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The map label for this gene is etfA [H]

Identifier: 145295370

GI number: 145295370

Start: 1439044

End: 1439997

Strand: Direct

Name: etfA [H]

Synonym: cgR_1308

Alternate gene names: 145295370

Gene position: 1439044-1439997 (Clockwise)

Preceding gene: 145295369

Following gene: 145295371

Centisome position: 43.42

GC content: 57.44

Gene sequence:

>954_bases
ATGTCTATTTCTTATGTGCTGGTTGAGCAGCTAGATGGCCGCCCAGAACCAGTTACCCTTGAATTGATCACTGCTGCTCG
CGCACTCGGTGACGTCGTTGCCGTTGTCGTTGGCGAGCCAGGTGCCGGCGTAAACCTTGCTGCTGAGCTCGGCAATTGGG
GTGCAGCACAGGTTGTTTCCGCTGAAGTCTCTGGCGCTTCCAACCGTTTGATCTTGCCTGCTGTTGATGCGCTGCACATT
TTGGCTGCGAACAACCCAGGTCCAATTGTTATCGCTGCAACTGCACGCGGTAATGAGATCGCTGGTCGTTTGGCTGCCCG
TTTGGCTTCTGGTGTGCTCACCGATGTCGTCGGAATCAATGCCGACCGCACCGCACAGCAGTCCATTTTCGGCGACACCA
TTCAGGTGTCCGCTGCAGTTGGTGGCGCTTCACCGCTGTACACCCTGCGTCCAGGTGCCCTTGATGGCGTGGCTGTTCCT
GCAACCGGTGAATTGGCAACCATTGAGATCCCAGGCGCAACCGCCAAGGATGTCACCATCACCTCCTTCACGCCAAGCAC
CCAGAGCGATCGCCCTGAGCTGCCACAGGCAAAGGTCGTTATCGCAGGTGGACGTGGTGTCGGAAGCGAAGAAAACTTCC
GCAGCATCGTTGAACCACTGGCAGATGCATTGGGCGGTGCCGTTGGCGCAACCCGCGACGCCGTTGATCTGGGCTACTAC
CCAGGCGAGTACCAGGTTGGTCAGACCGGTGTCACCGTGTCCCCTGACCTCTACATCGGCCTCGGCATTTCCGGTGCAAT
TCAGCACACTTCTGGTATGCAGACCGCAAAGAAGGTTATTGTGATCAACAACGATGAGGACGCGCCGATCTTCCAGATTG
CGGACCTCGGTGTCGTTGGCGACCTCTTTGACATCGCCCCTGCGCTCATCGAAGAGATCAACAAGCGCAAGTAG

Upstream 100 bases:

>100_bases
GTGATGTCATTGGTGCATCGGGCGCTGCTGAAAAGATCGCTGAGTACCTCGCTTCAGAGAACCTCATCTAGCCACTATCT
TCACAAAGGAGAACATTTAA

Downstream 100 bases:

>100_bases
GAGTTTTGAACACTTTTTATCTGGACCATGCAGCCACCACACCAATGCGTGAGGTGGCCGCAGCTGCGTGGATGGAAAAC
GCGCAGGCATTGAATCCCGC

Product: hypothetical protein

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MSISYVLVEQLDGRPEPVTLELITAARALGDVVAVVVGEPGAGVNLAAELGNWGAAQVVSAEVSGASNRLILPAVDALHI
LAANNPGPIVIAATARGNEIAGRLAARLASGVLTDVVGINADRTAQQSIFGDTIQVSAAVGGASPLYTLRPGALDGVAVP
ATGELATIEIPGATAKDVTITSFTPSTQSDRPELPQAKVVIAGGRGVGSEENFRSIVEPLADALGGAVGATRDAVDLGYY
PGEYQVGQTGVTVSPDLYIGLGISGAIQHTSGMQTAKKVIVINNDEDAPIFQIADLGVVGDLFDIAPALIEEINKRK

Sequences:

>Translated_317_residues
MSISYVLVEQLDGRPEPVTLELITAARALGDVVAVVVGEPGAGVNLAAELGNWGAAQVVSAEVSGASNRLILPAVDALHI
LAANNPGPIVIAATARGNEIAGRLAARLASGVLTDVVGINADRTAQQSIFGDTIQVSAAVGGASPLYTLRPGALDGVAVP
ATGELATIEIPGATAKDVTITSFTPSTQSDRPELPQAKVVIAGGRGVGSEENFRSIVEPLADALGGAVGATRDAVDLGYY
PGEYQVGQTGVTVSPDLYIGLGISGAIQHTSGMQTAKKVIVINNDEDAPIFQIADLGVVGDLFDIAPALIEEINKRK
>Mature_316_residues
SISYVLVEQLDGRPEPVTLELITAARALGDVVAVVVGEPGAGVNLAAELGNWGAAQVVSAEVSGASNRLILPAVDALHIL
AANNPGPIVIAATARGNEIAGRLAARLASGVLTDVVGINADRTAQQSIFGDTIQVSAAVGGASPLYTLRPGALDGVAVPA
TGELATIEIPGATAKDVTITSFTPSTQSDRPELPQAKVVIAGGRGVGSEENFRSIVEPLADALGGAVGATRDAVDLGYYP
GEYQVGQTGVTVSPDLYIGLGISGAIQHTSGMQTAKKVIVINNDEDAPIFQIADLGVVGDLFDIAPALIEEINKRK

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=319, Percent_Identity=37.3040752351097, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI189181759, Length=234, Percent_Identity=40.5982905982906, Blast_Score=169, Evalue=2e-42,
Organism=Escherichia coli, GI1787990, Length=240, Percent_Identity=28.75, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786226, Length=229, Percent_Identity=33.1877729257642, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI87082157, Length=221, Percent_Identity=28.0542986425339, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17506929, Length=320, Percent_Identity=38.125, Blast_Score=163, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6325261, Length=244, Percent_Identity=35.655737704918, Blast_Score=150, Evalue=2e-37,
Organism=Drosophila melanogaster, GI17136898, Length=313, Percent_Identity=36.1022364217252, Blast_Score=165, Evalue=4e-41,
Organism=Drosophila melanogaster, GI24652801, Length=313, Percent_Identity=36.1022364217252, Blast_Score=165, Evalue=4e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 32199; Mature: 32068

Theoretical pI: Translated: 4.19; Mature: 4.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISYVLVEQLDGRPEPVTLELITAARALGDVVAVVVGEPGAGVNLAAELGNWGAAQVVS
CCEEEEEHHHHCCCCCCEEEHHHHHHHHHCCEEEEEECCCCCCCEEEEECCCCCCCEEEE
AEVSGASNRLILPAVDALHILAANNPGPIVIAATARGNEIAGRLAARLASGVLTDVVGIN
EECCCCCCEEEEEECCEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
ADRTAQQSIFGDTIQVSAAVGGASPLYTLRPGALDGVAVPATGELATIEIPGATAKDVTI
CCCHHHHHHCCCEEEEEEECCCCCCEEEECCCCCCCEEECCCCCEEEEEECCCCCCCEEE
TSFTPSTQSDRPELPQAKVVIAGGRGVGSEENFRSIVEPLADALGGAVGATRDAVDLGYY
EEECCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEECCCC
PGEYQVGQTGVTVSPDLYIGLGISGAIQHTSGMQTAKKVIVINNDEDAPIFQIADLGVVG
CCCEEECCCCEEECCCEEEEECCCCHHCCCCCCCCCEEEEEEECCCCCCEEEEECCCHHH
DLFDIAPALIEEINKRK
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SISYVLVEQLDGRPEPVTLELITAARALGDVVAVVVGEPGAGVNLAAELGNWGAAQVVS
CEEEEEHHHHCCCCCCEEEHHHHHHHHHCCEEEEEECCCCCCCEEEEECCCCCCCEEEE
AEVSGASNRLILPAVDALHILAANNPGPIVIAATARGNEIAGRLAARLASGVLTDVVGIN
EECCCCCCEEEEEECCEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
ADRTAQQSIFGDTIQVSAAVGGASPLYTLRPGALDGVAVPATGELATIEIPGATAKDVTI
CCCHHHHHHCCCEEEEEEECCCCCCEEEECCCCCCCEEECCCCCEEEEEECCCCCCCEEE
TSFTPSTQSDRPELPQAKVVIAGGRGVGSEENFRSIVEPLADALGGAVGATRDAVDLGYY
EEECCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEECCCC
PGEYQVGQTGVTVSPDLYIGLGISGAIQHTSGMQTAKKVIVINNDEDAPIFQIADLGVVG
CCCEEECCCCEEECCCEEEEECCCCHHCCCCCCCCCEEEEEEECCCCCCEEEEECCCHHH
DLFDIAPALIEEINKRK
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]