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The map label for this gene is coaD

Identifier: 145295470

GI number: 145295470

Start: 1537432

End: 1537914

Strand: Direct

Name: coaD

Synonym: cgR_1403

Alternate gene names: 145295470

Gene position: 1537432-1537914 (Clockwise)

Preceding gene: 145295469

Following gene: 145295474

Centisome position: 46.39

GC content: 56.52

Gene sequence:

>483_bases
ATGAAAGCCGTTTGCCCAGGATCATTCGACCCCATCACCCTCGGCCATCTCGACATCGTGACCCGCGCCGCCGCGCAATT
TAGCGAAGTCACCATCTTGGTCACCGCCAACCCCAACAAAAACTCAGGACTGTTCACCGTCGCAGAACGCATGGACCTCA
TCCGCGAATCCACCGCACACCTCGACAACGTAAAAGTAGACACCTGGGCCTCACTGCTCGTGGATTACACCACCGAACAT
GGCATCGGCGCTCTAGTCAAGGGCCTGCGAAGCTCCCTCGATTACGAATACGAGCTTCCCATGGCACAGATGAACAGGCG
ACTCACCGGCGTAGACACCTTCTTCCTCCTCACCGACGAGAAATACGGCTACGTCAGCTCCACACTGTGCAAAGAAGTAG
CCCGCTTCGGTGGCGATGTCTCCGGCCTCCTACCTGAGGTAGTGGCAAAAGCCGTGACAGAAAAATACAGCAACCAGCAC
TAG

Upstream 100 bases:

>100_bases
CTGGCTGGTACCCACCACCCAGAAACTTAAAAAACGAACCTACGGCATAGCACGCATGGACATGGCCGTTTTCGACGAAT
CTCTGCTTCAGGAGTAACCA

Downstream 100 bases:

>100_bases
TTTCTTTTGCATCAAGCGTCTAGACTATGGAACCGACTTATCACAGACACGTGAAATAAGGAGGTGACAGCGATGGGTGT
GGACCGACGGATGTGGAAAA

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MKAVCPGSFDPITLGHLDIVTRAAAQFSEVTILVTANPNKNSGLFTVAERMDLIRESTAHLDNVKVDTWASLLVDYTTEH
GIGALVKGLRSSLDYEYELPMAQMNRRLTGVDTFFLLTDEKYGYVSSTLCKEVARFGGDVSGLLPEVVAKAVTEKYSNQH

Sequences:

>Translated_160_residues
MKAVCPGSFDPITLGHLDIVTRAAAQFSEVTILVTANPNKNSGLFTVAERMDLIRESTAHLDNVKVDTWASLLVDYTTEH
GIGALVKGLRSSLDYEYELPMAQMNRRLTGVDTFFLLTDEKYGYVSSTLCKEVARFGGDVSGLLPEVVAKAVTEKYSNQH
>Mature_160_residues
MKAVCPGSFDPITLGHLDIVTRAAAQFSEVTILVTANPNKNSGLFTVAERMDLIRESTAHLDNVKVDTWASLLVDYTTEH
GIGALVKGLRSSLDYEYELPMAQMNRRLTGVDTFFLLTDEKYGYVSSTLCKEVARFGGDVSGLLPEVVAKAVTEKYSNQH

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=157, Percent_Identity=42.0382165605096, Blast_Score=140, Evalue=6e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_CORGB (A4QDU2)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001138291.1
- ProteinModelPortal:   A4QDU2
- SMR:   A4QDU2
- STRING:   A4QDU2
- GeneID:   4993839
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_1403
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 17575; Mature: 17575

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVCPGSFDPITLGHLDIVTRAAAQFSEVTILVTANPNKNSGLFTVAERMDLIRESTAH
CCCCCCCCCCCEEEHHHHHHHHHHHHHCEEEEEEEECCCCCCCEEHHHHHHHHHHHHHHH
LDNVKVDTWASLLVDYTTEHGIGALVKGLRSSLDYEYELPMAQMNRRLTGVDTFFLLTDE
HCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEECCHHHHCCCCCCCEEEEEEECC
KYGYVSSTLCKEVARFGGDVSGLLPEVVAKAVTEKYSNQH
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKAVCPGSFDPITLGHLDIVTRAAAQFSEVTILVTANPNKNSGLFTVAERMDLIRESTAH
CCCCCCCCCCCEEEHHHHHHHHHHHHHCEEEEEEEECCCCCCCEEHHHHHHHHHHHHHHH
LDNVKVDTWASLLVDYTTEHGIGALVKGLRSSLDYEYELPMAQMNRRLTGVDTFFLLTDE
HCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEECCHHHHCCCCCCCEEEEEEECC
KYGYVSSTLCKEVARFGGDVSGLLPEVVAKAVTEKYSNQH
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA