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The map label for this gene is argC

Identifier: 145295529

GI number: 145295529

Start: 1610016

End: 1611059

Strand: Direct

Name: argC

Synonym: cgR_1457

Alternate gene names: 145295529

Gene position: 1610016-1611059 (Clockwise)

Preceding gene: 145295528

Following gene: 145295530

Centisome position: 48.58

GC content: 53.35

Gene sequence:

>1044_bases
ATGACAATCAAGGTTGCAATCGCAGGAGCCAGTGGATATGCCGGCGGAGAAATCCTTCGTCTCCTTTTAGGCCATCCAGC
TTATGCATCTGGTGAACTAGAAATCGGAGCACTCACCGCGGCATCAACCGCAGGCAGCACGCTCGGTGAATTGATGCCAC
ACATTCCGCAGTTGGCGGATCGTGTTATTCAAGACACCACAGCTGAAACTCTAGCCGGTCATGATGTCGTATTTCTAGGA
CTTCCACACGGATTCTCTGCAGAAATTGCACTTCAGCTCGGACCAGATGTCACAGTGATTGACTGTGCAGCTGACTTTCG
TCTGCAAAATGCTGCAGATTGGGAGAAGTTCTACGGCTCAGAGCACCAGGGAACATGGCCTTATGGCATTCCAGAAATGC
CAGGACACCGCGAGGCTCTTCGTGGTGCTAAGCGTGTAGCAGTGCCAGGATGTTTCCCAACCGGTGCAACCTTGGCTCTT
ATTCCTGCGGTTCAAGCGGGACTTATCGAGCCAGATGTTTCCGTCGTGTCCATCACCGGCGTATCAGGTGGAGGTAAGAA
AGCATCTGTTGCACTACTTGGCTCGGAAACCATGGGTTCACTCAAGGCGTATAACACCTCCGGAAAGCACCGCCACACCC
CGGAAATTGCCCAGAACCTCGGCGAAGTCAGCGACAAGCCAGTCAAGGTGAGCTTCACCCCAGTGCTTGCACCGTTACCT
CGCGGAATTCTCACCACTGCAACCGCACCTTTGAAAGAAGGCGTTACCGCAGAACAGGCTCGCGCAGTATATGAAGAGTT
CTATGCACAGGAAACCTTCGTGCATGTTCTTCCAGAAGGTGCACAGCCACAAACCCAAGCAGTTCTTGGCTCCAACATGT
GCCACGTGCAGGTAGAAATCGATGAGGAAGCAGGCAAAGTCCTTGTTACCTCCGCAATCGATAACCTCACCAAGGGAACT
GCCGGCGCCGCTGTTCAGTGCATGAACTTAAGCGTTGGTTTTGATGAGGCAGCAGGCCTGCCACAGGTCGGCGTCGCACC
TTAA

Upstream 100 bases:

>100_bases
TTTGCATGTCTAACCCGTCTTTTATGCACATCCTCGCAATGAATCAAAAAATTCTTCATGAATAATTTGCACGATCATGC
ATAACGTGTATGGTGTAACT

Downstream 100 bases:

>100_bases
AGTAGCGCCTTAAAGCGGCGCTTCAAACCAAGCGCCTTAACCAACAAGCACAACAAACACATCTAATTCAGTAGGAGTTC
CACATGGCAGAAAAAGGCAT

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MTIKVAIAGASGYAGGEILRLLLGHPAYASGELEIGALTAASTAGSTLGELMPHIPQLADRVIQDTTAETLAGHDVVFLG
LPHGFSAEIALQLGPDVTVIDCAADFRLQNAADWEKFYGSEHQGTWPYGIPEMPGHREALRGAKRVAVPGCFPTGATLAL
IPAVQAGLIEPDVSVVSITGVSGGGKKASVALLGSETMGSLKAYNTSGKHRHTPEIAQNLGEVSDKPVKVSFTPVLAPLP
RGILTTATAPLKEGVTAEQARAVYEEFYAQETFVHVLPEGAQPQTQAVLGSNMCHVQVEIDEEAGKVLVTSAIDNLTKGT
AGAAVQCMNLSVGFDEAAGLPQVGVAP

Sequences:

>Translated_347_residues
MTIKVAIAGASGYAGGEILRLLLGHPAYASGELEIGALTAASTAGSTLGELMPHIPQLADRVIQDTTAETLAGHDVVFLG
LPHGFSAEIALQLGPDVTVIDCAADFRLQNAADWEKFYGSEHQGTWPYGIPEMPGHREALRGAKRVAVPGCFPTGATLAL
IPAVQAGLIEPDVSVVSITGVSGGGKKASVALLGSETMGSLKAYNTSGKHRHTPEIAQNLGEVSDKPVKVSFTPVLAPLP
RGILTTATAPLKEGVTAEQARAVYEEFYAQETFVHVLPEGAQPQTQAVLGSNMCHVQVEIDEEAGKVLVTSAIDNLTKGT
AGAAVQCMNLSVGFDEAAGLPQVGVAP
>Mature_346_residues
TIKVAIAGASGYAGGEILRLLLGHPAYASGELEIGALTAASTAGSTLGELMPHIPQLADRVIQDTTAETLAGHDVVFLGL
PHGFSAEIALQLGPDVTVIDCAADFRLQNAADWEKFYGSEHQGTWPYGIPEMPGHREALRGAKRVAVPGCFPTGATLALI
PAVQAGLIEPDVSVVSITGVSGGGKKASVALLGSETMGSLKAYNTSGKHRHTPEIAQNLGEVSDKPVKVSFTPVLAPLPR
GILTTATAPLKEGVTAEQARAVYEEFYAQETFVHVLPEGAQPQTQAVLGSNMCHVQVEIDEEAGKVLVTSAIDNLTKGTA
GAAVQCMNLSVGFDEAAGLPQVGVAP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=353, Percent_Identity=36.2606232294618, Blast_Score=170, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6320913, Length=345, Percent_Identity=27.536231884058, Blast_Score=114, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_CORGB (A4QDY8)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001138350.1
- ProteinModelPortal:   A4QDY8
- SMR:   A4QDY8
- STRING:   A4QDY8
- GeneID:   4993011
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_1457
- eggNOG:   COG0002
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- ProtClustDB:   PRK00436
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 35874; Mature: 35743

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 151-151

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKVAIAGASGYAGGEILRLLLGHPAYASGELEIGALTAASTAGSTLGELMPHIPQLAD
CEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHH
RVIQDTTAETLAGHDVVFLGLPHGFSAEIALQLGPDVTVIDCAADFRLQNAADWEKFYGS
HHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCEEEEEECCCCCCCCCCCHHHHCCC
EHQGTWPYGIPEMPGHREALRGAKRVAVPGCFPTGATLALIPAVQAGLIEPDVSVVSITG
CCCCCCCCCCCCCCCHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEE
VSGGGKKASVALLGSETMGSLKAYNTSGKHRHTPEIAQNLGEVSDKPVKVSFTPVLAPLP
CCCCCCEEEEEEECCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEECCHHHCCC
RGILTTATAPLKEGVTAEQARAVYEEFYAQETFVHVLPEGAQPQTQAVLGSNMCHVQVEI
CCHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHCCCEEEEEEEE
DEEAGKVLVTSAIDNLTKGTAGAAVQCMNLSVGFDEAAGLPQVGVAP
CCCCCCEEEEHHHHHHCCCCCCCEEEEEEEECCCHHHCCCCCCCCCC
>Mature Secondary Structure 
TIKVAIAGASGYAGGEILRLLLGHPAYASGELEIGALTAASTAGSTLGELMPHIPQLAD
EEEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHH
RVIQDTTAETLAGHDVVFLGLPHGFSAEIALQLGPDVTVIDCAADFRLQNAADWEKFYGS
HHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCEEEEEECCCCCCCCCCCHHHHCCC
EHQGTWPYGIPEMPGHREALRGAKRVAVPGCFPTGATLALIPAVQAGLIEPDVSVVSITG
CCCCCCCCCCCCCCCHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEE
VSGGGKKASVALLGSETMGSLKAYNTSGKHRHTPEIAQNLGEVSDKPVKVSFTPVLAPLP
CCCCCCEEEEEEECCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEECCHHHCCC
RGILTTATAPLKEGVTAEQARAVYEEFYAQETFVHVLPEGAQPQTQAVLGSNMCHVQVEI
CCHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHCCCEEEEEEEE
DEEAGKVLVTSAIDNLTKGTAGAAVQCMNLSVGFDEAAGLPQVGVAP
CCCCCCEEEEHHHHHHCCCCCCCEEEEEEEECCCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA