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The map label for this gene is gpsA

Identifier: 145295461

GI number: 145295461

Start: 1527820

End: 1528818

Strand: Direct

Name: gpsA

Synonym: cgR_1394

Alternate gene names: 145295461

Gene position: 1527820-1528818 (Clockwise)

Preceding gene: 145295460

Following gene: 145295462

Centisome position: 46.1

GC content: 57.36

Gene sequence:

>999_bases
GTGGTTTCTGTAAGCGTGATGGGTGCAGGTTCCTGGGGAACCACGTTGGCCAAGGTCTTCTCTGATGCTGGCAACGCTGT
GACGTTGTGGGCGAGGCGGGAAGAGTTGGCAAGCACCATCCGTGACAGCCATGAAAACCGTGATTACCTTCCGGGGATTA
CGTTGCCGGAGTCGCTGCAGGTCACATCATCGGCAACGGAGGCTTTAGAGGGCGCAGCCATTGTGGTGTTGGCGATTCCT
TCGCAGGCGTTGCGTGGCAACTTGGCGGAGTGGAAAGAGACGATCCCGCAGGATGCGACCTTGGTGTCCTTGGCTAAAGG
TATTGAAAAGGGCACGCACCTGCGGATGAGTGAAGTGATCGCGGAGGTGACGGAAGCGGATCCTTCACGCATCGCGGTGT
TGTCGGGGCCAAACCTTGCTCGTGAGATCGCGGAGGGGCAGCCTGCAGCTACGGTGATTGCTTGCCCTGATGAAAACCGA
GCGAAACTTGTGCAGGCTGCAGTGGCTGCGCCGTATTTCCGCCCGTACACCAACACTGATGTGGTGGGCACTGAAATCGG
TGGTGCGTGTAAGAACGTCATCGCGCTGGCCTGTGGTATTTCCCATGGTTACGGCCTGGGGGAGAACACCAATGCATCGC
TGATTACTCGTGGCCTTGCAGAGATCGCACGCCTCGGTGCCACATTGGGTGCGGATGCGAAGACTTTTTCTGGCCTTGCG
GGAATGGGCGACTTGGTGGCTACGTGTTCATCACCGCTGTCGCGTAACCGCAGCTTCGGTGAGCGTTTGGGTCAGGGTGA
ATCCCTAGAGAAGGCTCGCGAGGCAACCAATGGTCAGGTCGCGGAGGGTGTTATTTCCTCGCAGTCGATTTTTGATCTTG
CCACCAAGCTTGGCGTGGAGATGCCAATCACCCAGGCTGTCTACGGTGTCTGCCACCGGGATATGAAAGTAACTGACATG
ATTGTGGCTCTCATGGGCAGGTCTAAGAAGGCTGAGTAG

Upstream 100 bases:

>100_bases
GGGCAGCAGCGGCAGGTTTCCAGGAGGTTTCCATGCGGGTGGCTTGGGACATGGGCTAACCTGAGACGGTTGAATATCGT
TTTCGAAAGGTGGGTTTCGC

Downstream 100 bases:

>100_bases
TCTTAGGTTGTAAGCTTCAATGCTGTGAGCAACTCTAATTCCGGAAAAGTCCGCGTCGCAGTCGTTTATGGTGGTCGCAG
TTCTGAGCACTCCGTCTCCT

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MVSVSVMGAGSWGTTLAKVFSDAGNAVTLWARREELASTIRDSHENRDYLPGITLPESLQVTSSATEALEGAAIVVLAIP
SQALRGNLAEWKETIPQDATLVSLAKGIEKGTHLRMSEVIAEVTEADPSRIAVLSGPNLAREIAEGQPAATVIACPDENR
AKLVQAAVAAPYFRPYTNTDVVGTEIGGACKNVIALACGISHGYGLGENTNASLITRGLAEIARLGATLGADAKTFSGLA
GMGDLVATCSSPLSRNRSFGERLGQGESLEKAREATNGQVAEGVISSQSIFDLATKLGVEMPITQAVYGVCHRDMKVTDM
IVALMGRSKKAE

Sequences:

>Translated_332_residues
MVSVSVMGAGSWGTTLAKVFSDAGNAVTLWARREELASTIRDSHENRDYLPGITLPESLQVTSSATEALEGAAIVVLAIP
SQALRGNLAEWKETIPQDATLVSLAKGIEKGTHLRMSEVIAEVTEADPSRIAVLSGPNLAREIAEGQPAATVIACPDENR
AKLVQAAVAAPYFRPYTNTDVVGTEIGGACKNVIALACGISHGYGLGENTNASLITRGLAEIARLGATLGADAKTFSGLA
GMGDLVATCSSPLSRNRSFGERLGQGESLEKAREATNGQVAEGVISSQSIFDLATKLGVEMPITQAVYGVCHRDMKVTDM
IVALMGRSKKAE
>Mature_332_residues
MVSVSVMGAGSWGTTLAKVFSDAGNAVTLWARREELASTIRDSHENRDYLPGITLPESLQVTSSATEALEGAAIVVLAIP
SQALRGNLAEWKETIPQDATLVSLAKGIEKGTHLRMSEVIAEVTEADPSRIAVLSGPNLAREIAEGQPAATVIACPDENR
AKLVQAAVAAPYFRPYTNTDVVGTEIGGACKNVIALACGISHGYGLGENTNASLITRGLAEIARLGATLGADAKTFSGLA
GMGDLVATCSSPLSRNRSFGERLGQGESLEKAREATNGQVAEGVISSQSIFDLATKLGVEMPITQAVYGVCHRDMKVTDM
IVALMGRSKKAE

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=345, Percent_Identity=32.1739130434783, Blast_Score=158, Evalue=8e-39,
Organism=Homo sapiens, GI24307999, Length=344, Percent_Identity=30.2325581395349, Blast_Score=149, Evalue=5e-36,
Organism=Escherichia coli, GI1790037, Length=331, Percent_Identity=40.785498489426, Blast_Score=239, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI32564399, Length=344, Percent_Identity=30.8139534883721, Blast_Score=154, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI193210136, Length=354, Percent_Identity=30.225988700565, Blast_Score=151, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI32564403, Length=353, Percent_Identity=30.3116147308782, Blast_Score=151, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI17507425, Length=332, Percent_Identity=27.4096385542169, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI193210134, Length=342, Percent_Identity=27.1929824561404, Blast_Score=113, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6324513, Length=351, Percent_Identity=31.3390313390313, Blast_Score=154, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6320181, Length=358, Percent_Identity=31.2849162011173, Blast_Score=150, Evalue=3e-37,
Organism=Drosophila melanogaster, GI17136200, Length=338, Percent_Identity=29.585798816568, Blast_Score=143, Evalue=1e-34,
Organism=Drosophila melanogaster, GI17136204, Length=338, Percent_Identity=29.585798816568, Blast_Score=143, Evalue=1e-34,
Organism=Drosophila melanogaster, GI17136202, Length=338, Percent_Identity=29.585798816568, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI22026922, Length=345, Percent_Identity=26.6666666666667, Blast_Score=118, Evalue=4e-27,
Organism=Drosophila melanogaster, GI45551945, Length=340, Percent_Identity=27.3529411764706, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI281362270, Length=284, Percent_Identity=28.169014084507, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24648969, Length=299, Percent_Identity=27.7591973244147, Blast_Score=95, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_CORGB (A4QDT3)

Other databases:

- EMBL:   AP009044
- RefSeq:   YP_001138282.1
- ProteinModelPortal:   A4QDT3
- SMR:   A4QDT3
- STRING:   A4QDT3
- GeneID:   4993363
- GenomeReviews:   AP009044_GR
- KEGG:   cgt:cgR_1394
- eggNOG:   COG0240
- HOGENOM:   HBG586392
- OMA:   SQTLRGN
- ProtClustDB:   PRK00094
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 34683; Mature: 34683

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 191-191 BINDING 106-106 BINDING 106-106 BINDING 140-140 BINDING 255-255 BINDING 282-282

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSVSVMGAGSWGTTLAKVFSDAGNAVTLWARREELASTIRDSHENRDYLPGITLPESLQ
CEEEEEEECCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
VTSSATEALEGAAIVVLAIPSQALRGNLAEWKETIPQDATLVSLAKGIEKGTHLRMSEVI
HHHHHHHHHCCCEEEEEECCCHHHHCCHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHH
AEVTEADPSRIAVLSGPNLAREIAEGQPAATVIACPDENRAKLVQAAVAAPYFRPYTNTD
HHHHHCCCCEEEEECCCHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCC
VVGTEIGGACKNVIALACGISHGYGLGENTNASLITRGLAEIARLGATLGADAKTFSGLA
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHC
GMGDLVATCSSPLSRNRSFGERLGQGESLEKAREATNGQVAEGVISSQSIFDLATKLGVE
CHHHHHHHHCCHHHCCHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
MPITQAVYGVCHRDMKVTDMIVALMGRSKKAE
CCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVSVSVMGAGSWGTTLAKVFSDAGNAVTLWARREELASTIRDSHENRDYLPGITLPESLQ
CEEEEEEECCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
VTSSATEALEGAAIVVLAIPSQALRGNLAEWKETIPQDATLVSLAKGIEKGTHLRMSEVI
HHHHHHHHHCCCEEEEEECCCHHHHCCHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHH
AEVTEADPSRIAVLSGPNLAREIAEGQPAATVIACPDENRAKLVQAAVAAPYFRPYTNTD
HHHHHCCCCEEEEECCCHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCC
VVGTEIGGACKNVIALACGISHGYGLGENTNASLITRGLAEIARLGATLGADAKTFSGLA
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHC
GMGDLVATCSSPLSRNRSFGERLGQGESLEKAREATNGQVAEGVISSQSIFDLATKLGVE
CHHHHHHHHCCHHHCCHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
MPITQAVYGVCHRDMKVTDMIVALMGRSKKAE
CCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA