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The map label for this gene is kgd [H]

Identifier: 145295272

GI number: 145295272

Start: 1314998

End: 1318771

Strand: Reverse

Name: kgd [H]

Synonym: cgR_1213

Alternate gene names: 145295272

Gene position: 1318771-1314998 (Counterclockwise)

Preceding gene: 145295273

Following gene: 145295271

Centisome position: 39.79

GC content: 58.69

Gene sequence:

>3774_bases
ATGCTACAACTGGGGCTTAGGCATAATCAGCCAACAACCAGCGTTACAGTGGATAAAACAAAGCTCAATAAACCCTCAAG
AAGCAAGGAAAAGAGGCGAGTACCTGCCGTGAGCAGCGCTAGTACTTTCGGCCAGAATGCGTGGCTGGTAGACGAGATGT
TCCAGCAGTTCCAGAAGGACCCCAAGTCCGTGGACAAGGAATGGAGAGAACTCTTTGAGGCGCAGGGGGGACCAAATACT
ACCCCCGCTACAACAGAAGCACAGCCTTCAGCGCCCAAGGAGTCTGCGAAACCAGCACCAAAGGCTGCCCCTGCAGCCAA
GGCAGCACCGCGCGTAGAAACCAAGCCGGCCGCCAAGGCCGCCCCAAAGGCCAAGGAGTCCTCAGTGCCACAGCAACCTA
AGCTTCCGGAGCCAGGACAAACCCCAATCAGGGGTATTTTCAAGTCCATCGCGAAGAACATGGATATCTCCCTGGAAATC
CCAACCGCAACCTCGGTTCGCGATATGCCAGCTCGCCTCATGTTCGAAAACCGCGCGATGGTCAACGATCAGCTCAAGCG
CACCCGCGGTGGCAAGATCTCCTTCACCCACATCATTGGCTACGCCATGGTGAAGGCAGTCATGGCTCACCCGGACATGA
ACAACTCCTACGACGTCATCGACGGCAAGCCAACCCTGATCGTGCCTGAGCACATCAACCTGGGCCTTGCTATCGACCTT
CCTCAGAAGGACGGCTCCCGCGCACTTGTCGTAGCAGCCATCAAGGAAACCGAGAAGATGAACTTCTCCGAGTTCCTCGC
AGCATACGAAGACATCGTGACACGCTCCCGCAAGGGCAAGCTCACCATGGATGACTACCAGGGCGTTACCGTTTCCTTGA
CCAACCCAGGTGGCATCGGTACCCGCCACTCTGTCCCACGTCTGACCAAGGGCCAGGGCACCATCATCGGTGTCGGTTCC
ATGGATTACCCAGCAGAGTTCCAGGGCGCTTCCGAAGACCGCCTTGCAGAGCTCGGCGTTGGCAAGCTAGTAACCATCAC
CTCCACCTACGATCACCGCGTGATCCAGGGTGCTGTGTCCGGTGAATTCCTGCGCACCATGTCTCGCCTGCTCACCGATG
ATTCCTTCTGGGATGAGATCTTCGACGCAATGAACGTTCCTTACACCCCAATGCGTTGGGCACAGGACGTTCCAAACACC
GGTGTTGATAAGAACACCCGCGTCATGCAGCTCATTGAGGCATACCGCTCCCGTGGACACCTCATCGCTGACACCAACCC
ACTTTCATGGGTTCAGCCTGGCATGCCAGTTCCAGACCACCGCGACCTCGACATCGAGACCCACGGCCTGACCATCTGGG
ATCTGGACCGTACCTTCAGCGTCGGTGGCTTCGGCGGCAAGGAGACCATGACCCTGCGCGAGGTACTGTCCCGCCTCCGC
GCTGCGTACACCCTCAAGGTCGGCTCCGAATACACCCACATCCTGGACCGCGACGAGCGCACCTGGCTGCAGGACCGCCT
CGAAGCAGGTATGCCAAAGCCAACCCAGGCAGAGCAGAAGTACATCCTGCAGAAGCTGAACGCCGCGGAGGCTTTCGAGA
ACTTCCTGCAGACCAAGTACGTCGGCCAGAAGCGCTTCTCCCTCGAAGGTGCAGAAGCACTTATCCCACTGATGGACTCC
GCCATCGACACCGCCGCAGGCCAGGGCCTCGACGAAGTTGTCATCGGTATGCCACACCGTGGACGCCTCAACGTGCTGTT
CAACATCGTGGGCAAGCCACTGGCATCCATCTTCAACGAGTTTGAAGGCCAAATGGAGCAGGGCCAGATCGGTGGCTCCG
GTGACGTGAAGTACCACCTCGGTTCCGAAGGCCAGCACCTGCAGATGTTCGGCGACGGCGAGATCAAGGTCTCCCTGACT
GCTAACCCGTCCCACCTGGAAGCTGTTAACCCAGTGATGGAAGGTATCGTCCGCGCAAAGCAGGACTACCTGGACAAGGG
CGTAGACGGCAAGACTGTTGTGCCACTGCTGCTCCACGGTGACGCTGCATTCGCAGGCCTGGGCATCGTGCCAGAAACCA
TCAACCTGGCTAAGCTGCGTGGCTACGACGTCGGCGGCACCATCCACATCGTGGTGAACAACCAGATCGGCTTCACCACC
ACCCCAGACTCCAGCCGCTCCATGCACTACGCAACCGACTACGCCAAGGCATTCGGCTGCCCAGTCTTCCACGTCAATGG
TGATGACCCAGAGGCAGTTGTCTGGGTTGGCCAGCTGGCCACCGAGTACCGTCGTCGCTTCGGCAAGGACGTCTTCATCG
ACCTCGTTTGCTACCGCCTCCGCGGCCACAACGAAGCTGATGATCCTTCCATGACCCAGCCAAAGATGTATGAGCTCATC
ACCGGCCGCGAGACCGTTCGTGCTCAGTACACCGAAGACCTGCTCGGACGTGGAGACCTCTCCAACGAAGATGCAGAAGC
AGTCGTCCGCGACTTCCACGACCAGATGGAATCTGTGTTCAACGAAGTCAAGGAAGGCGGCAAGAAGCAGGCTGAGGCAC
AGACCGGCATCACCGGCTCCCAGAAGCTTCCACACGGCCTTGAGACCAACATCTCCCGTGAAGAGCTCCTGGAACTGGGA
CAGGCTTTCGCCAACACCCCAGAAGGCTTCAACTACCACCCACGTGTGGCTCCCGTTGCTAAGAAGCGCGTCTCCTCTGT
CACCGAAGGTGGCATCGACTGGGCATGGGGCGAGCTCCTCGCCTTCGGTTCCCTAGCTAACTCCGGCCGCTTGGTTCGCC
TTGCAGGTGAGGATTCCCGCCGCGGTACCTTCACCCAGCGCCACGCAGTTGCCATCGACCCAGCGACCGCTGAAGAGTTC
AACCCACTCCACGAGCTTGCACAGTCCAAGGGCAACAACGGTAAGTTCCTGGTCTACAACTCCGCACTGACCGAGTACGC
AGGCATGGGCTTCGAGTACGGCTACTCCGTAGGAAACGAAGACTCCGTCGTTGCATGGGAAGCACAGTTCGGCGACTTCG
CCAACGGCGCTCAGACCATCATCGATGAGTACGTCTCCTCAGGCGAAGCTAAGTGGGGCCAGACCTCCAAGCTGATCCTT
CTGCTGCCTCACGGCTACGAAGGCCAGGGCCCAGACCACTCTTCCGCACGTATCGAGCGCTTCCTGCAGCTGTGCGCTGA
GGGTTCCATGACTGTTGCTCAGCCATCCACCCCAGCAAACCACTTCCACCTGCTGCGTCGTCACGCTCTGTCCGACCTGA
AGCGTCCACTGGTTATCTTCACCCCGAAGTCCATGCTGCGTAACAAGGCTGCTGCCTCCGCACCAGAAGACTTCACTGAG
GTCACCAAGTTCCAATCCGTGATCGACGATCCAAACGTTGCAGATGCAGCCAAGGTGAAGAAGGTCATGCTGGTCTCCGG
CAAGCTGTACTACGAATTGGCAAAGCGCAAGGAGAAGGACGGACGCGACGACATCGCGATCGTTCGTATCGAAATGCTCC
ACCCAATTCCGTTCAACCGCATCTCCGAGGCTCTTGCCGGCTACCCTAACGCTGAGGAAGTTCTCTTCGTTCAGGATGAG
CCAGCAAACCAGGGCCCATGGCCGTTCTACCAGGAGCACCTCCCAGCGCTGATCCCGAACATGCCAAAGATGCGCCGCGT
TTCCCGCCGCGCTCAGTCCTCCACCGCAACTGGTGTTGCTAAGGTGCACCAGCTGGAGGAGAAGCAGCTTATCGACGAGG
CTTTCGAGGCTTAA

Upstream 100 bases:

>100_bases
CGGATCTCACGACGCGTTGTTGTCTGCTAACGGCACCTACGCCCGCATGTGGCATTTAATGGCCTGACACGTTATTTTTA
GGAGAACTGTCAACAAATTA

Downstream 100 bases:

>100_bases
GTCTTTATAGTCCTGCACTAGCCTAGAAGGGCCTTATGCGGTGTGAATCACACAGCATAAGGCCCTTTTTTGCTGCCGTG
GTTGCCTAAGGTGGAAGGCA

Product: alpha-ketoglutarate decarboxylase

Products: NA

Alternate protein names: Alpha-ketoglutarate dehydrogenase [H]

Number of amino acids: Translated: 1257; Mature: 1257

Protein sequence:

>1257_residues
MLQLGLRHNQPTTSVTVDKTKLNKPSRSKEKRRVPAVSSASTFGQNAWLVDEMFQQFQKDPKSVDKEWRELFEAQGGPNT
TPATTEAQPSAPKESAKPAPKAAPAAKAAPRVETKPAAKAAPKAKESSVPQQPKLPEPGQTPIRGIFKSIAKNMDISLEI
PTATSVRDMPARLMFENRAMVNDQLKRTRGGKISFTHIIGYAMVKAVMAHPDMNNSYDVIDGKPTLIVPEHINLGLAIDL
PQKDGSRALVVAAIKETEKMNFSEFLAAYEDIVTRSRKGKLTMDDYQGVTVSLTNPGGIGTRHSVPRLTKGQGTIIGVGS
MDYPAEFQGASEDRLAELGVGKLVTITSTYDHRVIQGAVSGEFLRTMSRLLTDDSFWDEIFDAMNVPYTPMRWAQDVPNT
GVDKNTRVMQLIEAYRSRGHLIADTNPLSWVQPGMPVPDHRDLDIETHGLTIWDLDRTFSVGGFGGKETMTLREVLSRLR
AAYTLKVGSEYTHILDRDERTWLQDRLEAGMPKPTQAEQKYILQKLNAAEAFENFLQTKYVGQKRFSLEGAEALIPLMDS
AIDTAAGQGLDEVVIGMPHRGRLNVLFNIVGKPLASIFNEFEGQMEQGQIGGSGDVKYHLGSEGQHLQMFGDGEIKVSLT
ANPSHLEAVNPVMEGIVRAKQDYLDKGVDGKTVVPLLLHGDAAFAGLGIVPETINLAKLRGYDVGGTIHIVVNNQIGFTT
TPDSSRSMHYATDYAKAFGCPVFHVNGDDPEAVVWVGQLATEYRRRFGKDVFIDLVCYRLRGHNEADDPSMTQPKMYELI
TGRETVRAQYTEDLLGRGDLSNEDAEAVVRDFHDQMESVFNEVKEGGKKQAEAQTGITGSQKLPHGLETNISREELLELG
QAFANTPEGFNYHPRVAPVAKKRVSSVTEGGIDWAWGELLAFGSLANSGRLVRLAGEDSRRGTFTQRHAVAIDPATAEEF
NPLHELAQSKGNNGKFLVYNSALTEYAGMGFEYGYSVGNEDSVVAWEAQFGDFANGAQTIIDEYVSSGEAKWGQTSKLIL
LLPHGYEGQGPDHSSARIERFLQLCAEGSMTVAQPSTPANHFHLLRRHALSDLKRPLVIFTPKSMLRNKAAASAPEDFTE
VTKFQSVIDDPNVADAAKVKKVMLVSGKLYYELAKRKEKDGRDDIAIVRIEMLHPIPFNRISEALAGYPNAEEVLFVQDE
PANQGPWPFYQEHLPALIPNMPKMRRVSRRAQSSTATGVAKVHQLEEKQLIDEAFEA

Sequences:

>Translated_1257_residues
MLQLGLRHNQPTTSVTVDKTKLNKPSRSKEKRRVPAVSSASTFGQNAWLVDEMFQQFQKDPKSVDKEWRELFEAQGGPNT
TPATTEAQPSAPKESAKPAPKAAPAAKAAPRVETKPAAKAAPKAKESSVPQQPKLPEPGQTPIRGIFKSIAKNMDISLEI
PTATSVRDMPARLMFENRAMVNDQLKRTRGGKISFTHIIGYAMVKAVMAHPDMNNSYDVIDGKPTLIVPEHINLGLAIDL
PQKDGSRALVVAAIKETEKMNFSEFLAAYEDIVTRSRKGKLTMDDYQGVTVSLTNPGGIGTRHSVPRLTKGQGTIIGVGS
MDYPAEFQGASEDRLAELGVGKLVTITSTYDHRVIQGAVSGEFLRTMSRLLTDDSFWDEIFDAMNVPYTPMRWAQDVPNT
GVDKNTRVMQLIEAYRSRGHLIADTNPLSWVQPGMPVPDHRDLDIETHGLTIWDLDRTFSVGGFGGKETMTLREVLSRLR
AAYTLKVGSEYTHILDRDERTWLQDRLEAGMPKPTQAEQKYILQKLNAAEAFENFLQTKYVGQKRFSLEGAEALIPLMDS
AIDTAAGQGLDEVVIGMPHRGRLNVLFNIVGKPLASIFNEFEGQMEQGQIGGSGDVKYHLGSEGQHLQMFGDGEIKVSLT
ANPSHLEAVNPVMEGIVRAKQDYLDKGVDGKTVVPLLLHGDAAFAGLGIVPETINLAKLRGYDVGGTIHIVVNNQIGFTT
TPDSSRSMHYATDYAKAFGCPVFHVNGDDPEAVVWVGQLATEYRRRFGKDVFIDLVCYRLRGHNEADDPSMTQPKMYELI
TGRETVRAQYTEDLLGRGDLSNEDAEAVVRDFHDQMESVFNEVKEGGKKQAEAQTGITGSQKLPHGLETNISREELLELG
QAFANTPEGFNYHPRVAPVAKKRVSSVTEGGIDWAWGELLAFGSLANSGRLVRLAGEDSRRGTFTQRHAVAIDPATAEEF
NPLHELAQSKGNNGKFLVYNSALTEYAGMGFEYGYSVGNEDSVVAWEAQFGDFANGAQTIIDEYVSSGEAKWGQTSKLIL
LLPHGYEGQGPDHSSARIERFLQLCAEGSMTVAQPSTPANHFHLLRRHALSDLKRPLVIFTPKSMLRNKAAASAPEDFTE
VTKFQSVIDDPNVADAAKVKKVMLVSGKLYYELAKRKEKDGRDDIAIVRIEMLHPIPFNRISEALAGYPNAEEVLFVQDE
PANQGPWPFYQEHLPALIPNMPKMRRVSRRAQSSTATGVAKVHQLEEKQLIDEAFEA
>Mature_1257_residues
MLQLGLRHNQPTTSVTVDKTKLNKPSRSKEKRRVPAVSSASTFGQNAWLVDEMFQQFQKDPKSVDKEWRELFEAQGGPNT
TPATTEAQPSAPKESAKPAPKAAPAAKAAPRVETKPAAKAAPKAKESSVPQQPKLPEPGQTPIRGIFKSIAKNMDISLEI
PTATSVRDMPARLMFENRAMVNDQLKRTRGGKISFTHIIGYAMVKAVMAHPDMNNSYDVIDGKPTLIVPEHINLGLAIDL
PQKDGSRALVVAAIKETEKMNFSEFLAAYEDIVTRSRKGKLTMDDYQGVTVSLTNPGGIGTRHSVPRLTKGQGTIIGVGS
MDYPAEFQGASEDRLAELGVGKLVTITSTYDHRVIQGAVSGEFLRTMSRLLTDDSFWDEIFDAMNVPYTPMRWAQDVPNT
GVDKNTRVMQLIEAYRSRGHLIADTNPLSWVQPGMPVPDHRDLDIETHGLTIWDLDRTFSVGGFGGKETMTLREVLSRLR
AAYTLKVGSEYTHILDRDERTWLQDRLEAGMPKPTQAEQKYILQKLNAAEAFENFLQTKYVGQKRFSLEGAEALIPLMDS
AIDTAAGQGLDEVVIGMPHRGRLNVLFNIVGKPLASIFNEFEGQMEQGQIGGSGDVKYHLGSEGQHLQMFGDGEIKVSLT
ANPSHLEAVNPVMEGIVRAKQDYLDKGVDGKTVVPLLLHGDAAFAGLGIVPETINLAKLRGYDVGGTIHIVVNNQIGFTT
TPDSSRSMHYATDYAKAFGCPVFHVNGDDPEAVVWVGQLATEYRRRFGKDVFIDLVCYRLRGHNEADDPSMTQPKMYELI
TGRETVRAQYTEDLLGRGDLSNEDAEAVVRDFHDQMESVFNEVKEGGKKQAEAQTGITGSQKLPHGLETNISREELLELG
QAFANTPEGFNYHPRVAPVAKKRVSSVTEGGIDWAWGELLAFGSLANSGRLVRLAGEDSRRGTFTQRHAVAIDPATAEEF
NPLHELAQSKGNNGKFLVYNSALTEYAGMGFEYGYSVGNEDSVVAWEAQFGDFANGAQTIIDEYVSSGEAKWGQTSKLIL
LLPHGYEGQGPDHSSARIERFLQLCAEGSMTVAQPSTPANHFHLLRRHALSDLKRPLVIFTPKSMLRNKAAASAPEDFTE
VTKFQSVIDDPNVADAAKVKKVMLVSGKLYYELAKRKEKDGRDDIAIVRIEMLHPIPFNRISEALAGYPNAEEVLFVQDE
PANQGPWPFYQEHLPALIPNMPKMRRVSRRAQSSTATGVAKVHQLEEKQLIDEAFEA

Specific function: The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components:2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2)

COG id: COG0567

COG function: function code C; 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alpha-ketoglutarate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI259013553, Length=902, Percent_Identity=39.3569844789357, Blast_Score=629, Evalue=1e-180,
Organism=Homo sapiens, GI51873036, Length=901, Percent_Identity=39.2896781354051, Blast_Score=628, Evalue=1e-180,
Organism=Homo sapiens, GI221316661, Length=899, Percent_Identity=38.0422691879866, Blast_Score=607, Evalue=1e-173,
Organism=Homo sapiens, GI221316665, Length=887, Percent_Identity=37.880496054115, Blast_Score=598, Evalue=1e-170,
Organism=Homo sapiens, GI221316669, Length=798, Percent_Identity=38.9724310776942, Blast_Score=568, Evalue=1e-161,
Organism=Homo sapiens, GI38788380, Length=876, Percent_Identity=36.6438356164384, Blast_Score=544, Evalue=1e-154,
Organism=Homo sapiens, GI51873038, Length=284, Percent_Identity=39.4366197183099, Blast_Score=196, Evalue=1e-49,
Organism=Homo sapiens, GI19923748, Length=199, Percent_Identity=26.6331658291457, Blast_Score=71, Evalue=7e-12,
Organism=Escherichia coli, GI1786945, Length=866, Percent_Identity=44.2263279445727, Blast_Score=708, Evalue=0.0,
Organism=Escherichia coli, GI1786946, Length=211, Percent_Identity=23.696682464455, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1786305, Length=188, Percent_Identity=29.2553191489362, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17542494, Length=900, Percent_Identity=41, Blast_Score=658, Evalue=0.0,
Organism=Caenorhabditis elegans, GI72001668, Length=880, Percent_Identity=36.4772727272727, Blast_Score=546, Evalue=1e-155,
Organism=Saccharomyces cerevisiae, GI6322066, Length=952, Percent_Identity=39.4957983193277, Blast_Score=657, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6320352, Length=296, Percent_Identity=23.3108108108108, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28574590, Length=902, Percent_Identity=39.5787139689579, Blast_Score=628, Evalue=1e-180,
Organism=Drosophila melanogaster, GI161084450, Length=902, Percent_Identity=39.5787139689579, Blast_Score=628, Evalue=1e-180,
Organism=Drosophila melanogaster, GI24665669, Length=893, Percent_Identity=39.9776035834266, Blast_Score=628, Evalue=1e-180,
Organism=Drosophila melanogaster, GI24665673, Length=893, Percent_Identity=39.9776035834266, Blast_Score=628, Evalue=1e-180,
Organism=Drosophila melanogaster, GI24665677, Length=893, Percent_Identity=39.9776035834266, Blast_Score=628, Evalue=1e-180,
Organism=Drosophila melanogaster, GI28574592, Length=893, Percent_Identity=39.9776035834266, Blast_Score=628, Evalue=1e-180,
Organism=Drosophila melanogaster, GI161084461, Length=867, Percent_Identity=40.1384083044983, Blast_Score=617, Evalue=1e-176,
Organism=Drosophila melanogaster, GI281365454, Length=903, Percent_Identity=38.7596899224806, Blast_Score=602, Evalue=1e-172,
Organism=Drosophila melanogaster, GI281365452, Length=903, Percent_Identity=38.7596899224806, Blast_Score=602, Evalue=1e-172,
Organism=Drosophila melanogaster, GI78706592, Length=903, Percent_Identity=38.7596899224806, Blast_Score=602, Evalue=1e-172,
Organism=Drosophila melanogaster, GI78706596, Length=903, Percent_Identity=38.7596899224806, Blast_Score=602, Evalue=1e-172,
Organism=Drosophila melanogaster, GI78706594, Length=924, Percent_Identity=37.7705627705628, Blast_Score=589, Evalue=1e-168,
Organism=Drosophila melanogaster, GI78706598, Length=924, Percent_Identity=37.7705627705628, Blast_Score=589, Evalue=1e-168,
Organism=Drosophila melanogaster, GI24651589, Length=891, Percent_Identity=36.9248035914703, Blast_Score=541, Evalue=1e-154,
Organism=Drosophila melanogaster, GI161079314, Length=747, Percent_Identity=39.4912985274431, Blast_Score=510, Evalue=1e-144,
Organism=Drosophila melanogaster, GI24651591, Length=747, Percent_Identity=39.4912985274431, Blast_Score=510, Evalue=1e-144,
Organism=Drosophila melanogaster, GI24645909, Length=201, Percent_Identity=26.865671641791, Blast_Score=72, Evalue=2e-12,

Paralogues:

None

Copy number: 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001078
- InterPro:   IPR011603
- InterPro:   IPR023213
- InterPro:   IPR001017
- InterPro:   IPR005475 [H]

Pfam domain/function: PF00198 2-oxoacid_dh; PF00676 E1_dh; PF02779 Transket_pyr [H]

EC number: =1.2.4.2 [H]

Molecular weight: Translated: 138532; Mature: 138532

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS00290 IG_MHC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQLGLRHNQPTTSVTVDKTKLNKPSRSKEKRRVPAVSSASTFGQNAWLVDEMFQQFQKD
CCEECCCCCCCCCEEEEEHHHCCCCCCCHHHHCCCCCCCHHHCCCCCHHHHHHHHHHHCC
PKSVDKEWRELFEAQGGPNTTPATTEAQPSAPKESAKPAPKAAPAAKAAPRVETKPAAKA
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCHHC
APKAKESSVPQQPKLPEPGQTPIRGIFKSIAKNMDISLEIPTATSVRDMPARLMFENRAM
CCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCHHCCHHHHHHCHHH
VNDQLKRTRGGKISFTHIIGYAMVKAVMAHPDMNNSYDVIDGKPTLIVPEHINLGLAIDL
HHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEECCCCCEEEEEEC
PQKDGSRALVVAAIKETEKMNFSEFLAAYEDIVTRSRKGKLTMDDYQGVTVSLTNPGGIG
CCCCCCCEEEEEEEHHHHCCCHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEECCCCCC
TRHSVPRLTKGQGTIIGVGSMDYPAEFQGASEDRLAELGVGKLVTITSTYDHRVIQGAVS
CCCCCCCCCCCCCCEEEECCCCCCHHCCCCCHHHHHHCCCCCEEEEECCCCCHHHHHHHH
GEFLRTMSRLLTDDSFWDEIFDAMNVPYTPMRWAQDVPNTGVDKNTRVMQLIEAYRSRGH
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHCCC
LIADTNPLSWVQPGMPVPDHRDLDIETHGLTIWDLDRTFSVGGFGGKETMTLREVLSRLR
EEECCCCCCCCCCCCCCCCCCCCCEEECCEEEEECCCEEECCCCCCCHHHHHHHHHHHHH
AAYTLKVGSEYTHILDRDERTWLQDRLEAGMPKPTQAEQKYILQKLNAAEAFENFLQTKY
HHEEEEECCHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VGQKRFSLEGAEALIPLMDSAIDTAAGQGLDEVVIGMPHRGRLNVLFNIVGKPLASIFNE
CCCHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
FEGQMEQGQIGGSGDVKYHLGSEGQHLQMFGDGEIKVSLTANPSHLEAVNPVMEGIVRAK
HCCCHHCCCCCCCCCEEEEECCCCCEEEEEECCEEEEEEECCCHHHHHHHHHHHHHHHHH
QDYLDKGVDGKTVVPLLLHGDAAFAGLGIVPETINLAKLRGYDVGGTIHIVVNNQIGFTT
HHHHHCCCCCCEEEEEEEECCHHHHCCCCCCCCCCHHHCCCCCCCCEEEEEEECCCCCEE
TPDSSRSMHYATDYAKAFGCPVFHVNGDDPEAVVWVGQLATEYRRRFGKDVFIDLVCYRL
CCCCCCCEEHHHHHHHHHCCCEEEECCCCCCEEEEHHHHHHHHHHHHCCHHHHHHHHHHH
RGHNEADDPSMTQPKMYELITGRETVRAQYTEDLLGRGDLSNEDAEAVVRDFHDQMESVF
CCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
NEVKEGGKKQAEAQTGITGSQKLPHGLETNISREELLELGQAFANTPEGFNYHPRVAPVA
HHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHH
KKRVSSVTEGGIDWAWGELLAFGSLANSGRLVRLAGEDSRRGTFTQRHAVAIDPATAEEF
HHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCEEEECCCCHHHC
NPLHELAQSKGNNGKFLVYNSALTEYAGMGFEYGYSVGNEDSVVAWEAQFGDFANGAQTI
CHHHHHHHCCCCCCCEEEECCHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHH
IDEYVSSGEAKWGQTSKLILLLPHGYEGQGPDHSSARIERFLQLCAEGSMTVAQPSTPAN
HHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCHH
HFHLLRRHALSDLKRPLVIFTPKSMLRNKAAASAPEDFTEVTKFQSVIDDPNVADAAKVK
HHHHHHHHHHHHHCCCEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHH
KVMLVSGKLYYELAKRKEKDGRDDIAIVRIEMLHPIPFNRISEALAGYPNAEEVLFVQDE
HHHHHCCHHHHHHHHHHCCCCCCCEEEEEEEEECCCCHHHHHHHHCCCCCCCCEEEEECC
PANQGPWPFYQEHLPALIPNMPKMRRVSRRAQSSTATGVAKVHQLEEKQLIDEAFEA
CCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLQLGLRHNQPTTSVTVDKTKLNKPSRSKEKRRVPAVSSASTFGQNAWLVDEMFQQFQKD
CCEECCCCCCCCCEEEEEHHHCCCCCCCHHHHCCCCCCCHHHCCCCCHHHHHHHHHHHCC
PKSVDKEWRELFEAQGGPNTTPATTEAQPSAPKESAKPAPKAAPAAKAAPRVETKPAAKA
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCHHC
APKAKESSVPQQPKLPEPGQTPIRGIFKSIAKNMDISLEIPTATSVRDMPARLMFENRAM
CCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCHHCCHHHHHHCHHH
VNDQLKRTRGGKISFTHIIGYAMVKAVMAHPDMNNSYDVIDGKPTLIVPEHINLGLAIDL
HHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEECCCCCEEEEEEC
PQKDGSRALVVAAIKETEKMNFSEFLAAYEDIVTRSRKGKLTMDDYQGVTVSLTNPGGIG
CCCCCCCEEEEEEEHHHHCCCHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEECCCCCC
TRHSVPRLTKGQGTIIGVGSMDYPAEFQGASEDRLAELGVGKLVTITSTYDHRVIQGAVS
CCCCCCCCCCCCCCEEEECCCCCCHHCCCCCHHHHHHCCCCCEEEEECCCCCHHHHHHHH
GEFLRTMSRLLTDDSFWDEIFDAMNVPYTPMRWAQDVPNTGVDKNTRVMQLIEAYRSRGH
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHCCC
LIADTNPLSWVQPGMPVPDHRDLDIETHGLTIWDLDRTFSVGGFGGKETMTLREVLSRLR
EEECCCCCCCCCCCCCCCCCCCCCEEECCEEEEECCCEEECCCCCCCHHHHHHHHHHHHH
AAYTLKVGSEYTHILDRDERTWLQDRLEAGMPKPTQAEQKYILQKLNAAEAFENFLQTKY
HHEEEEECCHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VGQKRFSLEGAEALIPLMDSAIDTAAGQGLDEVVIGMPHRGRLNVLFNIVGKPLASIFNE
CCCHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
FEGQMEQGQIGGSGDVKYHLGSEGQHLQMFGDGEIKVSLTANPSHLEAVNPVMEGIVRAK
HCCCHHCCCCCCCCCEEEEECCCCCEEEEEECCEEEEEEECCCHHHHHHHHHHHHHHHHH
QDYLDKGVDGKTVVPLLLHGDAAFAGLGIVPETINLAKLRGYDVGGTIHIVVNNQIGFTT
HHHHHCCCCCCEEEEEEEECCHHHHCCCCCCCCCCHHHCCCCCCCCEEEEEEECCCCCEE
TPDSSRSMHYATDYAKAFGCPVFHVNGDDPEAVVWVGQLATEYRRRFGKDVFIDLVCYRL
CCCCCCCEEHHHHHHHHHCCCEEEECCCCCCEEEEHHHHHHHHHHHHCCHHHHHHHHHHH
RGHNEADDPSMTQPKMYELITGRETVRAQYTEDLLGRGDLSNEDAEAVVRDFHDQMESVF
CCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
NEVKEGGKKQAEAQTGITGSQKLPHGLETNISREELLELGQAFANTPEGFNYHPRVAPVA
HHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHH
KKRVSSVTEGGIDWAWGELLAFGSLANSGRLVRLAGEDSRRGTFTQRHAVAIDPATAEEF
HHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCEEEECCCCHHHC
NPLHELAQSKGNNGKFLVYNSALTEYAGMGFEYGYSVGNEDSVVAWEAQFGDFANGAQTI
CHHHHHHHCCCCCCCEEEECCHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHH
IDEYVSSGEAKWGQTSKLILLLPHGYEGQGPDHSSARIERFLQLCAEGSMTVAQPSTPAN
HHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCHH
HFHLLRRHALSDLKRPLVIFTPKSMLRNKAAASAPEDFTEVTKFQSVIDDPNVADAAKVK
HHHHHHHHHHHHHCCCEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHH
KVMLVSGKLYYELAKRKEKDGRDDIAIVRIEMLHPIPFNRISEALAGYPNAEEVLFVQDE
HHHHHCCHHHHHHHHHHCCCCCCCEEEEEEEEECCCCHHHHHHHHCCCCCCCCEEEEECC
PANQGPWPFYQEHLPALIPNMPKMRRVSRRAQSSTATGVAKVHQLEEKQLIDEAFEA
CCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9004499; 12948626 [H]