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The map label for this gene is malP [H]

Identifier: 145295449

GI number: 145295449

Start: 1517599

End: 1519464

Strand: Reverse

Name: malP [H]

Synonym: cgR_1383

Alternate gene names: 145295449

Gene position: 1519464-1517599 (Counterclockwise)

Preceding gene: 145295451

Following gene: 145295448

Centisome position: 45.85

GC content: 54.93

Gene sequence:

>1866_bases
TTGGGCTACATTTTCGGGCATTTTCCTTTAGACTCATCTGCTATGACTGAAAATCAGCCACTCCCCGCCGACCTCGTCGG
CAGCCATGTTCGTGCCGCTGCTGGCACCCCCGCCGACCTCGCTACTGATCGCAAGTTCTGGACTGGTCTTTCCCGTGCAG
TCCAGGAGCGCATTGCCGATGATTGGGAGCGCACCCGCGAAGCTTATGGTGCTGCTCGCCAGCAACATTATTTCTCCGCT
GAATTCCTCATGGGCCGTGCACTGCTGAACAACCTGACCAACTTAGGTCTGGTTGATGAGGCTGCAGCTACTACCCGTGA
GCTGGGCCATGAGCTCACCGACATCCTGGAAATCGAAAATGACGCAGCACTGGGCAATGGTGGCTTGGGCCGCCTCGCCG
CTTGCTTCCTGGATTCTGCTGTTACCCAGGACTACCCCGTTACTGGTTATGGTCTGCTCTACCGCTTCGGTCTTTTCCGT
CAGTCCTTTAACGAGGGCTTCCAGGTAGAAAAGCCAGACCCATGGCGCGAAGAGGAATATCCTTTTACCATTCGTCGTGC
ATCCGACCAGTTGGTTGTGTGCTTTGACGATATGAAAACTCGCGCTATTCCTTATGACATGCCGATCACCGGCTATGGCA
CTCACAACGTGGGAACTCTGCGCCTGTGGAAGGCGGAGCCGTGGGAAGAATTCGATTACGATGCCTTCAACTCCCAGCGC
TTTACCGACGCCATCATCGAGCGCGAGCGCGTTTCCGATATCTGCCGTGTGCTCTACCCTAATGACACCACCTACGAGGG
CAAGAAGCTGCGCGTTCGCCAGCAGTACTTCTTCACCTCTGCTTCCCTGCAGGCCATGATTCAGGGCCACCTGGCGCACC
ACAAGGACCTCAGCAACTTTGCCGAGTTCCACTCCGTGCAGCTCAATGACACTCACCCAGTGTTGGCTATCCCTGAGCTT
ATGCGTCTGCTCATGGACGAGCATGACATGGGCTGGGAAGAATCCTGGGCAATCGTATCCAAGACCTTCGCATACACTAA
CCACACCGTGCTCACCGAAGCTCTTGAGCAGTGGGATCAGCAGATCTTCCAGCAGCTGTTCTGGCGCGTGTGGGAAATCA
TCACAGAGATCGATCGCCGCTTCCGTTTGGAGCGCGCAGCCGATGGACTGGATGAAGAGACCATCAACCGCATGGCTCCA
ATCCAGCACGGCACTGTTCATATGGCATGGATTGCCTGTTACGCGGCATATTCCATCAATGGCGTGGCAGCGCTGCACAC
CGAGATCATCAAGGCTGAAACCCTGGCTGATTGGTATGCCCTGTGGCCAGAGAAGTTCAACAACAAGACCAACGGTGTTA
CCCCACGCCGTTGGCTGCGCATGATCAACCCAGGTCTGTCTGAACTGCTCACTCGACTTTCCGGTTCCGACGATTGGGTA
ACCGATCTGGATGAGCTGAAGAAGCTGCGCTCCTATGCCGACGATAAGTCCGTGCTTGAAGAACTCCGCGCTATCAAGGC
TGCTAATAAGCAAGACTTCGCCGAGTGGATCCTCGAGCGCCAGGGCATTGAGATTGATCCAGAATCCATCTTTGACGTGC
AGATCAAGCGCCTCCACGAGTACAAGCGCCAGCTCATGAACGCGCTTTACGTACTAGACCTTTACTTCCGCATTAAGGAA
GATGGCCTTACTGATATCCCAGCACGCACTGTCATCTTTGGCGCCAAGGCCGCGCCGGGTTATGTCCGCGCCAAGGCGAT
TATCAAGCTCATCAACTCTATTGCTGACTTGGTAAACAACGATCCTGAGGTTTCCCCGCTGCTCAAGGTTGGTTTTTGTA
GAGAACTACAATGTCTCCCCTGCTGA

Upstream 100 bases:

>100_bases
CGCAAACCCACCGCCGCAGGCAAGAGTTTTTCGTCGAAAAGCGCAGTGTTTTTAGCAATCGGAAGCAATTAACGAATTTA
ATAGTCCCAGTTATGCCCGA

Downstream 100 bases:

>100_bases
GCATATCTTGCCTGCGTCTGATGTCTCCGAGCAGATTTCCACCGCCGGCAAGGAAGCCAGCGGTACCTCCAACATGAAGT
TCATGATGAACGGCGCCCTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 621; Mature: 620

Protein sequence:

>621_residues
MGYIFGHFPLDSSAMTENQPLPADLVGSHVRAAAGTPADLATDRKFWTGLSRAVQERIADDWERTREAYGAARQQHYFSA
EFLMGRALLNNLTNLGLVDEAAATTRELGHELTDILEIENDAALGNGGLGRLAACFLDSAVTQDYPVTGYGLLYRFGLFR
QSFNEGFQVEKPDPWREEEYPFTIRRASDQLVVCFDDMKTRAIPYDMPITGYGTHNVGTLRLWKAEPWEEFDYDAFNSQR
FTDAIIERERVSDICRVLYPNDTTYEGKKLRVRQQYFFTSASLQAMIQGHLAHHKDLSNFAEFHSVQLNDTHPVLAIPEL
MRLLMDEHDMGWEESWAIVSKTFAYTNHTVLTEALEQWDQQIFQQLFWRVWEIITEIDRRFRLERAADGLDEETINRMAP
IQHGTVHMAWIACYAAYSINGVAALHTEIIKAETLADWYALWPEKFNNKTNGVTPRRWLRMINPGLSELLTRLSGSDDWV
TDLDELKKLRSYADDKSVLEELRAIKAANKQDFAEWILERQGIEIDPESIFDVQIKRLHEYKRQLMNALYVLDLYFRIKE
DGLTDIPARTVIFGAKAAPGYVRAKAIIKLINSIADLVNNDPEVSPLLKVGFCRELQCLPC

Sequences:

>Translated_621_residues
MGYIFGHFPLDSSAMTENQPLPADLVGSHVRAAAGTPADLATDRKFWTGLSRAVQERIADDWERTREAYGAARQQHYFSA
EFLMGRALLNNLTNLGLVDEAAATTRELGHELTDILEIENDAALGNGGLGRLAACFLDSAVTQDYPVTGYGLLYRFGLFR
QSFNEGFQVEKPDPWREEEYPFTIRRASDQLVVCFDDMKTRAIPYDMPITGYGTHNVGTLRLWKAEPWEEFDYDAFNSQR
FTDAIIERERVSDICRVLYPNDTTYEGKKLRVRQQYFFTSASLQAMIQGHLAHHKDLSNFAEFHSVQLNDTHPVLAIPEL
MRLLMDEHDMGWEESWAIVSKTFAYTNHTVLTEALEQWDQQIFQQLFWRVWEIITEIDRRFRLERAADGLDEETINRMAP
IQHGTVHMAWIACYAAYSINGVAALHTEIIKAETLADWYALWPEKFNNKTNGVTPRRWLRMINPGLSELLTRLSGSDDWV
TDLDELKKLRSYADDKSVLEELRAIKAANKQDFAEWILERQGIEIDPESIFDVQIKRLHEYKRQLMNALYVLDLYFRIKE
DGLTDIPARTVIFGAKAAPGYVRAKAIIKLINSIADLVNNDPEVSPLLKVGFCRELQCLPC
>Mature_620_residues
GYIFGHFPLDSSAMTENQPLPADLVGSHVRAAAGTPADLATDRKFWTGLSRAVQERIADDWERTREAYGAARQQHYFSAE
FLMGRALLNNLTNLGLVDEAAATTRELGHELTDILEIENDAALGNGGLGRLAACFLDSAVTQDYPVTGYGLLYRFGLFRQ
SFNEGFQVEKPDPWREEEYPFTIRRASDQLVVCFDDMKTRAIPYDMPITGYGTHNVGTLRLWKAEPWEEFDYDAFNSQRF
TDAIIERERVSDICRVLYPNDTTYEGKKLRVRQQYFFTSASLQAMIQGHLAHHKDLSNFAEFHSVQLNDTHPVLAIPELM
RLLMDEHDMGWEESWAIVSKTFAYTNHTVLTEALEQWDQQIFQQLFWRVWEIITEIDRRFRLERAADGLDEETINRMAPI
QHGTVHMAWIACYAAYSINGVAALHTEIIKAETLADWYALWPEKFNNKTNGVTPRRWLRMINPGLSELLTRLSGSDDWVT
DLDELKKLRSYADDKSVLEELRAIKAANKQDFAEWILERQGIEIDPESIFDVQIKRLHEYKRQLMNALYVLDLYFRIKED
GLTDIPARTVIFGAKAAPGYVRAKAIIKLINSIADLVNNDPEVSPLLKVGFCRELQCLPC

Specific function: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties [

COG id: COG0058

COG function: function code G; Glucan phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycogen phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI5032009, Length=603, Percent_Identity=41.4593698175788, Blast_Score=444, Evalue=1e-124,
Organism=Homo sapiens, GI71037379, Length=603, Percent_Identity=42.4543946932007, Blast_Score=442, Evalue=1e-124,
Organism=Homo sapiens, GI21361370, Length=603, Percent_Identity=41.9568822553897, Blast_Score=432, Evalue=1e-121,
Organism=Homo sapiens, GI255653002, Length=601, Percent_Identity=40.9317803660566, Blast_Score=409, Evalue=1e-114,
Organism=Homo sapiens, GI257900462, Length=479, Percent_Identity=40.9185803757829, Blast_Score=372, Evalue=1e-103,
Organism=Escherichia coli, GI48994936, Length=587, Percent_Identity=44.4633730834753, Blast_Score=484, Evalue=1e-137,
Organism=Escherichia coli, GI2367228, Length=581, Percent_Identity=40.1032702237522, Blast_Score=418, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI32566204, Length=632, Percent_Identity=40.8227848101266, Blast_Score=463, Evalue=1e-130,
Organism=Caenorhabditis elegans, GI17564550, Length=632, Percent_Identity=40.8227848101266, Blast_Score=463, Evalue=1e-130,
Organism=Saccharomyces cerevisiae, GI6325418, Length=630, Percent_Identity=38.4126984126984, Blast_Score=406, Evalue=1e-114,
Organism=Drosophila melanogaster, GI78706832, Length=603, Percent_Identity=40.2985074626866, Blast_Score=442, Evalue=1e-124,
Organism=Drosophila melanogaster, GI24581010, Length=603, Percent_Identity=40.2985074626866, Blast_Score=442, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011833
- InterPro:   IPR000811 [H]

Pfam domain/function: PF00343 Phosphorylase [H]

EC number: =2.4.1.1 [H]

Molecular weight: Translated: 71213; Mature: 71082

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYIFGHFPLDSSAMTENQPLPADLVGSHVRAAAGTPADLATDRKFWTGLSRAVQERIAD
CCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHH
DWERTREAYGAARQQHYFSAEFLMGRALLNNLTNLGLVDEAAATTRELGHELTDILEIEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
DAALGNGGLGRLAACFLDSAVTQDYPVTGYGLLYRFGLFRQSFNEGFQVEKPDPWREEEY
CCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
PFTIRRASDQLVVCFDDMKTRAIPYDMPITGYGTHNVGTLRLWKAEPWEEFDYDAFNSQR
CEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCH
FTDAIIERERVSDICRVLYPNDTTYEGKKLRVRQQYFFTSASLQAMIQGHLAHHKDLSNF
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEFHSVQLNDTHPVLAIPELMRLLMDEHDMGWEESWAIVSKTFAYTNHTVLTEALEQWDQ
HHHHEEEECCCCCCEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
QIFQQLFWRVWEIITEIDRRFRLERAADGLDEETINRMAPIQHGTVHMAWIACYAAYSIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCC
GVAALHTEIIKAETLADWYALWPEKFNNKTNGVTPRRWLRMINPGLSELLTRLSGSDDWV
CHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCHH
TDLDELKKLRSYADDKSVLEELRAIKAANKQDFAEWILERQGIEIDPESIFDVQIKRLHE
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
YKRQLMNALYVLDLYFRIKEDGLTDIPARTVIFGAKAAPGYVRAKAIIKLINSIADLVNN
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEECCCCCCHHHHHHHHHHHHHHHHHHCC
DPEVSPLLKVGFCRELQCLPC
CCCCCHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
GYIFGHFPLDSSAMTENQPLPADLVGSHVRAAAGTPADLATDRKFWTGLSRAVQERIAD
CCEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHH
DWERTREAYGAARQQHYFSAEFLMGRALLNNLTNLGLVDEAAATTRELGHELTDILEIEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
DAALGNGGLGRLAACFLDSAVTQDYPVTGYGLLYRFGLFRQSFNEGFQVEKPDPWREEEY
CCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
PFTIRRASDQLVVCFDDMKTRAIPYDMPITGYGTHNVGTLRLWKAEPWEEFDYDAFNSQR
CEEEEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCH
FTDAIIERERVSDICRVLYPNDTTYEGKKLRVRQQYFFTSASLQAMIQGHLAHHKDLSNF
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEFHSVQLNDTHPVLAIPELMRLLMDEHDMGWEESWAIVSKTFAYTNHTVLTEALEQWDQ
HHHHEEEECCCCCCEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
QIFQQLFWRVWEIITEIDRRFRLERAADGLDEETINRMAPIQHGTVHMAWIACYAAYSIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCC
GVAALHTEIIKAETLADWYALWPEKFNNKTNGVTPRRWLRMINPGLSELLTRLSGSDDWV
CHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCHH
TDLDELKKLRSYADDKSVLEELRAIKAANKQDFAEWILERQGIEIDPESIFDVQIKRLHE
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
YKRQLMNALYVLDLYFRIKEDGLTDIPARTVIFGAKAAPGYVRAKAIIKLINSIADLVNN
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEECCCCCCHHHHHHHHHHHHHHHHHHCC
DPEVSPLLKVGFCRELQCLPC
CCCCCHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3037809; 9278503; 3155826; 2845225; 6283313; 6339728; 6986282; 9009262; 10220320; 10469642 [H]