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The map label for this gene is benK [H]

Identifier: 145295218

GI number: 145295218

Start: 1265998

End: 1267287

Strand: Reverse

Name: benK [H]

Synonym: cgR_1159

Alternate gene names: 145295218

Gene position: 1267287-1265998 (Counterclockwise)

Preceding gene: 145295219

Following gene: 145295216

Centisome position: 38.24

GC content: 56.98

Gene sequence:

>1290_bases
ATGACCACCCCAACCCGCGCAACCAAAAGTGTCGGCACAGTTCTCGCACTCCTGTGGTTCGCAATTGTCCTCGACGGCTT
TGACCTAGTCGTCCTGGGCGCAACAATCCCGTCCATGCTGGAGGATCCCGCGTGGGATCTCACTGCTGGACAGGCCACAC
AGATTTCCACCATCGGCCTCGTCGGCATGACCATTGGCGCACTGACCATCGGTTTCTTAACTGACCGCCTGGGTCGACGC
CGCGTCATGCTGTTCTCTGTGGCAGTATTTTCTGTATTCACTCTCCTGCTGGCATTCACCACCAACGTCCAGCTCTTCAG
CCTGTGGCGTTTCCTCGCAGGTGTTGGCCTTGGTGGAGCACTCCCCACCGCAATTGCCATGGTGACCGAGTTCCGCCCCG
GCACCAAAGCAGGCTCCGCATCCACCACCTTGATGACCGGTTACCACGTCGGCGCAGTAGCAACCGCTTTCCTTGGCCTC
TTCCTTATCGATGGCTTTGGCTGGCACTCCATGTTCATCGCGGGTGCGGTACCAGGTCTGCTCCTGCTACCACTGTTGTA
CTTCTTCCTTCCAGAATCCCCGCAGTACCTCAAAATCTCCGGCAAATTGGATGAGGCGCAGGCAGTTGCAGCATCTTATG
GACTTTCCCTGGATGATGATCTTGATCGCGAACACGAAGAAGAACTCGGCGAGTCCTCCTCACTCTCCTCTCTGTTCAAG
CCATCATTCCGCCGCAACACCCTGGCGATTTGGGGCACCTCATTCATGGGACTCCTCCTGGTCTACGGCCTGAACACGTG
GCTTCCACAGATCATGCGCCAAGCAGACTACGACATGGGTAACTCCCTGGGCTTCCTCATGGTTCTTAACATCGGCGCTG
TAATCGGCCTTTATATTGCAGGGCGATTTGCGGACAAGAATTCTCCTCGCAAAACTGCGCTCGTATGGTTCGTGTTCTCC
GCGATTTTCCTCGCACTGCTCGCTGTTCGGATGCCACTTATCGGTCTGTATGGCATCGTGCTGCTCACCGGCATCTTTGT
GTTCAGCTCCCAGGTACTCATCTACGCCTTCGTTGGTGAGAATCACCCTGCCAAGATGCGTGCAACTGCCATGGGATTCT
CCGCAGGAATTGGTCGCCTCGGCGCGATCTCGGGTCCGTTGCTGGGGGGTCTGCTGGTCAGCGCCAACCTTGCTTACCCA
TGGGGCTTCTTCGCCTTCGCTGGCATTGGACTGCTGGGCGCGCTGATTTTCTCCGCATCGAAGACTCTGAGGCATCGCGA
GAACGCTTAG

Upstream 100 bases:

>100_bases
ATTGCGCTCCGTCCTAGAATCCCAATCCGGCCAACGCTACCTCGCAGAGCAGTACGTTGGGCGCGACCTACCACGCTTCG
AGGTATAAACGCTCGTGTCA

Downstream 100 bases:

>100_bases
GTCTTACTGCTGAATCGACAAAGATCGTTGCACTTTCTTCCCCAAGTTGGTGCAACGATCTTTTTGGGTTATTAGTCTGC
GGAAATACTCCACATCACGC

Product: hypothetical protein

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MTTPTRATKSVGTVLALLWFAIVLDGFDLVVLGATIPSMLEDPAWDLTAGQATQISTIGLVGMTIGALTIGFLTDRLGRR
RVMLFSVAVFSVFTLLLAFTTNVQLFSLWRFLAGVGLGGALPTAIAMVTEFRPGTKAGSASTTLMTGYHVGAVATAFLGL
FLIDGFGWHSMFIAGAVPGLLLLPLLYFFLPESPQYLKISGKLDEAQAVAASYGLSLDDDLDREHEEELGESSSLSSLFK
PSFRRNTLAIWGTSFMGLLLVYGLNTWLPQIMRQADYDMGNSLGFLMVLNIGAVIGLYIAGRFADKNSPRKTALVWFVFS
AIFLALLAVRMPLIGLYGIVLLTGIFVFSSQVLIYAFVGENHPAKMRATAMGFSAGIGRLGAISGPLLGGLLVSANLAYP
WGFFAFAGIGLLGALIFSASKTLRHRENA

Sequences:

>Translated_429_residues
MTTPTRATKSVGTVLALLWFAIVLDGFDLVVLGATIPSMLEDPAWDLTAGQATQISTIGLVGMTIGALTIGFLTDRLGRR
RVMLFSVAVFSVFTLLLAFTTNVQLFSLWRFLAGVGLGGALPTAIAMVTEFRPGTKAGSASTTLMTGYHVGAVATAFLGL
FLIDGFGWHSMFIAGAVPGLLLLPLLYFFLPESPQYLKISGKLDEAQAVAASYGLSLDDDLDREHEEELGESSSLSSLFK
PSFRRNTLAIWGTSFMGLLLVYGLNTWLPQIMRQADYDMGNSLGFLMVLNIGAVIGLYIAGRFADKNSPRKTALVWFVFS
AIFLALLAVRMPLIGLYGIVLLTGIFVFSSQVLIYAFVGENHPAKMRATAMGFSAGIGRLGAISGPLLGGLLVSANLAYP
WGFFAFAGIGLLGALIFSASKTLRHRENA
>Mature_428_residues
TTPTRATKSVGTVLALLWFAIVLDGFDLVVLGATIPSMLEDPAWDLTAGQATQISTIGLVGMTIGALTIGFLTDRLGRRR
VMLFSVAVFSVFTLLLAFTTNVQLFSLWRFLAGVGLGGALPTAIAMVTEFRPGTKAGSASTTLMTGYHVGAVATAFLGLF
LIDGFGWHSMFIAGAVPGLLLLPLLYFFLPESPQYLKISGKLDEAQAVAASYGLSLDDDLDREHEEELGESSSLSSLFKP
SFRRNTLAIWGTSFMGLLLVYGLNTWLPQIMRQADYDMGNSLGFLMVLNIGAVIGLYIAGRFADKNSPRKTALVWFVFSA
IFLALLAVRMPLIGLYGIVLLTGIFVFSSQVLIYAFVGENHPAKMRATAMGFSAGIGRLGAISGPLLGGLLVSANLAYPW
GFFAFAGIGLLGALIFSASKTLRHRENA

Specific function: Probable uptake of benzoate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24308167, Length=435, Percent_Identity=24.8275862068966, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI216548223, Length=311, Percent_Identity=27.9742765273312, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI7662270, Length=199, Percent_Identity=31.6582914572864, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI166064021, Length=350, Percent_Identity=26.8571428571429, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI213021148, Length=412, Percent_Identity=22.5728155339806, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI24497490, Length=361, Percent_Identity=24.9307479224377, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI262399383, Length=162, Percent_Identity=33.9506172839506, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI24497476, Length=387, Percent_Identity=25.0645994832041, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI20070188, Length=387, Percent_Identity=25.0645994832041, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI73695465, Length=163, Percent_Identity=30.6748466257669, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI11415038, Length=263, Percent_Identity=29.277566539924, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI31542327, Length=410, Percent_Identity=25.1219512195122, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI4507005, Length=360, Percent_Identity=23.3333333333333, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87081723, Length=347, Percent_Identity=31.1239193083574, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1786229, Length=379, Percent_Identity=26.3852242744063, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788068, Length=398, Percent_Identity=25.8793969849246, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788074, Length=410, Percent_Identity=26.3414634146341, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87082404, Length=376, Percent_Identity=23.6702127659574, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI87082159, Length=383, Percent_Identity=26.6318537859008, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082231, Length=419, Percent_Identity=23.1503579952267, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32564663, Length=420, Percent_Identity=23.5714285714286, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI193202825, Length=378, Percent_Identity=25.6613756613757, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71986689, Length=378, Percent_Identity=25.6613756613757, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193209824, Length=158, Percent_Identity=30.379746835443, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI19922874, Length=431, Percent_Identity=21.1136890951276, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24640198, Length=301, Percent_Identity=25.5813953488372, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24640196, Length=301, Percent_Identity=25.5813953488372, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24640200, Length=301, Percent_Identity=25.5813953488372, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24648211, Length=232, Percent_Identity=27.5862068965517, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24649618, Length=374, Percent_Identity=24.0641711229947, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI20130083, Length=208, Percent_Identity=29.3269230769231, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI19922616, Length=419, Percent_Identity=22.1957040572792, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI161077756, Length=417, Percent_Identity=23.5011990407674, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24649616, Length=375, Percent_Identity=23.7333333333333, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45898; Mature: 45766

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPTRATKSVGTVLALLWFAIVLDGFDLVVLGATIPSMLEDPAWDLTAGQATQISTIGL
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHEEEHHHHHHHHCCCCCCCCCCCCCHHHHHHH
VGMTIGALTIGFLTDRLGRRRVMLFSVAVFSVFTLLLAFTTNVQLFSLWRFLAGVGLGGA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHH
LPTAIAMVTEFRPGTKAGSASTTLMTGYHVGAVATAFLGLFLIDGFGWHSMFIAGAVPGL
HHHHHHHHHHCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LLLPLLYFFLPESPQYLKISGKLDEAQAVAASYGLSLDDDLDREHEEELGESSSLSSLFK
HHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCHHHHHC
PSFRRNTLAIWGTSFMGLLLVYGLNTWLPQIMRQADYDMGNSLGFLMVLNIGAVIGLYIA
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
GRFADKNSPRKTALVWFVFSAIFLALLAVRMPLIGLYGIVLLTGIFVFSSQVLIYAFVGE
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECC
NHPAKMRATAMGFSAGIGRLGAISGPLLGGLLVSANLAYPWGFFAFAGIGLLGALIFSAS
CCCCHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
KTLRHRENA
HHHHHCCCC
>Mature Secondary Structure 
TTPTRATKSVGTVLALLWFAIVLDGFDLVVLGATIPSMLEDPAWDLTAGQATQISTIGL
CCCCHHHHHHHHHHHHHHHHHHHCCCHHEEEHHHHHHHHCCCCCCCCCCCCCHHHHHHH
VGMTIGALTIGFLTDRLGRRRVMLFSVAVFSVFTLLLAFTTNVQLFSLWRFLAGVGLGGA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHH
LPTAIAMVTEFRPGTKAGSASTTLMTGYHVGAVATAFLGLFLIDGFGWHSMFIAGAVPGL
HHHHHHHHHHCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LLLPLLYFFLPESPQYLKISGKLDEAQAVAASYGLSLDDDLDREHEEELGESSSLSSLFK
HHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCHHHHHC
PSFRRNTLAIWGTSFMGLLLVYGLNTWLPQIMRQADYDMGNSLGFLMVLNIGAVIGLYIA
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
GRFADKNSPRKTALVWFVFSAIFLALLAVRMPLIGLYGIVLLTGIFVFSSQVLIYAFVGE
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECC
NHPAKMRATAMGFSAGIGRLGAISGPLLGGLLVSANLAYPWGFFAFAGIGLLGALIFSAS
CCCCHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
KTLRHRENA
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9294456 [H]