| Definition | Corynebacterium glutamicum R chromosome, complete genome. |
|---|---|
| Accession | NC_009342 |
| Length | 3,314,179 |
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The map label for this gene is mutA [H]
Identifier: 145295661
GI number: 145295661
Start: 1757503
End: 1759353
Strand: Reverse
Name: mutA [H]
Synonym: cgR_1588
Alternate gene names: 145295661
Gene position: 1759353-1757503 (Counterclockwise)
Preceding gene: 145295664
Following gene: 145295660
Centisome position: 53.09
GC content: 54.73
Gene sequence:
>1851_bases TTGACTGATCTCACAAAGACTGCGGTGCCCGAGGAACTTTCAGAGAACCTCGAAACTTGGTACAAGGCTGTGGCCGGTGT TTTCGCGCGCACACAGAAGAAAGACATCGGCGACATTGCCGTAGATGTGTGGAAGAAACTCATCGTCACTACACCGGATG GTGTTGATATCAATCCGCTGTACACCAGAGCAGATGAGTCCCAGAGGAAATTCACTGAGGTTCCTGGTGAGTTTCCCTTC ACTAGGGGAACCACTGTTGATGGTGAACGTGTTGGTTGGGGTGTTACTGAGACTTTCGGACATGACAGCCCGAAGAATAT CAACGCTGCGGTGCTGCATGCTCTGAATTCTGGCACCACCACATTGGGTTTTGAGTTCTCCGAGGAATTCACGGCAGCTG ATCTTAAAGTTGCTCTCGAAGGCGTGTATCTCAACATGGCTCCGTTGCTGATTCATGCGGGTGGATCCACGTCAGAGGTT GCAGCGGCGTTGTATGCGTTGGCGGAGGAAGCCGGAACGCCTTTTGCTGCGTTGACCTTGGGTTCTCGTCCTTTGACGGC GCAGGTTGATGGTTCGCACAGTGACACCATTGAAGAAGCAGTTCAGTTGGCAGTGAATGCTTCCAAGCGTGCGAATGTGC GCGCTATCTTGGTGGATGGTTCCAGTTTTTCCAACCAGGGCGCGTCGGATGCTCAAGAAATTGGTCTAAGTATCGCCGCC GGTGTGGATTATGTCCGTCGCTTGGTCGATGCAGGCCTTTCCATGGAAGCTGCACTTAAGCAGGTGGCGTTCCGTTTTGC GGTCACCGATGAGCAGTTCGCGCAGATTTCTAAGCTGCGTGTGGCTCGACGTCTGTGGGCCAGGGTGTGTGAGGTGCTTG GTTTTCCAGAGCTGGCCGTAGCACCACAACATGCGGTGACTGCACGAGCGATGTTTAGCCAGCGTGATCCGTGGGTGAAT ATGCTGCGCAGTACTGTTGCAGCTTTCGCTGCAGGCGTCGGTGGAGCAACCGATGTGGAGGTTCGTACTTTTGATGATGC GATCCCAGGTGGAGTTCCTGGAGTGTCGAGGAATTTCGCTCACCGCATCGCGCGCAATACTAATTTGTTGTTGCTTGAAG AGTCACATCTTGGTCACGTGGTTGATCCTGCTGGTGGATCATATTTCGTGGAGAGCTTCACCGATGATCTAGCGGAGAAG GCGTGGGCTGTGTTCAGTGGCATCGAAGCTGAGGGCGGATACAGTGCAGCTTGTGCATCCGGCACGGTGACAGCCATGCT TGATCAGACGTGGGAGCAGACTCGCGCTGATGTGGCGTCGAGAAAGAAGAAGCTCACTGGAATTAATGAGTTCCCGAACT TGGCGGAGTCTCCGCTGCCAGCTGATCGTCGGGTAGAACCTGCGGGTGTGCGTCGATGGGCAGCGGATTTTGAAGCGCTG CGCAATCGTTCGGATGCTTTCTTGGAAAAGAACGGCGCGAGGCCACAGATCACGATGATTCCTCTGGGACCGTTGTCCAA GCACAATATTCGCACTGGTTTTACTTCCAACCTGTTGGCTTCCGGTGGCATTGAAGCAATCAACCCGGGTCAACTTGTTC CCGGCACTGACTCTTTTGCAGAAGCTGCACAGGCCGCAGGCATTGTAGTGGTGTGTGGAACGGACCAAGAGTATGCCGAA ACGGGGGAGGGAGCCGTCGAAAAGCTCCGCGAAGCGGGCGTTGAGCGCATCCTGCTTGCTGGCGCGCCGAAGAGCTTTGA GGGCAGCGCGCATGCGCCCGATGGTTATTTGAACATGACAATTGATGCCGCGGCGACGCTGGCTGACCTGCTAGATGCTT TGGGAGCTTAA
Upstream 100 bases:
>100_bases CTTTCGTAGGTAAACACAGGTGAAGGCTTTGCAAGCTTGTGAACTCCCTACACAAAAGCAATCCAATAGCTATCCATAAG CAAGAGAAAGTAAGTCTACG
Downstream 100 bases:
>100_bases ATCATGACGTCGATCCCTAATTTTTCAGACATCCCATTGGCTGCAGAGACACATGCATCGGAGTCACACAACGTTGACGC CGGCAAGGTGTGGAACACTC
Product: hypothetical protein
Products: NA
Alternate protein names: MCM [H]
Number of amino acids: Translated: 616; Mature: 615
Protein sequence:
>616_residues MTDLTKTAVPEELSENLETWYKAVAGVFARTQKKDIGDIAVDVWKKLIVTTPDGVDINPLYTRADESQRKFTEVPGEFPF TRGTTVDGERVGWGVTETFGHDSPKNINAAVLHALNSGTTTLGFEFSEEFTAADLKVALEGVYLNMAPLLIHAGGSTSEV AAALYALAEEAGTPFAALTLGSRPLTAQVDGSHSDTIEEAVQLAVNASKRANVRAILVDGSSFSNQGASDAQEIGLSIAA GVDYVRRLVDAGLSMEAALKQVAFRFAVTDEQFAQISKLRVARRLWARVCEVLGFPELAVAPQHAVTARAMFSQRDPWVN MLRSTVAAFAAGVGGATDVEVRTFDDAIPGGVPGVSRNFAHRIARNTNLLLLEESHLGHVVDPAGGSYFVESFTDDLAEK AWAVFSGIEAEGGYSAACASGTVTAMLDQTWEQTRADVASRKKKLTGINEFPNLAESPLPADRRVEPAGVRRWAADFEAL RNRSDAFLEKNGARPQITMIPLGPLSKHNIRTGFTSNLLASGGIEAINPGQLVPGTDSFAEAAQAAGIVVVCGTDQEYAE TGEGAVEKLREAGVERILLAGAPKSFEGSAHAPDGYLNMTIDAAATLADLLDALGA
Sequences:
>Translated_616_residues MTDLTKTAVPEELSENLETWYKAVAGVFARTQKKDIGDIAVDVWKKLIVTTPDGVDINPLYTRADESQRKFTEVPGEFPF TRGTTVDGERVGWGVTETFGHDSPKNINAAVLHALNSGTTTLGFEFSEEFTAADLKVALEGVYLNMAPLLIHAGGSTSEV AAALYALAEEAGTPFAALTLGSRPLTAQVDGSHSDTIEEAVQLAVNASKRANVRAILVDGSSFSNQGASDAQEIGLSIAA GVDYVRRLVDAGLSMEAALKQVAFRFAVTDEQFAQISKLRVARRLWARVCEVLGFPELAVAPQHAVTARAMFSQRDPWVN MLRSTVAAFAAGVGGATDVEVRTFDDAIPGGVPGVSRNFAHRIARNTNLLLLEESHLGHVVDPAGGSYFVESFTDDLAEK AWAVFSGIEAEGGYSAACASGTVTAMLDQTWEQTRADVASRKKKLTGINEFPNLAESPLPADRRVEPAGVRRWAADFEAL RNRSDAFLEKNGARPQITMIPLGPLSKHNIRTGFTSNLLASGGIEAINPGQLVPGTDSFAEAAQAAGIVVVCGTDQEYAE TGEGAVEKLREAGVERILLAGAPKSFEGSAHAPDGYLNMTIDAAATLADLLDALGA >Mature_615_residues TDLTKTAVPEELSENLETWYKAVAGVFARTQKKDIGDIAVDVWKKLIVTTPDGVDINPLYTRADESQRKFTEVPGEFPFT RGTTVDGERVGWGVTETFGHDSPKNINAAVLHALNSGTTTLGFEFSEEFTAADLKVALEGVYLNMAPLLIHAGGSTSEVA AALYALAEEAGTPFAALTLGSRPLTAQVDGSHSDTIEEAVQLAVNASKRANVRAILVDGSSFSNQGASDAQEIGLSIAAG VDYVRRLVDAGLSMEAALKQVAFRFAVTDEQFAQISKLRVARRLWARVCEVLGFPELAVAPQHAVTARAMFSQRDPWVNM LRSTVAAFAAGVGGATDVEVRTFDDAIPGGVPGVSRNFAHRIARNTNLLLLEESHLGHVVDPAGGSYFVESFTDDLAEKA WAVFSGIEAEGGYSAACASGTVTAMLDQTWEQTRADVASRKKKLTGINEFPNLAESPLPADRRVEPAGVRRWAADFEALR NRSDAFLEKNGARPQITMIPLGPLSKHNIRTGFTSNLLASGGIEAINPGQLVPGTDSFAEAAQAAGIVVVCGTDQEYAET GEGAVEKLREAGVERILLAGAPKSFEGSAHAPDGYLNMTIDAAATLADLLDALGA
Specific function: Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates [H]
COG id: COG1884
COG function: function code I; Methylmalonyl-CoA mutase, N-terminal domain/subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the methylmalonyl-CoA mutase family [H]
Homologues:
Organism=Homo sapiens, GI156105689, Length=480, Percent_Identity=25.8333333333333, Blast_Score=146, Evalue=7e-35, Organism=Escherichia coli, GI1789284, Length=475, Percent_Identity=25.4736842105263, Blast_Score=152, Evalue=8e-38, Organism=Caenorhabditis elegans, GI25144500, Length=444, Percent_Identity=27.7027027027027, Blast_Score=169, Evalue=5e-42,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR016176 - InterPro: IPR014348 - InterPro: IPR006158 - InterPro: IPR006099 - InterPro: IPR004608 [H]
Pfam domain/function: PF01642 MM_CoA_mutase [H]
EC number: =5.4.99.2 [H]
Molecular weight: Translated: 65364; Mature: 65233
Theoretical pI: Translated: 4.62; Mature: 4.62
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 1.3 %Met (Translated Protein) 1.8 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 1.1 %Met (Mature Protein) 1.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTDLTKTAVPEELSENLETWYKAVAGVFARTQKKDIGDIAVDVWKKLIVTTPDGVDINPL CCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEECCCCCCCCCC YTRADESQRKFTEVPGEFPFTRGTTVDGERVGWGVTETFGHDSPKNINAAVLHALNSGTT CCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHCCCCE TLGFEFSEEFTAADLKVALEGVYLNMAPLLIHAGGSTSEVAAALYALAEEAGTPFAALTL EEEEECCCHHHHHHHHHHHHHHEEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEE GSRPLTAQVDGSHSDTIEEAVQLAVNASKRANVRAILVDGSSFSNQGASDAQEIGLSIAA CCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCHHHHHCHHHHH GVDYVRRLVDAGLSMEAALKQVAFRFAVTDEQFAQISKLRVARRLWARVCEVLGFPELAV HHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHC APQHAVTARAMFSQRDPWVNMLRSTVAAFAAGVGGATDVEVRTFDDAIPGGVPGVSRNFA CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHHH HRIARNTNLLLLEESHLGHVVDPAGGSYFVESFTDDLAEKAWAVFSGIEAEGGYSAACAS HHHHCCCCEEEEECCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCC GTVTAMLDQTWEQTRADVASRKKKLTGINEFPNLAESPLPADRRVEPAGVRRWAADFEAL CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH RNRSDAFLEKNGARPQITMIPLGPLSKHNIRTGFTSNLLASGGIEAINPGQLVPGTDSFA HCCCHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHH EAAQAAGIVVVCGTDQEYAETGEGAVEKLREAGVERILLAGAPKSFEGSAHAPDGYLNMT HHHHHCCEEEEECCCHHHHHCCCHHHHHHHHCCHHEEEEECCCCCCCCCCCCCCCEEEEE IDAAATLADLLDALGA HHHHHHHHHHHHHHCC >Mature Secondary Structure TDLTKTAVPEELSENLETWYKAVAGVFARTQKKDIGDIAVDVWKKLIVTTPDGVDINPL CCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEECCCCCCCCCC YTRADESQRKFTEVPGEFPFTRGTTVDGERVGWGVTETFGHDSPKNINAAVLHALNSGTT CCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHCCCCE TLGFEFSEEFTAADLKVALEGVYLNMAPLLIHAGGSTSEVAAALYALAEEAGTPFAALTL EEEEECCCHHHHHHHHHHHHHHEEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEE GSRPLTAQVDGSHSDTIEEAVQLAVNASKRANVRAILVDGSSFSNQGASDAQEIGLSIAA CCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCHHHHHCHHHHH GVDYVRRLVDAGLSMEAALKQVAFRFAVTDEQFAQISKLRVARRLWARVCEVLGFPELAV HHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHC APQHAVTARAMFSQRDPWVNMLRSTVAAFAAGVGGATDVEVRTFDDAIPGGVPGVSRNFA CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHHH HRIARNTNLLLLEESHLGHVVDPAGGSYFVESFTDDLAEKAWAVFSGIEAEGGYSAACAS HHHHCCCCEEEEECCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCC GTVTAMLDQTWEQTRADVASRKKKLTGINEFPNLAESPLPADRRVEPAGVRRWAADFEAL CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH RNRSDAFLEKNGARPQITMIPLGPLSKHNIRTGFTSNLLASGGIEAINPGQLVPGTDSFA HCCCHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCHHH EAAQAAGIVVVCGTDQEYAETGEGAVEKLREAGVERILLAGAPKSFEGSAHAPDGYLNMT HHHHHCCEEEEECCCHHHHHCCCHHHHHHHHCCHHEEEEECCCCCCCCCCCCCCCEEEEE IDAAATLADLLDALGA HHHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12788972 [H]