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The map label for this gene is ytfL [C]

Identifier: 145295333

GI number: 145295333

Start: 1400637

End: 1402040

Strand: Reverse

Name: ytfL [C]

Synonym: cgR_1273

Alternate gene names: 145295333

Gene position: 1402040-1400637 (Counterclockwise)

Preceding gene: 145295334

Following gene: 145295332

Centisome position: 42.3

GC content: 49.57

Gene sequence:

>1404_bases
TTGTTAACAGCTATCTTGACTTTAATTGCTGGTTTGGTGGTCATTGGGGTGATCATCGTCATCAACGGATTTTTTGTGGC
TCAAGAATTTGCCTACATGTCCGTTGATCGAAATGAGCTGCGAGCACTCGCTGACTCTGGAAATAAAAAAGCCCGTCGTG
CTCTCAGCATCACTAAGCGCACTTCCTTTATGCTTTCTGGTGCGCAATTGGGTATCACCGTCACCGGACTTTTGGTGGGT
TTTGTGGCCGAACCTCTGGTGGGTAACGCGTTAGGTGTTCTGCTAGGAGGGGTGGGGGTTCCCGCTGCGGTGTCAATCTC
TGTGGGCACTGTGTTGGCGCTAGCGATCTCCACGGTTGTCCAAATGATTTTTGGTGAACTCTTCCCCAAGAACTACACCC
TTGCCACGCCGTTGAAGTCTGCGCTGGCGCTGGCGCCTTCGACCACGTGGTATTTGAAACTCGCTGGTTGGTTGATCACA
TTCTTTGATTTTGCATCCAACGCATTGCTTCGACTCTTTCGAATAGAGCCGGTGGAAGATGTTGATTCGTCTGCCACTGC
ACAAGACCTTCCGCATATTGTGGCGTCATCTAGGGATAGTGGCGTTTTAAATAATTCGATGTCTTTGTCGCTTGATCGAT
TGTTGGATTTCCCGTCGCATGATGTGGGACATGCAATGATTCCGCGTTCGCGTGTGGGTGTGGTTGATCCGGAGACAACC
ATCGCTGAGGTTAAGGCCCTCATGAGGAAAGCGCATACGCGTTACCCCATCATCGATGACAACCATGTGCCCATTGGGGT
GATCAATCTGATTGATATTCTTGGAACCGATATTCACGGCGCCGAAATTTCAGATTCCGCGAAAGTCACTGAGTTCATGC
ATCAGCCTGTGATCGTTCCAGAGTTTATGTCTTTGCCTGACGTGGTGACCGAACTGCACAATCGTGAAGACAAGCTTGCT
TGCGTGATTGATGAATACGGTGGATTCATTGGCATTGTGACATTAGAAGATTTAGCTGAGGAAGTCCTCGGCGATATCAA
CGATGAGCACGATGTTTTCAGCTCTGAAGATATTACGGAAACGAGCCCTGACAAATGGCTAATTGATGGCGATACCCCTC
TTGACGAGGTTGAGCGCGCCATCGGGTACGAGCTACCTGAAGGCGATTACGAGACGATTTCTGGACTGCTCTTTGACCAT
GCGAATGCCCTTCTAAAGACTGGGGATGTCATAGAAATACCTCTGGATTTTGAGCCAGAGGATTACCTAAACAACACTTC
CCCTACGCAGCGTATTTTGCGCATCACTGTTTTAGAGGTAGAGCGAAACGTGCCTGTAAAACTGGCGCTCGCTCTGCTCG
AAGACCACCCAGACAATCACCCCGCTCCGAAGGAGAATCGCTAA

Upstream 100 bases:

>100_bases
ACCGACTTAAATGAATGAGGTTTAGACTCCAAATGGAGCCTCCCGCACGATCTATCTGGCCTGTCCACACTAATCTATTT
GTGTTGAGGCAGGTGGAACC

Downstream 100 bases:

>100_bases
GCCATGACTGAATGGTATGTCGTTTTACCCGCCACTATTCTACTCATCGCGCTGTCTGCGTTTTTCGTCATCATTGAGTT
CGCTTTGCTTGCAGCTAGGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MLTAILTLIAGLVVIGVIIVINGFFVAQEFAYMSVDRNELRALADSGNKKARRALSITKRTSFMLSGAQLGITVTGLLVG
FVAEPLVGNALGVLLGGVGVPAAVSISVGTVLALAISTVVQMIFGELFPKNYTLATPLKSALALAPSTTWYLKLAGWLIT
FFDFASNALLRLFRIEPVEDVDSSATAQDLPHIVASSRDSGVLNNSMSLSLDRLLDFPSHDVGHAMIPRSRVGVVDPETT
IAEVKALMRKAHTRYPIIDDNHVPIGVINLIDILGTDIHGAEISDSAKVTEFMHQPVIVPEFMSLPDVVTELHNREDKLA
CVIDEYGGFIGIVTLEDLAEEVLGDINDEHDVFSSEDITETSPDKWLIDGDTPLDEVERAIGYELPEGDYETISGLLFDH
ANALLKTGDVIEIPLDFEPEDYLNNTSPTQRILRITVLEVERNVPVKLALALLEDHPDNHPAPKENR

Sequences:

>Translated_467_residues
MLTAILTLIAGLVVIGVIIVINGFFVAQEFAYMSVDRNELRALADSGNKKARRALSITKRTSFMLSGAQLGITVTGLLVG
FVAEPLVGNALGVLLGGVGVPAAVSISVGTVLALAISTVVQMIFGELFPKNYTLATPLKSALALAPSTTWYLKLAGWLIT
FFDFASNALLRLFRIEPVEDVDSSATAQDLPHIVASSRDSGVLNNSMSLSLDRLLDFPSHDVGHAMIPRSRVGVVDPETT
IAEVKALMRKAHTRYPIIDDNHVPIGVINLIDILGTDIHGAEISDSAKVTEFMHQPVIVPEFMSLPDVVTELHNREDKLA
CVIDEYGGFIGIVTLEDLAEEVLGDINDEHDVFSSEDITETSPDKWLIDGDTPLDEVERAIGYELPEGDYETISGLLFDH
ANALLKTGDVIEIPLDFEPEDYLNNTSPTQRILRITVLEVERNVPVKLALALLEDHPDNHPAPKENR
>Mature_467_residues
MLTAILTLIAGLVVIGVIIVINGFFVAQEFAYMSVDRNELRALADSGNKKARRALSITKRTSFMLSGAQLGITVTGLLVG
FVAEPLVGNALGVLLGGVGVPAAVSISVGTVLALAISTVVQMIFGELFPKNYTLATPLKSALALAPSTTWYLKLAGWLIT
FFDFASNALLRLFRIEPVEDVDSSATAQDLPHIVASSRDSGVLNNSMSLSLDRLLDFPSHDVGHAMIPRSRVGVVDPETT
IAEVKALMRKAHTRYPIIDDNHVPIGVINLIDILGTDIHGAEISDSAKVTEFMHQPVIVPEFMSLPDVVTELHNREDKLA
CVIDEYGGFIGIVTLEDLAEEVLGDINDEHDVFSSEDITETSPDKWLIDGDTPLDEVERAIGYELPEGDYETISGLLFDH
ANALLKTGDVIEIPLDFEPEDYLNNTSPTQRILRITVLEVERNVPVKLALALLEDHPDNHPAPKENR

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=399, Percent_Identity=27.0676691729323, Blast_Score=161, Evalue=2e-39,
Organism=Escherichia coli, GI1790664, Length=410, Percent_Identity=24.1463414634146, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI145693175, Length=395, Percent_Identity=26.0759493670886, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI87082033, Length=353, Percent_Identity=23.5127478753541, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1786879, Length=307, Percent_Identity=27.0358306188925, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 50744; Mature: 50744

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTAILTLIAGLVVIGVIIVINGFFVAQEFAYMSVDRNELRALADSGNKKARRALSITKR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHH
TSFMLSGAQLGITVTGLLVGFVAEPLVGNALGVLLGGVGVPAAVSISVGTVLALAISTVV
HHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHH
QMIFGELFPKNYTLATPLKSALALAPSTTWYLKLAGWLITFFDFASNALLRLFRIEPVED
HHHHHHHCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VDSSATAQDLPHIVASSRDSGVLNNSMSLSLDRLLDFPSHDVGHAMIPRSRVGVVDPETT
CCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHH
IAEVKALMRKAHTRYPIIDDNHVPIGVINLIDILGTDIHGAEISDSAKVTEFMHQPVIVP
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCH
EFMSLPDVVTELHNREDKLACVIDEYGGFIGIVTLEDLAEEVLGDINDEHDVFSSEDITE
HHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCC
TSPDKWLIDGDTPLDEVERAIGYELPEGDYETISGLLFDHANALLKTGDVIEIPLDFEPE
CCCCCEEECCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCH
DYLNNTSPTQRILRITVLEVERNVPVKLALALLEDHPDNHPAPKENR
HHCCCCCHHHHHHHHEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MLTAILTLIAGLVVIGVIIVINGFFVAQEFAYMSVDRNELRALADSGNKKARRALSITKR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHH
TSFMLSGAQLGITVTGLLVGFVAEPLVGNALGVLLGGVGVPAAVSISVGTVLALAISTVV
HHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHH
QMIFGELFPKNYTLATPLKSALALAPSTTWYLKLAGWLITFFDFASNALLRLFRIEPVED
HHHHHHHCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VDSSATAQDLPHIVASSRDSGVLNNSMSLSLDRLLDFPSHDVGHAMIPRSRVGVVDPETT
CCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHH
IAEVKALMRKAHTRYPIIDDNHVPIGVINLIDILGTDIHGAEISDSAKVTEFMHQPVIVP
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCH
EFMSLPDVVTELHNREDKLACVIDEYGGFIGIVTLEDLAEEVLGDINDEHDVFSSEDITE
HHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCC
TSPDKWLIDGDTPLDEVERAIGYELPEGDYETISGLLFDHANALLKTGDVIEIPLDFEPE
CCCCCEEECCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCH
DYLNNTSPTQRILRITVLEVERNVPVKLALALLEDHPDNHPAPKENR
HHCCCCCHHHHHHHHEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]