| Definition | Corynebacterium glutamicum R chromosome, complete genome. |
|---|---|
| Accession | NC_009342 |
| Length | 3,314,179 |
Click here to switch to the map view.
The map label for this gene is yqhE [C]
Identifier: 145295493
GI number: 145295493
Start: 1562685
End: 1563560
Strand: Direct
Name: yqhE [C]
Synonym: cgR_1422
Alternate gene names: 145295493
Gene position: 1562685-1563560 (Clockwise)
Preceding gene: 145295492
Following gene: 145295496
Centisome position: 47.15
GC content: 54.11
Gene sequence:
>876_bases ATGACTTTCACACTGAACAACGGACTCGCCATTCCCGACATTGGATTTGGTGTATTCCAAACCCCACCCGATGAAACCCG AAACTCCGTTAACGCTGCTCTTGAAGCCGGCTATCGCCACATCGACACCGCCGCCGCATACGGCAATGAACGTGAAGTCG GTGAAGCAATCGCAGCATCCGGCATTGGCCGCGACGAGATCACCATCGAAACCAAAACCTGGGTGACCGACTACGGCTTC GAGGAAACTCTCCACGCATTCGACAAGGCCACAGGCAAGCTTGGCGTCGATACGCTGGACATTTTGATCTTGCACCAGGC AGTGCCAAGCAGCTTTGATCGCACCATCGCCGCCTACAAAGCGCTAGAGAAGCTGCTTTTCGACGGCGCGGTGCGGGCAA TCGGAGTCAGTAATTTCATGCCAGAGCACCTGGACAAACTCCTTTTGGAAACCTCCATTGTCCCAGCTCTGAACCAAATC GAATGCCACCCCTACTTCCAGCAGCGTGACGTGCTTGCCCGCAATGAGCAGCTTGGCATCTTGACTCAGGCGTGGTCACC AATCGGTGGCATCACCTTCTACCGCGACGGACAGCTTCCAAGCACTCTAGAAAATGAGGTCATCGCTGGAATCGCCGCTG AAGTTGGCAAAACACCAGCTCAGGTCATGCTGCGCTGGCACCTGCAGCGTGGACGTCACGCAATTCCAAAGTCTGTAACC CCATCACGCATTGTGGAAAACTTTGAGATCTTTGATTTCGAACTCTCCGATGAGCAACTACAGCAAATCGATGCCCTCAA CACCGATCTGCGCGGTGGCCCAGAACCAGAGAACATCACCATGGAAAACTACTACCGAGAAATCCCGGAAGCCTAA
Upstream 100 bases:
>100_bases CGGAAGGTTCGACCTCAGCAATGAACCTTCAACTTCTGGCCAATTGGACAGGTAATGACAGCCCCTCCCTCAGCGCAGAA CTTGGTGACACTATTTAATT
Downstream 100 bases:
>100_bases AGGCCATTTAAAGGGTCGGAAATTTCAAGGGTCCTTCCGTCCTATGTTGATGTTTCTGACCCCTTGGAGGCGAATGTAGG CCTATGTATTTTATGCCTAT
Product: hypothetical protein
Products: morphinone; NADH; NADPH; H+
Alternate protein names: NA
Number of amino acids: Translated: 291; Mature: 290
Protein sequence:
>291_residues MTFTLNNGLAIPDIGFGVFQTPPDETRNSVNAALEAGYRHIDTAAAYGNEREVGEAIAASGIGRDEITIETKTWVTDYGF EETLHAFDKATGKLGVDTLDILILHQAVPSSFDRTIAAYKALEKLLFDGAVRAIGVSNFMPEHLDKLLLETSIVPALNQI ECHPYFQQRDVLARNEQLGILTQAWSPIGGITFYRDGQLPSTLENEVIAGIAAEVGKTPAQVMLRWHLQRGRHAIPKSVT PSRIVENFEIFDFELSDEQLQQIDALNTDLRGGPEPENITMENYYREIPEA
Sequences:
>Translated_291_residues MTFTLNNGLAIPDIGFGVFQTPPDETRNSVNAALEAGYRHIDTAAAYGNEREVGEAIAASGIGRDEITIETKTWVTDYGF EETLHAFDKATGKLGVDTLDILILHQAVPSSFDRTIAAYKALEKLLFDGAVRAIGVSNFMPEHLDKLLLETSIVPALNQI ECHPYFQQRDVLARNEQLGILTQAWSPIGGITFYRDGQLPSTLENEVIAGIAAEVGKTPAQVMLRWHLQRGRHAIPKSVT PSRIVENFEIFDFELSDEQLQQIDALNTDLRGGPEPENITMENYYREIPEA >Mature_290_residues TFTLNNGLAIPDIGFGVFQTPPDETRNSVNAALEAGYRHIDTAAAYGNEREVGEAIAASGIGRDEITIETKTWVTDYGFE ETLHAFDKATGKLGVDTLDILILHQAVPSSFDRTIAAYKALEKLLFDGAVRAIGVSNFMPEHLDKLLLETSIVPALNQIE CHPYFQQRDVLARNEQLGILTQAWSPIGGITFYRDGQLPSTLENEVIAGIAAEVGKTPAQVMLRWHLQRGRHAIPKSVTP SRIVENFEIFDFELSDEQLQQIDALNTDLRGGPEPENITMENYYREIPEA
Specific function: Reduction [C]
COG id: COG0656
COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the aldo/keto reductase family [H]
Homologues:
Organism=Homo sapiens, GI24497577, Length=290, Percent_Identity=37.2413793103448, Blast_Score=208, Evalue=6e-54, Organism=Homo sapiens, GI5174391, Length=290, Percent_Identity=37.2413793103448, Blast_Score=208, Evalue=6e-54, Organism=Homo sapiens, GI223468663, Length=304, Percent_Identity=36.1842105263158, Blast_Score=187, Evalue=1e-47, Organism=Homo sapiens, GI4502049, Length=292, Percent_Identity=36.6438356164384, Blast_Score=170, Evalue=1e-42, Organism=Homo sapiens, GI93277124, Length=317, Percent_Identity=31.8611987381703, Blast_Score=164, Evalue=1e-40, Organism=Homo sapiens, GI291291012, Length=274, Percent_Identity=35.4014598540146, Blast_Score=163, Evalue=2e-40, Organism=Homo sapiens, GI5174695, Length=298, Percent_Identity=34.2281879194631, Blast_Score=162, Evalue=4e-40, Organism=Homo sapiens, GI310109922, Length=281, Percent_Identity=33.4519572953737, Blast_Score=160, Evalue=1e-39, Organism=Homo sapiens, GI5453543, Length=298, Percent_Identity=32.2147651006711, Blast_Score=159, Evalue=2e-39, Organism=Homo sapiens, GI310109920, Length=298, Percent_Identity=32.2147651006711, Blast_Score=158, Evalue=6e-39, Organism=Homo sapiens, GI45446745, Length=298, Percent_Identity=32.2147651006711, Blast_Score=158, Evalue=6e-39, Organism=Homo sapiens, GI4503285, Length=298, Percent_Identity=32.2147651006711, Blast_Score=158, Evalue=6e-39, Organism=Homo sapiens, GI24497585, Length=296, Percent_Identity=33.1081081081081, Blast_Score=152, Evalue=3e-37, Organism=Homo sapiens, GI24497583, Length=295, Percent_Identity=32.5423728813559, Blast_Score=148, Evalue=6e-36, Organism=Homo sapiens, GI300116271, Length=277, Percent_Identity=33.5740072202166, Blast_Score=142, Evalue=4e-34, Organism=Homo sapiens, GI300116273, Length=277, Percent_Identity=32.8519855595668, Blast_Score=137, Evalue=2e-32, Organism=Homo sapiens, GI310109924, Length=154, Percent_Identity=36.3636363636364, Blast_Score=102, Evalue=5e-22, Organism=Homo sapiens, GI310109926, Length=127, Percent_Identity=31.496062992126, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI207028673, Length=127, Percent_Identity=31.496062992126, Blast_Score=67, Evalue=1e-11, Organism=Escherichia coli, GI87082198, Length=278, Percent_Identity=40.2877697841727, Blast_Score=214, Evalue=6e-57, Organism=Escherichia coli, GI1786400, Length=270, Percent_Identity=35.9259259259259, Blast_Score=143, Evalue=2e-35, Organism=Escherichia coli, GI1788081, Length=284, Percent_Identity=28.5211267605634, Blast_Score=96, Evalue=3e-21, Organism=Escherichia coli, GI1787674, Length=299, Percent_Identity=26.0869565217391, Blast_Score=68, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17537075, Length=293, Percent_Identity=36.1774744027304, Blast_Score=186, Evalue=1e-47, Organism=Caenorhabditis elegans, GI17537077, Length=293, Percent_Identity=35.8361774744027, Blast_Score=186, Evalue=1e-47, Organism=Caenorhabditis elegans, GI71998625, Length=288, Percent_Identity=34.0277777777778, Blast_Score=171, Evalue=6e-43, Organism=Caenorhabditis elegans, GI17564128, Length=298, Percent_Identity=32.8859060402685, Blast_Score=152, Evalue=3e-37, Organism=Caenorhabditis elegans, GI17561298, Length=277, Percent_Identity=32.8519855595668, Blast_Score=145, Evalue=2e-35, Organism=Caenorhabditis elegans, GI17537079, Length=298, Percent_Identity=29.5302013422819, Blast_Score=144, Evalue=5e-35, Organism=Caenorhabditis elegans, GI17550248, Length=287, Percent_Identity=30.6620209059233, Blast_Score=140, Evalue=9e-34, Organism=Caenorhabditis elegans, GI17538386, Length=281, Percent_Identity=31.6725978647687, Blast_Score=139, Evalue=2e-33, Organism=Caenorhabditis elegans, GI17566692, Length=289, Percent_Identity=30.1038062283737, Blast_Score=131, Evalue=5e-31, Organism=Caenorhabditis elegans, GI17552492, Length=278, Percent_Identity=26.978417266187, Blast_Score=129, Evalue=2e-30, Organism=Caenorhabditis elegans, GI17561300, Length=284, Percent_Identity=29.9295774647887, Blast_Score=119, Evalue=2e-27, Organism=Caenorhabditis elegans, GI17562292, Length=284, Percent_Identity=27.112676056338, Blast_Score=103, Evalue=1e-22, Organism=Saccharomyces cerevisiae, GI6320576, Length=283, Percent_Identity=36.7491166077738, Blast_Score=172, Evalue=6e-44, Organism=Saccharomyces cerevisiae, GI6324694, Length=294, Percent_Identity=34.6938775510204, Blast_Score=164, Evalue=2e-41, Organism=Saccharomyces cerevisiae, GI6322556, Length=271, Percent_Identity=31.7343173431734, Blast_Score=153, Evalue=3e-38, Organism=Saccharomyces cerevisiae, GI6321896, Length=306, Percent_Identity=33.0065359477124, Blast_Score=147, Evalue=2e-36, Organism=Saccharomyces cerevisiae, GI6319625, Length=300, Percent_Identity=31, Blast_Score=132, Evalue=6e-32, Organism=Saccharomyces cerevisiae, GI6320079, Length=281, Percent_Identity=29.8932384341637, Blast_Score=108, Evalue=1e-24, Organism=Drosophila melanogaster, GI24644950, Length=299, Percent_Identity=35.4515050167224, Blast_Score=177, Evalue=6e-45, Organism=Drosophila melanogaster, GI221378297, Length=319, Percent_Identity=33.8557993730408, Blast_Score=171, Evalue=4e-43, Organism=Drosophila melanogaster, GI24663317, Length=296, Percent_Identity=35.1351351351351, Blast_Score=167, Evalue=8e-42, Organism=Drosophila melanogaster, GI45553081, Length=292, Percent_Identity=33.5616438356164, Blast_Score=159, Evalue=2e-39, Organism=Drosophila melanogaster, GI24657054, Length=305, Percent_Identity=33.4426229508197, Blast_Score=159, Evalue=2e-39, Organism=Drosophila melanogaster, GI24662789, Length=294, Percent_Identity=32.9931972789116, Blast_Score=159, Evalue=3e-39, Organism=Drosophila melanogaster, GI20129731, Length=291, Percent_Identity=32.9896907216495, Blast_Score=158, Evalue=3e-39, Organism=Drosophila melanogaster, GI21356425, Length=302, Percent_Identity=32.7814569536424, Blast_Score=156, Evalue=1e-38, Organism=Drosophila melanogaster, GI24662781, Length=275, Percent_Identity=35.2727272727273, Blast_Score=147, Evalue=1e-35, Organism=Drosophila melanogaster, GI24662785, Length=303, Percent_Identity=34.3234323432343, Blast_Score=146, Evalue=1e-35, Organism=Drosophila melanogaster, GI281366140, Length=257, Percent_Identity=33.4630350194552, Blast_Score=136, Evalue=2e-32,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001395 - InterPro: IPR018170 - InterPro: IPR020471 - InterPro: IPR023210 [H]
Pfam domain/function: PF00248 Aldo_ket_red [H]
EC number: 1.1.1.218
Molecular weight: Translated: 32256; Mature: 32124
Theoretical pI: Translated: 4.39; Mature: 4.39
Prosite motif: PS00798 ALDOKETO_REDUCTASE_1 ; PS00062 ALDOKETO_REDUCTASE_2 ; PS00063 ALDOKETO_REDUCTASE_3
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 1.4 %Met (Translated Protein) 1.7 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 1.0 %Met (Mature Protein) 1.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTFTLNNGLAIPDIGFGVFQTPPDETRNSVNAALEAGYRHIDTAAAYGNEREVGEAIAAS CEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC GIGRDEITIETKTWVTDYGFEETLHAFDKATGKLGVDTLDILILHQAVPSSFDRTIAAYK CCCCCEEEEEEEHEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHH ALEKLLFDGAVRAIGVSNFMPEHLDKLLLETSIVPALNQIECHPYFQQRDVLARNEQLGI HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHCCCCCEE LTQAWSPIGGITFYRDGQLPSTLENEVIAGIAAEVGKTPAQVMLRWHLQRGRHAIPKSVT HHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCC PSRIVENFEIFDFELSDEQLQQIDALNTDLRGGPEPENITMENYYREIPEA HHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCC >Mature Secondary Structure TFTLNNGLAIPDIGFGVFQTPPDETRNSVNAALEAGYRHIDTAAAYGNEREVGEAIAAS EEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC GIGRDEITIETKTWVTDYGFEETLHAFDKATGKLGVDTLDILILHQAVPSSFDRTIAAYK CCCCCEEEEEEEHEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHH ALEKLLFDGAVRAIGVSNFMPEHLDKLLLETSIVPALNQIECHPYFQQRDVLARNEQLGI HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHCCCCCEE LTQAWSPIGGITFYRDGQLPSTLENEVIAGIAAEVGKTPAQVMLRWHLQRGRHAIPKSVT HHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCC PSRIVENFEIFDFELSDEQLQQIDALNTDLRGGPEPENITMENYYREIPEA HHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: morphine; NAD+; NADP+
Specific reaction: morphine + NAD(P)+ = morphinone + NAD(P)H + H+
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA