLISPISWSHHWVWLPLWAVVFFVRYRQHRSHPKFLLWSGVILSVMLLMLPPKWWFGRDGVNVF
ELNFWEKLLISDWTWLSIGLMITLGLGLKAFPKIAK

Sequences:

>Translated_436_residues
MTNPQTAHAAASDSASQKEAPNPSLSITVGIKDLLGLLSVLGIAAGLIANKILIERYNWRIDAAVYREGALALVNGQSLY
AQPFDMGDISLPFIYPPIGAILFAPWGYFDFITVELAGNLVVIGSSLLLLLCLYLVTNAVLSGRDKLLAFTIAAISWPIA
LFAEPVFLNADLGQINILIMALVVMDLLPIKRRIPRGVLIGLAAAIKITPLAMLLYFLVKKDFRGIINAVISLLAFTAIG
AVLAWENTKEFFSSTLLNLSAEGDSGVDTTFQSNSSIQAMLYRWWTSRADAEASSLPTILWIVLSLIAVAAVAYLMHQLF
SRGLHVEAVMVNAMLMLLISPISWSHHWVWLPLWAVVFFVRYRQHRSHPKFLLWSGVILSVMLLMLPPKWWFGRDGVNVF
ELNFWEKLLISDWTWLSIGLMITLGLGLKAFPKIAK
>Mature_435_residues
TNPQTAHAAASDSASQKEAPNPSLSITVGIKDLLGLLSVLGIAAGLIANKILIERYNWRIDAAVYREGALALVNGQSLYA
QPFDMGDISLPFIYPPIGAILFAPWGYFDFITVELAGNLVVIGSSLLLLLCLYLVTNAVLSGRDKLLAFTIAAISWPIAL
FAEPVFLNADLGQINILIMALVVMDLLPIKRRIPRGVLIGLAAAIKITPLAMLLYFLVKKDFRGIINAVISLLAFTAIGA
VLAWENTKEFFSSTLLNLSAEGDSGVDTTFQSNSSIQAMLYRWWTSRADAEASSLPTILWIVLSLIAVAAVAYLMHQLFS
RGLHVEAVMVNAMLMLLISPISWSHHWVWLPLWAVVFFVRYRQHRSHPKFLLWSGVILSVMLLMLPPKWWFGRDGVNVFE
LNFWEKLLISDWTWLSIGLMITLGLGLKAFPKIAK

Specific function: Responsible for the addition of alpha-(1-2) mannose branches to the linear mannan core on the biosynthetic pathway to mature Lipoarabinomannan (LAM) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018584 [H]

Pfam domain/function: PF09594 DUF2029 [H]

EC number: NA

Molecular weight: Translated: 48192; Mature: 48061

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: PS00221 MIP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNPQTAHAAASDSASQKEAPNPSLSITVGIKDLLGLLSVLGIAAGLIANKILIERYNWR
CCCCCCCHHHCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
IDAAVYREGALALVNGQSLYAQPFDMGDISLPFIYPPIGAILFAPWGYFDFITVELAGNL
EEHHHHCCCCEEEEECCEEEECCCCCCCCCCCEECCCHHHHHCCCCCHHHEEEEEECCCE
VVIGSSLLLLLCLYLVTNAVLSGRDKLLAFTIAAISWPIALFAEPVFLNADLGQINILIM
EEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHH
ALVVMDLLPIKRRIPRGVLIGLAAAIKITPLAMLLYFLVKKDFRGIINAVISLLAFTAIG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVLAWENTKEFFSSTLLNLSAEGDSGVDTTFQSNSSIQAMLYRWWTSRADAEASSLPTIL
HHHCCCCHHHHHHHHHHEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHCCHHHH
WIVLSLIAVAAVAYLMHQLFSRGLHVEAVMVNAMLMLLISPISWSHHWVWLPLWAVVFFV
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
RYRQHRSHPKFLLWSGVILSVMLLMLPPKWWFGRDGVNVFELNFWEKLLISDWTWLSIGL
HHHHHCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHCCCHHHHHHH
MITLGLGLKAFPKIAK
HHHHCCCHHHCCCCCC
>Mature Secondary Structure 
TNPQTAHAAASDSASQKEAPNPSLSITVGIKDLLGLLSVLGIAAGLIANKILIERYNWR
CCCCCCHHHCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
IDAAVYREGALALVNGQSLYAQPFDMGDISLPFIYPPIGAILFAPWGYFDFITVELAGNL
EEHHHHCCCCEEEEECCEEEECCCCCCCCCCCEECCCHHHHHCCCCCHHHEEEEEECCCE
VVIGSSLLLLLCLYLVTNAVLSGRDKLLAFTIAAISWPIALFAEPVFLNADLGQINILIM
EEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHH
ALVVMDLLPIKRRIPRGVLIGLAAAIKITPLAMLLYFLVKKDFRGIINAVISLLAFTAIG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVLAWENTKEFFSSTLLNLSAEGDSGVDTTFQSNSSIQAMLYRWWTSRADAEASSLPTIL
HHHCCCCHHHHHHHHHHEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHCCHHHH
WIVLSLIAVAAVAYLMHQLFSRGLHVEAVMVNAMLMLLISPISWSHHWVWLPLWAVVFFV
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
RYRQHRSHPKFLLWSGVILSVMLLMLPPKWWFGRDGVNVFELNFWEKLLISDWTWLSIGL
HHHHHCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHCCCHHHHHHH
MITLGLGLKAFPKIAK
HHHHCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]