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The map label for this gene is argB

Identifier: 145295531

GI number: 145295531

Start: 1612355

End: 1613308

Strand: Direct

Name: argB

Synonym: cgR_1459

Alternate gene names: 145295531

Gene position: 1612355-1613308 (Clockwise)

Preceding gene: 145295530

Following gene: 145295532

Centisome position: 48.65

GC content: 53.88

Gene sequence:

>954_bases
ATGAATGACTTGATCAAAGATTTAGGCTCTGAGGTGCGCGCAAATGTCCTCGCTGAGGCGTTGCCATGGTTGCAGCACTT
CCGCGACAAGATTGTTGTCGTGAAATATGGCGGAAACGCCATGGTGGATGATGATCTCAAGGCTGCTTTTGCTGCCGACA
TGGTCTTCTTGCGCACCGTGGGCGCAAAACCAGTGGTGGTGCACGGTGGTGGACCTCAGATTTCTGAGATGCTAAACCGT
GTGGGTCTCCAGGGCGAGTTCAAGGGTGGTTTCCGTGTGACCACTCCTGAGGTCATGGACATTGTGCGCATGGTGCTCTT
TGGTCAGGTCGGTCGCGATTTAGTTGGTTTGATCAACTCTCATGGCCCTTACGCTGTGGGAACCTCCGGTGAGGATGCCG
GCCTGTTTACCGCGCAGAAGCGCATGGTCAACATCGATGGCGTACCCACTGATATTGGTTTGGTCGGAGACATCATTAAT
GTCGATGCCTCTTCCTTGATGGATATCATCGAGGCCGGTCGCATTCCTGTGGTCTCTACGATTGCTCCAGGCGAAGACGG
CCAGATTTACAACATCAACGCCGATACCGCAGCGGGTGCTTTGGCTGCAGCGATTGGTGCAGAACGCCTGCTGGTTCTCA
CCAATGTGGAAGGTCTGTACACCGATTGGCCTGATAAGAGCTCACTGGTGTCCAAGATCAAGGCCACCGAGCTGGAGGCC
ATTCTTCCGGGACTTGATTCCGGCATGATTCCAAAGATGGAGTCTTGCTTGAACGCGGTGCGTGGGGGAGTAAGCGCTGC
TCATGTCATTGACGGCCGCATCGCGCACTCGGTGTTGCTGGAGCTTTTGACCATGGGTGGAATTGGCACGATGGTGCTGC
CGGATGTTTTTGATCGGGAGAATTATCCTGAAGGCACCGTTTTTAGAAAAGACGACAAGGATGGGGAACTGTAA

Upstream 100 bases:

>100_bases
AACCACTGACCTGAGCTTCTCCTACGTGGAGATCAACTCCGCGTACAGCACTTAAAAAGAAACAACACTCCAACTAACAA
GCAGGGAAAAGGGCACAGGC

Downstream 100 bases:

>100_bases
ATGAGCACGCTGGAAACTTGGCCACAGGTCATTATTAATACGTACGGCACCCCTCCAGTTGAGCTGGTGTCCGGCAAGGG
CGCAACCGTCACTGATGACC

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MNDLIKDLGSEVRANVLAEALPWLQHFRDKIVVVKYGGNAMVDDDLKAAFAADMVFLRTVGAKPVVVHGGGPQISEMLNR
VGLQGEFKGGFRVTTPEVMDIVRMVLFGQVGRDLVGLINSHGPYAVGTSGEDAGLFTAQKRMVNIDGVPTDIGLVGDIIN
VDASSLMDIIEAGRIPVVSTIAPGEDGQIYNINADTAAGALAAAIGAERLLVLTNVEGLYTDWPDKSSLVSKIKATELEA
ILPGLDSGMIPKMESCLNAVRGGVSAAHVIDGRIAHSVLLELLTMGGIGTMVLPDVFDRENYPEGTVFRKDDKDGEL

Sequences:

>Translated_317_residues
MNDLIKDLGSEVRANVLAEALPWLQHFRDKIVVVKYGGNAMVDDDLKAAFAADMVFLRTVGAKPVVVHGGGPQISEMLNR
VGLQGEFKGGFRVTTPEVMDIVRMVLFGQVGRDLVGLINSHGPYAVGTSGEDAGLFTAQKRMVNIDGVPTDIGLVGDIIN
VDASSLMDIIEAGRIPVVSTIAPGEDGQIYNINADTAAGALAAAIGAERLLVLTNVEGLYTDWPDKSSLVSKIKATELEA
ILPGLDSGMIPKMESCLNAVRGGVSAAHVIDGRIAHSVLLELLTMGGIGTMVLPDVFDRENYPEGTVFRKDDKDGEL
>Mature_317_residues
MNDLIKDLGSEVRANVLAEALPWLQHFRDKIVVVKYGGNAMVDDDLKAAFAADMVFLRTVGAKPVVVHGGGPQISEMLNR
VGLQGEFKGGFRVTTPEVMDIVRMVLFGQVGRDLVGLINSHGPYAVGTSGEDAGLFTAQKRMVNIDGVPTDIGLVGDIIN
VDASSLMDIIEAGRIPVVSTIAPGEDGQIYNINADTAAGALAAAIGAERLLVLTNVEGLYTDWPDKSSLVSKIKATELEA
ILPGLDSGMIPKMESCLNAVRGGVSAAHVIDGRIAHSVLLELLTMGGIGTMVLPDVFDRENYPEGTVFRKDDKDGEL

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI145693208, Length=233, Percent_Identity=29.6137339055794, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789181, Length=284, Percent_Identity=23.2394366197183, Blast_Score=73, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320913, Length=206, Percent_Identity=31.0679611650485, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGB_CORGB (A4QDZ0)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001138352.1
- ProteinModelPortal:   A4QDZ0
- SMR:   A4QDZ0
- STRING:   A4QDZ0
- GeneID:   4992990
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_1459
- eggNOG:   COG0548
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- ProtClustDB:   PRK00942
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- PRINTS:   PR00474
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 33609; Mature: 33609

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: BINDING 92-92 BINDING 191-191

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDLIKDLGSEVRANVLAEALPWLQHFRDKIVVVKYGGNAMVDDDLKAAFAADMVFLRTV
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEECHHHHHHHHHHHHHHHHC
GAKPVVVHGGGPQISEMLNRVGLQGEFKGGFRVTTPEVMDIVRMVLFGQVGRDLVGLINS
CCCEEEEECCCHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHC
HGPYAVGTSGEDAGLFTAQKRMVNIDGVPTDIGLVGDIINVDASSLMDIIEAGRIPVVST
CCCEEECCCCCCCCEEHHHHHEEECCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCEEEE
IAPGEDGQIYNINADTAAGALAAAIGAERLLVLTNVEGLYTDWPDKSSLVSKIKATELEA
ECCCCCCEEEEECCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
ILPGLDSGMIPKMESCLNAVRGGVSAAHVIDGRIAHSVLLELLTMGGIGTMVLPDVFDRE
HHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHCCC
NYPEGTVFRKDDKDGEL
CCCCCCEEECCCCCCCC
>Mature Secondary Structure
MNDLIKDLGSEVRANVLAEALPWLQHFRDKIVVVKYGGNAMVDDDLKAAFAADMVFLRTV
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEECHHHHHHHHHHHHHHHHC
GAKPVVVHGGGPQISEMLNRVGLQGEFKGGFRVTTPEVMDIVRMVLFGQVGRDLVGLINS
CCCEEEEECCCHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHC
HGPYAVGTSGEDAGLFTAQKRMVNIDGVPTDIGLVGDIINVDASSLMDIIEAGRIPVVST
CCCEEECCCCCCCCEEHHHHHEEECCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCEEEE
IAPGEDGQIYNINADTAAGALAAAIGAERLLVLTNVEGLYTDWPDKSSLVSKIKATELEA
ECCCCCCEEEEECCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
ILPGLDSGMIPKMESCLNAVRGGVSAAHVIDGRIAHSVLLELLTMGGIGTMVLPDVFDRE
HHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHCCC
NYPEGTVFRKDDKDGEL
CCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA