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The map label for this gene is yrkH [H]

Identifier: 145295451

GI number: 145295451

Start: 1519834

End: 1521243

Strand: Reverse

Name: yrkH [H]

Synonym: cgR_1385

Alternate gene names: 145295451

Gene position: 1521243-1519834 (Counterclockwise)

Preceding gene: 145295452

Following gene: 145295449

Centisome position: 45.9

GC content: 53.9

Gene sequence:

>1410_bases
ATGCTTTTTGAACGCATCTACGAAGAAGGCCTCGCCCAAGCCAGCTATTTCATTGGCTGCCAACGCGAAGGCAAAGCGAT
TGTTGTTGATGCTCGCCGAGATATCCAGACCTATCTGGACCTTGCAGCAAAAAACAACATGGTCATTAGCGCCGTAACCG
AAACCCATATTCATGCCGATTATCTCTCCGGTACTCGCGAACTTGCAGCTGCCACCGGCGCCGAGATTTTCCTCTCTGGC
GAAGGCGGAGCTGATTGGCAATATGGCTTTACAGGCACCACCTTGATGCACAATTCCACCATCAAGCTGGGAAATATCAC
CATAACAGCCAAGCACACTCCCGGACACACTCCAGAGCACCTGTCATTTTTGATTACTGATGGTGCGGTCTCAAAGGATC
CCGGTTTTATGCTCAGCGGTGACTTCGTCTTCGTAGGTGACGTGGGACGTCCAGATTTGCTTGATGAGGCAGCTGGCGGC
GTGGACACCCGCTTCGCCGGAGCACAGCAACTCTTCCATAGCCTAAAAGAGCAGTTCCTTACACTCCCCGACCACATTCA
GGTTTATCCAGGTCATGGTGCTGGCAGCCCTTGTGGCAAGGCATTGGGCGCGATCCCTAGCACCACCGTGGGATATGAAA
AGGCTAATGCGTGGTGGGCTCCATATCTGCGCAGTGATGATGAAGCCGGCTTTGTGGAAGAGCTTCTCGACGGCCAGCCA
GATGCCCACGCTTACTTTGCTCGCATGAAAAAGCAGAACAAGCAGGGACCTGCAGTACTTGGTACATTATCCCCGCTTGT
GAAGCTAGAAGCCGAGGAAGTCGTCGAAAAGCTTGGTTCTGAAGCAGTGTTTGTGGACACCCGCGAGCAAAACCAAGTCC
ATCTCGGAACCGTTGTTGGGGCATTGAATATTCCGCGCGGCGCCAAGGCGTCCAATTTTGCGGCATGGGTTATTGATCCT
CAAAAGGATGCTCAAGACCTTATTGTTTTGGCTCCGGACGCCAATACCGCTGCGGATTTCCGCGACGCTTTGCTGCGGGT
TGGCATCGACACTGTGCGTTATTTCACCAACAGTATCGATGGTTTGCCTACCTTTGTGCCAGAACTCATCTCCCCCGCTG
AGCTAGCTGAGACCAACTATGACGCACTGATTGATATCCGTGCAAAGTCCGAATTTGCCGCTGGCAGCGTTCCCGGCGCA
CAGCAACTTTCTGGAGGTTCGGCCATGTGGCGCCTCAATGAGCTGCCTGCGGGTGGCACTTTGGTAACCTTCTGCCAATC
AGGAGCGCGAAATACCGTGGTAGCCAATGCTTTGCGACGCGCCGGGTTCACCGTTATCGAGCTCGAGGGCAGCTACGCCG
CGTGGGAAAAATCAGCTGCCAACCCTAAAAACTTGCAGACTGCCGTCTAG

Upstream 100 bases:

>100_bases
AAATATACCCCCCGGGGTATCTTGACAGATTAAAGCTCGATGTTTTAGGCTCTACATATACCCCCAAGGGTATCCCCTCA
ACTTTGATCTAAGGTGTCAC

Downstream 100 bases:

>100_bases
TTTTAGATCCGGCGCTGTATCAACTAAACAATCACCGCTTTTAAGAGAGGCCACATTATGTGTCGTGCAGTTACTTGTAA
GAAGTGCGGAAAGACCACCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MLFERIYEEGLAQASYFIGCQREGKAIVVDARRDIQTYLDLAAKNNMVISAVTETHIHADYLSGTRELAAATGAEIFLSG
EGGADWQYGFTGTTLMHNSTIKLGNITITAKHTPGHTPEHLSFLITDGAVSKDPGFMLSGDFVFVGDVGRPDLLDEAAGG
VDTRFAGAQQLFHSLKEQFLTLPDHIQVYPGHGAGSPCGKALGAIPSTTVGYEKANAWWAPYLRSDDEAGFVEELLDGQP
DAHAYFARMKKQNKQGPAVLGTLSPLVKLEAEEVVEKLGSEAVFVDTREQNQVHLGTVVGALNIPRGAKASNFAAWVIDP
QKDAQDLIVLAPDANTAADFRDALLRVGIDTVRYFTNSIDGLPTFVPELISPAELAETNYDALIDIRAKSEFAAGSVPGA
QQLSGGSAMWRLNELPAGGTLVTFCQSGARNTVVANALRRAGFTVIELEGSYAAWEKSAANPKNLQTAV

Sequences:

>Translated_469_residues
MLFERIYEEGLAQASYFIGCQREGKAIVVDARRDIQTYLDLAAKNNMVISAVTETHIHADYLSGTRELAAATGAEIFLSG
EGGADWQYGFTGTTLMHNSTIKLGNITITAKHTPGHTPEHLSFLITDGAVSKDPGFMLSGDFVFVGDVGRPDLLDEAAGG
VDTRFAGAQQLFHSLKEQFLTLPDHIQVYPGHGAGSPCGKALGAIPSTTVGYEKANAWWAPYLRSDDEAGFVEELLDGQP
DAHAYFARMKKQNKQGPAVLGTLSPLVKLEAEEVVEKLGSEAVFVDTREQNQVHLGTVVGALNIPRGAKASNFAAWVIDP
QKDAQDLIVLAPDANTAADFRDALLRVGIDTVRYFTNSIDGLPTFVPELISPAELAETNYDALIDIRAKSEFAAGSVPGA
QQLSGGSAMWRLNELPAGGTLVTFCQSGARNTVVANALRRAGFTVIELEGSYAAWEKSAANPKNLQTAV
>Mature_469_residues
MLFERIYEEGLAQASYFIGCQREGKAIVVDARRDIQTYLDLAAKNNMVISAVTETHIHADYLSGTRELAAATGAEIFLSG
EGGADWQYGFTGTTLMHNSTIKLGNITITAKHTPGHTPEHLSFLITDGAVSKDPGFMLSGDFVFVGDVGRPDLLDEAAGG
VDTRFAGAQQLFHSLKEQFLTLPDHIQVYPGHGAGSPCGKALGAIPSTTVGYEKANAWWAPYLRSDDEAGFVEELLDGQP
DAHAYFARMKKQNKQGPAVLGTLSPLVKLEAEEVVEKLGSEAVFVDTREQNQVHLGTVVGALNIPRGAKASNFAAWVIDP
QKDAQDLIVLAPDANTAADFRDALLRVGIDTVRYFTNSIDGLPTFVPELISPAELAETNYDALIDIRAKSEFAAGSVPGA
QQLSGGSAMWRLNELPAGGTLVTFCQSGARNTVVANALRRAGFTVIELEGSYAAWEKSAANPKNLQTAV

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=198, Percent_Identity=25.7575757575758, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1787158, Length=242, Percent_Identity=25.2066115702479, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17538952, Length=199, Percent_Identity=29.1457286432161, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI221330176, Length=197, Percent_Identity=25.3807106598985, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR001763 [H]

Pfam domain/function: PF00753 Lactamase_B; PF00581 Rhodanese [H]

EC number: NA

Molecular weight: Translated: 50213; Mature: 50213

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFERIYEEGLAQASYFIGCQREGKAIVVDARRDIQTYLDLAAKNNMVISAVTETHIHAD
CCHHHHHHHHHHHHHEEEEECCCCCEEEEECHHHHHHHHHHHCCCCEEEEEEEHHHEEHH
YLSGTRELAAATGAEIFLSGEGGADWQYGFTGTTLMHNSTIKLGNITITAKHTPGHTPEH
HHCCHHHHHHCCCCEEEEECCCCCCEECCCCCEEEEECCEEEEEEEEEEEECCCCCCCCC
LSFLITDGAVSKDPGFMLSGDFVFVGDVGRPDLLDEAAGGVDTRFAGAQQLFHSLKEQFL
EEEEEECCCCCCCCCEEEECCEEEEECCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHC
TLPDHIQVYPGHGAGSPCGKALGAIPSTTVGYEKANAWWAPYLRSDDEAGFVEELLDGQP
CCCCCEEEECCCCCCCHHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCCCHHHHHHCCCC
DAHAYFARMKKQNKQGPAVLGTLSPLVKLEAEEVVEKLGSEAVFVDTREQNQVHLGTVVG
CHHHHHHHHHHCCCCCCEEEECHHHHHHCCHHHHHHHHCCCEEEEECCCCCCEEEEEEEE
ALNIPRGAKASNFAAWVIDPQKDAQDLIVLAPDANTAADFRDALLRVGIDTVRYFTNSID
EEECCCCCCCCCEEEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
GLPTFVPELISPAELAETNYDALIDIRAKSEFAAGSVPGAQQLSGGSAMWRLNELPAGGT
CCHHHHHHHCCCHHHHCCCCCEEEEEEECCCCCCCCCCCHHHCCCCCEEEEEECCCCCCC
LVTFCQSGARNTVVANALRRAGFTVIELEGSYAAWEKSAANPKNLQTAV
EEEEECCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MLFERIYEEGLAQASYFIGCQREGKAIVVDARRDIQTYLDLAAKNNMVISAVTETHIHAD
CCHHHHHHHHHHHHHEEEEECCCCCEEEEECHHHHHHHHHHHCCCCEEEEEEEHHHEEHH
YLSGTRELAAATGAEIFLSGEGGADWQYGFTGTTLMHNSTIKLGNITITAKHTPGHTPEH
HHCCHHHHHHCCCCEEEEECCCCCCEECCCCCEEEEECCEEEEEEEEEEEECCCCCCCCC
LSFLITDGAVSKDPGFMLSGDFVFVGDVGRPDLLDEAAGGVDTRFAGAQQLFHSLKEQFL
EEEEEECCCCCCCCCEEEECCEEEEECCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHC
TLPDHIQVYPGHGAGSPCGKALGAIPSTTVGYEKANAWWAPYLRSDDEAGFVEELLDGQP
CCCCCEEEECCCCCCCHHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCCCHHHHHHCCCC
DAHAYFARMKKQNKQGPAVLGTLSPLVKLEAEEVVEKLGSEAVFVDTREQNQVHLGTVVG
CHHHHHHHHHHCCCCCCEEEECHHHHHHCCHHHHHHHHCCCEEEEECCCCCCEEEEEEEE
ALNIPRGAKASNFAAWVIDPQKDAQDLIVLAPDANTAADFRDALLRVGIDTVRYFTNSID
EEECCCCCCCCCEEEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
GLPTFVPELISPAELAETNYDALIDIRAKSEFAAGSVPGAQQLSGGSAMWRLNELPAGGT
CCHHHHHHHCCCHHHHCCCCCEEEEEEECCCCCCCCCCCHHHCCCCCEEEEEECCCCCCC
LVTFCQSGARNTVVANALRRAGFTVIELEGSYAAWEKSAANPKNLQTAV
EEEEECCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]